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Reposted by Rui Gonçalo Martinho

Mark Peifer (He, him) @peiferlabunc.bsky.social · 2d

Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...

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Reposted by Rui Gonçalo Martinho

Max Planck Institute of Molecular Cell Biology and Genetics @mpi-cbg.de · 6d

Are you interested in a PhD in the area of "Mechanisms of translational control during embryogenesis?" Apply now for a PhD @mpi-cbg.de! Overview of all participating RGLs: imprs.mpi-cbg.de/5761/researc...

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Reposted by Rui Gonçalo Martinho

Ferwen @ferwen.bsky.social · 5d

#FossilFriday ‘Black Beauty’, one of the smallest-known specimens of Tyrannosaurus rex, displayed at The Royal Tyrell Museum in Calgary, Alberta.
wp.me/p3ihHu-1MX

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Rui Gonçalo Martinho @martinholab.bsky.social · 8d

Quick Drosophila question: I’m planning to integrate a construct on the second chromosome but would like to avoid the attP40 landing site. Any suggestion for a good alternative attP site on chromosome II? It’s for a skeletal-muscle–related project.
Thanks! 🙂
Rui

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Rui Gonçalo Martinho @martinholab.bsky.social · 12d

www.cell.com/current-biol...

Linear covariation between germline and somatic mutation rates across ciliates and mammals

Wang et al. estimate the somatic mutation rate in a ciliate, which contains germline and somatic genomes in the same cell. They discover a linear correlation between per-year germline and somatic muta...

www.cell.com

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Reposted by Rui Gonçalo Martinho

Current Biology @currentbiology.bsky.social · 16d

Our latest issue is out!👇
www.cell.com/current-biol...

On the cover: Nautilus ≈ 🐙+🐚

(Maybe — like the Nautilus — our journal is a living fossil, believing in the interest and inspiration our readers might draw from the diversity of biological systems, questions and approaches we try to feature🙏 )

Nautiloids (pictured)—a lineage of ancient, externally shelled cephalopods—once dominated our oceans, but today, these living fossils are threatened and in need of protection from over-exploitation.

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Reposted by Rui Gonçalo Martinho

Maxim Greenberg @maxvcg.bsky.social · 23d

Very excited to share an excellent review from @teresa-urli.bsky.social, published one week before her PhD defense! We did a deep dive into the fascinating biology of the variant Polycomb complex, PRC1.6 (1/5) journals.plos.org/plosgenetics...

Epigenetic relay: Polycomb-directed DNA methylation in mammalian development

In mammals, repression of germline-specific gene expression is essential for preserving somatic cell identity and preventing disease. Germline gene silencing is often dependent on the presence of prom...

journals.plos.org

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Rui Gonçalo Martinho @martinholab.bsky.social · 24d

“Proposals by *** outgoing *** country”… ?! We need feedback from someone that really knows about this topic :)

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Reposted by Rui Gonçalo Martinho

Remco Stam @rstam.bsky.social · 24d

Chart from last year... No big change in % of US applicants, or? . marie-sklodowska-curie-actions.ec.europa.eu/news/msca-po...

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Rui Gonçalo Martinho @martinholab.bsky.social · 24d

no - because this would have reduced the % of candidates from the US, right?

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Reposted by Rui Gonçalo Martinho

Institute of Molecular Biotechnology @imbavienna.bsky.social · 29d

📰 New paper alert!

In a collaborative project with the lab of Clemens Plaschka at the IMP, the lab of Julius Brennecke has revealed how PIWI proteins kickstart transposon silencing in reproductive cells.

The findings are published in Molecular Cell: www.sciencedirect.com/science/arti...

Vienna BioCenter @viennabiocenter.bsky.social · Sep 8

How cells lock down “jumping genes”:
Researchers from IMBA and IMP identify the first protein interactions that trigger PIWI–piRNA–mediated transposon silencing, using AlphaFold predictions, genetics, biochemistry and cell biology.
Read more: www.viennabiocenter.org/about/news/t...

