Gökberk Alagöz
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gokberkalagoz.bsky.social
Gökberk Alagöz
@gokberkalagoz.bsky.social
Postdoctoral researcher at MPI-PL, interested in molecular brain evolution and complex trait genetics.
Pinned
Excited to share our latest preprint -and the last chapter of my PhD thesis 🥳- on chimpanzee brain transcriptomics! We present the first-ever spatial transcriptomics data from a great ape brain. Thanks to everyone who made this possible! @profsimonfisher.bsky.social www.biorxiv.org/content/10.1...
Spatial and single-nucleus transcriptomic profile of a chimpanzee frontal pole
Chimpanzees, our closest living relatives, share a vast amount of our genetic code, with the majority of differences found in non-coding regions of the genome. Functional and gene regulatory differenc...
www.biorxiv.org
Reposted by Gökberk Alagöz
Interrogating the Regulatory Function of HAQERs during Human Cortical Development https://www.biorxiv.org/content/10.1101/2025.11.30.691411v1
December 1, 2025 at 10:31 PM
Reposted by Gökberk Alagöz
Abstract submission & Award applications for SMBE 2026 are now open!

Submit your research and apply for SMBE awards via the submission portal.
📝 Read more & submit here: smbe2026.org/abstracts

And symposium selection is now finalized!
👉 See all accepted symposia: smbe2026.org/programme

#SMBE2026
December 1, 2025 at 9:52 AM
Reposted by Gökberk Alagöz
New in Science, Macaques tap to the beat.

Very cool study for its main result and its null one: consistent with nearly every other comparative study of music, monkeys don't differentiate beats by their relative strength—which even young children do innately. Monkeys have rhythm but not meter!
Monkeys have rhythm
Synchronizing movements to music is a hallmark of human culture, but its evolutionary and neurobiological origins remain unknown. This ability requires (i) extracting a steady rhythmic pulse, or beat,...
www.science.org
November 28, 2025 at 11:45 PM
Reposted by Gökberk Alagöz
PhD position available for theoretical and statistical modeling in my joint @gevol.bsky.social project with @luisapallares.bsky.social on the evolution of transcriptional variability and its role in adaptation and evolutionary innovation.
See
job-portal.lmu.de/jobposting/6...
PhD candidate in biology — theoretical and statistical modeling (m/f/x)
job-portal.lmu.de
November 26, 2025 at 2:37 PM
"...These features may be related to the metabolic demands of human cognition and would be predicted to differ in language‐associated regions of the brains of language-trained apes as a reflection of adaptive neurobiological changes in response to heightened communicative demands."
onlinelibrary.wiley.com
November 28, 2025 at 7:53 PM
Reposted by Gökberk Alagöz
🚨 Palaeo jobs alert!! 🚨

Two(!!) postdoc positions available in Cambridge!

1. Human Evolutionary Anatomy: cam.ac.uk/jobs/researc...
2. Evolutionary Biomechanics: cam.ac.uk/jobs/researc...

As part of the @erc.europa.eu funded STEPS project!
November 28, 2025 at 11:38 AM
Reposted by Gökberk Alagöz
Please check out and RT this new position for an exciting collaborative project with @boninlab.bsky.social and @franckp.bsky.social on the links between human-specific mechanisms and neurodevelopmental disorders in cortical circuits.
Please repost widely. @vanderhaeghenp2.bsky.social and I are hiring a postdoc with expertise in sensory physiology and in vivo circuit imaging/manipulation. The project centers on human-specific brain development and SYNGAP1-related disorders. Call closing soon—apply ASAP
jobs.vib.be/j/119852/pos...
Postdoctoral Fellow / PhD Student in Systems Neuroscience - VIB
The Laboratory of Cortical Information Processing | Vision to Action at NERF (www.nerf.be) invites applications for a Postdoctoral Fellow or PhD Student to work on a new research project funded by the...
jobs.vib.be
November 27, 2025 at 10:18 AM
Reposted by Gökberk Alagöz
Out now: we’re happy to share our new preprint on CroCoNet (Cross-species Comparison of Networks), a framework for robust comparative network analyses.
👉 doi.org/10.1101/2025...
November 25, 2025 at 4:02 PM
Reposted by Gökberk Alagöz
Join us on Dec. 2 for a webinar on the major advances in basal ganglia mapping, including cross-species cellular mapping and open-access visualization tools.

📅 Dec. 2, 9-10:30am PT
📍 Online
🔗 Register: https://alleninstitute.org/events/neuroscience-cell-types-webinars/

#studyBRAIN #neuroskyence
November 25, 2025 at 4:50 PM
Reposted by Gökberk Alagöz
Comparative Analysis of FOXP2 Expression in the Thalamus of Mice, Rats, and Macaques: Implications for the Evolution of Language Circuits. https://www.biorxiv.org/content/10.1101/2025.11.23.689322v1
November 24, 2025 at 8:15 AM
Reposted by Gökberk Alagöz
Origins of language, one of humanity’s most distinctive traits, may be best explained as a unique convergence of multiple capacities each with its own evolutionary history, involving intertwined roles of biology & culture. This framing can expand research horizons. A 🧵 on our @science.org paper.🧪1/n
What enables human language? A biocultural framework
Explaining the origins of language is a key challenge in understanding ourselves as a species. We present an empirical framework that draws on synergies across fields to facilitate robust studies of l...
www.science.org
November 23, 2025 at 11:54 AM
Reposted by Gökberk Alagöz
🚨RA/PhD position available in evolutionary neurobiology 🚨

Working on a deep dive into circuit changes during mushroom body expansion in Heliconius butterflies @camzoology.bsky.social

- employment benefits
- 4 years funding
- 1000% fun

Deadline: 14/1/2026

Details:
www.cam.ac.uk/jobs/researc...
November 21, 2025 at 2:31 PM
Reposted by Gökberk Alagöz
Putting aside the deeper issues of why this analysis was done and how it has been promoted, the choice to broadcast a tv show before releasing a preprint should make people skeptical of the results. How can one be sure of their scientific claims?
As I told the CNN, without details and data it is not possible to assess the claims.

