Pablo J. Sáez
@pjsaez.bsky.social
Husband - Dad of 2 - Scientist 🇨🇱 Chilean expat.
I love to study how cells walk & talk.
PI of the @cellcommlab.bsky.social
#CellMigration #CellComm #calciumsignaling #organelles 🧪🔬
I love to study how cells walk & talk.
PI of the @cellcommlab.bsky.social
#CellMigration #CellComm #calciumsignaling #organelles 🧪🔬
Pinned
Pablo J. Sáez
@pjsaez.bsky.social
· Jan 18
How cells decide where to go? #CellMigration
Last year we published our 1st paper @cellcommlab.bsky.social, showing how actin-based membrane oscillations define a new direction ( #cancer & non-cancer #cells )
Full www.nature.com/articles/s41...
@naturephysics.bsky.social @focalplane.bsky.social 🧪🔬
Last year we published our 1st paper @cellcommlab.bsky.social, showing how actin-based membrane oscillations define a new direction ( #cancer & non-cancer #cells )
Full www.nature.com/articles/s41...
@naturephysics.bsky.social @focalplane.bsky.social 🧪🔬
Reposted by Pablo J. Sáez
Interested in cell-cell communication and microscopy? We are searching for a motivated postdoctoral researcher to join Münster! Please Apply! @uni-muenster.de
January 19, 2026 at 4:54 PM
Interested in cell-cell communication and microscopy? We are searching for a motivated postdoctoral researcher to join Münster! Please Apply! @uni-muenster.de
Reposted by Pablo J. Sáez
Following on from her beautiful featured image post on FocalPlane, Christina Daly @christinaadaly.bsky.social shares her top tips for imaging cytonemes.
@labogden.bsky.social.
focalplane.biologists.com/2026/01/19/c...
@labogden.bsky.social.
focalplane.biologists.com/2026/01/19/c...
Cytoneme Imaging Tips and Tricks - FocalPlane
Cytoneme Imaging Tips and Tricks - How to
focalplane.biologists.com
January 19, 2026 at 1:30 PM
Following on from her beautiful featured image post on FocalPlane, Christina Daly @christinaadaly.bsky.social shares her top tips for imaging cytonemes.
@labogden.bsky.social.
focalplane.biologists.com/2026/01/19/c...
@labogden.bsky.social.
focalplane.biologists.com/2026/01/19/c...
#FluorescenceFriday
Jost, Schweizer et al. @ Cuello lab found that a mutation linked to aortic aneurysmas led to distorted actin #cytoskeleton in VSMCs #mechanobiology
New collab @cellcommlab.bsky.social by @jboixcampos.bsky.social🔥
Full www.sciencedirect.com/science/arti...
#microscopy #cell 🧪🔬
Jost, Schweizer et al. @ Cuello lab found that a mutation linked to aortic aneurysmas led to distorted actin #cytoskeleton in VSMCs #mechanobiology
New collab @cellcommlab.bsky.social by @jboixcampos.bsky.social🔥
Full www.sciencedirect.com/science/arti...
#microscopy #cell 🧪🔬
January 16, 2026 at 9:43 PM
#FluorescenceFriday
Jost, Schweizer et al. @ Cuello lab found that a mutation linked to aortic aneurysmas led to distorted actin #cytoskeleton in VSMCs #mechanobiology
New collab @cellcommlab.bsky.social by @jboixcampos.bsky.social🔥
Full www.sciencedirect.com/science/arti...
#microscopy #cell 🧪🔬
Jost, Schweizer et al. @ Cuello lab found that a mutation linked to aortic aneurysmas led to distorted actin #cytoskeleton in VSMCs #mechanobiology
New collab @cellcommlab.bsky.social by @jboixcampos.bsky.social🔥
Full www.sciencedirect.com/science/arti...
#microscopy #cell 🧪🔬
Reposted by Pablo J. Sáez
Issue 24 is complete
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
January 6, 2026 at 10:49 AM
Issue 24 is complete
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
#FluorescenceFriday
Proud of our the last paper @cellcommlab.bsky.social & 1st one of @jboixcampos.bsky.social
We continue to study #CellMigration & how cells decide where to go: ↖️↗️⬇️?
(movie of the actin #cytoskeleton)
Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬
Proud of our the last paper @cellcommlab.bsky.social & 1st one of @jboixcampos.bsky.social
We continue to study #CellMigration & how cells decide where to go: ↖️↗️⬇️?
