Pia Leete
@pialeete.bsky.social
Current RD Lawrence Independent (T1)Diabetes Research Scientist
Also Mum, wife, ally, dreamer, long distance runner and champion of truly creative thought.
(ex: busker/woodworker/ stiltwalker/ traveller/ award winning artist)
Also Mum, wife, ally, dreamer, long distance runner and champion of truly creative thought.
(ex: busker/woodworker/ stiltwalker/ traveller/ award winning artist)
Yes:::
Yes::: Yes:::
🧪🧪🥼🥼🔬🔬
Random patterns of exquisite beauty - revealing random ideas - that occassionally - just possibly - when reflected upon - may just change the way we think about what we think about!!
🧪🥼🔬
Yes::: Yes:::
🧪🧪🥼🥼🔬🔬
Random patterns of exquisite beauty - revealing random ideas - that occassionally - just possibly - when reflected upon - may just change the way we think about what we think about!!
🧪🥼🔬
I used to think I wanted to be a scientist, but when I really reflect, I just wanted to look at random things through fancy microscopes.
November 11, 2025 at 10:13 PM
Yes:::
Yes::: Yes:::
🧪🧪🥼🥼🔬🔬
Random patterns of exquisite beauty - revealing random ideas - that occassionally - just possibly - when reflected upon - may just change the way we think about what we think about!!
🧪🥼🔬
Yes::: Yes:::
🧪🧪🥼🥼🔬🔬
Random patterns of exquisite beauty - revealing random ideas - that occassionally - just possibly - when reflected upon - may just change the way we think about what we think about!!
🧪🥼🔬
Congratulations: This image is absolutely stunning
Do yourself a favour 🦋- take a moment - open the pic - dive into the beauty of microscope for a moment - just to really remember and pause in awe at the elegance of nature ❤️ (even if you do get #allergies!!)
#microscopy #talent #nature #science
Do yourself a favour 🦋- take a moment - open the pic - dive into the beauty of microscope for a moment - just to really remember and pause in awe at the elegance of nature ❤️ (even if you do get #allergies!!)
#microscopy #talent #nature #science
Grateful to see one my #superresolution #pollen images won 2nd place at the 2025 @bioimagingna.bsky.social image contest!
www.bioimagingnorthamerica.org/image-contes...
#microscopy #confocal #botany #plantscience #allergies #bioimaging
www.bioimagingnorthamerica.org/image-contes...
#microscopy #confocal #botany #plantscience #allergies #bioimaging
October 14, 2025 at 9:42 PM
Congratulations: This image is absolutely stunning
Do yourself a favour 🦋- take a moment - open the pic - dive into the beauty of microscope for a moment - just to really remember and pause in awe at the elegance of nature ❤️ (even if you do get #allergies!!)
#microscopy #talent #nature #science
Do yourself a favour 🦋- take a moment - open the pic - dive into the beauty of microscope for a moment - just to really remember and pause in awe at the elegance of nature ❤️ (even if you do get #allergies!!)
#microscopy #talent #nature #science
What an incredibly poignant piece of reporting by the BBC.
Lots to think about.
#generosity
#reciprocity
#altruism of the highest order.
#future_docs
#science
🧪
www.bbc.co.uk/news/article...
Lots to think about.
#generosity
#reciprocity
#altruism of the highest order.
#future_docs
#science
🧪
www.bbc.co.uk/news/article...
BBC presenter's shock over mum's body donation revelation
BBC presenter Lucy Owen finds out why her mum wants to donate her body to medical science.
www.bbc.co.uk
October 12, 2025 at 5:25 PM
What an incredibly poignant piece of reporting by the BBC.
Lots to think about.
#generosity
#reciprocity
#altruism of the highest order.
#future_docs
#science
🧪
www.bbc.co.uk/news/article...
Lots to think about.
#generosity
#reciprocity
#altruism of the highest order.
#future_docs
#science
🧪
www.bbc.co.uk/news/article...
Any chance we think this might actually work?
Or are we just compounding our doom by splitting the pack even further … ?
Answers on a postcard.
Or are we just compounding our doom by splitting the pack even further … ?
Answers on a postcard.
Latest poll puts Greens just two points behind Labour. When I said we weren't here to be disappointed in Labour but to replace them, I meant it.
