Raghunath M
@raghumnephdoc.bsky.social
Kidney doc from God's own country (thats Kerala, in India) here!
Music, movies, books, plants, cats and dogs.
Music, movies, books, plants, cats and dogs.
Reposted by Raghunath M
🧵 New #Skeetorial Drop! 🧵
1/ Hey #NephSky! 👋
We’re back with a fresh #Skeetorial from @kireports.bsky.social , this time diving into:
Dapagliflozin in Stage 4 CKD: no diabetes required? 🤔
Let’s unpack what this trial means for your next CKD patient. 💊💭
1/ Hey #NephSky! 👋
We’re back with a fresh #Skeetorial from @kireports.bsky.social , this time diving into:
Dapagliflozin in Stage 4 CKD: no diabetes required? 🤔
Let’s unpack what this trial means for your next CKD patient. 💊💭
November 20, 2025 at 6:47 PM
🧵 New #Skeetorial Drop! 🧵
1/ Hey #NephSky! 👋
We’re back with a fresh #Skeetorial from @kireports.bsky.social , this time diving into:
Dapagliflozin in Stage 4 CKD: no diabetes required? 🤔
Let’s unpack what this trial means for your next CKD patient. 💊💭
1/ Hey #NephSky! 👋
We’re back with a fresh #Skeetorial from @kireports.bsky.social , this time diving into:
Dapagliflozin in Stage 4 CKD: no diabetes required? 🤔
Let’s unpack what this trial means for your next CKD patient. 💊💭
Reposted by Raghunath M
The most helpful phrase of 2025 👇
November 13, 2025 at 3:24 PM
The most helpful phrase of 2025 👇
#eveningrun @sreejithdr.bsky.social inspired by your runs😀
November 14, 2025 at 12:33 PM
#eveningrun @sreejithdr.bsky.social inspired by your runs😀
Was listening to nephjc freely filtered episode of ACHIEVE trial just the other day. Of all the things we've tried in HD and failed, and now fish oil does the trick??? @kidneyboy.bsky.social @hswapnil.medsky.social
Shocking first high impact trial of the day. Fish oil reduces CV events in dialysis patients! #Pisces #kidneywk
Simultaneous pub in NEJM
www.nejm.org/doi/full/10....
Simultaneous pub in NEJM
www.nejm.org/doi/full/10....
November 7, 2025 at 11:40 PM
Was listening to nephjc freely filtered episode of ACHIEVE trial just the other day. Of all the things we've tried in HD and failed, and now fish oil does the trick??? @kidneyboy.bsky.social @hswapnil.medsky.social
Reposted by Raghunath M
Trying to catch up with IgA Nephropathy trials⁉️
Check out ✅ “IgAN: An Overview of the Clinical Trials” ca. 2025 from @kidneymed.bsky.social @alexgr23.bsky.social @saynanorouzi.bsky.social
#Nephpearls #NephSky #KidneyWk #IgAN
👉 pubmed.ncbi.nlm.nih.gov/41050133/
Check out ✅ “IgAN: An Overview of the Clinical Trials” ca. 2025 from @kidneymed.bsky.social @alexgr23.bsky.social @saynanorouzi.bsky.social
#Nephpearls #NephSky #KidneyWk #IgAN
👉 pubmed.ncbi.nlm.nih.gov/41050133/
November 5, 2025 at 2:17 PM
Trying to catch up with IgA Nephropathy trials⁉️
Check out ✅ “IgAN: An Overview of the Clinical Trials” ca. 2025 from @kidneymed.bsky.social @alexgr23.bsky.social @saynanorouzi.bsky.social
#Nephpearls #NephSky #KidneyWk #IgAN
👉 pubmed.ncbi.nlm.nih.gov/41050133/
Check out ✅ “IgAN: An Overview of the Clinical Trials” ca. 2025 from @kidneymed.bsky.social @alexgr23.bsky.social @saynanorouzi.bsky.social
#Nephpearls #NephSky #KidneyWk #IgAN
👉 pubmed.ncbi.nlm.nih.gov/41050133/
acrobat.adobe.com/id/urn:aaid:...
finerenone vs spiro - a trial emulation
Would love to know your thoughts on this paper @hswapnil.medsky.social
finerenone vs spiro - a trial emulation
Would love to know your thoughts on this paper @hswapnil.medsky.social
Adobe Acrobat
acrobat.adobe.com
November 3, 2025 at 2:15 AM
acrobat.adobe.com/id/urn:aaid:...
finerenone vs spiro - a trial emulation
Would love to know your thoughts on this paper @hswapnil.medsky.social
finerenone vs spiro - a trial emulation
Would love to know your thoughts on this paper @hswapnil.medsky.social
Reposted by Raghunath M
How do mRNA vaccines help fight cancer?