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Rui Gonçalo Martinho @martinholab.bsky.social · 24d

is there data supporting your statement for this call? thanks :)

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Rui Gonçalo Martinho @martinholab.bsky.social · 24d

is the US percentage for outgoing country of applicants significantly higher than last year?

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Rui Gonçalo Martinho @martinholab.bsky.social · 24d

is the US percentage for outgoing country of applicants significantly higher than last year?

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Reposted by Rui Gonçalo Martinho

Nature Portfolio @natureportfolio.nature.com · 26d

Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪

This is figure 2, which shows M. ibericus queens lay males from two different species.

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Reposted by Rui Gonçalo Martinho

Cameron Thrash @jcamthrash.bsky.social · 27d

Microtubules in Asgard archaea (h/t @lanzen.bsky.social) www.cell.com/cell/fulltex... #jcampubs

Microtubules in Asgard archaea

Discovery of heterodimeric, microtubule-forming tubulins in Asgard archaea, the closest known relatives of eukaryotes, reveals snapshots of microtubule evolution.

www.cell.com

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Rui Gonçalo Martinho @martinholab.bsky.social · Sep 8

www.biorxiv.org/content/10.1...

Rapid protamine evolution suppresses meiotic drive in Drosophila

Many animal species replace histones with protamines during spermatogenesis. Despite their importance for sperm function, protamines rapidly evolve in many species; the biological causes behind their ...

www.biorxiv.org

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Reposted by Rui Gonçalo Martinho

Phil Plait @philplait.bsky.social · Sep 7

I hope everyone on the other side of the Earth is enjoying the total lunar eclipse! Except for flat Earthers.

An image of the full Moon with a thick, fuzzy black line across the middle. The caption says, "Flat Earth eclipses are awesome".

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Reposted by Rui Gonçalo Martinho

paveltomancak.bsky.social @paveltomancak.bsky.social · Sep 7

Yesterday me and my lab celebrated #20years @mpi-cbg.de. There is a lot to say about that but the pictures from the event tell it better. Thanks city of #Dresden for the nice fireworks. That was unexpected. 10 more years or so? #LoPaTs 💕

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Rui Gonçalo Martinho @martinholab.bsky.social · Sep 4

www.nature.com/articles/d41...

Flies evolved a shock-absorber tissue used during embryonic development

The role of tissue that forms between the head and trunk of a fly embryo has been unclear. It turns out that it absorbs forces when nearby cells move and divide.

www.nature.com

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Reposted by Rui Gonçalo Martinho

paveltomancak.bsky.social @paveltomancak.bsky.social · Sep 4

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

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David Vilchez @thevilchezlab.bsky.social · Sep 3

🚨 New from our lab: Here we explored how aging contributes to harmful protein aggregation in diseases like Huntington’s & ALS.
The culprit? An overlooked aging factor — EPS8 and RAC signaling. #Aging #Longevity #Proteostasis #ALSResearch
🧵
www.nature.com/articles/s43...

The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation - Nature Aging

Aging is a risk factor for neurodegenerative diseases associated with protein aggregation. Here the authors identify age-related hyperactivation of EPS8/RAC signaling in C. elegans as a driver of path...

www.nature.com

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Reposted by Rui Gonçalo Martinho

Frances Arnold @francesarnold.bsky.social · Sep 3

Private tour of the Louvre is a special treat. They were vacuuming the Sphinx. You may not have seen a Sphinx being brushed, so I am sharing.

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Reposted by Rui Gonçalo Martinho

Hadi Boukhatmi @muscleflylab.bsky.social · Aug 30

Our new preprint is out !
We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles.
Check it out and please share
@igdrennes.bsky.social

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Reposted by Rui Gonçalo Martinho

bioRxiv Molecular Biology @biorxiv-molbio.bsky.social · Aug 30

The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers https://www.biorxiv.org/content/10.1101/2025.08.29.672645v1

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