Jaana Mannik
@jaanamannik.bsky.social
Cell & molecular biologist. Biophysics research @Univ. of Tennessee, Knoxville.
volweb.utk.edu/~jmannik/
Unraveling the self-assembly process of cell division machinery in E. coli.
volweb.utk.edu/~jmannik/
Unraveling the self-assembly process of cell division machinery in E. coli.
Reposted by Jaana Mannik
Core elements play distinct roles in promoter birth and transcriptional regulation | bioRxiv share.google/ASRbyWVuJdNz...
Core elements play distinct roles in promoter birth and transcriptional regulation
Gene expression shapes phenotypes and evolution. However, studies of gene regulation focus on transcription factors, overlooking core promoters. To investigate how promoters emerge and regulate transc...
share.google
December 7, 2025 at 4:09 PM
Core elements play distinct roles in promoter birth and transcriptional regulation | bioRxiv share.google/ASRbyWVuJdNz...
Reposted by Jaana Mannik
Archaeal histone HTkC hypercompacts DNA https://www.biorxiv.org/content/10.64898/2025.12.06.692711v1
December 7, 2025 at 8:29 AM
Reposted by Jaana Mannik
Biological Theory is now on Bluesky!
We have a new team of editors and a new editorial board.
We will soon be posting about all our articles.
Find out more about the journal at link.springer.com/journal/13752
We have a new team of editors and a new editorial board.
We will soon be posting about all our articles.
Find out more about the journal at link.springer.com/journal/13752
December 3, 2025 at 11:51 AM
Biological Theory is now on Bluesky!
We have a new team of editors and a new editorial board.
We will soon be posting about all our articles.
Find out more about the journal at link.springer.com/journal/13752
We have a new team of editors and a new editorial board.
We will soon be posting about all our articles.
Find out more about the journal at link.springer.com/journal/13752
Reposted by Jaana Mannik
Opening of a Group Leader position in AI in genomics at Institut Pasteur @pasteur.fr , Paris research.pasteur.fr/en/call/mid-...
Mid-career Group Leader position in AI in genomics at Institut Pasteur, Paris - Research
Institut Pasteur and the CNRS are launching a call for a mid-career group leader position in AI in genomics. We are looking for an experienced researcher (typically with > 8 years of research experien...
research.pasteur.fr
December 6, 2025 at 9:49 AM
Opening of a Group Leader position in AI in genomics at Institut Pasteur @pasteur.fr , Paris research.pasteur.fr/en/call/mid-...
Reposted by Jaana Mannik
We’re hiring!
The Department of Physics
@sfuphysics.bsky.social
at Simon Fraser U (in beautiful and vibrant Vancouver) seeks applications for an Assistant or Associate Professor in Experimental Biophysics, encompassing all scales of life from molecules to ecosystems.
@sfuscience.bsky.social
The Department of Physics
@sfuphysics.bsky.social
at Simon Fraser U (in beautiful and vibrant Vancouver) seeks applications for an Assistant or Associate Professor in Experimental Biophysics, encompassing all scales of life from molecules to ecosystems.
@sfuscience.bsky.social
December 5, 2025 at 5:54 PM
We’re hiring!
The Department of Physics
@sfuphysics.bsky.social
at Simon Fraser U (in beautiful and vibrant Vancouver) seeks applications for an Assistant or Associate Professor in Experimental Biophysics, encompassing all scales of life from molecules to ecosystems.
@sfuscience.bsky.social
The Department of Physics
@sfuphysics.bsky.social
at Simon Fraser U (in beautiful and vibrant Vancouver) seeks applications for an Assistant or Associate Professor in Experimental Biophysics, encompassing all scales of life from molecules to ecosystems.
@sfuscience.bsky.social
Reposted by Jaana Mannik
Our paper on polymyxin interacting with the E. coli outer membrane is out! Simulations by the very talented @dheerajprakaash.bsky.social www.nature.com/articles/s42...
To scale outer membrane protein island simulated at coarse-grained resolution with portions refined at all atom resolution.
To scale outer membrane protein island simulated at coarse-grained resolution with portions refined at all atom resolution.
Polymyxins slow down lateral diffusion of proteins and lipopolysaccharide in the E. coli outer membrane - Communications Biology
Multi-scale molecular dynamics simulations reveal that polymyxins form polymyxin-protein aggregates upon associating with the E. coli outer membrane thereby reducing lateral mobility of outer membrane...
www.nature.com
December 5, 2025 at 3:42 PM
Our paper on polymyxin interacting with the E. coli outer membrane is out! Simulations by the very talented @dheerajprakaash.bsky.social www.nature.com/articles/s42...
To scale outer membrane protein island simulated at coarse-grained resolution with portions refined at all atom resolution.
To scale outer membrane protein island simulated at coarse-grained resolution with portions refined at all atom resolution.
