Jaana Mannik
@jaanamannik.bsky.social
Cell & molecular biologist. Biophysics research @Univ. of Tennessee, Knoxville.
volweb.utk.edu/~jmannik/
Unraveling the self-assembly process of cell division machinery in E. coli.
volweb.utk.edu/~jmannik/
Unraveling the self-assembly process of cell division machinery in E. coli.
Reposted by Jaana Mannik
To all trainees interested in channels and transporters: the joint FEBS/EMBO course will go ahead in Erice, Italy from May 13-19 2026:
network.febs.org/posts/new-jo...
Further details to come soon.
Please share and repost.
network.febs.org/posts/new-jo...
Further details to come soon.
Please share and repost.
November 26, 2025 at 4:17 PM
To all trainees interested in channels and transporters: the joint FEBS/EMBO course will go ahead in Erice, Italy from May 13-19 2026:
network.febs.org/posts/new-jo...
Further details to come soon.
Please share and repost.
network.febs.org/posts/new-jo...
Further details to come soon.
Please share and repost.
Reposted by Jaana Mannik
Let’s wrap things up: Open and closed hypernucleosomes in Asgard archaea
Let’s wrap things up: Open and closed hypernucleosomes in Asgard archaea
Asgard archaea are widely considered the closest living relatives of eukaryotes. In this issue of Molecular Cell, Ranawat et al. report high-resolution structures of hypernucleosomes formed by the hodarchaeal HHoB histone, disclosing open and closed chromatin conformations.
dlvr.it
November 26, 2025 at 8:14 PM
Let’s wrap things up: Open and closed hypernucleosomes in Asgard archaea
Reposted by Jaana Mannik
Happy to share a new preprint from the lab: Marko became interested in whether the disordered linker of FtsZ might influence how the protein organizes into the Z-ring. And this led to some surprising findings!
Preprint: www.biorxiv.org/content/10.1...
Preprint: www.biorxiv.org/content/10.1...
Charge segregation in the C-terminal linker of FtsZ enables Z-ring scaling with prokaryotic cell width
Bacterial cytokinesis is orchestrated by the Z-ring, a cytoskeletal structure formed by treadmilling filaments of the tubulin-like GTPase FtsZ. During assembly, filament curvature must match the cell ...
www.biorxiv.org
November 26, 2025 at 9:29 PM
Happy to share a new preprint from the lab: Marko became interested in whether the disordered linker of FtsZ might influence how the protein organizes into the Z-ring. And this led to some surprising findings!
Preprint: www.biorxiv.org/content/10.1...
Preprint: www.biorxiv.org/content/10.1...
Reposted by Jaana Mannik
We are hiring a 2-year postdoctoral researcher to join our Membrane Biophysics team at the CBS in Montpellier. Join us to reinvent Atomic Force Microscopy to image the most common interface on our planet: the surface of water @membranesbiophy.bsky.social @cbsmontpellier.bsky.social
November 25, 2025 at 1:04 PM
We are hiring a 2-year postdoctoral researcher to join our Membrane Biophysics team at the CBS in Montpellier. Join us to reinvent Atomic Force Microscopy to image the most common interface on our planet: the surface of water @membranesbiophy.bsky.social @cbsmontpellier.bsky.social
Reposted by Jaana Mannik
Our review is now available #OpenAccess online and as formatted PDF doi.org/10.1093/fems...
Delighted that our review on resistance to last-resort antibiotics in Enterococci has been published in FEMS Microbiology Reviews
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
academic.oup.com/femsre/advan... (accepted manuscript version)
TL;DR: the Enterococci are really good at evolving resistance to antibiotics in new and creative ways.
Resistance to last-resort antibiotics in enterococci
Abstract. The genus Enterococcus comprises a diverse group of species, many of which are commensal members of the gut microbiota of humans and animals. The
academic.oup.com
November 26, 2025 at 1:57 PM
Our review is now available #OpenAccess online and as formatted PDF doi.org/10.1093/fems...