A @nature.com paper today tells the story, one with big implications, as reviewed here
erictopol.substack.com/p/how-mrna-v...
A @nature.com paper today tells the story, one with big implications, as reviewed here
erictopol.substack.com/p/how-mrna-v...
How mRNA Vaccines Can Help Fight Cancer
Turning "cold" tumors "hot"
erictopol.substack.com
October 22, 2025 at 3:19 PM
How do mRNA vaccines help fight cancer?
A @nature.com paper today tells the story, one with big implications, as reviewed here
erictopol.substack.com/p/how-mrna-v...
A @nature.com paper today tells the story, one with big implications, as reviewed here
erictopol.substack.com/p/how-mrna-v...
Reposted by Raghunath M
Useful guidance for bashing reviewers in the face when they talk beyond their expertise.
Determining sample size for pilot trials: a tutorial
www.bmj.com/content/bmj/...
Determining sample size for pilot trials: a tutorial
www.bmj.com/content/bmj/...
www.bmj.com
August 18, 2025 at 12:20 PM
Useful guidance for bashing reviewers in the face when they talk beyond their expertise.
Determining sample size for pilot trials: a tutorial
www.bmj.com/content/bmj/...
Determining sample size for pilot trials: a tutorial
www.bmj.com/content/bmj/...
Reposted by Raghunath M
Acanthocyte - phase contrast (original mag x400) - from patient with hydralazine-induced vasculitis #UrineMicroscopy #UrinarySediment
August 16, 2025 at 1:53 AM
Acanthocyte - phase contrast (original mag x400) - from patient with hydralazine-induced vasculitis #UrineMicroscopy #UrinarySediment
1/2 They say MEST scoring shouldn't inform Rx decisions. But it does, doesn't it? Witha high M/E score you would like to give strong antinflamm rx; you would think twice about giving steroid/mmf with S1/T2 score. So it does influence your choice in a way.
#nephsky
#nephsky
August 15, 2025 at 12:36 PM
1/2 They say MEST scoring shouldn't inform Rx decisions. But it does, doesn't it? Witha high M/E score you would like to give strong antinflamm rx; you would think twice about giving steroid/mmf with S1/T2 score. So it does influence your choice in a way.
#nephsky
#nephsky
Can someone make sense of this figure? It's from the nephjc article on EMPAKIDNEY followup trial. Does this mean that the longer you remain on sglt2is, the benifit wanes over time? Am I reading that right? #nephsky
July 28, 2025 at 4:02 AM
Can someone make sense of this figure? It's from the nephjc article on EMPAKIDNEY followup trial. Does this mean that the longer you remain on sglt2is, the benifit wanes over time? Am I reading that right? #nephsky
When even movie script writers reach for hydralazine so fast, nephrologists don't stand a chance! @hswapnil.medsky.social
@kidneyboy.bsky.social
@kidneyboy.bsky.social
July 26, 2025 at 4:03 PM
When even movie script writers reach for hydralazine so fast, nephrologists don't stand a chance! @hswapnil.medsky.social
@kidneyboy.bsky.social
@kidneyboy.bsky.social
Reposted by Raghunath M
1/ July 16 is #WorldSnakeDay - raising awareness of the incredible diversity of snakes and their vital role in our ecosystems. But did you know snakebites can also cause acute kidney injury? Join me, Dr. Fong Voon Ken, as we discuss their impact, management, and the need for awareness.
July 16, 2025 at 1:55 PM
1/ July 16 is #WorldSnakeDay - raising awareness of the incredible diversity of snakes and their vital role in our ecosystems. But did you know snakebites can also cause acute kidney injury? Join me, Dr. Fong Voon Ken, as we discuss their impact, management, and the need for awareness.
Reposted by Raghunath M
SGLT2i in CKD: impact beyond kidneys
🔻 15% all-cause hospitalizations
✅ Consistent regardless of eGFR, UACR & diabetes
🏥 ~36 fewer hospitalizations per 1000 pt-years
Large absolute gains for patients & health systems
Meta-analysis in @asnpublications.bsky.social
journals.lww.com/cjasn/pages/...
🔻 15% all-cause hospitalizations
✅ Consistent regardless of eGFR, UACR & diabetes
🏥 ~36 fewer hospitalizations per 1000 pt-years
Large absolute gains for patients & health systems
Meta-analysis in @asnpublications.bsky.social
journals.lww.com/cjasn/pages/...
