Nixa Sedes, MD
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nixassedes.bsky.social
Nixa Sedes, MD
@nixassedes.bsky.social
260 followers 480 following 7K posts
MD Internal Medicine Specialist Avid reader Science and Technology Philosophy History Astronomy Archaeology and Paleontology lover Proud mother of one
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nixassedes.bsky.social
Sewers to Seas: exploring pathogens and antimicrobial resistance on microplastics from hospital wastewater to marine environments🔓
www.sciencedirect.com/science/arti...
Sewers to Seas: exploring pathogens and antimicrobial resistance on microplastics from hospital wastewater to marine environments
Microplastic particles are extremely prevalent environmental pollutants which support microbial biofilms known as the ‘plastisphere’. Antimicrobial re…
www.sciencedirect.com
November 25, 2025 at 4:44 PM
nixassedes.bsky.social
Role of Circadian Health in Cardiometabolic Health and Disease Risk: A Scientific Statement From the American Heart Association🔓
www.ahajournals.org/doi/10.1161/...
Role of Circadian Health in Cardiometabolic Health and Disease Risk: A Scientific Statement From the American Heart Association | Circulation
Cardiovascular and metabolic health are influenced by the circadian system, which regulates 24-hour rhythms across numerous physiologic processes. Disruptions to circadian rhythmicity can adversely af...
www.ahajournals.org
November 25, 2025 at 10:36 AM
Reposted by Nixa Sedes, MD
jama.com
Continuous glucose monitoring (CGM) enables real-time assessment of glucose trends in individuals with type 2 #diabetes, complementing or replacing fingerstick and HbA1c monitoring.

💡 This JAMA Insights discusses CGM use for type 2 diabetes.

ja.ma/4ogw8xz
JAMA Insights: Continuous Glucose Monitoring, published November 24, 2025. The image shows glucose monitoring data, including time in ranges, glucose metrics, ambulatory glucose profile (AGP), and daily glucose profiles.
November 24, 2025 at 5:00 PM
nixassedes.bsky.social
Colchicine and cardiovascular outcomes in MINOCA: A retrospective cohort study🔓
www.sciencedirect.com/science/arti...
Colchicine and cardiovascular outcomes in MINOCA: A retrospective cohort study
MINOCA accounts for 5 %–15 % of myocardial infarctions and is defined by <50 % coronary stenosis without an alternative diagnosis, with heterogeneous …
www.sciencedirect.com
November 24, 2025 at 2:58 PM
nixassedes.bsky.social
Heme in Bacterial Pathogenesis and as an Antimicrobial Target🔓 | Chemical Reviews pubs.acs.org/doi/10.1021/...
Heme in Bacterial Pathogenesis and as an Antimicrobial Target
Heme is an essential molecule required for critical biochemical processes in most vertebrates and bacteria. During infections, vertebrate hosts sequester heme away from invading pathogens, a process k...
pubs.acs.org
November 23, 2025 at 10:12 PM
Reposted by Nixa Sedes, MD
chemsocrev.rsc.org
From our 2025 #PioneeringInvestigators collection...

"Hydrogen-bonded π-conjugated supramolecular polymers" by Pedro Ximenis, Daniel Martínez, Llorenç Rubert and Bartolome Soberats