Join us and let's make hope normal again.
join.greenparty.org.uk
Join us and let's make hope normal again.
join.greenparty.org.uk
October 10, 2025 at 6:39 AM
Any chance we think this might actually work?
Or are we just compounding our doom by splitting the pack even further … ?
Answers on a postcard.
Or are we just compounding our doom by splitting the pack even further … ?
Answers on a postcard.
This piqued my interest …
Will there be a sting in the tail??
Will there be a sting in the tail??
💉 From scarcity to self-reliance—Africa’s insulin race is on.
#Nigeria signs deal with #China to start producing #insulin—joining Egypt & South Africa.
📈With diabetes set to affect 60M Africans by 2050, local production is vital for affordable access.
✍️ @kerrycullinan.bsky.social
📖⬇️ & 🙏🔁
#Nigeria signs deal with #China to start producing #insulin—joining Egypt & South Africa.
📈With diabetes set to affect 60M Africans by 2050, local production is vital for affordable access.
✍️ @kerrycullinan.bsky.social
📖⬇️ & 🙏🔁
Nigeria Deal With China Will Enable It To Make Insulin Alongside Egypt And South Africa - Health Policy Watch
A deal with China will enable Nigeria to join Egypt and South Africa as a producer of insulin, the drug that is essential to control diabetes.
healthpolicy-watch.news
October 9, 2025 at 7:50 PM
This piqued my interest …
Will there be a sting in the tail??
Will there be a sting in the tail??
Reposted by Pia Leete
In any other country, if federal agents fired upon journalists when unprovoked — what would we call it?
If federal agents marched down streets demanding papers — what would we say?
Authoritarianism — let’s not pretend it’s something else when it happens in our American cities.
If federal agents marched down streets demanding papers — what would we say?
Authoritarianism — let’s not pretend it’s something else when it happens in our American cities.
September 30, 2025 at 12:01 AM
In any other country, if federal agents fired upon journalists when unprovoked — what would we call it?
If federal agents marched down streets demanding papers — what would we say?
Authoritarianism — let’s not pretend it’s something else when it happens in our American cities.
If federal agents marched down streets demanding papers — what would we say?
Authoritarianism — let’s not pretend it’s something else when it happens in our American cities.
#research #biomed_researchers
#diabetes_researchers
Just putting my head above the parapet to ask :
How many have returned to X?
And if you have: why?
And if you haven’t and 🦋 isn’t meeting your needs - where else do you go most regularly?
(Genuinely curious question!)
#diabetes_researchers
Just putting my head above the parapet to ask :
How many have returned to X?
And if you have: why?
And if you haven’t and 🦋 isn’t meeting your needs - where else do you go most regularly?
(Genuinely curious question!)
September 9, 2025 at 3:03 PM
#research #biomed_researchers
#diabetes_researchers
Just putting my head above the parapet to ask :
How many have returned to X?
And if you have: why?
And if you haven’t and 🦋 isn’t meeting your needs - where else do you go most regularly?
(Genuinely curious question!)
#diabetes_researchers
Just putting my head above the parapet to ask :
How many have returned to X?
And if you have: why?
And if you haven’t and 🦋 isn’t meeting your needs - where else do you go most regularly?
(Genuinely curious question!)
Reposted by Pia Leete
By betraying his voters so comprehensively and so soon, Keir Starmer has done us a favour. He has given us 4 years to design the government we want.
In this week's column I explain how it can be done. There's massive
potential, but we need to start now. 🧵
www.theguardian.com/commentisfre...
In this week's column I explain how it can be done. There's massive
potential, but we need to start now. 🧵
www.theguardian.com/commentisfre...
How we can smash Britain’s two-party system for good at the next election | George Monbiot
Labour is beyond repair. Time for a co-ordinated strategy to support progressive parties committed to electoral reform, says Guardian columnist George Monbiot
www.theguardian.com
May 27, 2025 at 7:20 AM
By betraying his voters so comprehensively and so soon, Keir Starmer has done us a favour. He has given us 4 years to design the government we want.
In this week's column I explain how it can be done. There's massive
potential, but we need to start now. 🧵
www.theguardian.com/commentisfre...
In this week's column I explain how it can be done. There's massive
potential, but we need to start now. 🧵
www.theguardian.com/commentisfre...
