CellComM Lab
@cellcommlab.bsky.social
𝗖𝗲𝗹𝗹 𝗖𝗼𝗺𝘮𝘶𝘯𝘪𝘤𝘢𝘵𝘪𝘰𝘯 & 𝗠𝘪𝘨𝘳𝘢𝘵𝘪𝘰𝘯 Lab, headed by
@pjsaez.bsky.social #UKE_HH
We ❤ #CellComm #CellMigration 🧪🔬 tinyurl.com/5n8sss49
@pjsaez.bsky.social #UKE_HH
We ❤ #CellComm #CellMigration 🧪🔬 tinyurl.com/5n8sss49
Pinned
CellComM Lab
@cellcommlab.bsky.social
· Jan 24
#CellMigration for #FluorescenceFriday 🧪🔬
If a metastatic #cancer cell is offered 2 paths it decides very fast, bc it does matter where it goes...
OTOH, if a non-cancer #cell is offered 2 options it takes some time to explore and decide.
More in the paper: www.nature.com/articles/s41...
If a metastatic #cancer cell is offered 2 paths it decides very fast, bc it does matter where it goes...
OTOH, if a non-cancer #cell is offered 2 options it takes some time to explore and decide.
More in the paper: www.nature.com/articles/s41...
Reposted by CellComM Lab
Hot from the #preprint
Leukocyte + #CellMigration + physics = cool
Microtubules enable torque-based steering during dendritic cell migration.
Actomyosin contractility is required for noise-modulation strategy used by neutrophils.
Full @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
Leukocyte + #CellMigration + physics = cool
Microtubules enable torque-based steering during dendritic cell migration.
Actomyosin contractility is required for noise-modulation strategy used by neutrophils.
Full @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
Torque-based immune cell chemotaxis in complex environments
Directed migration in chemical gradients is crucial to the immune response, yet how immune cells navigate complex tissues remains incompletely understood. Using in vitro migration assays and theoretic...
www.biorxiv.org
November 23, 2025 at 2:39 PM
Hot from the #preprint
Leukocyte + #CellMigration + physics = cool
Microtubules enable torque-based steering during dendritic cell migration.
Actomyosin contractility is required for noise-modulation strategy used by neutrophils.
Full @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
Leukocyte + #CellMigration + physics = cool
Microtubules enable torque-based steering during dendritic cell migration.
Actomyosin contractility is required for noise-modulation strategy used by neutrophils.
Full @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...
Reposted by CellComM Lab
Still posting cytoskeleton videos, it seems. Actin this time.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
November 23, 2025 at 3:21 AM
Still posting cytoskeleton videos, it seems. Actin this time.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Sample: Lifeact-eGFP in HeLa cells.
Modality: Airyscan confocal
Timestamp is mm:ss and the scale bar is 5 µm.
Reposted by CellComM Lab
It’s time to talk about epithelial geometry and cancer. How can the architecture of an epithelium affect how tumors will grow and spread? In this thread, @jorgealmagro.bsky.social
November 23, 2025 at 8:01 AM
It’s time to talk about epithelial geometry and cancer. How can the architecture of an epithelium affect how tumors will grow and spread? In this thread, @jorgealmagro.bsky.social
Reposted by CellComM Lab
Synchronized development of zebrafish embryos immobilized by snake venom (alpha-bungarotoxin). Credit to Dr. Ian Swinburne. #ZebrafishZunday
November 23, 2025 at 12:12 PM
Synchronized development of zebrafish embryos immobilized by snake venom (alpha-bungarotoxin). Credit to Dr. Ian Swinburne. #ZebrafishZunday
Reposted by CellComM Lab
Even if "provisionally" accepted, those are the best words/news I've heard for quite a while...
Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.
@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.
@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
November 21, 2025 at 2:55 PM
Even if "provisionally" accepted, those are the best words/news I've heard for quite a while...
Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.
@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
Here some #blebs to "provisionally" cellebrate.
