MitoStarsLab
@richterlab.bsky.social
We are dedicated to improving the life of patients with mitochondrial disease by understanding the mechanisms that underlie their untreatable maladies.
https://www.ncl.ac.uk/nuact/fellows/profiles/uwerichter/
https://www.ncl.ac.uk/nuact/fellows/profiles/uwerichter/
Reposted by MitoStarsLab
The days of Google Docs are ending; we enter the age of Docs, made by France's Interministerial Directorate for Digital Affairs and Germany's Center for Digital Sovereignty of Public Administration.
We need more governments to collaborate on public software projects to achieve digital sovereignty.
We need more governments to collaborate on public software projects to achieve digital sovereignty.
France and Germany unveil Docs, a homegrown alternative to Google Docs
The Trump administration has set out to drastically reshape the relationship between the US and Europe. In response, Brussels is scrambling to adapt to this new reality,...
www.techspot.com
April 21, 2025 at 2:25 PM
The days of Google Docs are ending; we enter the age of Docs, made by France's Interministerial Directorate for Digital Affairs and Germany's Center for Digital Sovereignty of Public Administration.
We need more governments to collaborate on public software projects to achieve digital sovereignty.
We need more governments to collaborate on public software projects to achieve digital sovereignty.
Application deadline approaching fast! If you are a PhD student or a postdoc register for this summer school in the happiest country in the world. Amazing program, amazing people, amazing place! ssl.eventilla.com/mitochondria...
Mitochondria Summer School
ssl.eventilla.com
April 9, 2025 at 6:51 AM
Application deadline approaching fast! If you are a PhD student or a postdoc register for this summer school in the happiest country in the world. Amazing program, amazing people, amazing place! ssl.eventilla.com/mitochondria...
Reposted by MitoStarsLab
Join this event for PhD students and postdocs in the amazing wilderness of Northern Finland! Reg. dl Thu 10th Apr. Spa hotel Rokua with plenty of saunas and pools and other fun. 😎 Network and learn about mitochondria! @mitoworld.bsky.social @richterlab.bsky.social @ki.se @cecad.bsky.social
Mitochondria Summer School
ssl.eventilla.com
April 7, 2025 at 8:05 AM
Join this event for PhD students and postdocs in the amazing wilderness of Northern Finland! Reg. dl Thu 10th Apr. Spa hotel Rokua with plenty of saunas and pools and other fun. 😎 Network and learn about mitochondria! @mitoworld.bsky.social @richterlab.bsky.social @ki.se @cecad.bsky.social
Reposted by MitoStarsLab
Lots of excellent advice in this piece. The core message - only through writing do you really think and order your thoughts into logical sense. Makes a case for not using AI for 1st draft because you bypass the thinking step
www.nature.com/articles/s41...
@naturebiotech.bsky.social
#PlantScience
www.nature.com/articles/s41...
@naturebiotech.bsky.social
#PlantScience
An open letter to graduate students and other procrastinators: it’s time to write - Nature Biotechnology
Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write
www.nature.com
April 5, 2025 at 8:40 AM
Lots of excellent advice in this piece. The core message - only through writing do you really think and order your thoughts into logical sense. Makes a case for not using AI for 1st draft because you bypass the thinking step
www.nature.com/articles/s41...
@naturebiotech.bsky.social
#PlantScience
www.nature.com/articles/s41...
@naturebiotech.bsky.social
#PlantScience
Reposted by MitoStarsLab
The coming age of causality will be a rebellion against the correlation weirdos
March 28, 2025 at 7:16 AM
The coming age of causality will be a rebellion against the correlation weirdos
Reposted by MitoStarsLab
Combining bacterial end joining with programmable nucleases, we induced mtDNA deletions in human cells at varying heteroplasmy and examined their metabolic and cellular effects. Simple tool to apply across any cell type and engineer pathogenic mtDNA deletions. www.sciencedirect.com/science/arti...
Engineering mtDNA deletions by reconstituting end joining in human mitochondria
Recent breakthroughs in the genetic manipulation of mitochondrial DNA (mtDNA) have enabled precise base substitutions and the efficient elimination of…
www.sciencedirect.com
March 10, 2025 at 6:38 PM
Combining bacterial end joining with programmable nucleases, we induced mtDNA deletions in human cells at varying heteroplasmy and examined their metabolic and cellular effects. Simple tool to apply across any cell type and engineer pathogenic mtDNA deletions. www.sciencedirect.com/science/arti...