July 15, 2025 at 3:40 AM
SGLT2i in CKD: impact beyond kidneys
🔻 15% all-cause hospitalizations
✅ Consistent regardless of eGFR, UACR & diabetes
🏥 ~36 fewer hospitalizations per 1000 pt-years
Large absolute gains for patients & health systems
Meta-analysis in @asnpublications.bsky.social
journals.lww.com/cjasn/pages/...
🔻 15% all-cause hospitalizations
✅ Consistent regardless of eGFR, UACR & diabetes
🏥 ~36 fewer hospitalizations per 1000 pt-years
Large absolute gains for patients & health systems
Meta-analysis in @asnpublications.bsky.social
journals.lww.com/cjasn/pages/...
@nephjc.bsky.social
#nephjc Raghunath, nephrologist from Kerala, India. No COI. Mostly lurking and learning.
#nephjc Raghunath, nephrologist from Kerala, India. No COI. Mostly lurking and learning.
July 9, 2025 at 1:08 AM
@nephjc.bsky.social
#nephjc Raghunath, nephrologist from Kerala, India. No COI. Mostly lurking and learning.
#nephjc Raghunath, nephrologist from Kerala, India. No COI. Mostly lurking and learning.
#nephsky Hi! What do you guys would work best in a patient with bx proven IC-MPGN? Nephrotic synd + creat 2. Workup for paraprotein, infection and autoimmune ds negative.
Rtx or CNI or MMF?
Rtx or CNI or MMF?
July 3, 2025 at 1:15 AM
#nephsky Hi! What do you guys would work best in a patient with bx proven IC-MPGN? Nephrotic synd + creat 2. Workup for paraprotein, infection and autoimmune ds negative.
Rtx or CNI or MMF?
Rtx or CNI or MMF?
Reposted by Raghunath M
Check out this from Dr Meghan Sise #NephGR for us on the topic
youtu.be/qFYVhjpnYIU?...
#OncoNeph #NephSky
youtu.be/qFYVhjpnYIU?...
#OncoNeph #NephSky
June 27, 2025 at 1:36 PM
Check out this from Dr Meghan Sise #NephGR for us on the topic
youtu.be/qFYVhjpnYIU?...
#OncoNeph #NephSky
youtu.be/qFYVhjpnYIU?...
#OncoNeph #NephSky
Reposted by Raghunath M
A 7-year-old lioness reunites with the man who raised her after she was abandoned as a cub 🦁❤️ He slept beside her outside so she'd grow up as naturally as possible. Now she tackles him with love-hugs, face rubs, pure joy-until they collapse in a pile of trust. 🫶 #WildBond #HeartmeltingNature
June 18, 2025 at 9:18 PM
A 7-year-old lioness reunites with the man who raised her after she was abandoned as a cub 🦁❤️ He slept beside her outside so she'd grow up as naturally as possible. Now she tackles him with love-hugs, face rubs, pure joy-until they collapse in a pile of trust. 🫶 #WildBond #HeartmeltingNature
#nephsky query!
When you have ⬆️K, is there a rule as to how much aldo should rise? i hv a pt with K consistently around 5.5 and aldo level 14.2ng/dl, DRC 1.33mIU/ml, would you say that the aldo is inappropriately nrml & this is hyporeninemic hypoaldo?
@kidneyboy.bsky.social @hswapnil.medsky.social
When you have ⬆️K, is there a rule as to how much aldo should rise? i hv a pt with K consistently around 5.5 and aldo level 14.2ng/dl, DRC 1.33mIU/ml, would you say that the aldo is inappropriately nrml & this is hyporeninemic hypoaldo?
@kidneyboy.bsky.social @hswapnil.medsky.social
June 11, 2025 at 3:55 PM
#nephsky query!
When you have ⬆️K, is there a rule as to how much aldo should rise? i hv a pt with K consistently around 5.5 and aldo level 14.2ng/dl, DRC 1.33mIU/ml, would you say that the aldo is inappropriately nrml & this is hyporeninemic hypoaldo?
@kidneyboy.bsky.social @hswapnil.medsky.social
When you have ⬆️K, is there a rule as to how much aldo should rise? i hv a pt with K consistently around 5.5 and aldo level 14.2ng/dl, DRC 1.33mIU/ml, would you say that the aldo is inappropriately nrml & this is hyporeninemic hypoaldo?
@kidneyboy.bsky.social @hswapnil.medsky.social