#topviewedarticle in Diabetic Medicine in 2024 (n top 10% anyway)
🧪🚀✨
This paper was all in my voice! Too long but 😍. It was the first commentary Ive written about the science I’m so passionate about! (I do still need to learn about white space!!!)
onlinelibrary.wiley.com/doi/full/10....
🧪🚀✨
This paper was all in my voice! Too long but 😍. It was the first commentary Ive written about the science I’m so passionate about! (I do still need to learn about white space!!!)
onlinelibrary.wiley.com/doi/full/10....
<em>Diabetic Medicine</em> | Diabetes UK Journal | Wiley Online Library
Aims
This review aims to introduce research in the pancreas to a broader audience. The pancreas is a heterocrine gland residing deep within our abdominal cavity. It is the home to our islets, which .....
onlinelibrary.wiley.com
April 16, 2025 at 9:15 PM
#topviewedarticle in Diabetic Medicine in 2024 (n top 10% anyway)
🧪🚀✨
This paper was all in my voice! Too long but 😍. It was the first commentary Ive written about the science I’m so passionate about! (I do still need to learn about white space!!!)
onlinelibrary.wiley.com/doi/full/10....
🧪🚀✨
This paper was all in my voice! Too long but 😍. It was the first commentary Ive written about the science I’m so passionate about! (I do still need to learn about white space!!!)
onlinelibrary.wiley.com/doi/full/10....
As an example: Trump administration cuts $4m to Princeton’s climate research funding:
The scope of this madness is 🤯
For all the scientists in America affected…and the work for the rest of us that they do…I weep.
I can only think we fight it with hope, patience, and continued rebellion ….
The scope of this madness is 🤯
For all the scientists in America affected…and the work for the rest of us that they do…I weep.
I can only think we fight it with hope, patience, and continued rebellion ….
April 11, 2025 at 7:12 AM
As an example: Trump administration cuts $4m to Princeton’s climate research funding:
The scope of this madness is 🤯
For all the scientists in America affected…and the work for the rest of us that they do…I weep.
I can only think we fight it with hope, patience, and continued rebellion ….
The scope of this madness is 🤯
For all the scientists in America affected…and the work for the rest of us that they do…I weep.
I can only think we fight it with hope, patience, and continued rebellion ….
Still so excited by our paper!
Multidisciplinary, creative, innovative & fun: this was “doing” science at its best 🚀🧪
Helpful that it a) reveals (quantitatively) that human #islets retain a conserved mantle-core structure & b) offers a nuanced tool to compare the subtleties of data distributions.
Multidisciplinary, creative, innovative & fun: this was “doing” science at its best 🚀🧪
Helpful that it a) reveals (quantitatively) that human #islets retain a conserved mantle-core structure & b) offers a nuanced tool to compare the subtleties of data distributions.
Using a fusion of #mathematics and #spatial_biology, a study employing quantitative tools (including the #Earth_Movers_Distance metric) tests the existence of a #mantle_core_structure in #human_islets in #T1D link.springer.com/article/10.1... 🔓
Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes - Diabetologia
Aims/hypothesis The organisation and cellular architecture of islets of Langerhans are critical to the physiological regulation of hormone secretion but it is debated whether human islets adhere to th...
link.springer.com
March 29, 2025 at 6:24 PM
Still so excited by our paper!
Multidisciplinary, creative, innovative & fun: this was “doing” science at its best 🚀🧪
Helpful that it a) reveals (quantitatively) that human #islets retain a conserved mantle-core structure & b) offers a nuanced tool to compare the subtleties of data distributions.
Multidisciplinary, creative, innovative & fun: this was “doing” science at its best 🚀🧪
Helpful that it a) reveals (quantitatively) that human #islets retain a conserved mantle-core structure & b) offers a nuanced tool to compare the subtleties of data distributions.
Humbled by the women in science before me: 🧪🔬🥼🚀
On this day in 1879, Maud Menten was born in Port Lambton, Ontario.
In her work as a medical researcher, she became a leading expert in histochemistry and enzyme kinetics while fighting against sexism in her field.
Let's learn more about her life!
🧵1/10
In her work as a medical researcher, she became a leading expert in histochemistry and enzyme kinetics while fighting against sexism in her field.
Let's learn more about her life!
