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Reposted by Nixa Sedes, MD

JAMA

@jama.com

IgA nephropathy is the most common cause of immune-mediated glomerular disease worldwide.

📌 This Review summarizes the pathophysiology, epidemiology, clinical presentation, diagnosis, treatment, and prognosis of primary IgA nephropathy in adults.

ja.ma/4jWE9ag

Diagram titled, 'Figure 1. Pathophysiology of IgA Nephropathy,' shows 'Four-hit hypothesis' of primary IgA nephropathy (IgAN). Steps include production of IgA1 immunoglobulins, entry into circulation, formation of immune complexes & deposition in glomerular mesangium.

January 26, 2026 at 4:30 PM

Nixa Sedes, MD

@nixassedes.bsky.social

Sustainable Cellulose Ionogels With Promising Physical Structure, Properties, and Applications🔓 - Wang - Advanced Physics Research - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/...

Sustainable Cellulose Ionogels With Promising Physical Structure, Properties, and Applications

This study presents a comprehensive overview of cellulose functional gels, focusing on their molecular network design and physical properties. The extensive potential applications of cellulose gels i....

advanced.onlinelibrary.wiley.com

January 26, 2026 at 11:36 AM

Nixa Sedes, MD

@nixassedes.bsky.social

Subsistence Strategies in Bronze Age Southeastern Iberia: Insights from Motilla del Azuer Phase 2 (ca. 1950 - 1875 cal BC)🔓
papers.ssrn.com/sol3/papers....

Subsistence Strategies in Bronze Age Southeastern Iberia: Insights from Motilla del Azuer Phase 2 (ca. 1950 - 1875 cal BC)

This study analyses Phase 2 of Motilla del Azuer to refine current knowledge of subsistence strategies and livestock management. Zooarchaeological analysis reve

papers.ssrn.com

January 26, 2026 at 11:31 AM

Nixa Sedes, MD

@nixassedes.bsky.social

Reducing sodium in everyday foods may yield heart-health benefits across populations
newsroom.heart.org/news/reducin...

Reducing sodium in everyday foods may yield heart-health benefits across populations

Research Highlights: A study in France found that if sodium reduction targets focused on reducing salt in baguettes and other breads, they could lower daily salt intake by 0.35 grams per person and re...

newsroom.heart.org

January 26, 2026 at 11:03 AM

Nixa Sedes, MD

@nixassedes.bsky.social

The network architecture of general intelligence in the human connectome🔓
www.nature.com/articles/s41...

The network architecture of general intelligence in the human connectome - Nature Communications

General intelligence (g) emerges from the global topology of the human connectome. Modeling structure and function in 831 adults reveals g engages distributed networks, weak long-range connections, mo...

www.nature.com

January 26, 2026 at 10:51 AM

Nixa Sedes, MD

@nixassedes.bsky.social

Reconstructing the Classical and Post‐Classical Agricultural Landscape of the Udhruh Qanat in Wādī al‐Fiqai, Southern Jordan🔓 - Hoosbeek - 2026 - Geoarchaeology - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...

Reconstructing the Classical and Post‐Classical Agricultural Landscape of the Udhruh Qanat in Wādī al‐Fiqai, Southern Jordan

The cities of Petra and Udhruh were administrative and cultural centers in southern Jordan from Nabataean through Roman and Byzantine times into the early Islamic periods (first century BCE to eighth....

onlinelibrary.wiley.com

January 25, 2026 at 12:30 PM

Nixa Sedes, MD

@nixassedes.bsky.social

Bradyzoite subtypes rule the crossroads of Toxoplasma development🔓
www.nature.com/articles/s41...

Bradyzoite subtypes rule the crossroads of Toxoplasma development - Nature Communications

The authors investigate the heterogeneity of Toxoplasma bradyzoites prior to recrudescence. Tissue cysts from infected mice harbor multiple bradyzoite subtypes with distinct developmental fates as evi...

www.nature.com

January 24, 2026 at 4:47 PM

Nixa Sedes, MD

@nixassedes.bsky.social

Biography of a Levantine dolmen during the Early Bronze Age: construction, reuse and memory at Rjile (Kufr Yuba, North Jordan)🔓
www.sciencedirect.com/science/arti...