Read the #OpenAccess review here 👉🔓
Hydrogen-bonded π-conjugated supramolecular polymers
The self-assembly of π-conjugated molecules offers a promising route for designing advanced functional materials with tailored optical and electronic properties. Owing to their nature, organic π-conjugated scaffolds spontaneously assemble by π–π stacking, while the introduction of hydrogen-bonding (H-bonding) inter
pubs.rsc.org
November 23, 2025 at 11:57 AM
nixassedes.bsky.social
Regulatory T cells in liver metastases: emerging and divergent roles in tumour progression🔓
egastroenterology.bmj.com//content/3/4...
Regulatory T cells in liver metastases: emerging and divergent roles in tumour progression
Liver metastases (LMs) pose a significant burden of morbidity and mortality, resulting in a worse prognosis for many primary malignancies. Despite advancements in cancer treatment, such as immunothera...
egastroenterology.bmj.com
November 23, 2025 at 1:14 PM
nixassedes.bsky.social
Chronic pain and hypertension and mediation role of inflammation and depression🔓
pmc.ncbi.nlm.nih.gov/articles/PMC...
Chronic pain and hypertension and mediation role of inflammation and depression
The association between chronic pain and incident hypertension is unclear. This study aimed to investigate the associations between different pain characteristics (pain type, location and spread) and incident hypertension, and whether they were ...
pmc.ncbi.nlm.nih.gov
November 23, 2025 at 11:28 AM
nixassedes.bsky.social
Glioblastoma and other Primary Brain Malignancies in Adults. A Review🔓
pmc.ncbi.nlm.nih.gov/articles/PMC...
Glioblastoma and other Primary Brain Malignancies in Adults. A Review
Malignant primary brain tumors cause over 15,000 deaths per year in the United States. The annual incidence of primary malignant brain tumors is approximately 7 per 100,000 individuals and increases with age. Five-year survival is about 67%. ...
pmc.ncbi.nlm.nih.gov
November 23, 2025 at 11:00 AM
Reposted by Nixa Sedes, MD
europeanrespsoc.bsky.social
This article presents the pathophysiological mechanisms by which patients with pleural effusion experience dyspnoea and the mechanism by which these patients may clinically benefit from thoracentesis, regardless of the size of the pleural effusion. https://bit.ly/486GQC7
November 22, 2025 at 4:06 PM
nixassedes.bsky.social
Microfluidics meets cell-free systems: from molecular engineering to synthetic cells🔓
www.sciencedirect.com/science/arti...
Microfluidics meets cell-free systems: from molecular engineering to synthetic cells
Cell-free systems have emerged as a powerful platform for protein production, characterization, and bottom-up construction of artificial cells, offeri…
www.sciencedirect.com
November 22, 2025 at 4:25 PM
Reposted by Nixa Sedes, MD
genesndiseases.bsky.social
This review explores the role of #YTHDF2 in #ImmuneRegulation and #InflammatorySignaling, emphasizing its contribution to #disease #pathogenesis, the development of selective #therapeutic agents, and the challenges of #ClinicalTranslation. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...
November 22, 2025 at 1:41 AM
nixassedes.bsky.social
Imaging the momentum of charged particles without background noise pubs.aip.org/aip/sci/arti...
Imaging the momentum of charged particles without background noise
Modifications to velocity map imaging spectrometer eliminate 99.9% of background noise.
pubs.aip.org
November 22, 2025 at 11:44 AM
nixassedes.bsky.social
Ceramic production and exchange in the Chavín heartland: an archaeometric study from Canchas Uckro (1100 − 800 BCE), Ancash, Peru🔓
link.springer.com/article/10.1...
Ceramic production and exchange in the Chavín heartland: an archaeometric study from Canchas Uckro (1100 − 800 BCE), Ancash, Peru - Archaeological and Anthropological Sciences
Canchas Uckro is one of several settlements surrounding the ceremonial and urban center of Chavín de Huántar (c. 1100 − 400 BCE). In this paper, we explore the relationship between these two sites thr...
link.springer.com
November 22, 2025 at 11:36 AM
nixassedes.bsky.social
The microbiome shaping cancer development, progression, and therapeutic response🔓
journals.physiology.org/doi/full/10....
The microbiome shaping cancer development, progression, and therapeutic response | Physiological Genomics | American Physiological Society
The human microbiome is emerging as a key regulator of cancer biology, modulating tumor development, immune dynamics, and therapeutic responses across diverse malignancies. In this review, recent insi...
journals.physiology.org
November 22, 2025 at 11:25 AM
nixassedes.bsky.social
From development to regeneration: the endothelial interface in lung injury and repair🔓
journals.physiology.org/doi/full/10....
From development to regeneration: the endothelial interface in lung injury and repair | American Journal of Physiology-Lung Cellular and Molecular Physiology | American Physiological Society
The pulmonary alveolar-capillary niche is a highly specialized interface that balances gas exchange with maintenance functions and repair. Advances in single cell transcriptomics have uncovered endoth...
journals.physiology.org
November 22, 2025 at 11:20 AM
nixassedes.bsky.social
Glycosaminoglycans in gastrointestinal cancer: from biosynthesis to tumor signatures🔓
journals.physiology.org/doi/full/10....
Glycosaminoglycans in gastrointestinal cancer: from biosynthesis to tumor signatures | American Journal of Physiology-Cell Physiology | American Physiological Society
Glycosaminoglycans (GAGs) are major components of the cells glycocalyx and extracellular matrix (ECM), with important roles in both physiological and disease contexts. The biosynthesis of the long and...
journals.physiology.org
November 22, 2025 at 11:18 AM
Reposted by Nixa Sedes, MD
kidneyint.bsky.social
A national cohort study examined the risk of severe infection and infection-related mortality in patients with chronic kidney disease with lupus nephritis in comparison to other chronic kidney disease etiologies