🍾Bursting with pride and joy! Watching you grow as a scientist and individual has been incredible. Congrats, Jon, on truly earning your 🎓PhD! Thanks to all the amazing support @taylorlabncl.bsky.social
@cgm-newcastle.bsky.social
@mitonewcastle.bsky.social and examiners Ray O’Keefe and Tom Nicholls!
@cgm-newcastle.bsky.social
@mitonewcastle.bsky.social and examiners Ray O’Keefe and Tom Nicholls!
March 2, 2025 at 11:42 AM
🍾Bursting with pride and joy! Watching you grow as a scientist and individual has been incredible. Congrats, Jon, on truly earning your 🎓PhD! Thanks to all the amazing support @taylorlabncl.bsky.social
@cgm-newcastle.bsky.social
@mitonewcastle.bsky.social and examiners Ray O’Keefe and Tom Nicholls!
@cgm-newcastle.bsky.social
@mitonewcastle.bsky.social and examiners Ray O’Keefe and Tom Nicholls!
Reposted by MitoStarsLab
My recent podcast with Francis. What he has done to advance biomedicine in the US and globally is immeasurable.
erictopol.substack.com/p/francis-co...
erictopol.substack.com/p/francis-co...
Francis Collins: On Truth, Science, Faith and Trust
Listen now (40 mins) | A very personal story—his inspiring new book THE ROAD TO WISDOM—and other closely related matters
erictopol.substack.com
March 1, 2025 at 7:05 PM
My recent podcast with Francis. What he has done to advance biomedicine in the US and globally is immeasurable.
erictopol.substack.com/p/francis-co...
erictopol.substack.com/p/francis-co...
Pleased to see @cgm-newcastle.bsky.social and @taylorlabncl.bsky.social have joined us here
March 1, 2025 at 10:50 AM
Pleased to see @cgm-newcastle.bsky.social and @taylorlabncl.bsky.social have joined us here
Reposted by MitoStarsLab
Mysterious increase in the motility of these #lysosomes
After adding a non-stimuli treatment the lysosomes (cyan) got crazy (see color coded tracks)
Maybe #mechanosignaling triggered by shear stress?
#Microscopy + #Cells for #FluorescenceFriday 🧪🔬
#SciSky #scicomm #CellBio
After adding a non-stimuli treatment the lysosomes (cyan) got crazy (see color coded tracks)
Maybe #mechanosignaling triggered by shear stress?
#Microscopy + #Cells for #FluorescenceFriday 🧪🔬
#SciSky #scicomm #CellBio
February 14, 2025 at 7:38 AM
Mysterious increase in the motility of these #lysosomes
After adding a non-stimuli treatment the lysosomes (cyan) got crazy (see color coded tracks)
Maybe #mechanosignaling triggered by shear stress?
#Microscopy + #Cells for #FluorescenceFriday 🧪🔬
#SciSky #scicomm #CellBio
After adding a non-stimuli treatment the lysosomes (cyan) got crazy (see color coded tracks)
Maybe #mechanosignaling triggered by shear stress?
#Microscopy + #Cells for #FluorescenceFriday 🧪🔬
#SciSky #scicomm #CellBio
Reposted by MitoStarsLab
Congrats to Dr. Ana Andjelković from our and @richterlab.bsky.social lab for winning 2nd place in the Huygens Image Contest! 🎉🏆 Live STED imaging shows the cristae dynamics in a pathophysiological condition. svi.nl/imagecontest... #ScienceArt #ImageContest
January 31, 2025 at 1:57 PM
Congrats to Dr. Ana Andjelković from our and @richterlab.bsky.social lab for winning 2nd place in the Huygens Image Contest! 🎉🏆 Live STED imaging shows the cristae dynamics in a pathophysiological condition. svi.nl/imagecontest... #ScienceArt #ImageContest
Reposted by MitoStarsLab
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
doi.org
November 25, 2024 at 11:16 AM
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Reposted by MitoStarsLab
How long does an mRNA stay in the nucleus? How long does it stay in the cytoplasm? In an amazing collaboration with @landthalerm.bsky.social, we used metabolic labeling, cell fractionation and mathematical modeling to quantify mRNA flow through the cell. Finally out in MSB: doi.org/10.1038/s443...
November 21, 2024 at 2:56 PM
How long does an mRNA stay in the nucleus? How long does it stay in the cytoplasm? In an amazing collaboration with @landthalerm.bsky.social, we used metabolic labeling, cell fractionation and mathematical modeling to quantify mRNA flow through the cell. Finally out in MSB: doi.org/10.1038/s443...