🧵1/10
March 21, 2025 at 6:35 AM
Humbled by the women in science before me: 🧪🔬🥼🚀
Reposted by Pia Leete
Calling all...
🔬 Microscopists
💻 BioImage Analysts
👩🔬 Life Scientists
📅 Save the Date
The 5th edition of the Crick BioImage Analysis Symposium will take place on November 24/25th 2025.
More details to follow...
#CBIAS2025
🔬 Microscopists
💻 BioImage Analysts
👩🔬 Life Scientists
📅 Save the Date
The 5th edition of the Crick BioImage Analysis Symposium will take place on November 24/25th 2025.
More details to follow...
#CBIAS2025
March 17, 2025 at 8:19 PM
Calling all...
🔬 Microscopists
💻 BioImage Analysts
👩🔬 Life Scientists
📅 Save the Date
The 5th edition of the Crick BioImage Analysis Symposium will take place on November 24/25th 2025.
More details to follow...
#CBIAS2025
🔬 Microscopists
💻 BioImage Analysts
👩🔬 Life Scientists
📅 Save the Date
The 5th edition of the Crick BioImage Analysis Symposium will take place on November 24/25th 2025.
More details to follow...
#CBIAS2025
So sad to read :
How is it possible that this is happening to science in 2025 !!!!?????
How is it possible that this is happening to science in 2025 !!!!?????
This is horrible to post, but I may as well post it. We are essentially shutting down research operations in my group, which is focused on treatments for pediatric brain cancer. I’m a well funded investigator, and there’s no choice. Science can’t function without the stability of NIH
March 15, 2025 at 9:14 PM
So sad to read :
How is it possible that this is happening to science in 2025 !!!!?????
How is it possible that this is happening to science in 2025 !!!!?????
Hey DiabGeeks - this 👇🏼looks like it will be an extraordinary tool to add to the diabetes researcher armoury 🧪🔬
Congratulations 🚀🙌🏼
#devbio
Hope it flies!
Congratulations 🚀🙌🏼
#devbio
Hope it flies!
Happy to share our work on pancreatic ductal organoids from the human-relevant pig model across developmental stages ranging from embryonic to adult animals and using them for drug screening applications from the @heikolickert.bsky.social lab. #PancSky #devbio 🧪🧬 www.biorxiv.org/content/10.1... /1
Benchmarking porcine pancreatic ductal organoids for drug screening applications
Primary human pancreatic ductal organoids (HPDO) have emerged as a model to study pancreas biology and disease. Yet, donor material availability, and a lack of extensive benchmarking limits the range ...
www.biorxiv.org
March 15, 2025 at 9:02 PM
Hey DiabGeeks - this 👇🏼looks like it will be an extraordinary tool to add to the diabetes researcher armoury 🧪🔬
Congratulations 🚀🙌🏼
#devbio
Hope it flies!
Congratulations 🚀🙌🏼
#devbio
Hope it flies!
@breakthrought1duk.bsky.social Looking forward to saying hello!
March 8, 2025 at 8:47 PM
@breakthrought1duk.bsky.social Looking forward to saying hello!
Reposted by Pia Leete
Hugely excited to share a truly cross-disciplinary project examining human #islet_architecture in health&in #type_1_diabetes #T1D: combining #machine_learning, elegant #mathematical_modelling in whole section, fixed pancreatic samples stained for all 5 islet hormones:
1/2
🧪🔬🚀
doi.org/10.1007/s001...
1/2
🧪🔬🚀
doi.org/10.1007/s001...
Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes - Diabetologia
Aims/hypothesis The organisation and cellular architecture of islets of Langerhans are critical to the physiological regulation of hormone secretion but it is debated whether human islets adhere to th...
doi.org
February 27, 2025 at 2:49 PM
Hugely excited to share a truly cross-disciplinary project examining human #islet_architecture in health&in #type_1_diabetes #T1D: combining #machine_learning, elegant #mathematical_modelling in whole section, fixed pancreatic samples stained for all 5 islet hormones:
1/2
🧪🔬🚀
doi.org/10.1007/s001...
1/2
🧪🔬🚀
doi.org/10.1007/s001...
Reposted by Pia Leete
I purchased a microscope I really like last August: 300k machine.
Today I learned that support for windows 10 machines is ending and we will have to upgrade to windows 11.
