Ricky Wolff
@rwolff.bsky.social
490 followers 430 following 63 posts
Ecology and evolution of the human gut microbiome in Nandita Garud's lab at UCLA
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Reposted by Ricky Wolff
martinadalbello.bsky.social
Check out our new paper led by brilliant @jhuisman.bsky.social about how microbial communities cope with stress due to increasing salinity in their environment. We have all your favorites: isolate phenotyping, pairwise competitions, community propagations, and theory. #microsky #mevosky #ecosky
Reposted by Ricky Wolff
erikvannimwegen.bsky.social
Because of a lack of separation of the time scales for TF binding/unbinding and fluctuations in active TF levels, non-equilibrium gene regulation may be common in bacteria.
Check out this nice piece by ‪@philipcball.bsky.social‬ on our new publication in PRX Life.
physics.aps.org/articles/v18...
Different Bacterial Genes Have Different Turn-Ons
Not all genes respond in the same way to regulation by the same molecule—a property that might enable cells to produce complex genetic responses.
physics.aps.org
Reposted by Ricky Wolff
paczkowskilab.bsky.social
The Wadsworth Center, New York State Department of Health, is currently recruiting for a Research Scientist 5 (Assistant/Associate Professor equivalent) to lead an independent research program focused on zoonotic and/or vector-borne pathogens (viral and bacterial).
Reposted by Ricky Wolff
unibas.ch
Bacteria have a simple yet potent mechanism that controls their sensitivity to environmental stimuli. A new study by researchers led by <a href="https://bsky.app/profile/did:plc:mpi2uwwkiofxvcgr5lzmjnra" class="hover:underline text-blue-600 dark:text-sky-400" target="_blank" rel="noopener">@erikvannimwegen.bsky.social @biozentrum.unibas.ch shows: the slower cells grow, the more sensitively they respond to their environment.
Slow-growing bacteria respond more sensitively to their environment
Bacteria have a simple yet potent mechanism that controls their sensitivity to environmental stimuli. A new study by researchers at the Univer...
www.unibas.ch
rwolff.bsky.social
To me, it's telling that even strains that have evolved separately for a long time coexist readily (see FMT study below). I feel this strongly implicates physiological/metabolic flexibility, rather than fixed niche differentiation, as a driver of coexistence

www.science.org/doi/10.1126/...
Durable coexistence of donor and recipient strains after fecal microbiota transplantation
The mystery of the success of clinical microbial transplant therapy is beginning to be decoded.
www.science.org
rwolff.bsky.social
What does the fact that we see closely related bacterial strains stably coexisting in the human gut microbiome, in cheese cultures, in solar salterns, in the LTEE—really wherever we look—tell us about microbial physiology, ecology, and evolution?
rwolff.bsky.social
so much creativity!
rwolff.bsky.social
following up in a different study system,
rwolff.bsky.social
Whimsical Friday afternoon read—1976 study of the microbiomes of astronauts undergoing isolation training, which concluded B. theta abundance responds specifically to "anger stress"
Reposted by Ricky Wolff
phylogenomics.bsky.social
Wow

www.biorxiv.org/content/10.1...

A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome
rwolff.bsky.social
... but how many genetic edits would one have to make to actually get a new species?
Reposted by Ricky Wolff
microjacob.bsky.social
Taxa is hiring! We're looking for a Computational Biologist to spearhead the analysis of massive genomic datasets for our flagship probiotics. Exciting science, great team, and transparent compensation. Apply here 👇
Taxa hiring Computational Biologist in San Francisco, CA | LinkedIn
Posted 4:13:15 PM. The OpportunityWe are looking for a talented Computational Biologist to spearhead the analysis of…See this and similar jobs on LinkedIn.
www.linkedin.com
Reposted by Ricky Wolff
bkoskella.bsky.social
Know any soon to graduate or recently graduated undergrads interested in a full year, paid postbac research position in microbiome sciences? Have them join our zoom Q&A session on Friday, April 11, 11:30am-12:30pm PST. More info here: sites.google.com/berkeley.edu...
Bay Area RaMP - 2025-26 Cohort
2025-2026 Cohort
sites.google.com
rwolff.bsky.social
I love that "adaptation" here is explored across scales—from physiology/gene regulation, to ecology, to evolution over short (within host) and long (across many host lifetimes) timescales