Let's see this #cell dance under the microscope.
@focalplane.bsky.social #fluorescencefriday #microscopy 🧪🔬
Reposted by CellComM Lab
I'm back at regulardly doing some live imaging so I have new little videos of actin in the immune synapse.
November 21, 2025 at 2:17 PM
I'm back at regulardly doing some live imaging so I have new little videos of actin in the immune synapse.
Reposted by CellComM Lab
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
November 21, 2025 at 1:07 PM
The law of the jungle.
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Interactions of cells in a collective lead to global rotation.
In 80% of the case HUVEC cells turn clockwise.
How many cells does it take for this to happen?
Reposted by CellComM Lab
#AsgardArchaea team, led by @archaeal.bsky.social fr @texasscience.bsky.social — sequencing the DNA collected fr mouth of Rio de la Plata to the continental shelf of Uruguay to detect Asgards, a group of single-celled organisms & our closest microbial relatives on the tree of life. bit.ly/3MdniTH
November 21, 2025 at 12:07 AM
#AsgardArchaea team, led by @archaeal.bsky.social fr @texasscience.bsky.social — sequencing the DNA collected fr mouth of Rio de la Plata to the continental shelf of Uruguay to detect Asgards, a group of single-celled organisms & our closest microbial relatives on the tree of life. bit.ly/3MdniTH
Reposted by CellComM Lab
Do you want to do some frontier of knowledge research? There's still time to register for the next webinar of @hfspo.bsky.social
By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...
www.hfsp.org/hfsp-events/...
By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...
www.hfsp.org/hfsp-events/...
HFSP Webinar 2025: Research Grants | Human Frontier Science Program
www.hfsp.org
November 19, 2025 at 8:36 AM
Do you want to do some frontier of knowledge research? There's still time to register for the next webinar of @hfspo.bsky.social
By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...
www.hfsp.org/hfsp-events/...
By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...
www.hfsp.org/hfsp-events/...
Reposted by CellComM Lab
What a crazy cool paper! First author @pierreucla.bsky.social with a large crew knocked it out of the park. (GIF below from @the.3i.social LLS) Quantifying cell traction forces at the single-fiber scale in 3D: An approach based on deformable photopolymerized fiber arrays www.pnas.org/doi/10.1073/...
November 13, 2025 at 6:21 PM
What a crazy cool paper! First author @pierreucla.bsky.social with a large crew knocked it out of the park. (GIF below from @the.3i.social LLS) Quantifying cell traction forces at the single-fiber scale in 3D: An approach based on deformable photopolymerized fiber arrays www.pnas.org/doi/10.1073/...
Reposted by CellComM Lab
I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...
November 13, 2025 at 8:49 PM
I won't talk about NMeth @natmethods.nature.com forever (probably), but I do want to brag a bit about the November focus issue on cell segmentation and tracking, which is many ways is my last hurrah (and final editorial) for the journal. I am so proud of these papers!! www.nature.com/nmeth/volume...
Reposted by CellComM Lab
This week's #FluorescenceFriday, we'll be treated with one of the classical models of #devbio, the neural crest cells. Here is a beautiful video of neural crest cells with GFP-tagged focal adhesion kinase (🔵) and LifeAct-RFP (🟣) migrating on a Fibronectin matrix.
📹: Adam Shellard
📹: Adam Shellard
November 14, 2025 at 5:45 PM
This week's #FluorescenceFriday, we'll be treated with one of the classical models of #devbio, the neural crest cells. Here is a beautiful video of neural crest cells with GFP-tagged focal adhesion kinase (🔵) and LifeAct-RFP (🟣) migrating on a Fibronectin matrix.
📹: Adam Shellard
📹: Adam Shellard
Reposted by CellComM Lab
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
November 7, 2025 at 9:25 PM
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Reposted by CellComM Lab
Job alert!
We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?
See also on the forum:
forum.image.sc/t/research-e...
We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?
