Pinned
Inhibitory inputs from thalamus promote resilient spiking in tail of striatum
Neuroscience; Sensory neuroscience
www.cell.com
Latest from the lab: Laura Haetzel finds that excitatory transmission from auditory thalamus to tail of striatum is accompanied by a sparse inhibitory projection. This allows for state-dependent control of striatal output.
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Reposted by Jan Gründemann
Join us for BonnBrain 2026!
The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline.
Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!
The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline.
Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!
November 26, 2025 at 3:25 PM
Join us for BonnBrain 2026!
The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline.
Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!
The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline.
Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!
Reposted by Jan Gründemann
Memory traces bias new learning for hippocampal generalization https://www.biorxiv.org/content/10.1101/2025.11.24.690297v1
November 26, 2025 at 7:15 AM
Memory traces bias new learning for hippocampal generalization https://www.biorxiv.org/content/10.1101/2025.11.24.690297v1
Reposted by Jan Gründemann
✨ New preprint ✨ What if we could watch AND control thousands of individual neurons in behaving mice—with stable access over months? 🧠⚡ Our work introduces transgenic all-optical tools that make this possible - and a resulting surprising discovery! 🔭💡
www.biorxiv.org/content/10.1... 1/13 🧵
www.biorxiv.org/content/10.1... 1/13 🧵
Large-scale cellular-resolution read/write of activity enables discovery of cell types defined by complex circuit properties
The complexity of the mammalian brain’s vast population of interconnected neurons poses a formidable challenge to elucidate its underlying mechanisms of coordination and computation. A key step forwar...
www.biorxiv.org
November 13, 2025 at 12:24 AM
✨ New preprint ✨ What if we could watch AND control thousands of individual neurons in behaving mice—with stable access over months? 🧠⚡ Our work introduces transgenic all-optical tools that make this possible - and a resulting surprising discovery! 🔭💡
www.biorxiv.org/content/10.1... 1/13 🧵
www.biorxiv.org/content/10.1... 1/13 🧵
Reposted by Jan Gründemann
Out now: Favila, Capece Marsico et al. 2025, Nature Communications: Using longitudinal deep-brain imaging, we report that amygdala interneurons exhibit complex and heterogeneous plasticity during associative learning, at both the single-cell and population level.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
Heterogeneous plasticity of amygdala interneurons in associative learning and extinction - Nature Communications
In this study, the authors uncover how diverse inhibitory interneurons in the amygdala flexibly contribute to fear and safety learning, revealing a key role for inhibition in emotional memory and adap...
www.nature.com
November 12, 2025 at 6:55 PM
Out now: Favila, Capece Marsico et al. 2025, Nature Communications: Using longitudinal deep-brain imaging, we report that amygdala interneurons exhibit complex and heterogeneous plasticity during associative learning, at both the single-cell and population level.
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
Reposted by Jan Gründemann
Come to #Bonn next March and join the #BonnBrain Conference 2026! There’s still time left to register and submit your abstract:
🌍 https://bonnbrain.de/ @bonnbrainconf.bsky.social
⏰ March 23–25, 2026
📍 @dzne.science #DZNE
🌍 https://bonnbrain.de/ @bonnbrainconf.bsky.social
⏰ March 23–25, 2026
📍 @dzne.science #DZNE
November 12, 2025 at 4:20 AM
Come to #Bonn next March and join the #BonnBrain Conference 2026! There’s still time left to register and submit your abstract:
🌍 https://bonnbrain.de/ @bonnbrainconf.bsky.social
⏰ March 23–25, 2026
📍 @dzne.science #DZNE
🌍 https://bonnbrain.de/ @bonnbrainconf.bsky.social
⏰ March 23–25, 2026
📍 @dzne.science #DZNE
Reposted by Jan Gründemann
Learning-dependent cholinergic plasticity reconfigures cortical circuit dynamics. https://www.biorxiv.org/content/10.1101/2025.11.10.687664v1
November 11, 2025 at 4:15 PM
Learning-dependent cholinergic plasticity reconfigures cortical circuit dynamics. https://www.biorxiv.org/content/10.1101/2025.11.10.687664v1
Latest from the lab: Laura Haetzel finds that excitatory transmission from auditory thalamus to tail of striatum is accompanied by a sparse inhibitory projection. This allows for state-dependent control of striatal output.
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Inhibitory inputs from thalamus promote resilient spiking in tail of striatum
Neuroscience; Sensory neuroscience
www.cell.com
November 11, 2025 at 3:04 PM
Latest from the lab: Laura Haetzel finds that excitatory transmission from auditory thalamus to tail of striatum is accompanied by a sparse inhibitory projection. This allows for state-dependent control of striatal output.