doi.org/10.1016/j.kint.2025.10.010

#OpenAccess #MedSky #NephSky #ckd @ki.se
November 21, 2025 at 9:36 PM
Reposted by Nixa Sedes, MD
aga-cmgh.bsky.social
🧠 Did you know that your gut talks to your brain!? Enterochromaffin cells in the intestine sense nutrients, hormones and signals, releasing serotonin to control motility, satiety and discomfort.
📣 Read more on this featured article!
🔗 ow.ly/4MMv50XtwXq
🏷️ #GIHealth #GIX
November 21, 2025 at 9:38 PM
nixassedes.bsky.social
Vascular malformations: from genetics to therapeutics🔓 | EMBO Molecular Medicine www.embopress.org/doi/full/10....
Vascular malformations: from genetics to therapeutics | EMBO Molecular Medicine
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
www.embopress.org
November 21, 2025 at 10:29 PM
nixassedes.bsky.social
New tech can unlock mysteries of genome’s hidden half
news.cornell.edu/stories/2025...
New tech can unlock mysteries of genome’s hidden half | Cornell Chronicle
Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome.
news.cornell.edu
November 21, 2025 at 10:20 PM
nixassedes.bsky.social
Observation of proton tunneling correlated with phonons and electrons in Pd | Science Advances www.science.org/doi/full/10....
Observation of proton tunneling correlated with phonons and electrons in Pd
Temperature-dependent quantum tunneling was observed for hydrogen hopping from tetrahedral to octahedral sites in palladium.
www.science.org
November 21, 2025 at 10:03 PM
nixassedes.bsky.social
Neuroimaging Findings Across the Spectrum of Kidney Disease
A Systematic Review and Meta-Analysis🔓
www.neurology.org/doi/full/10....
Neuroimaging Findings Across the Spectrum of Kidney Disease | Neurology Open Access
Background and ObjectivesNeurologic impairments across the spectrum of kidney disease are increasingly recognized yet remain poorly characterized. The objective of this study was to synthesize neuroim...
www.neurology.org
November 21, 2025 at 9:59 PM
nixassedes.bsky.social
Movement Disorders in Antibody-Associated Neurologic Diseases
A Nationwide Study🔓
www.neurology.org/doi/full/10....
Movement Disorders in Antibody-Associated Neurologic Diseases | Neurology Neuroimmunology & Neuroinflammation
Background and ObjectivesAntibody-associated neurologic diseases often present with movement disorders (MDs). The frequency and clinical course of specific MDs in most antibody-associated disease subt...
www.neurology.org
November 21, 2025 at 9:56 PM
Reposted by Nixa Sedes, MD
acr-journals.bsky.social
Persistent pain remains a major challenge in inflammatory arthritis, even when joint inflammation is well controlled. Review in Arthritis Care & Research looks at brain-focused research and neuroimaging in rheumatology practice.

📄 🔓 Read the open access review: doi.org/10.1002/acr....

#Medsky
Beyond Inflammation: Why Understanding the Brain Matters in Inflammatory Arthritis. Graphical abstract created using BioRender
November 21, 2025 at 1:45 PM