See also on the forum:
forum.image.sc/t/research-e...
Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA
Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...
forum.image.sc
October 7, 2025 at 12:39 PM
Job alert!
We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?
See also on the forum:
forum.image.sc/t/research-e...
We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?
See also on the forum:
forum.image.sc/t/research-e...
Reposted by CellComM Lab
🚨 My lab is hiring at all levels!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
October 8, 2025 at 5:49 PM
🚨 My lab is hiring at all levels!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Interested in animal origins & evolutionary cell biology?
I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics.
🔗: clarkelab.com/join/
Please repost!
Reposted by CellComM Lab
Interested in doing exciting research on #epithelial #plasticity in the #kidney or #intestine?
Then please check out our recent job ads for #PhD and #Postdoc positions!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Then please check out our recent job ads for #PhD and #Postdoc positions!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
September 9, 2025 at 4:49 PM
Interested in doing exciting research on #epithelial #plasticity in the #kidney or #intestine?
Then please check out our recent job ads for #PhD and #Postdoc positions!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Then please check out our recent job ads for #PhD and #Postdoc positions!
www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Reposted by CellComM Lab
I can't imagine a better day of the week to publish this than #FluorescenceFriday: PathoPlex is finally published! 🎉
This presents a revolutionary jump from 4-6 to 100+ markers per sample! 🤯
Read the full story here:
www.nature.com/articles/s41...
This presents a revolutionary jump from 4-6 to 100+ markers per sample! 🤯
Read the full story here:
www.nature.com/articles/s41...
July 18, 2025 at 1:24 PM
I can't imagine a better day of the week to publish this than #FluorescenceFriday: PathoPlex is finally published! 🎉
This presents a revolutionary jump from 4-6 to 100+ markers per sample! 🤯
Read the full story here:
www.nature.com/articles/s41...
This presents a revolutionary jump from 4-6 to 100+ markers per sample! 🤯
Read the full story here:
www.nature.com/articles/s41...
Reposted by CellComM Lab
#HotFromThePress !!
What if instead of analyzing 4-6 pathology markers you could check >100 in the *same* sample?
@maltekuehl.com & co @puellesv.bsky.social lab introduce #PathoPlex, method that could even predict disease
Full www.nature.com/articles/s41...
@focalplane.bsky.social @nature.com 🧪🔬
What if instead of analyzing 4-6 pathology markers you could check >100 in the *same* sample?
@maltekuehl.com & co @puellesv.bsky.social lab introduce #PathoPlex, method that could even predict disease
Full www.nature.com/articles/s41...
@focalplane.bsky.social @nature.com 🧪🔬
July 18, 2025 at 1:14 PM
#HotFromThePress !!
What if instead of analyzing 4-6 pathology markers you could check >100 in the *same* sample?
@maltekuehl.com & co @puellesv.bsky.social lab introduce #PathoPlex, method that could even predict disease
Full www.nature.com/articles/s41...
@focalplane.bsky.social @nature.com 🧪🔬
What if instead of analyzing 4-6 pathology markers you could check >100 in the *same* sample?
@maltekuehl.com & co @puellesv.bsky.social lab introduce #PathoPlex, method that could even predict disease
Full www.nature.com/articles/s41...
@focalplane.bsky.social @nature.com 🧪🔬
Reposted by CellComM Lab
Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @mbisg.bsky.social, and the Dept of Physiology at @nusingapore.bsky.social in the fall! More about our work on vascular mechanobiology in health & disease mechano-medicine-lab.com
July 9, 2025 at 5:00 PM
Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @mbisg.bsky.social, and the Dept of Physiology at @nusingapore.bsky.social in the fall! More about our work on vascular mechanobiology in health & disease mechano-medicine-lab.com
Reposted by CellComM Lab
This is why we love #cellmigration
#Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis.
I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock !
#scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬
#Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis.
I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock !
#scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬
July 8, 2025 at 10:18 AM
This is why we love #cellmigration
#Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis.
