Guillaume Thibault
@gthibault.bsky.social
Associate Professor www.thibaultlab.com at Nanyang Technological University Singapore 🇸🇬. Endoplasmic Reticulum Stress and Unfolded Protein Response in health and diseases • Co-PI Mechanobiology Institute • MBoC Assoc Editor • University of Toronto alumni
So glad to see this paper out! A small but rewarding contribution from our side. It was a fantastic experience collaborating with @kimingeneva.bsky.social, @ronni.bsky.social, and this great global team on such an interesting manuscript.
Lactic acid lover? Check out @ronni.bsky.social 's new work in
@cp-cellhostmicrobe.bsky.social showing how Enterococcus faecalis-derived LA suppresses macrophage activation, in turn promoting bacterial persistence and polymicrobial wound infection in vivo.
www.sciencedirect.com/science/arti...
@cp-cellhostmicrobe.bsky.social showing how Enterococcus faecalis-derived LA suppresses macrophage activation, in turn promoting bacterial persistence and polymicrobial wound infection in vivo.
www.sciencedirect.com/science/arti...
Enterococcus faecalis-derived lactic acid suppresses macrophage activation to facilitate persistent and polymicrobial wound infections
Macrophage activation is essential for innate immunity and antimicrobial defense. We show that Enterococcus faecalis suppresses macrophage activation …
www.sciencedirect.com
January 28, 2026 at 8:13 AM
So glad to see this paper out! A small but rewarding contribution from our side. It was a fantastic experience collaborating with @kimingeneva.bsky.social, @ronni.bsky.social, and this great global team on such an interesting manuscript.
Reposted by Guillaume Thibault
Enterococcus fans: Check out our latest on E. faecalis EET, advancing our understanding of both the fundamental physiology of this bug and new mechanisms of its virulence. This is the product of a thrilling collaboration with friends in Singapore @gthibault.bsky.social led by @aarontan.bsky.social.
We’ve discovered how the superbug E. faecalis prevents chronic wounds from healing.
It’s not a toxin. It’s metabolism.
The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place.
doi.org/10.1126/sciadv.aeb5297
It’s not a toxin. It’s metabolism.
The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place.
doi.org/10.1126/sciadv.aeb5297
Enterococcus faecalis redox metabolism activates the unfolded protein response to impair wound healing
E. faecalis EET generates ROS, which induces the UPR in keratinocytes, inhibiting in vitro migration.
doi.org
January 17, 2026 at 5:57 AM
Enterococcus fans: Check out our latest on E. faecalis EET, advancing our understanding of both the fundamental physiology of this bug and new mechanisms of its virulence. This is the product of a thrilling collaboration with friends in Singapore @gthibault.bsky.social led by @aarontan.bsky.social.
We’ve discovered how the superbug E. faecalis prevents chronic wounds from healing.
It’s not a toxin. It’s metabolism.
The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place.
doi.org/10.1126/sciadv.aeb5297
It’s not a toxin. It’s metabolism.
The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place.
doi.org/10.1126/sciadv.aeb5297
Enterococcus faecalis redox metabolism activates the unfolded protein response to impair wound healing
E. faecalis EET generates ROS, which induces the UPR in keratinocytes, inhibiting in vitro migration.
doi.org
January 17, 2026 at 1:26 AM
We’ve discovered how the superbug E. faecalis prevents chronic wounds from healing.
It’s not a toxin. It’s metabolism.
The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place.
doi.org/10.1126/sciadv.aeb5297
It’s not a toxin. It’s metabolism.
The bacteria use extracellular electron transport (EET) to electrochemically generate ROS, effectively "freezing" skin cells in place.
doi.org/10.1126/sciadv.aeb5297
Reposted by Guillaume Thibault
We’re hiring!
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!
Details below👇
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!
Details below👇
Journal of Cell Science @jcellsci.bsky.social is recruiting an enthusiastic and motivated Reviews Editor. An exciting opportunity for a talented scientific editor to make a contribution to an important journal in the field of #cellbiology. Deadline 2 Feb.
More at: www.biologists.com/about-us/wor...
More at: www.biologists.com/about-us/wor...
Work for us
Working for us We’re always looking for talented and motivated people to work as part of our close-knit team. Roles range from editorial to production, marketing to event co-ordination, HR to accounts...
www.biologists.com
January 9, 2026 at 10:13 AM
We’re hiring!
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!
Details below👇
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!
Details below👇
Reposted by Guillaume Thibault
Issue 24 is complete
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
January 6, 2026 at 10:49 AM
Issue 24 is complete
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
Reposted by Guillaume Thibault
What's it like being Editor-in-chief of @jcellsci.bsky.social? doi.org/10.1242/jcs....
