Rui Gonçalo Martinho
@martinholab.bsky.social
Our AIM is to understand the way germ cells segregate from the soma and differentiate into functional gametes.
Reposted by Rui Gonçalo Martinho
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
November 14, 2025 at 4:08 PM
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
Reposted by Rui Gonçalo Martinho
TT faculty job opening in #Neuroscience!
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
Brandeis University, Biology Department
Job #AJO30961, Assistant Professor in Biology and Neuroscience Program, Biology Department, Brandeis University, Waltham, Massachusetts, US
academicjobsonline.org
October 22, 2025 at 11:28 PM
TT faculty job opening in #Neuroscience!
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
We are looking for a colleague to join us in our fantastic Biology Department and Neuroscience Program at Brandeis. We are a group of *very* collaborative, supportive, and productive scientists (& humans!) so please apply
academicjobsonline.org/ajo/jobs/30961
Reposted by Rui Gonçalo Martinho
🪰 A new ‘Eyemap’ developed by a team led by Arthur Zhao & @michaelreiser.bsky.social reveals how visual information detected by the fly’s eye shows up in neurons deep in the brain. Remarkably, the eye’s shape determines how flies see motion.👁️
🔗 hhmi.news/4kSZjou
🔗 hhmi.news/4kSZjou
July 23, 2025 at 3:18 PM
🪰 A new ‘Eyemap’ developed by a team led by Arthur Zhao & @michaelreiser.bsky.social reveals how visual information detected by the fly’s eye shows up in neurons deep in the brain. Remarkably, the eye’s shape determines how flies see motion.👁️
🔗 hhmi.news/4kSZjou
🔗 hhmi.news/4kSZjou
Most migratory birds are gone but its still a gorgeous place do visit - Boquilobo Bog Natural Reserve.
November 9, 2025 at 11:45 AM
Most migratory birds are gone but its still a gorgeous place do visit - Boquilobo Bog Natural Reserve.
Reposted by Rui Gonçalo Martinho
Not today, parasitic #wasps!✋🚫
#Stinkbugs use a fungus-carrying organ on their hind legs to coat their eggs in #fungi🍄🦵
This provides a physical defense against #parasitic wasp oviposition🛡️
www.science.org/doi/10.1126/...
#Stinkbugs use a fungus-carrying organ on their hind legs to coat their eggs in #fungi🍄🦵
This provides a physical defense against #parasitic wasp oviposition🛡️
www.science.org/doi/10.1126/...
October 22, 2025 at 5:12 PM
Not today, parasitic #wasps!✋🚫
#Stinkbugs use a fungus-carrying organ on their hind legs to coat their eggs in #fungi🍄🦵
This provides a physical defense against #parasitic wasp oviposition🛡️
www.science.org/doi/10.1126/...
#Stinkbugs use a fungus-carrying organ on their hind legs to coat their eggs in #fungi🍄🦵
This provides a physical defense against #parasitic wasp oviposition🛡️
www.science.org/doi/10.1126/...
Reposted by Rui Gonçalo Martinho
Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...
October 6, 2025 at 6:09 PM
Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...
Reposted by Rui Gonçalo Martinho
Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...
October 2, 2025 at 2:24 PM
Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...
Reposted by Rui Gonçalo Martinho
#FossilFriday ‘Black Beauty’, one of the smallest-known specimens of Tyrannosaurus rex, displayed at The Royal Tyrell Museum in Calgary, Alberta.
wp.me/p3ihHu-1MX
wp.me/p3ihHu-1MX
October 3, 2025 at 9:51 PM
#FossilFriday ‘Black Beauty’, one of the smallest-known specimens of Tyrannosaurus rex, displayed at The Royal Tyrell Museum in Calgary, Alberta.
wp.me/p3ihHu-1MX
wp.me/p3ihHu-1MX
Quick Drosophila question: I’m planning to integrate a construct on the second chromosome but would like to avoid the attP40 landing site. Any suggestion for a good alternative attP site on chromosome II? It’s for a skeletal-muscle–related project.
Thanks! 🙂
Rui
Thanks! 🙂
Rui
September 30, 2025 at 6:34 PM
Quick Drosophila question: I’m planning to integrate a construct on the second chromosome but would like to avoid the attP40 landing site. Any suggestion for a good alternative attP site on chromosome II? It’s for a skeletal-muscle–related project.
Thanks! 🙂
Rui
Thanks! 🙂
Rui
Reposted by Rui Gonçalo Martinho
Our latest issue is out!👇
www.cell.com/current-biol...
On the cover: Nautilus ≈ 🐙+🐚
(Maybe — like the Nautilus — our journal is a living fossil, believing in the interest and inspiration our readers might draw from the diversity of biological systems, questions and approaches we try to feature🙏 )
www.cell.com/current-biol...
On the cover: Nautilus ≈ 🐙+🐚
(Maybe — like the Nautilus — our journal is a living fossil, believing in the interest and inspiration our readers might draw from the diversity of biological systems, questions and approaches we try to feature🙏 )
September 22, 2025 at 5:28 PM
Our latest issue is out!👇
www.cell.com/current-biol...
On the cover: Nautilus ≈ 🐙+🐚
(Maybe — like the Nautilus — our journal is a living fossil, believing in the interest and inspiration our readers might draw from the diversity of biological systems, questions and approaches we try to feature🙏 )
www.cell.com/current-biol...