I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock !
#scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬
#Leukocytes: #Neutrophils (cyan) #Macrophages (orange) chemotaxis.
I couldn't share it before the retirement of @zebrafishrock.bsky.social, but cool #microscopy in #zebrafish continue to rock !
#scicomm #scisky @cellcommlab.bsky.social @focalplane.bsky.social 🧪🔬
Reposted by CellComM Lab
🧵 Neural networks meet cell migration in Valencia!
Hi Bluesky! 👋 I'm Javier, computational biologist @cellcommlab.bsky.social l working at the intersection of AI and cell biology 🖥️🧫
Hi Bluesky! 👋 I'm Javier, computational biologist @cellcommlab.bsky.social l working at the intersection of AI and cell biology 🖥️🧫
July 1, 2025 at 10:11 AM
🧵 Neural networks meet cell migration in Valencia!
Hi Bluesky! 👋 I'm Javier, computational biologist @cellcommlab.bsky.social l working at the intersection of AI and cell biology 🖥️🧫
Hi Bluesky! 👋 I'm Javier, computational biologist @cellcommlab.bsky.social l working at the intersection of AI and cell biology 🖥️🧫
Reposted by CellComM Lab
A very late #FluorescenceFriday.
Reposting one of my favorite timelapses from the past year: EB3-mScarlet3 in a HeLa cell, look at those microtubules grow!
Reposting one of my favorite timelapses from the past year: EB3-mScarlet3 in a HeLa cell, look at those microtubules grow!
June 28, 2025 at 5:27 PM
A very late #FluorescenceFriday.
Reposting one of my favorite timelapses from the past year: EB3-mScarlet3 in a HeLa cell, look at those microtubules grow!
Reposting one of my favorite timelapses from the past year: EB3-mScarlet3 in a HeLa cell, look at those microtubules grow!
Reposted by CellComM Lab
Immune cell profiling reveals diverse niches of immune residents of the enteric nervous system and potential neuroimmune interactions
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
June 29, 2025 at 3:03 AM
Immune cell profiling reveals diverse niches of immune residents of the enteric nervous system and potential neuroimmune interactions
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Reposted by CellComM Lab
Read and enjoy this short article about interesting mathematical shapes (plus.maths.org/content/rand...) to learn about random surfaces and the secrets of the Universe!
♾️ #iTeachMath #Science #Maths
Do not miss @plusmaths.bsky.social
Image by Thomas Budzinski (perso.ens-lyon.fr/thomas.budzi...)
♾️ #iTeachMath #Science #Maths
Do not miss @plusmaths.bsky.social
Image by Thomas Budzinski (perso.ens-lyon.fr/thomas.budzi...)
June 29, 2025 at 1:10 PM
Read and enjoy this short article about interesting mathematical shapes (plus.maths.org/content/rand...) to learn about random surfaces and the secrets of the Universe!
♾️ #iTeachMath #Science #Maths
Do not miss @plusmaths.bsky.social
Image by Thomas Budzinski (perso.ens-lyon.fr/thomas.budzi...)
♾️ #iTeachMath #Science #Maths
Do not miss @plusmaths.bsky.social
Image by Thomas Budzinski (perso.ens-lyon.fr/thomas.budzi...)
Reposted by CellComM Lab
📢Our latest preprint list is now up on FocalPlane.
This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included.
focalplane.biologists.com/2025/06/27/m...
This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included.
focalplane.biologists.com/2025/06/27/m...
Microscopy preprints - applications in biology - FocalPlane
Microscopy preprints - applications in biology - News
focalplane.biologists.com
June 27, 2025 at 1:30 PM
📢Our latest preprint list is now up on FocalPlane.
This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included.
focalplane.biologists.com/2025/06/27/m...
This week’s list focusses on research using microscopy tools to answer questions in biology. As always, please let us know if there are other preprints that you’d like to see included.
focalplane.biologists.com/2025/06/27/m...