Reposted by Jaana Mannik
rdcu.be/eRxNf here our new study on the characterization of the lipopolysaccharide holotranslocon, LptDE and the newly identified subunits LptM and LptY. Great collaboration with @fronzeslab.bsky.social @pstansfeld.bsky.social @JulienMarcoux @YvesQuentin
Structural basis of lipopolysaccharide assembly by the outer membrane translocon holo-complex
Nature Communications - The asymmetric distribution of lipopolysaccharide (LPS) on the surface of the bacterial outer membrane is essential and crucial for antibiotic resistance. Here, authors...
rdcu.be
November 24, 2025 at 4:08 PM
rdcu.be/eRxNf here our new study on the characterization of the lipopolysaccharide holotranslocon, LptDE and the newly identified subunits LptM and LptY. Great collaboration with @fronzeslab.bsky.social @pstansfeld.bsky.social @JulienMarcoux @YvesQuentin
Reposted by Jaana Mannik
My lab is hiring postdocs! We combine AI, protein structure prediction and comparison, and high-throughput virology to study the virus-host conflict.
You can read more about my lab's research here: jasonnomburg.com/research/
Apply here to join us in lovely Vienna! aithyra.onlyfy.jobs/job/0khkxp82
You can read more about my lab's research here: jasonnomburg.com/research/
Apply here to join us in lovely Vienna! aithyra.onlyfy.jobs/job/0khkxp82
The Starting Principal Investigators at #AITHYRA the Research Institute for Biomedical Artificial Intelligence of the OeAW in Vienna invite outstanding candidates to apply for postdoctoral positions in the field of AI/ML & Life Sciences.
www.oeaw.ac.at/aithyra/post...
Please apply by 20 Nov 2025!
www.oeaw.ac.at/aithyra/post...
Please apply by 20 Nov 2025!
October 20, 2025 at 1:03 PM
My lab is hiring postdocs! We combine AI, protein structure prediction and comparison, and high-throughput virology to study the virus-host conflict.
You can read more about my lab's research here: jasonnomburg.com/research/
Apply here to join us in lovely Vienna! aithyra.onlyfy.jobs/job/0khkxp82
You can read more about my lab's research here: jasonnomburg.com/research/
Apply here to join us in lovely Vienna! aithyra.onlyfy.jobs/job/0khkxp82
Reposted by Jaana Mannik
The hinge bypass gate paper is finally out! doi.org/10.1038/s414...
We show how loop-extruding SMC complexes can maintain DNA entrapment while bypassing obstacles on DNA — including transcription machinery & potentially other SMCs.
A lucky convergence of 3 projects lead to the initial discovery!
We show how loop-extruding SMC complexes can maintain DNA entrapment while bypassing obstacles on DNA — including transcription machinery & potentially other SMCs.
A lucky convergence of 3 projects lead to the initial discovery!
The SMC Hinge is a Selective Gate for Obstacle Bypass - Nature Communications
SMC complexes are ring-shaped motors that fold DNA by extruding loops, but how they navigate large DNA obstacles is unclear. Here, Liu et al., show that SMC complexes bypass obstacles by threading obs...
doi.org
November 25, 2025 at 3:26 PM
The hinge bypass gate paper is finally out! doi.org/10.1038/s414...
We show how loop-extruding SMC complexes can maintain DNA entrapment while bypassing obstacles on DNA — including transcription machinery & potentially other SMCs.
A lucky convergence of 3 projects lead to the initial discovery!
We show how loop-extruding SMC complexes can maintain DNA entrapment while bypassing obstacles on DNA — including transcription machinery & potentially other SMCs.
A lucky convergence of 3 projects lead to the initial discovery!
Reposted by Jaana Mannik
What led to the emergence of the first states, thousands of years ago?
People often say agriculture, but the first large-scale societies didn't appear until 4000 years after the advent of agriculture. The answer may be growing grain, specifically. 🧪 #history
www.newscientist.com/article/2505...
People often say agriculture, but the first large-scale societies didn't appear until 4000 years after the advent of agriculture. The answer may be growing grain, specifically. 🧪 #history
www.newscientist.com/article/2505...