Reposted by MitoStarsLab
My first post!
#mRNA translation initiation and its regulation in eukaryotes.
#Ribosomes #cryoEM #RNABiology #Translation #Science
#mRNA translation initiation and its regulation in eukaryotes.
#Ribosomes #cryoEM #RNABiology #Translation #Science
November 19, 2024 at 2:30 AM
My first post!
#mRNA translation initiation and its regulation in eukaryotes.
#Ribosomes #cryoEM #RNABiology #Translation #Science
#mRNA translation initiation and its regulation in eukaryotes.
#Ribosomes #cryoEM #RNABiology #Translation #Science
Reposted by MitoStarsLab
Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice https://www.biorxiv.org/content/10.1101/2024.11.14.623694v1
Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice https://www.biorxiv.org/content/10.1101/2024.11.14.623694v1
Somatic mitochondrial DNA (mtDNA) mutations are heavily implicated as important drivers of ageing an
www.biorxiv.org
November 18, 2024 at 2:33 PM
Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice https://www.biorxiv.org/content/10.1101/2024.11.14.623694v1
Reposted by MitoStarsLab
The human mitochondrial ClpXP is uniquely assembled and regulated compared to its bacterial counterparts. Congrats to Kelly Chen on her years of hard work on this challenging complex!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 14, 2024 at 3:19 PM
The human mitochondrial ClpXP is uniquely assembled and regulated compared to its bacterial counterparts. Congrats to Kelly Chen on her years of hard work on this challenging complex!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by MitoStarsLab
Happy to have my first post on this site be to share the news that our amazing student Alia will be presenting her work on mitochondrial fission at MitoChats Thursday (10am US central time)! Be sure to check it out!
MITOtalks have not made it here (yet) but we are excited to host two fantastic trainee talks this week on MITOchats - Alia Edington from Friedman lab at UTSW and David Eberhardt from Chaudhuri at UUtah - visit www.mitotalks.org for more info and zoom link to join! #mitochondria please share!
November 12, 2024 at 7:36 PM
Happy to have my first post on this site be to share the news that our amazing student Alia will be presenting her work on mitochondrial fission at MitoChats Thursday (10am US central time)! Be sure to check it out!
Reposted by MitoStarsLab
[looking at Bluesky over the past 2 days] So this is what the Cambrian explosion must have felt like
November 11, 2024 at 10:17 PM
[looking at Bluesky over the past 2 days] So this is what the Cambrian explosion must have felt like
Reposted by MitoStarsLab
Breaking down #Alzheimers disease into 5 subtypes by proteins in cerebrospinal fluid, with distinct genomic profiles and molecular processes nature.com/articles/s43...
January 10, 2024 at 1:54 AM
Breaking down #Alzheimers disease into 5 subtypes by proteins in cerebrospinal fluid, with distinct genomic profiles and molecular processes nature.com/articles/s43...
Reposted by MitoStarsLab
Uber: we can't make money if we have to follow the law
Google: we can't make money if we're not allowed to be a monopoly
Nestle: we can't make money without using slave labor
OpenAI: we can't make money if we can't steal
media: should shoplifters be executed?
Google: we can't make money if we're not allowed to be a monopoly
Nestle: we can't make money without using slave labor
OpenAI: we can't make money if we can't steal
media: should shoplifters be executed?
January 9, 2024 at 2:18 PM
Uber: we can't make money if we have to follow the law
Google: we can't make money if we're not allowed to be a monopoly
Nestle: we can't make money without using slave labor
OpenAI: we can't make money if we can't steal
media: should shoplifters be executed?
Google: we can't make money if we're not allowed to be a monopoly
Nestle: we can't make money without using slave labor
OpenAI: we can't make money if we can't steal
media: should shoplifters be executed?
Reposted by MitoStarsLab
I can’t even fathom how clueless a person would need to be to say this out loud.
Open any history book, any corporate lawsuit and see how far you can trust humans in the face of greed. And *especially* institutions where people are “just doing their job”.
Open any history book, any corporate lawsuit and see how far you can trust humans in the face of greed. And *especially* institutions where people are “just doing their job”.
January 2, 2024 at 12:09 AM
I can’t even fathom how clueless a person would need to be to say this out loud.
Open any history book, any corporate lawsuit and see how far you can trust humans in the face of greed. And *especially* institutions where people are “just doing their job”.
Open any history book, any corporate lawsuit and see how far you can trust humans in the face of greed. And *especially* institutions where people are “just doing their job”.