Reposted by Jaana Mannik
My department at California State University Northridge is hiring! We're looking for a new colleague studying microbiology or molecular/cellular biology. I'm not on the search committee, but happy to answer questions about the department and campus, and life in LA
buff.ly/Pc1KOaC
buff.ly/Pc1KOaC
Career Opportunities
Applicant Log-In
careers.pageuppeople.com
December 4, 2025 at 7:19 PM
My department at California State University Northridge is hiring! We're looking for a new colleague studying microbiology or molecular/cellular biology. I'm not on the search committee, but happy to answer questions about the department and campus, and life in LA
buff.ly/Pc1KOaC
buff.ly/Pc1KOaC
Reposted by Jaana Mannik
@science.org 🧬🔬 Multiscale structure of #chromatin condensates explains phase separation and material properties | Science www.science.org/doi/10.1126/... @janhuemar.bsky.social et al.
Multiscale structure of chromatin condensates explains phase separation and material properties
The structure and interaction networks of molecules within biomolecular condensates are poorly understood. Using cryo–electron tomography and molecular dynamics simulations, we elucidated the structur...
www.science.org
December 5, 2025 at 5:24 AM
@science.org 🧬🔬 Multiscale structure of #chromatin condensates explains phase separation and material properties | Science www.science.org/doi/10.1126/... @janhuemar.bsky.social et al.
Reposted by Jaana Mannik
Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB @ascbiology.bsky.social in Philadelphia. Just drop me a line.
December 4, 2025 at 8:42 AM
Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB @ascbiology.bsky.social in Philadelphia. Just drop me a line.
Reposted by Jaana Mannik
Now published. Thank you very much to our collaborative team, and very supportive editors and reviewers!!!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation | PNAS
Nucleotide triphosphate (NTP)-dependent molecular switches regulate essential cellular
processes by cycling between active and inactive states thro...
www.pnas.org
December 4, 2025 at 7:23 PM
Now published. Thank you very much to our collaborative team, and very supportive editors and reviewers!!!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by Jaana Mannik
Reposted by Jaana Mannik
JB Editor's Choice: Anderson, Khursigara et al. review the role of peptidoglycomics in understanding the structure and function of peptidoglycan.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
December 2, 2025 at 8:54 PM
JB Editor's Choice: Anderson, Khursigara et al. review the role of peptidoglycomics in understanding the structure and function of peptidoglycan.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
Reposted by Jaana Mannik
December 3, 2025 at 3:53 PM
Reposted by Jaana Mannik
Would you like to work with us?
At JAMSTEC, we are recruiting postdoctoral researchers through the Young Research Fellow program.
This program allows fellows to independently pursue their own research projects.
www.jamstec.go.jp/recruit/e/jy...
At JAMSTEC, we are recruiting postdoctoral researchers through the Young Research Fellow program.
This program allows fellows to independently pursue their own research projects.
www.jamstec.go.jp/recruit/e/jy...
JAMSTEC Young Research Fellow (JYRF) | JAMSTEC - JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY
JAMSTEC Young Research Fellow (JYRF)
www.jamstec.go.jp
June 4, 2025 at 7:38 AM
Would you like to work with us?
At JAMSTEC, we are recruiting postdoctoral researchers through the Young Research Fellow program.
This program allows fellows to independently pursue their own research projects.
www.jamstec.go.jp/recruit/e/jy...
At JAMSTEC, we are recruiting postdoctoral researchers through the Young Research Fellow program.
This program allows fellows to independently pursue their own research projects.
www.jamstec.go.jp/recruit/e/jy...
Reposted by Jaana Mannik
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Development's Pathway to Independence Programme
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...
www.biologists.com
December 3, 2025 at 6:56 AM
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Reposted by Jaana Mannik
New York Times article on science funding with some depressing but familiar curves with interactive graphics.
www.nytimes.com/interactive/...
www.nytimes.com/interactive/...
The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine (Gift Article)
A quiet policy change means the government is making fewer bets on long-term science.
www.nytimes.com
December 2, 2025 at 11:57 AM
New York Times article on science funding with some depressing but familiar curves with interactive graphics.
www.nytimes.com/interactive/...
www.nytimes.com/interactive/...
Reposted by Jaana Mannik
🚨Job Alert plz RT!
Johns Hopkins Psych & Brain Sciences is looking for a new colleague using behavioral or computational approaches to study cognition!
We are excited about many areas of (esp higher) cognition in human adults, children, or nonhuman animals
Open-rank
apply.interfolio.com/178146
Johns Hopkins Psych & Brain Sciences is looking for a new colleague using behavioral or computational approaches to study cognition!
We are excited about many areas of (esp higher) cognition in human adults, children, or nonhuman animals
Open-rank
apply.interfolio.com/178146
December 2, 2025 at 2:54 AM
🚨Job Alert plz RT!
Johns Hopkins Psych & Brain Sciences is looking for a new colleague using behavioral or computational approaches to study cognition!
We are excited about many areas of (esp higher) cognition in human adults, children, or nonhuman animals
Open-rank
apply.interfolio.com/178146
Johns Hopkins Psych & Brain Sciences is looking for a new colleague using behavioral or computational approaches to study cognition!