Easily taxed grains were crucial to the birth of the first states
The cultivation of wheat, barley and maize, which are easily stored and taxed, seems to have led to the emergence of large societies, rather than agriculture generally
www.newscientist.com
November 25, 2025 at 11:46 AM
What led to the emergence of the first states, thousands of years ago?
People often say agriculture, but the first large-scale societies didn't appear until 4000 years after the advent of agriculture. The answer may be growing grain, specifically. 🧪 #history
www.newscientist.com/article/2505...
People often say agriculture, but the first large-scale societies didn't appear until 4000 years after the advent of agriculture. The answer may be growing grain, specifically. 🧪 #history
www.newscientist.com/article/2505...
Reposted by Jaana Mannik
Want to join the Chromatin Biophysics team? We are recruiting a postdoc!
⬇️⬇️⬇️
Apply through the website here www.ru.nl/en/working-a...
⬇️⬇️⬇️
Apply through the website here www.ru.nl/en/working-a...
Postdoc Position: Cellular Biophysics | Radboud University
Do you want to work as a Postdoc Position: Cellular Biophysics at the Faculty of Science? Check our vacancy!
www.ru.nl
November 25, 2025 at 1:06 PM
Want to join the Chromatin Biophysics team? We are recruiting a postdoc!
⬇️⬇️⬇️
Apply through the website here www.ru.nl/en/working-a...
⬇️⬇️⬇️
Apply through the website here www.ru.nl/en/working-a...
Reposted by Jaana Mannik
Really cool paper from @vincentdebakker.bsky.social @jonbakerlab.bsky.social now published @natcomms.nature.com #MicroSky www.nature.com/articles/s41...
Multi-omics profiling reveals atypical sugar utilization and a key membrane composition regulator in Streptococcus pneumoniae - Nature Communications
The pathogen Streptococcus pneumoniae can adapt to diverse microenvironments in the human body. Here, De Bakker et al. study these adaptation responses, showing unusual sugar utilization and identifyi...
www.nature.com
November 25, 2025 at 1:44 PM
Really cool paper from @vincentdebakker.bsky.social @jonbakerlab.bsky.social now published @natcomms.nature.com #MicroSky www.nature.com/articles/s41...
Reposted by Jaana Mannik
‘Chromosomal Topological Domain Formation Modulates Transcription and the Coupling of Neighboring Genes in Escherichia coli‘ by Drs. Nico Yehya, Christopher Bohrer, and collaborators, is now available on bioRxiv. Check it out! doi: doi.org/10.1101/2025...
Chromosomal Topological Domain Formation Modulates Transcription and the Coupling of Neighboring Genes in Escherichia coli
Chromosomal topology and transcription are tightly coupled, yet the quantitative impact of topological constraints on transcription, supercoiling, and the potential coupling between neighboring genes ...
doi.org
November 25, 2025 at 2:04 PM
‘Chromosomal Topological Domain Formation Modulates Transcription and the Coupling of Neighboring Genes in Escherichia coli‘ by Drs. Nico Yehya, Christopher Bohrer, and collaborators, is now available on bioRxiv. Check it out! doi: doi.org/10.1101/2025...
Reposted by Jaana Mannik
Research technologist position available in the Xiao lab: We are looking for a talented recent college graduate interested in learning how a single-molecule imaging lab operates to join our team. Check it out here: hiring.jhu.edu/careers?quer...
Research Technologist (Biophysics & Biological Chemistry) | Johns Hopkins University
119351 jobs in Johns Hopkins University
hiring.jhu.edu
November 25, 2025 at 2:08 PM
Research technologist position available in the Xiao lab: We are looking for a talented recent college graduate interested in learning how a single-molecule imaging lab operates to join our team. Check it out here: hiring.jhu.edu/careers?quer...
Reposted by Jaana Mannik
🆕 Vacancy! We are looking for an exceptional scientist with a research focus on nutrition and microbiome-based interventions for the prevention and management of obesity to join our Food, Microbiome and Health research programme.
💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J
💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J
November 24, 2025 at 10:00 AM
🆕 Vacancy! We are looking for an exceptional scientist with a research focus on nutrition and microbiome-based interventions for the prevention and management of obesity to join our Food, Microbiome and Health research programme.
💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J
💷 Competitive
🗓️ Apply by 18 January 2026
➡️ buff.ly/5CIkq6J
Reposted by Jaana Mannik
Reposted by Jaana Mannik
Extrusion- modulated DnaA activity
oscillations coordinate DNA replication
with biomass growth
doi.org/10.7554/eLif...
oscillations coordinate DNA replication
with biomass growth
doi.org/10.7554/eLif...
November 24, 2025 at 2:46 PM
Extrusion- modulated DnaA activity
oscillations coordinate DNA replication
with biomass growth
doi.org/10.7554/eLif...
oscillations coordinate DNA replication
with biomass growth
doi.org/10.7554/eLif...
Reposted by Jaana Mannik
An archaeal genetic code with all TAG codons as pyrrolysine www.science.org/doi/abs/10.1... #jcampubs
An archaeal genetic code with all TAG codons as pyrrolysine
Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...
www.science.org
November 21, 2025 at 4:20 PM
An archaeal genetic code with all TAG codons as pyrrolysine www.science.org/doi/abs/10.1... #jcampubs
Reposted by Jaana Mannik
Sharing this important article... for no reason whatsoever.
"We must also continue to deepen and refine our understanding of fundamental biological processes because these details frequently hold the keys to major advances in applied research."
elifesciences.org/articles/102...
"We must also continue to deepen and refine our understanding of fundamental biological processes because these details frequently hold the keys to major advances in applied research."
elifesciences.org/articles/102...
November 23, 2025 at 12:21 AM
Sharing this important article... for no reason whatsoever.
"We must also continue to deepen and refine our understanding of fundamental biological processes because these details frequently hold the keys to major advances in applied research."
elifesciences.org/articles/102...
"We must also continue to deepen and refine our understanding of fundamental biological processes because these details frequently hold the keys to major advances in applied research."
elifesciences.org/articles/102...
Reposted by Jaana Mannik
Faculty Position: Neurocomputation
Apply by December 1, 2025
WTI invites those from mathematical, computational, and related fields interested in working with experimentalists to develop new frameworks for understanding cognition.
🔗 wti.yale.edu/opportunities/faculty-neurocomputation
Apply by December 1, 2025
WTI invites those from mathematical, computational, and related fields interested in working with experimentalists to develop new frameworks for understanding cognition.
🔗 wti.yale.edu/opportunities/faculty-neurocomputation
November 17, 2025 at 3:37 PM
Faculty Position: Neurocomputation
Apply by December 1, 2025
WTI invites those from mathematical, computational, and related fields interested in working with experimentalists to develop new frameworks for understanding cognition.
🔗 wti.yale.edu/opportunities/faculty-neurocomputation
Apply by December 1, 2025
WTI invites those from mathematical, computational, and related fields interested in working with experimentalists to develop new frameworks for understanding cognition.
🔗 wti.yale.edu/opportunities/faculty-neurocomputation
Reposted by Jaana Mannik
Happy to share our most recent work www.pnas.org/doi/10.1073/.... Here we describe how efficient DNA replication in E. coli is dependent on an interaction between SSB-ssDNA and the DNA polymerase (Pol III). Thanks to all the co-authors for their hard work!
Genome integrity relies on rapid recycling of DNA Pol III in bacteria | PNAS
DNA replication requires precise coordination between DNA unwinding and DNA synthesis.
In all domains of life, protein–protein interactions at the ...
www.pnas.org
November 20, 2025 at 4:54 PM
Happy to share our most recent work www.pnas.org/doi/10.1073/.... Here we describe how efficient DNA replication in E. coli is dependent on an interaction between SSB-ssDNA and the DNA polymerase (Pol III). Thanks to all the co-authors for their hard work!