On the cover: Nautilus ≈ 🐙+🐚
(Maybe — like the Nautilus — our journal is a living fossil, believing in the interest and inspiration our readers might draw from the diversity of biological systems, questions and approaches we try to feature🙏 )
Reposted by Rui Gonçalo Martinho
Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...
Epigenetic relay: Polycomb-directed DNA methylation in mammalian development
In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...
journals.plos.org
September 15, 2025 at 7:04 PM
Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...
Reposted by Rui Gonçalo Martinho
Chart from last year... No big change in % of US applicants, or? . marie-sklodowska-curie-actions.ec.europa.eu/news/msca-po...
September 14, 2025 at 1:50 PM
Chart from last year... No big change in % of US applicants, or? . marie-sklodowska-curie-actions.ec.europa.eu/news/msca-po...
Reposted by Rui Gonçalo Martinho
📰 New paper alert!
In a collaborative project with the lab of Clemens Plaschka at the IMP, the lab of Julius Brennecke has revealed how PIWI proteins kickstart transposon silencing in reproductive cells.
The findings are published in Molecular Cell: www.sciencedirect.com/science/arti...
In a collaborative project with the lab of Clemens Plaschka at the IMP, the lab of Julius Brennecke has revealed how PIWI proteins kickstart transposon silencing in reproductive cells.
The findings are published in Molecular Cell: www.sciencedirect.com/science/arti...
How cells lock down “jumping genes”:
Researchers from IMBA and IMP identify the first protein interactions that trigger PIWI–piRNA–mediated transposon silencing, using AlphaFold predictions, genetics, biochemistry and cell biology.
Read more: www.viennabiocenter.org/about/news/t...
Researchers from IMBA and IMP identify the first protein interactions that trigger PIWI–piRNA–mediated transposon silencing, using AlphaFold predictions, genetics, biochemistry and cell biology.
Read more: www.viennabiocenter.org/about/news/t...
September 9, 2025 at 8:57 AM
📰 New paper alert!
In a collaborative project with the lab of Clemens Plaschka at the IMP, the lab of Julius Brennecke has revealed how PIWI proteins kickstart transposon silencing in reproductive cells.
The findings are published in Molecular Cell: www.sciencedirect.com/science/arti...
In a collaborative project with the lab of Clemens Plaschka at the IMP, the lab of Julius Brennecke has revealed how PIWI proteins kickstart transposon silencing in reproductive cells.
The findings are published in Molecular Cell: www.sciencedirect.com/science/arti...
Reposted by Rui Gonçalo Martinho
Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪
September 13, 2025 at 1:13 AM
Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪
Reposted by Rui Gonçalo Martinho
Reposted by Rui Gonçalo Martinho
I hope everyone on the other side of the Earth is enjoying the total lunar eclipse! Except for flat Earthers.
September 7, 2025 at 6:18 PM
I hope everyone on the other side of the Earth is enjoying the total lunar eclipse! Except for flat Earthers.
Reposted by Rui Gonçalo Martinho
Yesterday me and my lab celebrated #20years @mpi-cbg.de. There is a lot to say about that but the pictures from the event tell it better. Thanks city of #Dresden for the nice fireworks. That was unexpected. 10 more years or so? #LoPaTs 💕
September 7, 2025 at 7:54 AM
Yesterday me and my lab celebrated #20years @mpi-cbg.de. There is a lot to say about that but the pictures from the event tell it better. Thanks city of #Dresden for the nice fireworks. That was unexpected. 10 more years or so? #LoPaTs 💕
Reposted by Rui Gonçalo Martinho
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
September 4, 2025 at 8:22 AM
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
Reposted by Rui Gonçalo Martinho
🚨 New from our lab: Here we explored how aging contributes to harmful protein aggregation in diseases like Huntington’s & ALS.
The culprit? An overlooked aging factor — EPS8 and RAC signaling. #Aging #Longevity #Proteostasis #ALSResearch
🧵
www.nature.com/articles/s43...
The culprit? An overlooked aging factor — EPS8 and RAC signaling. #Aging #Longevity #Proteostasis #ALSResearch
🧵
www.nature.com/articles/s43...
The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation - Nature Aging
Aging is a risk factor for neurodegenerative diseases associated with protein aggregation. Here the authors identify age-related hyperactivation of EPS8/RAC signaling in C. elegans as a driver of path...
www.nature.com
September 3, 2025 at 9:19 AM
🚨 New from our lab: Here we explored how aging contributes to harmful protein aggregation in diseases like Huntington’s & ALS.
The culprit? An overlooked aging factor — EPS8 and RAC signaling. #Aging #Longevity #Proteostasis #ALSResearch
🧵
www.nature.com/articles/s43...
The culprit? An overlooked aging factor — EPS8 and RAC signaling. #Aging #Longevity #Proteostasis #ALSResearch
🧵
www.nature.com/articles/s43...
Reposted by Rui Gonçalo Martinho
Private tour of the Louvre is a special treat. They were vacuuming the Sphinx. You may not have seen a Sphinx being brushed, so I am sharing.
September 3, 2025 at 8:36 AM
Private tour of the Louvre is a special treat. They were vacuuming the Sphinx. You may not have seen a Sphinx being brushed, so I am sharing.
Reposted by Rui Gonçalo Martinho
Our new preprint is out !
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social
August 30, 2025 at 3:47 PM
Our new preprint is out !
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social
Reposted by Rui Gonçalo Martinho
The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers https://www.biorxiv.org/content/10.1101/2025.08.29.672645v1
August 30, 2025 at 7:18 AM
The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers https://www.biorxiv.org/content/10.1101/2025.08.29.672645v1