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Reposted by Jan Gründemann
Next-generation enhancer AAVs for selective interspecies targeting of midbrain dopaminergic neurons https://www.biorxiv.org/content/10.1101/2025.11.06.687071v1
November 8, 2025 at 7:15 AM
Next-generation enhancer AAVs for selective interspecies targeting of midbrain dopaminergic neurons https://www.biorxiv.org/content/10.1101/2025.11.06.687071v1
Reposted by Jan Gründemann
Plateau potentials are instructive signals for behavioral timescale synaptic plasticity in the neocortex https://www.biorxiv.org/content/10.1101/2025.11.07.687250v1
November 8, 2025 at 8:15 AM
Plateau potentials are instructive signals for behavioral timescale synaptic plasticity in the neocortex https://www.biorxiv.org/content/10.1101/2025.11.07.687250v1
Reposted by Jan Gründemann
How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )
VTA dopamine neuron activity produces spatially organized value representations https://www.biorxiv.org/content/10.1101/2025.11.04.685995v1
November 7, 2025 at 8:46 PM
How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )
Reposted by Jan Gründemann
Sickness engrams modulate anticipatory immune responses https://www.biorxiv.org/content/10.1101/2025.11.03.686140v1
November 5, 2025 at 4:15 PM
Sickness engrams modulate anticipatory immune responses https://www.biorxiv.org/content/10.1101/2025.11.03.686140v1
Reposted by Jan Gründemann
Ephaptic-Axonal Interactions Shape Radial Biases DuringNeural Self-Organization https://www.biorxiv.org/content/10.1101/2025.11.03.686361v1
November 5, 2025 at 4:16 PM
Ephaptic-Axonal Interactions Shape Radial Biases DuringNeural Self-Organization https://www.biorxiv.org/content/10.1101/2025.11.03.686361v1
Reposted by Jan Gründemann
Such a nice collection of brain-body interaction articles in the special issue of @currentbiology.bsky.social. Love the beautiful vagus nerve on the cover by Andreas Vesalius www.cell.com/current-biol...
October 22, 2025 at 6:44 PM
Such a nice collection of brain-body interaction articles in the special issue of @currentbiology.bsky.social. Love the beautiful vagus nerve on the cover by Andreas Vesalius www.cell.com/current-biol...
Reposted by Jan Gründemann
We are hiring 🎉 Brandeis Neuroscience is looking for an Assistant Professor. The search is in the broad area of cellular/circuit neuroscience. It’s a fantastic place to do research and train students.If you’re interested, apply and reach out with any questions!
academicjobsonline.org/ajo/jobs/30961
academicjobsonline.org/ajo/jobs/30961
Brandeis University, Biology Department
Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US
academicjobsonline.org
October 22, 2025 at 11:57 PM
We are hiring 🎉 Brandeis Neuroscience is looking for an Assistant Professor. The search is in the broad area of cellular/circuit neuroscience. It’s a fantastic place to do research and train students.If you’re interested, apply and reach out with any questions!
academicjobsonline.org/ajo/jobs/30961
academicjobsonline.org/ajo/jobs/30961
Reposted by Jan Gründemann
I am thrilled to share our latest work: we identified a population of central amygdala neurons that promote the earliest and perhaps most important social behavior: pup suckling!... We also developed new tools for pup neuroscience
Work by @Jeff Moore now at USC, a collaboration with @Sam Pfaff lab
Work by @Jeff Moore now at USC, a collaboration with @Sam Pfaff lab
October 21, 2025 at 10:18 AM
I am thrilled to share our latest work: we identified a population of central amygdala neurons that promote the earliest and perhaps most important social behavior: pup suckling!... We also developed new tools for pup neuroscience
Work by @Jeff Moore now at USC, a collaboration with @Sam Pfaff lab
Work by @Jeff Moore now at USC, a collaboration with @Sam Pfaff lab
Reposted by Jan Gründemann
Selective coupling and decoupling coordinate distributed brain networks for precise action https://www.biorxiv.org/content/10.1101/2025.10.19.683309v1
October 20, 2025 at 6:15 PM
Selective coupling and decoupling coordinate distributed brain networks for precise action https://www.biorxiv.org/content/10.1101/2025.10.19.683309v1
Reposted by Jan Gründemann
Registration open: eveeno.com/applicationb...
Under the theme “From Genes to Circuits and Behavior”, top neuroscientists - incl. Cori Bargmann, @edvardmoser.bsky.social, Rosa Paolicelli, Maude Baldwin & Zachary Knight - will meet at to explore how neural circuits drive behavior.
Under the theme “From Genes to Circuits and Behavior”, top neuroscientists - incl. Cori Bargmann, @edvardmoser.bsky.social, Rosa Paolicelli, Maude Baldwin & Zachary Knight - will meet at to explore how neural circuits drive behavior.
October 20, 2025 at 12:53 PM
Registration open: eveeno.com/applicationb...
Under the theme “From Genes to Circuits and Behavior”, top neuroscientists - incl. Cori Bargmann, @edvardmoser.bsky.social, Rosa Paolicelli, Maude Baldwin & Zachary Knight - will meet at to explore how neural circuits drive behavior.