(movie of the actin #cytoskeleton)
Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬
January 9, 2026 at 4:23 PM
#FluorescenceFriday
Proud of our the last paper @cellcommlab.bsky.social & 1st one of @jboixcampos.bsky.social
We continue to study #CellMigration & how cells decide where to go: ↖️↗️⬇️?
(movie of the actin #cytoskeleton)
Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬
Proud of our the last paper @cellcommlab.bsky.social & 1st one of @jboixcampos.bsky.social
We continue to study #CellMigration & how cells decide where to go: ↖️↗️⬇️?
(movie of the actin #cytoskeleton)
Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬
Reposted by Pablo J. Sáez
Our work is finally published in @science.org Advances! 🎉
My very first paper, and what a journey it's been 🙂↕️
Huge thanks to the whole team, and especially to @pjsaez.bsky.social for believing in me. It turned out way better than I could've ever dreamt ✨
📄 science.org/doi/10.1126/sciadv.ads2734
My very first paper, and what a journey it's been 🙂↕️
Huge thanks to the whole team, and especially to @pjsaez.bsky.social for believing in me. It turned out way better than I could've ever dreamt ✨
📄 science.org/doi/10.1126/sciadv.ads2734
January 7, 2026 at 1:09 PM
Our work is finally published in @science.org Advances! 🎉
My very first paper, and what a journey it's been 🙂↕️
Huge thanks to the whole team, and especially to @pjsaez.bsky.social for believing in me. It turned out way better than I could've ever dreamt ✨
📄 science.org/doi/10.1126/sciadv.ads2734
My very first paper, and what a journey it's been 🙂↕️
Huge thanks to the whole team, and especially to @pjsaez.bsky.social for believing in me. It turned out way better than I could've ever dreamt ✨
📄 science.org/doi/10.1126/sciadv.ads2734
Reposted by Pablo J. Sáez
👁️I spy our Scientific Advisory Board members on the @jcellsci.bsky.social cover.
FocalPlane is a youngster at 5 years old, but we're looking forward to continuing our development in 2026 with the help of the #microscopy and #cellbio communities.
FocalPlane is a youngster at 5 years old, but we're looking forward to continuing our development in 2026 with the help of the #microscopy and #cellbio communities.
Issue 24 is complete
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
Marking the end of @biologists.bsky.social 100-year anniversary celebrations, our cover features members of the JCS community, including some researchers from our ‘First Person’ & ‘Cell Scientists to Watch’ interviews.
Explore our ToC: journals.biologists.com/jcs/issue/13...
January 7, 2026 at 10:00 AM
👁️I spy our Scientific Advisory Board members on the @jcellsci.bsky.social cover.
FocalPlane is a youngster at 5 years old, but we're looking forward to continuing our development in 2026 with the help of the #microscopy and #cellbio communities.
FocalPlane is a youngster at 5 years old, but we're looking forward to continuing our development in 2026 with the help of the #microscopy and #cellbio communities.
Reposted by Pablo J. Sáez
🔬 🖥️ Applications are open for the CSHL course Quantitative Imaging: From Acquisition to Analysis (April 6–21, 2026)!
An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools.
🗓️ Apply online by Jan 30, 2026
An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools.
🗓️ Apply online by Jan 30, 2026
Quantitative Imaging: From Acquisition to Analysis
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
meetings.cshl.edu
January 6, 2026 at 7:18 PM
🔬 🖥️ Applications are open for the CSHL course Quantitative Imaging: From Acquisition to Analysis (April 6–21, 2026)!
An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools.
🗓️ Apply online by Jan 30, 2026
An intensive, hands-on course covering advanced fluorescence microscopy and quantitative image analysis using open-source tools.
🗓️ Apply online by Jan 30, 2026
#HappyNewYear !
Let's start 2026 with a @cellcommlab.bsky.social paper
How many branches is OK during #CellMigration?
It depends on the #cell: for ex. immune cells are just fine.
In collab. w. #NirGov @hfspo.bsky.social
Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬
Let's start 2026 with a @cellcommlab.bsky.social paper
How many branches is OK during #CellMigration?
It depends on the #cell: for ex. immune cells are just fine.
In collab. w. #NirGov @hfspo.bsky.social
Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬
January 1, 2026 at 8:59 PM
#HappyNewYear !
Let's start 2026 with a @cellcommlab.bsky.social paper
How many branches is OK during #CellMigration?
It depends on the #cell: for ex. immune cells are just fine.
In collab. w. #NirGov @hfspo.bsky.social
Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬
Let's start 2026 with a @cellcommlab.bsky.social paper
How many branches is OK during #CellMigration?