Biography of a Levantine dolmen during the Early Bronze Age: construction, reuse and memory at Rjile (Kufr Yuba, North Jordan)

The architectural and ritual biography of dolmen ST_30 in the Rjile necropolis (Kufr Yuba, Jordan) provides new chronological and cultural insights in…

www.sciencedirect.com

January 24, 2026 at 4:42 PM

Nixa Sedes, MD

@nixassedes.bsky.social

Stone and the gods: religious cognition and stone carving in first millennium AD northern Britain 🔓
www.tandfonline.com/doi/full/10....

Stone and the gods: religious cognition and stone carving in first millennium AD northern Britain

Archaeology often adheres to established periodisations, sometimes overlooking long-term societal transformations. One such shift in Northern Britain during the first millennium AD was the emergenc...

www.tandfonline.com

January 24, 2026 at 12:05 PM

Nixa Sedes, MD

@nixassedes.bsky.social

What Exactly Is Cardiometabolic HFpEF: A Phenotype or an Endotype?🔓
www.ahajournals.org/doi/10.1161/...

What Exactly Is Cardiometabolic HFpEF: A Phenotype or an Endotype? | Circulation: Heart Failure

www.ahajournals.org

January 24, 2026 at 11:18 AM

Reposted by Nixa Sedes, MD

Neuron

@cp-neuron.bsky.social

The layer 6b theory of attention

Zolnik et al. propose that the long-overlooked neocortical layer 6b (L6b) supports a key circuit for attention and related cognitive functions. L6b integrates neuromodulatory and cortical feedback to trigger, sustain, and precisely control higher-order thalamocortical loops needed for attentive processing.

dlvr.it

January 23, 2026 at 4:23 PM

Nixa Sedes, MD

@nixassedes.bsky.social

Systematic Review on the Epidemiology, Diagnostics and Management of Leishmaniasis Recidivans🔓
www.sciencedirect.com/science/arti...

Systematic Review on the Epidemiology, Diagnostics and Management of Leishmaniasis Recidivans

One of the most severe and least understood forms of cutaneous leishmaniasis (CL) is leishmaniasis recidivans (LR), a chronic variant in which lesions…

www.sciencedirect.com

January 23, 2026 at 4:27 PM

Reposted by Nixa Sedes, MD

Journal of Clinical Lipidology

@lipidjournal.bsky.social

#JCLSpotlight: New research shows PCSK9 inhibitors and inclisiran significantly reduce visit-to-visit LDL-C variability vs standard therapy. Lower LDL-C variability was linked to fewer CV events, highlighting lipid stability as a key treatment goal.

Read more: https://ow.ly/qLkI50Y0Gbh

January 23, 2026 at 2:01 PM

Nixa Sedes, MD

@nixassedes.bsky.social

A Textile‐Based Optical Force Myography (oFMG) Human‐Machine Interface for Gesture Recognition🔓 - Hoang - 2026 - Advanced Sensor Research - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/...

A Textile‐Based Optical Force Myography (oFMG) Human‐Machine Interface for Gesture Recognition

This study presents a textile-based optical force myography (oFMG) sensor for human-machine interface applications. The textile oFMG sensor is designed for a thin, compact, and comfortable profile ba...

advanced.onlinelibrary.wiley.com

January 23, 2026 at 12:41 PM

Nixa Sedes, MD

@nixassedes.bsky.social

A Cultural Approach to Musical Care: Theoretical Perspectives and Future Directions🔓
journals.sagepub.com/doi/full/10....

A Cultural Approach to Musical Care: Theoretical Perspectives and Future Directions - Jonathan Tang, 2026

In this article, I introduce a cultural approach to musical care by situating health, well-being, and music engagement within specific cultural meaning systems....

journals.sagepub.com

January 23, 2026 at 11:42 AM

Nixa Sedes, MD

@nixassedes.bsky.social

Gut microbiome–driven colorectal cancer via immune, metabolic, neural, and endocrine axes reprogramming🔓
www.nature.com/articles/s41...