Under the theme “From Genes to Circuits and Behavior”, top neuroscientists - incl. Cori Bargmann, @edvardmoser.bsky.social, Rosa Paolicelli, Maude Baldwin & Zachary Knight - will meet at to explore how neural circuits drive behavior.
Reposted by Jan Gründemann
Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41.... New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8
October 15, 2025 at 4:11 PM
Just out in Nature! “The astrocytic ensemble acts as a multiday trace to stabilize memory.” We identified astrocytic ensembles that link experiences across days to stabilize memory nature.com/articles/s41.... New astrocyte tools are openly available at Addgene: addgene.org/Jun_Nagai/. 1/8
Reposted by Jan Gründemann
I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island.
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
October 16, 2025 at 6:04 PM
I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island.
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
Reposted by Jan Gründemann
Impact of serotonin transporter deficiency on parvalbumin- and neuropeptide Y-producing interneurons of the basolateral amygdala https://www.biorxiv.org/content/10.1101/2025.10.07.680627v1
October 7, 2025 at 9:17 PM
Impact of serotonin transporter deficiency on parvalbumin- and neuropeptide Y-producing interneurons of the basolateral amygdala https://www.biorxiv.org/content/10.1101/2025.10.07.680627v1
Reposted by Jan Gründemann
👀“experience of a punished outcome generates a BLA representation that is selectively replayed when animals subsequently abort choice of the large/risky reward option.”
⚡️“… risk leads to the incorporation of newly encoding BLA neurons into the pre-choice representation”
⚡️“… risk leads to the incorporation of newly encoding BLA neurons into the pre-choice representation”
Risk reshapes amygdala representation of choice https://www.biorxiv.org/content/10.1101/2025.10.06.680813v1
October 8, 2025 at 12:14 AM
👀“experience of a punished outcome generates a BLA representation that is selectively replayed when animals subsequently abort choice of the large/risky reward option.”
⚡️“… risk leads to the incorporation of newly encoding BLA neurons into the pre-choice representation”
⚡️“… risk leads to the incorporation of newly encoding BLA neurons into the pre-choice representation”
Reposted by Jan Gründemann
🔬 Join us for the next iBehave Seminar Series 2025 lecture with Prof. Dr. Mark Schnitzer @Stanford on Oct 9, 11:00 DZNE Bonn. Host: @jangrundemann.bsky.social
Title: Cell-type specific voltage imaging of neural spiking, oscillations, waves, and memory dynamics
📧 Zoom info: [email protected]
Title: Cell-type specific voltage imaging of neural spiking, oscillations, waves, and memory dynamics
📧 Zoom info: [email protected]
October 6, 2025 at 3:55 PM
🔬 Join us for the next iBehave Seminar Series 2025 lecture with Prof. Dr. Mark Schnitzer @Stanford on Oct 9, 11:00 DZNE Bonn. Host: @jangrundemann.bsky.social
Title: Cell-type specific voltage imaging of neural spiking, oscillations, waves, and memory dynamics
📧 Zoom info: [email protected]
Title: Cell-type specific voltage imaging of neural spiking, oscillations, waves, and memory dynamics
📧 Zoom info: [email protected]
Sensory origin of visually evoked activity in auditory cortex
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Sensory origin of visually evoked activity in auditory cortex
Sound-evoked face movements in mice largely account for sound-driven activity in visual
cortex. Yet visual stimuli rarely trigger face movements, and such movements fail
to explain visually evoked res...
www.cell.com
October 5, 2025 at 10:06 AM
Sensory origin of visually evoked activity in auditory cortex
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Jan Gründemann
Travel awards are available for undergraduate students looking to attend #Cosyne25! The application is short, and the deadline is Nov 12. @cosynemeeting.bsky.social
Application: shorturl.at/6NEyk
More info: www.cosyne.org/travel-grants
(1/2)
Application: shorturl.at/6NEyk
More info: www.cosyne.org/travel-grants
(1/2)
Travel Grants — COSYNE
Apply for COSYNE 2026 Travel Grants to support your participation in Lisbon and Cascais, Portugal. Grants are available for students, postdocs, and PIs, including programs for Childcare, Presenters, N...
www.cosyne.org
October 3, 2025 at 3:10 PM
Travel awards are available for undergraduate students looking to attend #Cosyne25! The application is short, and the deadline is Nov 12. @cosynemeeting.bsky.social
Application: shorturl.at/6NEyk
More info: www.cosyne.org/travel-grants
(1/2)
Application: shorturl.at/6NEyk
More info: www.cosyne.org/travel-grants
(1/2)
Reposted by Jan Gründemann
A couple of new preprints out from Kash Lab!
October 3, 2025 at 4:40 PM
A couple of new preprints out from Kash Lab!