At the helm of JCS – Editors-in-Chief past, present… and future
The Editor-in-Chief (EIC) of Journal of Cell Science plays a key role in defining the overall vision of the journal, helping to decide on journal strategy, policy and priorities, and overseeing all co...
doi.org
December 22, 2025 at 10:33 AM
What's it like being Editor-in-chief of @jcellsci.bsky.social? doi.org/10.1242/jcs....
Reposted by Guillaume Thibault
Our Editors will be attending #CellBio2025 @ascbiology.bsky.social @embo.org.
Reach out to @seemagrewal.bsky.social and Amelia Glazier to discuss JCS, @focalplane.bsky.social and our other @biologists.bsky.social initiatives.
Reach out to @seemagrewal.bsky.social and Amelia Glazier to discuss JCS, @focalplane.bsky.social and our other @biologists.bsky.social initiatives.
December 3, 2025 at 12:13 PM
Our Editors will be attending #CellBio2025 @ascbiology.bsky.social @embo.org.
Reach out to @seemagrewal.bsky.social and Amelia Glazier to discuss JCS, @focalplane.bsky.social and our other @biologists.bsky.social initiatives.
Reach out to @seemagrewal.bsky.social and Amelia Glazier to discuss JCS, @focalplane.bsky.social and our other @biologists.bsky.social initiatives.
Ready for a transformative research journey? 🚀
Join the vibrant, interdisciplinary PhD programmes at NTU College of Science in Singapore! We offer fully funded scholarships.
Hear from our students and faculty in the video below 👇
youtu.be/JeZHiXu3fgE
Join the vibrant, interdisciplinary PhD programmes at NTU College of Science in Singapore! We offer fully funded scholarships.
Hear from our students and faculty in the video below 👇
youtu.be/JeZHiXu3fgE
NTU College of Science PhD opportunities
YouTube video by College of Science NTU
youtu.be
November 5, 2025 at 3:00 AM
Ready for a transformative research journey? 🚀
Join the vibrant, interdisciplinary PhD programmes at NTU College of Science in Singapore! We offer fully funded scholarships.
Hear from our students and faculty in the video below 👇
youtu.be/JeZHiXu3fgE
Join the vibrant, interdisciplinary PhD programmes at NTU College of Science in Singapore! We offer fully funded scholarships.
Hear from our students and faculty in the video below 👇
youtu.be/JeZHiXu3fgE
Thank you @jcellsci.bsky.social! It was so much fun chatting with Editor @seemagrewal.bsky.social about my journey, research, and advice for junior scientists.
It’s great that it reads just like our conversation flowed. I sincerely hope it resonates with trainees out there!
Read the interview 👇
It’s great that it reads just like our conversation flowed. I sincerely hope it resonates with trainees out there!
Read the interview 👇
Interview with Guillaume Thibault @gthibault.bsky.social – President of the Society for Cell Biology Singapore
We chatted about Guillaume’s route into academia, his research and his advice for junior scientists.
journals.biologists.com/jcs/article/...
We chatted about Guillaume’s route into academia, his research and his advice for junior scientists.
journals.biologists.com/jcs/article/...
October 23, 2025 at 5:16 AM
Thank you @jcellsci.bsky.social! It was so much fun chatting with Editor @seemagrewal.bsky.social about my journey, research, and advice for junior scientists.
It’s great that it reads just like our conversation flowed. I sincerely hope it resonates with trainees out there!
Read the interview 👇
It’s great that it reads just like our conversation flowed. I sincerely hope it resonates with trainees out there!
Read the interview 👇
Reposted by Guillaume Thibault
Internal documents reviewed by the New York Times reveal Amazon's goal to replace 600,000 jobs with robots.
When we support our local businesses, we create a more stable economy—one not at the whim of billionaires. Support your indie bookshop today and every day 💓
When we support our local businesses, we create a more stable economy—one not at the whim of billionaires. Support your indie bookshop today and every day 💓
October 22, 2025 at 6:31 PM
Internal documents reviewed by the New York Times reveal Amazon's goal to replace 600,000 jobs with robots.