Gut microbiome–driven colorectal cancer via immune, metabolic, neural, and endocrine axes reprogramming - npj Biofilms and Microbiomes

npj Biofilms and Microbiomes - Gut microbiome–driven colorectal cancer via immune, metabolic, neural, and endocrine axes reprogramming

www.nature.com

January 23, 2026 at 11:33 AM

Nixa Sedes, MD

@nixassedes.bsky.social

Efficacy for LDL-C–lowering and Safety of Pemafibrate Extended-release Formulation in Patients with Statin-intolerant Hypercholesterolemia: A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group trial🔓
www.sciencedirect.com/science/arti...

Efficacy for LDL-C–lowering and Safety of Pemafibrate Extended-release Formulation in Patients with Statin-intolerant Hypercholesterolemia: A Phase 3 Multicenter, Randomized, Double-blind, Placebo-con...

Management of low-density lipoprotein cholesterol (LDL-C) in patients who are statin-intolerant requires treatment options beyond statins. Pemafibrate…

www.sciencedirect.com

January 23, 2026 at 11:10 AM

Nixa Sedes, MD

@nixassedes.bsky.social

Creatine Supplementation and Brain Health: Methodological Challenges, Current Evidence, and Translational Perspectives🔓
www.sciencedirect.com/science/arti...

Creatine Supplementation and Brain Health: Methodological Challenges, Current Evidence, and Translational Perspectives

Although creatine supplementation holds promising translational value for supporting brain health and cognitive function, the current body of literatu…

www.sciencedirect.com

January 23, 2026 at 11:06 AM

Reposted by Nixa Sedes, MD

Journal of Experimental Medicine

@jem.org

#Claudin 1-mediated positioning of DC1 to mTECs is essential for maintenance of central #tolerance. From Jiří Březina, Dominik Filipp and colleagues @imgprague.bsky.social: rupress.org/jem/article/...

📘 In #Immunology Update Winter 2026 👉 rupress.org/jem/collecti...

January 22, 2026 at 4:15 PM

Reposted by Nixa Sedes, MD

The Journal of Physiology

@jphysiol.bsky.social

Edoardo Lecce, Paolo Amoruso, Francesco Felici and Ilenia Bazzucchi (Department of Movement, Human and Health Sciences, University of Foro Italico) #review the #resistance training-induced #adaptations in the #neuromuscular system.

📜 physoc.onlinelibrary.wiley.com/doi/10.1113/...

January 22, 2026 at 4:29 PM

Nixa Sedes, MD

@nixassedes.bsky.social

Foundation models for electrocardiogram interpretation: clinical implications 🔓 academic.oup.com/eurheartj/ar...

Foundation models for electrocardiogram interpretation: clinical implications

AbstractBackground and Aims. The 12-lead electrocardiogram (ECG) remains a cornerstone of cardiac diagnostics, yet existing artificial intelligence (AI) so

academic.oup.com

January 22, 2026 at 2:07 PM

Nixa Sedes, MD

@nixassedes.bsky.social

Ubiquitination dynamics in human tumour viruses: Viral infection, oncogenesis and antiviral therapy 🔓 - Trejo‐Cerro - 2026 - The FEBS Journal - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1111/...

FEBS Press

The ubiquitin system is essential for cellular homeostasis and regulates many processes. Viruses, including oncogenic ones, exploit or evade this system to survive and replicate. This review explores....

febs.onlinelibrary.wiley.com

January 22, 2026 at 11:11 AM

Nixa Sedes, MD

@nixassedes.bsky.social

Diagnosis and Management of Isolated Laryngeal Sarcoidosis: A Systematic Review 🔓 - Malhotra - Otolaryngology–Head and Neck Surgery - Wiley Online Library aao-hnsfjournals.onlinelibrary.wiley.com/doi/full/10....