Reposted by Jaana Mannik
Bacterial networks #BacNet26 in September 2026 will be chaired by @lalouxlab.bsky.social and co-chaired by @s-lab.bsky.social with @coralietesseur.bsky.social
Sneak peak on invited speakers and preliminary program:
meetings.embo.org/event/26-bac...
Sneak peak on invited speakers and preliminary program:
meetings.embo.org/event/26-bac...
November 20, 2025 at 8:47 AM
Bacterial networks #BacNet26 in September 2026 will be chaired by @lalouxlab.bsky.social and co-chaired by @s-lab.bsky.social with @coralietesseur.bsky.social
Sneak peak on invited speakers and preliminary program:
meetings.embo.org/event/26-bac...
Sneak peak on invited speakers and preliminary program:
meetings.embo.org/event/26-bac...
Reposted by Jaana Mannik
Join us in Colorado next spring for the Keystone Symposia “Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection”. Registrations are now open! Details below ⬇️
Registration is now open for @keystonesymposia.bsky.social "Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection." Deadline for scholarships and abstract selected short talks is Jan 7! Join us this May for an amazing meeting! keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26
Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection | Keystone Symposia
Join us at the Keystone Symposia on Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection, May 2026, in Breckenridge, with field leaders!
keysym.us
November 19, 2025 at 5:59 PM
Join us in Colorado next spring for the Keystone Symposia “Beyond #Antibiotics: Emerging Strategies Combating #BacterialInfection”. Registrations are now open! Details below ⬇️
Reposted by Jaana Mannik
Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB https://www.biorxiv.org/content/10.1101/2025.11.19.689047v1
November 19, 2025 at 4:18 PM
Equipositioning of Chromosomes in the Polyploid Archaeon Haloferax volcanii by HpaAB https://www.biorxiv.org/content/10.1101/2025.11.19.689047v1
Reposted by Jaana Mannik
🚨Job claxon 🚨
University College Cork is looking to appoint a lecturer in Medical Microbiology into a permanent, non-clinical post
A great opportunity in a microbiology powerhouse
For details go to my.corehr.com/pls/uccrecru... and enter reference number 092153
University College Cork is looking to appoint a lecturer in Medical Microbiology into a permanent, non-clinical post
A great opportunity in a microbiology powerhouse
For details go to my.corehr.com/pls/uccrecru... and enter reference number 092153
University College Cork Vacancies
my.corehr.com
November 18, 2025 at 10:55 PM
🚨Job claxon 🚨
University College Cork is looking to appoint a lecturer in Medical Microbiology into a permanent, non-clinical post
A great opportunity in a microbiology powerhouse
For details go to my.corehr.com/pls/uccrecru... and enter reference number 092153
University College Cork is looking to appoint a lecturer in Medical Microbiology into a permanent, non-clinical post
A great opportunity in a microbiology powerhouse
For details go to my.corehr.com/pls/uccrecru... and enter reference number 092153
Reposted by Jaana Mannik
🎉We have announced a new professorship at the University of Gothenburg 🇸🇪 to celebrate our Crown Princess’s 50th birthday!
🌿Broad focus on biodiversity — from microbes to modelling
📢A fantastic opportunity for researchers working across scales and disciplines!
🔗 web103.reachmee.com/ext/I005/103...
🌿Broad focus on biodiversity — from microbes to modelling
📢A fantastic opportunity for researchers working across scales and disciplines!
🔗 web103.reachmee.com/ext/I005/103...
The Crown Princess Victoria Professorship in Biodiversity
Professorship in Biodiversity.
The University of Gothenburg hereby announces a unique and prestigious position – the
web103.reachmee.com
October 3, 2025 at 5:29 AM
🎉We have announced a new professorship at the University of Gothenburg 🇸🇪 to celebrate our Crown Princess’s 50th birthday!
🌿Broad focus on biodiversity — from microbes to modelling
📢A fantastic opportunity for researchers working across scales and disciplines!
🔗 web103.reachmee.com/ext/I005/103...
🌿Broad focus on biodiversity — from microbes to modelling
📢A fantastic opportunity for researchers working across scales and disciplines!
🔗 web103.reachmee.com/ext/I005/103...