Company is asking for 11K for an “upgrade kit”.
Wanna prevent waste of taxpayer money?
This is predatory.
Today I learned that support for windows 10 machines is ending and we will have to upgrade to windows 11.
Company is asking for 11K for an “upgrade kit”.
Wanna prevent waste of taxpayer money?
This is predatory.
a man wearing a shirt that says it 's not fine on it
ALT: a man wearing a shirt that says it 's not fine on it
media.tenor.com
February 28, 2025 at 12:38 AM
I purchased a microscope I really like last August: 300k machine.
Today I learned that support for windows 10 machines is ending and we will have to upgrade to windows 11.
Company is asking for 11K for an “upgrade kit”.
Wanna prevent waste of taxpayer money?
This is predatory.
Today I learned that support for windows 10 machines is ending and we will have to upgrade to windows 11.
Company is asking for 11K for an “upgrade kit”.
Wanna prevent waste of taxpayer money?
This is predatory.
Hugely excited to share a truly cross-disciplinary project examining human #islet_architecture in health&in #type_1_diabetes #T1D: combining #machine_learning, elegant #mathematical_modelling in whole section, fixed pancreatic samples stained for all 5 islet hormones:
1/2
🧪🔬🚀
doi.org/10.1007/s001...
1/2
🧪🔬🚀
doi.org/10.1007/s001...
Beyond the loss of beta cells: a quantitative analysis of islet architecture in adults with and without type 1 diabetes - Diabetologia
Aims/hypothesis The organisation and cellular architecture of islets of Langerhans are critical to the physiological regulation of hormone secretion but it is debated whether human islets adhere to th...
doi.org
February 27, 2025 at 2:49 PM
Hugely excited to share a truly cross-disciplinary project examining human #islet_architecture in health&in #type_1_diabetes #T1D: combining #machine_learning, elegant #mathematical_modelling in whole section, fixed pancreatic samples stained for all 5 islet hormones:
1/2
🧪🔬🚀
doi.org/10.1007/s001...
1/2
🧪🔬🚀
doi.org/10.1007/s001...
Oooh and more positive news … I believe we can curate our lives - and it starts with what we chase in the media… and social media! Isn’t that why we stepped away from “Ex”…
- you’re welcome! 🥰
- you’re welcome! 🥰
February 16, 2025 at 9:38 PM
Oooh and more positive news … I believe we can curate our lives - and it starts with what we chase in the media… and social media! Isn’t that why we stepped away from “Ex”…
- you’re welcome! 🥰
- you’re welcome! 🥰
Grist to the mill ….
Work from a great team, excellent use of tech, and beautifully written! Great paper - really enjoyed it!
🔬🧪🚀 #beta_cells #islet_architecture #diabetes_research #creative_science
Work from a great team, excellent use of tech, and beautifully written! Great paper - really enjoyed it!
🔬🧪🚀 #beta_cells #islet_architecture #diabetes_research #creative_science
Leading the pack: Glucokinase reinforces Ca2+-waves
#PancSky #BetaCellSky
elifesciences.org/articles/103...
#PancSky #BetaCellSky
elifesciences.org/articles/103...
Glucokinase activity controls peripherally located subpopulations of β-cells that lead islet Ca2+ oscillations
3D light-sheet imaging identifies the location and metabolic sensitivity of β-cell subpopulations that lead and coordinate islet Ca2+ oscillations.
elifesciences.org
February 14, 2025 at 6:23 AM
Grist to the mill ….
Work from a great team, excellent use of tech, and beautifully written! Great paper - really enjoyed it!
🔬🧪🚀 #beta_cells #islet_architecture #diabetes_research #creative_science
Work from a great team, excellent use of tech, and beautifully written! Great paper - really enjoyed it!