When we support our local businesses, we create a more stable economy—one not at the whim of billionaires. Support your indie bookshop today and every day 💓
When we support our local businesses, we create a more stable economy—one not at the whim of billionaires. Support your indie bookshop today and every day 💓
Reposted by Guillaume Thibault
As part of our commitment to Open Access, we support libraries, consortia and researchers. For #OAWeek, we share a recent webinar that includes tips and recommendations for navigating the editorial process and publishing #OA
youtu.be/PjD5QQ-p0Xg
#OAWeek25
youtu.be/PjD5QQ-p0Xg
#OAWeek25
Publishing with The Company of Biologists: supporting biologists, inspiring biology
YouTube video by The Company of Biologists
youtu.be
October 22, 2025 at 11:23 AM
As part of our commitment to Open Access, we support libraries, consortia and researchers. For #OAWeek, we share a recent webinar that includes tips and recommendations for navigating the editorial process and publishing #OA
youtu.be/PjD5QQ-p0Xg
#OAWeek25
youtu.be/PjD5QQ-p0Xg
#OAWeek25
Reposted by Guillaume Thibault
Super interesting! I’m curious what’s considered a “high-fiber” diet for people. Looks like the mice were tested on either no fiber or all carbs replaced with fiber? 🌾VS🍞 #microbiomesky 🧪🦠
If you missed Dr Chudan Xu's talk on what happens when we don't eat enough fibre, the preprint is now live 👇
www.medrxiv.org/content/10.1...
#EESMicrobiome @events.embl.org
www.medrxiv.org/content/10.1...
#EESMicrobiome @events.embl.org
September 21, 2025 at 12:45 PM
Super interesting! I’m curious what’s considered a “high-fiber” diet for people. Looks like the mice were tested on either no fiber or all carbs replaced with fiber? 🌾VS🍞 #microbiomesky 🧪🦠
Reposted by Guillaume Thibault
Campus housing 🏡 a big bonus! Plus more than 10 canteens 🥡(we haven't cooked a single meal for a year haha)! My American husband also likes it here :)
🚨 JOB ALERT!
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
September 5, 2025 at 2:56 AM
Campus housing 🏡 a big bonus! Plus more than 10 canteens 🥡(we haven't cooked a single meal for a year haha)! My American husband also likes it here :)
Reposted by Guillaume Thibault
And salary? Due to low taxes & subsidized housing, our offer provides a quality of life comparable to a US$215k - $300k salary in major US academic hubs like NYC or the Bay Area. A great deal for your science and your life.
September 2, 2025 at 11:45 AM
And salary? Due to low taxes & subsidized housing, our offer provides a quality of life comparable to a US$215k - $300k salary in major US academic hubs like NYC or the Bay Area. A great deal for your science and your life.
Reposted by Guillaume Thibault
What does our start-up package mean in US terms? It's equivalent to $3.8M package at a top US university. Why? We fully cover PI salary costs and 5 PhD scholarships, so your research grant is for research.
September 2, 2025 at 11:45 AM
What does our start-up package mean in US terms? It's equivalent to $3.8M package at a top US university. Why? We fully cover PI salary costs and 5 PhD scholarships, so your research grant is for research.
Reposted by Guillaume Thibault
🚨 JOB ALERT!
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
September 2, 2025 at 11:45 AM
🚨 JOB ALERT!
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
Reposted by Guillaume Thibault
Your research future starts at NTU Singapore! We're recruiting for fully-funded PhDs & prestigious Postdoc fellowships. Join our info sessions across the US this Sept to learn more about launching your career at a world-class university. #PhD #PostdocJobs
Register 👇
forms.office.com/r/HYfKgmcAa0
Register 👇
forms.office.com/r/HYfKgmcAa0
September 2, 2025 at 11:46 AM
Your research future starts at NTU Singapore! We're recruiting for fully-funded PhDs & prestigious Postdoc fellowships. Join our info sessions across the US this Sept to learn more about launching your career at a world-class university. #PhD #PostdocJobs
Register 👇
forms.office.com/r/HYfKgmcAa0
Register 👇
forms.office.com/r/HYfKgmcAa0
Reposted by Guillaume Thibault
Especially this AI4X postdoc fellowship! ✨🤖 www.ntu.edu.sg/research/res...
September 2, 2025 at 12:02 PM
Especially this AI4X postdoc fellowship! ✨🤖 www.ntu.edu.sg/research/res...
Your research future starts at NTU Singapore! We're recruiting for fully-funded PhDs & prestigious Postdoc fellowships. Join our info sessions across the US this Sept to learn more about launching your career at a world-class university. #PhD #PostdocJobs
Register 👇
forms.office.com/r/HYfKgmcAa0
Register 👇
forms.office.com/r/HYfKgmcAa0
September 2, 2025 at 11:46 AM
Your research future starts at NTU Singapore! We're recruiting for fully-funded PhDs & prestigious Postdoc fellowships. Join our info sessions across the US this Sept to learn more about launching your career at a world-class university. #PhD #PostdocJobs
Register 👇
forms.office.com/r/HYfKgmcAa0
Register 👇
forms.office.com/r/HYfKgmcAa0
🚨 JOB ALERT!