It depends on the #cell: for ex. immune cells are just fine.
In collab. w. #NirGov @hfspo.bsky.social
Full www.science.org/doi/10.1126/...
@focalplane.bsky.social @science.org 🧪🔬
Reposted by Pablo J. Sáez
Our final #preprint list of 2025 is now up on FocalPlane!
In this post, we focus on recent (and recently updated) preprints in bioimage analysis. Let us know if you have any recommendations of preprints that we have missed.
focalplane.biologists.com/2025/12/29/m...
In this post, we focus on recent (and recently updated) preprints in bioimage analysis. Let us know if you have any recommendations of preprints that we have missed.
focalplane.biologists.com/2025/12/29/m...
Microscopy preprints: bioimage analysis - FocalPlane
Microscopy preprints: bioimage analysis - News
focalplane.biologists.com
December 29, 2025 at 5:53 PM
Our final #preprint list of 2025 is now up on FocalPlane!
In this post, we focus on recent (and recently updated) preprints in bioimage analysis. Let us know if you have any recommendations of preprints that we have missed.
focalplane.biologists.com/2025/12/29/m...
In this post, we focus on recent (and recently updated) preprints in bioimage analysis. Let us know if you have any recommendations of preprints that we have missed.
focalplane.biologists.com/2025/12/29/m...
Reposted by Pablo J. Sáez
Just making sure that 2025 is definitely over
January 1, 2026 at 4:43 AM
Just making sure that 2025 is definitely over
Reposted by Pablo J. Sáez
RhoGAP15B RNAi collapses leader protrusions, while RhoGAP15B OE stabilises and extends them, underscoring tight control protrusion dynamics.
December 31, 2025 at 2:32 PM
RhoGAP15B RNAi collapses leader protrusions, while RhoGAP15B OE stabilises and extends them, underscoring tight control protrusion dynamics.
Reposted by Pablo J. Sáez
CiliaBuilder creates 3D structural models of cilia and centrioles within ChimeraX constructing microtubule-based architectures, including doublets, triplets, and various ciliary configurations from theoretical models. youtu.be/OEJJZ-qedoY
December 30, 2025 at 9:38 PM
CiliaBuilder creates 3D structural models of cilia and centrioles within ChimeraX constructing microtubule-based architectures, including doublets, triplets, and various ciliary configurations from theoretical models. youtu.be/OEJJZ-qedoY
Reposted by Pablo J. Sáez
Reposted by Pablo J. Sáez
Last couple of days to vote for your favourite 'Featured image' from 2025 ❤️🔬!
focalplane.biologists.com/2025/12/19/v...
focalplane.biologists.com/2025/12/19/v...
December 29, 2025 at 11:23 AM
Last couple of days to vote for your favourite 'Featured image' from 2025 ❤️🔬!
focalplane.biologists.com/2025/12/19/v...
focalplane.biologists.com/2025/12/19/v...
Reposted by Pablo J. Sáez
🚨New preprint(1/2)! We show that RTK fusion oncoproteins broadly suppress EGFR signaling. How? Sequestration of adapters as the shared principle.
Led by superb PhD student Carol Gao.
www.biorxiv.org/content/10.1...
Implications for drug tolerance/resistance, and includes one big surprise🫧.👇
Led by superb PhD student Carol Gao.
www.biorxiv.org/content/10.1...
Implications for drug tolerance/resistance, and includes one big surprise🫧.👇
December 16, 2025 at 12:05 PM
🚨New preprint(1/2)! We show that RTK fusion oncoproteins broadly suppress EGFR signaling. How? Sequestration of adapters as the shared principle.
Led by superb PhD student Carol Gao.
www.biorxiv.org/content/10.1...
Implications for drug tolerance/resistance, and includes one big surprise🫧.👇
Led by superb PhD student Carol Gao.
www.biorxiv.org/content/10.1...
