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Shailaja Seetharaman

@sseethar.bsky.social

240 followers 400 following 18 posts

Incoming Assistant Prof @MBISg, NUS | Interested in mechanobiology | Postdoc, Gardel Lab @UChicago | Schmidt AI in Science and AHA Postdoc | Previously Marie Curie and FRM PhD, Etienne-Manneville Lab @Institut Pasteur

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Shailaja Seetharaman @sseethar.bsky.social · Jul 9

Excited to be starting my research group as a tenure track Presidential Young Professor at the Mechanobiology Institute @mbisg.bsky.social, and the Dept of Physiology at @nusingapore.bsky.social in the fall! More about our work on vascular mechanobiology in health & disease mechano-medicine-lab.com

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Shailaja Seetharaman @sseethar.bsky.social · Aug 26

Thanks, Nitin! Hope you're doing well!

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Reposted by Shailaja Seetharaman

Kate Miroshnikova @katemiro.bsky.social · Aug 15

Pathologists have used nuclear & tissue shapes to diagnose #cancer for decades, but what is the molecular basis for this? In our latest work, we develop a computational pipeline to figure this out in #colorectalcancer! Check out 🧵& preprint #mechanobiology #stemcells www.biorxiv.org/content/10.1...

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Reposted by Shailaja Seetharaman

Jon Humphries @jdhl18.bsky.social · Jun 18

Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis
pubs.aip.org/aip/apb/arti...

Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis

Mechanical forces are fundamental to the formation of normal biological tissues and the maintenance of physiological health. These forces are transmitted from t

pubs.aip.org

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Reposted by Shailaja Seetharaman

Maria Bernabeu @mariabernabeu.bsky.social · Aug 7

We are happy to show one ourt first exciting papers. We have developed a blood-brain barrier model to study the disruptive effects caused by the malaria parasite, Plasmodium falciparum.

First, congratulations to the fearless @liviapiatti.bsky.social and @alinabatzi.bsky.social

rdcu.be/ezBl7

Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model

Nature Communications - Here the authors show that Plasmodium falciparum egress products disrupt endothelial barrier and activate JAK-STAT and interferon type response in a 3D blood-brain barrier...

rdcu.be

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Reposted by Shailaja Seetharaman

Data Science Institute @dsi-uchicago.bsky.social · Jul 30

Congratulations to Thomas Callister, Peter Lu (@petery.lu), Aditya Nandy, Ludwig Schneider, Shailaja Seetharaman (@sseethar.bsky.social), Colm Talbot, Madeleine Torcasso, and Yihang Wang!

Congratulations to Outgoing Eric and Wendy Schmidt AI in Science Fellows – DSI

datascience.uchicago.edu

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Reposted by Shailaja Seetharaman

Amanda Johnson @amandajohnz.bsky.social · Jul 31

Final presentations for Physiology 2025 were last weekend; the students did an awesome job. @sseethar.bsky.social, @andyletzhang.bsky.social, @squishycell.bsky.social, and I were all very proud 🤩.

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Shailaja Seetharaman @sseethar.bsky.social · Jul 12

Thanks, Elias! Hope to see you around sometime soon!

Shailaja Seetharaman @sseethar.bsky.social · Jul 12

Thanks!

Shailaja Seetharaman @sseethar.bsky.social · Jul 12

Thanks, Pablo! :)

Shailaja Seetharaman @sseethar.bsky.social · Jul 12

Thanks!

Shailaja Seetharaman @sseethar.bsky.social · Jul 10

Thanks! :)

Shailaja Seetharaman @sseethar.bsky.social · Jul 10

Thanks!!!

Shailaja Seetharaman @sseethar.bsky.social · Jul 10

Thanks so much, @dianapinheiro.bsky.social. I hope to interact with you more in the future! 🤩

Shailaja Seetharaman @sseethar.bsky.social · Jul 10

Thanks so much, Manuel! Yesss, and of course actin too. You'll be the first to know (only if you promise to keep watching such movies, haha).

Shailaja Seetharaman @sseethar.bsky.social · Jul 9

Ha, just remember - never start a western blot on a Thursday because it's bound to fail. And come help me, I'll tell @squishycell.bsky.social that I need you!

Shailaja Seetharaman @sseethar.bsky.social · Jul 9

Thanks, looking forward to our future collaboration!

Shailaja Seetharaman @sseethar.bsky.social · Jul 9

Thanks!!

Shailaja Seetharaman @sseethar.bsky.social · Jul 9

Thanks to the @schmidtsciences.bsky.social AI in Science Postdoc Program, @ahascience.bsky.social, @dsi-uchicago.bsky.social, and the Yen Fellowship for supporting my postdoctoral research.

Shailaja Seetharaman @sseethar.bsky.social · Jul 9

In the Vascular Mechano-Medicine Lab, we will unravel the mechanobiology of vascular systems to improve human health, with a focus on decoding and engineering tissue function. Starting this fall, we are hiring at all levels, please contact me if you're interested. More details on: shorturl.at/RXKh6

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Shailaja Seetharaman @sseethar.bsky.social · Jul 9

I'm grateful to my advisors and mentors, @etiennemanneville.bsky.social, @squishycell.bsky.social, @manuelthery.bsky.social, Yun Fang, Anne Ridley, and Sasha Bershadsky, as well as colleagues for their immense support and encouragement throughout this journey.

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Shailaja Seetharaman @sseethar.bsky.social · Jul 9

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Reposted by Shailaja Seetharaman

Institute of Molecular Biotechnology @imbavienna.bsky.social · Apr 28

The first objective of IMBA is to make its scientists successful. Let us help you turn ideas into discovery! IMBA is hiring a Junior Group Leader in the molecular life sciences. Apply below. #hiring #biology #research #groupleader #europe

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Reposted by Shailaja Seetharaman

Benoit Ladoux @bladoux.bsky.social · Apr 10

🌿✨ Calling all mechanobiologists, bioengineers, and curious minds! ✨🌿
Join us in Vietnam this year for an unforgettable Conference on Mechanobiology, where science meets culture in one of Southeast Asia’s most vibrant destinations.
📅 06-12 July
📍 Quy Nhon, Vietnam
🔗 icisequynhon.com/conferences/...

Mechanobiology 2025

icisequynhon.com

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Reposted by Shailaja Seetharaman

Sergio Cruz-León @sergiocruzleon.bsky.social · Apr 11

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social

🔗 Preprint here tinyurl.com/3a74uanv

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Reposted by Shailaja Seetharaman

BPPB Seminar Series @bppbseminar.bsky.social · Apr 9

Join us Friday April 11 for talks by David Hathcock @davidhathcock.bsky.social (Mechanisms for dissipation-enhanced adaptation & cooperative sensing in bacterial chemotaxis) & Shailaja Seetharaman @sseethar.bsky.social (Mechanosensitive LIM domain protein FHL2 tunes endothelial function) #biophysics

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