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
September 2, 2025 at 11:45 AM
🚨 JOB ALERT!
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack
Register 👇 www.cognitoforms.com/Ntu18/NTUSin...
Reposted by Guillaume Thibault
Exciting news — I am super honored to receive the 2025 MBoC Early Career Paper Award 🎉 My very first award 😊
www.molbiolcell.org/doi/10.1091/...
Couldn’t imagine a better send-off as I just wrapped up my postdoc at UNC and get ready to start a lab in Münster this fall 😃
www.molbiolcell.org/doi/10.1091/...
Couldn’t imagine a better send-off as I just wrapped up my postdoc at UNC and get ready to start a lab in Münster this fall 😃
September 1, 2025 at 10:59 AM
Exciting news — I am super honored to receive the 2025 MBoC Early Career Paper Award 🎉 My very first award 😊
www.molbiolcell.org/doi/10.1091/...
Couldn’t imagine a better send-off as I just wrapped up my postdoc at UNC and get ready to start a lab in Münster this fall 😃
www.molbiolcell.org/doi/10.1091/...
Couldn’t imagine a better send-off as I just wrapped up my postdoc at UNC and get ready to start a lab in Münster this fall 😃
Reposted by Guillaume Thibault
MIT News: news.mit.edu/2024/human-g... — Sharing our new publication in Cell Genomics: cell.com/cell-genomic... about why our human gut microbiome rarely updates its CRISPR defense systems!
Bacteria in the human gut rarely update their CRISPR defense systems
MIT research finds intestinal bacterial interact much less often with viruses that trigger immunity updates than bacteria in the lab. The results will help to assess gut microbiome health.
news.mit.edu
August 30, 2025 at 1:54 AM
MIT News: news.mit.edu/2024/human-g... — Sharing our new publication in Cell Genomics: cell.com/cell-genomic... about why our human gut microbiome rarely updates its CRISPR defense systems!
Pleased to welcome my new colleague from SBS @ NTU Singapore, Anni Zhang @annizlab.bsky.social, to the platform.
She is a dynamic addition to our school, and it's always a pleasure to discuss science with her. Looking forward to her contributions here. Find more about her lab 👇
She is a dynamic addition to our school, and it's always a pleasure to discuss science with her. Looking forward to her contributions here. Find more about her lab 👇
Hi everyone, I'm a bioinformatician & microbiologist. My new lab @Nanyang Technological University uncovers diverse microbial mechanisms (regulatory networks, selective sweeps, host-microbe interactions, ...) via machine learning! genomiverse.net
Requirements
genomiverse.net
August 30, 2025 at 2:29 AM
Pleased to welcome my new colleague from SBS @ NTU Singapore, Anni Zhang @annizlab.bsky.social, to the platform.
She is a dynamic addition to our school, and it's always a pleasure to discuss science with her. Looking forward to her contributions here. Find more about her lab 👇
She is a dynamic addition to our school, and it's always a pleasure to discuss science with her. Looking forward to her contributions here. Find more about her lab 👇
Reposted by Guillaume Thibault
Very honored to receive the Royal Society Research Culture Award - this represents the work of a great team who've worked non-stop since we launched bioRxiv in 2013 royalsociety.org/news/2025/08... www.cshl.edu/inglis-and-s...
Invisibility cloak pioneer Sir John Pendry awarded Royal Society’s top prize | Royal Society
The Royal Society announces the medals and awards recipients 2025
royalsociety.org
August 27, 2025 at 1:37 PM
Very honored to receive the Royal Society Research Culture Award - this represents the work of a great team who've worked non-stop since we launched bioRxiv in 2013 royalsociety.org/news/2025/08... www.cshl.edu/inglis-and-s...
Reposted by Guillaume Thibault
The endoplasmic reticulum donates lipids through a tunnel-like protein to help lysosomes expand.
Learn more in a new #SciencePerspective: https://scim.ag/45GWQrS
Learn more in a new #SciencePerspective: https://scim.ag/45GWQrS
A protein tunnel helps stressed lysosomes swell
The endoplasmic reticulum donates lipids through a tunnel-like protein to help lysosomes expand
scim.ag
August 27, 2025 at 1:07 PM
The endoplasmic reticulum donates lipids through a tunnel-like protein to help lysosomes expand.
Learn more in a new #SciencePerspective: https://scim.ag/45GWQrS
Learn more in a new #SciencePerspective: https://scim.ag/45GWQrS