Implications for drug tolerance/resistance, and includes one big surprise🫧.👇
Reposted by Pablo J. Sáez
‼️🚨Hi all! The next Bioc Soc Membrane Contact Site Meeting will be in Chepstow, UK 28-30th Sept 2026. Fantastic speakers with talk slots still available. Sign up & abstract submission now open - limited spaces so register early! Hope to see you all there. Please share + RT 🙏
December 28, 2025 at 7:28 AM
‼️🚨Hi all! The next Bioc Soc Membrane Contact Site Meeting will be in Chepstow, UK 28-30th Sept 2026. Fantastic speakers with talk slots still available. Sign up & abstract submission now open - limited spaces so register early! Hope to see you all there. Please share + RT 🙏
Reposted by Pablo J. Sáez
CRC cells pulling on Collagen I show increased calcium fluctuations, visualized with the calcium reporter K-GECO1
November 7, 2025 at 4:33 PM
CRC cells pulling on Collagen I show increased calcium fluctuations, visualized with the calcium reporter K-GECO1
Reposted by Pablo J. Sáez
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
November 4, 2025 at 10:40 PM
My new ImageJ / Fiji toolkit is out 🔥! The goal is to make image handling & visualization easy, with an intuitive interface! Install it on Fiji with the "Image Viewer" update site
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
#microscopy #ImageJ #FluorescenceFriday #microscopyMonday
imagej.net/plugins/imag...
Reposted by Pablo J. Sáez
Cell migration is a key cellular process that drives major developmental programs and diseases.
Different assays have been developed, but they are often used interchangeably.
In our new paper, we describe how to select the optimal assay.
More details here: www.nature.com/articles/s41...
Different assays have been developed, but they are often used interchangeably.
In our new paper, we describe how to select the optimal assay.
More details here: www.nature.com/articles/s41...
December 27, 2025 at 12:46 PM
Cell migration is a key cellular process that drives major developmental programs and diseases.
Different assays have been developed, but they are often used interchangeably.
In our new paper, we describe how to select the optimal assay.
More details here: www.nature.com/articles/s41...
Different assays have been developed, but they are often used interchangeably.
In our new paper, we describe how to select the optimal assay.
More details here: www.nature.com/articles/s41...
Reposted by Pablo J. Sáez
Attention scientists from all over the world🙃
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences
December 15, 2025 at 2:52 PM
Attention scientists from all over the world🙃
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences
The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪
Get your international & interdisciplinary team. It's time to put your bold research idea into practice!
🔗https://bit.ly/48VsGCG
📅 15 Dec 2025–26 Mar 2026
#sts #LifeSciences
Reposted by Pablo J. Sáez
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Creation of new junior research groups at the Institut Pasteur - Call for applications 2026 - Research
The Institut Pasteur is launching an international call to recruit new junior research group leaders leveraging cutting-edge transdisciplinary approaches to exploring infectious diseases, host-microbe...
research.pasteur.fr
December 8, 2025 at 8:53 AM
🔬 Call to create junior research groups at the Institut Pasteur
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Focus: Infectious diseases, host-microbe interactions, vaccines
Special interest: AI methodologies
📅 Deadline: Feb 9, 2026
👥 2-12 years post-PhD
Apply now 📝 research.pasteur.fr/en/call/crea...
#JobOpportunity #Research
Reposted by Pablo J. Sáez
Come work with us! We are looking for a postdoc in #philbio or #philphysics to work on an interdisciplinary project that adopts the lens of self-organization & active matter to explore the boundary between living & nonliving systems www.kuleuven.be/personeel/jo... #academicsky #philjobs #HPS #evosky
December 8, 2025 at 11:21 AM
Come work with us! We are looking for a postdoc in #philbio or #philphysics to work on an interdisciplinary project that adopts the lens of self-organization & active matter to explore the boundary between living & nonliving systems www.kuleuven.be/personeel/jo... #academicsky #philjobs #HPS #evosky
Reposted by Pablo J. Sáez
Interested in cell adhesion, evolution of multicellularity, or developing tools for emerging marine models?
My lab at UM is hiring a postdoc, and the application is now open:
🔗 tinyurl.com/28jvu4aa
If you know anyone looking for a postdoc, please pass this along!
My lab at UM is hiring a postdoc, and the application is now open:
🔗 tinyurl.com/28jvu4aa
If you know anyone looking for a postdoc, please pass this along!
December 8, 2025 at 6:37 PM
Interested in cell adhesion, evolution of multicellularity, or developing tools for emerging marine models?
My lab at UM is hiring a postdoc, and the application is now open:
🔗 tinyurl.com/28jvu4aa
If you know anyone looking for a postdoc, please pass this along!
My lab at UM is hiring a postdoc, and the application is now open:
🔗 tinyurl.com/28jvu4aa
If you know anyone looking for a postdoc, please pass this along!
Reposted by Pablo J. Sáez
Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB @ascbiology.bsky.social in Philadelphia. Just drop me a line.
December 4, 2025 at 8:42 AM
Are you interested in cytoskeleton and looking for a postdoc position? I will be advertising positions in the new year but happy to chat in person if you are attending ASCB @ascbiology.bsky.social in Philadelphia. Just drop me a line.