We are excited about many areas of (esp higher) cognition in human adults, children, or nonhuman animals
Open-rank
apply.interfolio.com/178146
Reposted by Jaana Mannik
Reposted by Jaana Mannik
December 1, 2025 at 5:36 PM
Reposted by Jaana Mannik
📢Our MD simulation is out in Biophysical Journal!
The nonequilibrium polysome dynamics expands bacterial nucleoids and helps separate daughter chromosomes. Results agree with our previous experiments and extend our earlier model.
authors.elsevier.com/a/1mBGt_9FM7...
#Microbiology #Biophysics
The nonequilibrium polysome dynamics expands bacterial nucleoids and helps separate daughter chromosomes. Results agree with our previous experiments and extend our earlier model.
authors.elsevier.com/a/1mBGt_9FM7...
#Microbiology #Biophysics
November 30, 2025 at 5:26 PM
📢Our MD simulation is out in Biophysical Journal!
The nonequilibrium polysome dynamics expands bacterial nucleoids and helps separate daughter chromosomes. Results agree with our previous experiments and extend our earlier model.
authors.elsevier.com/a/1mBGt_9FM7...
#Microbiology #Biophysics
The nonequilibrium polysome dynamics expands bacterial nucleoids and helps separate daughter chromosomes. Results agree with our previous experiments and extend our earlier model.
authors.elsevier.com/a/1mBGt_9FM7...
#Microbiology #Biophysics
📢Our MD simulation is out in Biophysical Journal!
The nonequilibrium polysome dynamics expands bacterial nucleoids and helps separate daughter chromosomes. Results agree with our previous experiments and extend our earlier model.
authors.elsevier.com/a/1mBGt_9FM7...
#Microbiology #Biophysics
The nonequilibrium polysome dynamics expands bacterial nucleoids and helps separate daughter chromosomes. Results agree with our previous experiments and extend our earlier model.
authors.elsevier.com/a/1mBGt_9FM7...
#Microbiology #Biophysics
November 30, 2025 at 6:01 PM
Reposted by Jaana Mannik
To all trainees interested in channels and transporters: the joint FEBS/EMBO course will go ahead in Erice, Italy from May 13-19 2026:
network.febs.org/posts/new-jo...
Further details to come soon.
Please share and repost.
network.febs.org/posts/new-jo...
Further details to come soon.
Please share and repost.
November 26, 2025 at 4:17 PM
To all trainees interested in channels and transporters: the joint FEBS/EMBO course will go ahead in Erice, Italy from May 13-19 2026:
network.febs.org/posts/new-jo...
Further details to come soon.
Please share and repost.
network.febs.org/posts/new-jo...
Further details to come soon.
Please share and repost.
Reposted by Jaana Mannik
Let’s wrap things up: Open and closed hypernucleosomes in Asgard archaea
Let’s wrap things up: Open and closed hypernucleosomes in Asgard archaea
Asgard archaea are widely considered the closest living relatives of eukaryotes. In this issue of Molecular Cell, Ranawat et al. report high-resolution structures of hypernucleosomes formed by the hodarchaeal HHoB histone, disclosing open and closed chromatin conformations.
dlvr.it
November 26, 2025 at 8:14 PM
Let’s wrap things up: Open and closed hypernucleosomes in Asgard archaea
Reposted by Jaana Mannik
Happy to share a new preprint from the lab: Marko became interested in whether the disordered linker of FtsZ might influence how the protein organizes into the Z-ring. And this led to some surprising findings!
Preprint: www.biorxiv.org/content/10.1...
Preprint: www.biorxiv.org/content/10.1...
Charge segregation in the C-terminal linker of FtsZ enables Z-ring scaling with prokaryotic cell width
Bacterial cytokinesis is orchestrated by the Z-ring, a cytoskeletal structure formed by treadmilling filaments of the tubulin-like GTPase FtsZ. During assembly, filament curvature must match the cell ...
www.biorxiv.org
November 26, 2025 at 9:29 PM
Happy to share a new preprint from the lab: Marko became interested in whether the disordered linker of FtsZ might influence how the protein organizes into the Z-ring. And this led to some surprising findings!
Preprint: www.biorxiv.org/content/10.1...
Preprint: www.biorxiv.org/content/10.1...
Reposted by Jaana Mannik
We are hiring a 2-year postdoctoral researcher to join our Membrane Biophysics team at the CBS in Montpellier. Join us to reinvent Atomic Force Microscopy to image the most common interface on our planet: the surface of water @membranesbiophy.bsky.social @cbsmontpellier.bsky.social
November 25, 2025 at 1:04 PM
We are hiring a 2-year postdoctoral researcher to join our Membrane Biophysics team at the CBS in Montpellier. Join us to reinvent Atomic Force Microscopy to image the most common interface on our planet: the surface of water @membranesbiophy.bsky.social @cbsmontpellier.bsky.social