More importantly, the scientific value of this media campaign, balanced against the possible stigmatization of individuals with these real conditions today, is highly questionable. edition.cnn.com/2025/11/13/s...
Researchers say they have verified and sequenced Hitler’s DNA – and found a genetic disorder | CNN
Analysis of Adolf Hitler’s DNA reveals he may have had a rare genetic disorder that can delay puberty.
edition.cnn.com
November 15, 2025 at 3:19 AM
Reposted by Gökberk Alagöz
Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here.

www.cam.ac.uk/jobs/faculty...
Faculty Position in Computational Biology
Applications are invited for an Assistant/ Associate Professorship in Computational Biology to commence on 1 April 2026 or shortly thereafter. This is a joint post between the Department of Applied
www.cam.ac.uk
November 11, 2025 at 9:05 PM
Reposted by Gökberk Alagöz
Which human brain circuits are implicated in neurodevelopmental conditions? We bridged human genetics, spatial transcriptomics and neurodevelopment to discover the convergence of autism-associated genes in the developing human thalamus! www.biorxiv.org/content/10.1...
November 11, 2025 at 10:55 AM
Reposted by Gökberk Alagöz
Our new manuscript, led by Emily Corrigan, examines inhibitory neuron diversity across approximately 160 million years of evolutionary divergence, as part of BRAIN Initiative Cell Atlas Network (BICAN) developing brain atlas package: www.nature.com/articles/s41...
Conservation and alteration of mammalian striatal interneurons - Nature
An analysis of cell-type diversity in brain samples from a variety of mammalian species, both during development and in adult animals, reveals that the TAC3 initial class of striatal interneurons is c...
www.nature.com
November 7, 2025 at 6:06 PM
Reposted by Gökberk Alagöz
Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com

www.nature.com/articles/s41...
Spatial dynamics of brain development and neuroinflammation - Nature
A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.
www.nature.com
November 5, 2025 at 4:03 PM
Reposted by Gökberk Alagöz
This is 🤯

All publicly available. Looks like an amazing new histology-based human probabilistic atlas and parcellation tool.

#neuroskyence #mri #brainmapping

A probabilistic histological atlas of the human brain for MRI segmentation | Nature share.google/5AD0iW7pxgb4...
A probabilistic histological atlas of the human brain for MRI segmentation - Nature
NextBrain is an open source, probabilistic atlas of the entire human brain, assembled using artificial-intelligence-enabled registration and segmentation methods to reconstruct the multimodal serial h...
share.google
November 6, 2025 at 5:35 AM
Reposted by Gökberk Alagöz
50 years ago, King & Wilson published a foundational paper that underlies the cis-regulatory paradigm (CRP) of #DevoEvo #EvoDevo, i.e., that *almost* all morphological evolution is driven by mutations in regulatory elements, rather than proteins, and it all arose from simple misunderstanding 🧪 🧵
October 29, 2025 at 12:35 AM
Reposted by Gökberk Alagöz
PhD-opening in our ancient genomics lab this year, apply below!

We work on:
📜 Genetic history integrated with archaeology and history
📈 Natural selection and trait genetics
🐺 Evolutionary genomics of dogs and wolves
🦠 Ancient pathogen genomics
💀 Hominin evolution and ancient proteomics
Motivated graduates with backgrounds in biological or biomedical sciences, physics, chemistry, mathematics, engineering and/or computer science are invited to apply to our 4-year fully funded PhD programme.

Apply by 05 November 2025

www.crick.ac.uk/careers-and-...
PhD students
Our PhD programme attracts the brightest scientific minds and is an opportunity for talented people to embark on their career in biomedical research.
www.crick.ac.uk
October 9, 2025 at 3:51 PM
Reposted by Gökberk Alagöz
Come join us for a 4-year PhD on effects of rare gene disruptions involved in speech disorder, investigated in human neuronal models (via gene-editing, tissue culture, brain organoids, high-res microscopy, transcriptomics, epigenomics).
More info: www.mpi.nl/imprs-phd-fe...
#AcademicJobs #PhDJobs
🧬🧪
October 22, 2025 at 3:43 PM
Reposted by Gökberk Alagöz
A high-coverage genome from a 200,000-year-old Denisovan https://www.biorxiv.org/content/10.1101/2025.10.20.683404v1
October 20, 2025 at 3:33 PM
Reposted by Gökberk Alagöz
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
October 15, 2025 at 3:53 PM
Reposted by Gökberk Alagöz
A species of lungfish found in South America has claimed the title of the animal with the biggest genome sequenced so far.

Learn more on #WorldAnimalDay: https://scim.ag/46OMl6v
October 4, 2025 at 8:54 PM