🔬🧪🚀 #beta_cells #islet_architecture #diabetes_research #creative_science
Many of you who know me are familiar with my abiding belief that the right food can help just about anything:
This work is a shocking indictment of progressive failures which, of course, are complex; but may also be a pretty good beginning for more visibility of the problem #health #responsibility🙏🏼
This work is a shocking indictment of progressive failures which, of course, are complex; but may also be a pretty good beginning for more visibility of the problem #health #responsibility🙏🏼
(1)
The @foodfoundation.bsky.social's The Broken Plate 2025 report is out! @mrcepid.bsky.social researchers @thomasburgoine.bsky.social, @jhoenink.bsky.social, & @jeanmadams.bsky.social contributed to it, finding the gap is widening between the cost of more & less healthy foods.
buff.ly/42zECIJ
The @foodfoundation.bsky.social's The Broken Plate 2025 report is out! @mrcepid.bsky.social researchers @thomasburgoine.bsky.social, @jhoenink.bsky.social, & @jeanmadams.bsky.social contributed to it, finding the gap is widening between the cost of more & less healthy foods.
buff.ly/42zECIJ
Unit researchers contribute to the Food Foundation Broken Plate 2025 report - MRC Epidemiology Unit
The Broken Plate Report 2025 has found that too many people in the UK do not have the finances to access healthy, quality food. The report also evidences the fact […]
www.mrc-epid.cam.ac.uk
February 4, 2025 at 9:47 PM
Many of you who know me are familiar with my abiding belief that the right food can help just about anything:
This work is a shocking indictment of progressive failures which, of course, are complex; but may also be a pretty good beginning for more visibility of the problem #health #responsibility🙏🏼
This work is a shocking indictment of progressive failures which, of course, are complex; but may also be a pretty good beginning for more visibility of the problem #health #responsibility🙏🏼
Wow:
just very very cool.
just very very cool.
Not only does Bennu contain all 5 of the nucleobases that form DNA and RNA on Earth and 14 of the 20 amino acids found in known proteins, the asteroid’s amino acids hold a surprise
https://go.nature.com/4hDJnFM
https://go.nature.com/4hDJnFM
Asteroid fragments upend theory of how life on Earth bloomed
Nature - Samples from Bennu contain the chemical building blocks of life — but with a twist.
go.nature.com
February 1, 2025 at 12:54 PM
Wow:
just very very cool.
just very very cool.
Sorry - I know this is a place for exciting science - but in a world that increasingly needs hope… there is this image …🙏🏼❤️🙏🏼🩷💪🏼🫵🏼
Meanwhile mass demonstrations across Germany against Trump, Merz and the AfD.
Danke, Deutschland.
emea01.safelinks.protection.outlook.com?url=https%3A...
Danke, Deutschland.
emea01.safelinks.protection.outlook.com?url=https%3A...
Zehntausende demonstrieren gegen Trump, Merz und AfD
In mehreren Städten rufen Bündnisse zu Protesten gegen Rechts auf. In Köln kommen nach Polizeiangaben etwa 40.000 Menschen zusammen, in Berlin sind es mehr als 30.000. Sie wenden sich auch gegen Pläne...
emea01.safelinks.protection.outlook.com
January 25, 2025 at 10:54 PM
Sorry - I know this is a place for exciting science - but in a world that increasingly needs hope… there is this image …🙏🏼❤️🙏🏼🩷💪🏼🫵🏼
What a lovely feature… where does 🙏🏼take you? Or 💞?
Not that 🚀🧪🔬isn’t super cool!
Not that 🚀🧪🔬isn’t super cool!
So many new #BluSci users 💙✨❄️, welcome!
For science-minded folks, there are some very cool tricks 🚀…
use 🧪 to post on the #Science feed
use 🧠 for a #Neuroskyence feed
If you use any of these emojis👩🔬|👩🏻🔬|👩🏼🔬|👩🏽🔬|👩🏾🔬|👩🏿🔬 your post will on a #WomenInSTEM feed
Bonuses: 🕊️ 🌱 📌
Go get it 🚀🧪🧠👩🔬💙
For science-minded folks, there are some very cool tricks 🚀…
use 🧪 to post on the #Science feed
use 🧠 for a #Neuroskyence feed
If you use any of these emojis👩🔬|👩🏻🔬|👩🏼🔬|👩🏽🔬|👩🏾🔬|👩🏿🔬 your post will on a #WomenInSTEM feed
Bonuses: 🕊️ 🌱 📌
Go get it 🚀🧪🧠👩🔬💙
January 24, 2025 at 10:14 PM
What a lovely feature… where does 🙏🏼take you? Or 💞?
Not that 🚀🧪🔬isn’t super cool!
Not that 🚀🧪🔬isn’t super cool!