Féaron Cassidy, PhD
@fearoncassidy.bsky.social
💼DOROTHY EU COFUND fellow
🔵Physoc Trustee
👂🏼Pronounced “Fair-on”
🌏Karolinksa Institute, Sweden
previously Maynooth Uni IRL, Uni of Galway IRL, QMUL London UK, Uni of Nottingham UK, TCD Dublin IRL
🥼obesity-assoc cancer immunology
❤️wild swimming
⚧️She/her
🔵Physoc Trustee
👂🏼Pronounced “Fair-on”
🌏Karolinksa Institute, Sweden
previously Maynooth Uni IRL, Uni of Galway IRL, QMUL London UK, Uni of Nottingham UK, TCD Dublin IRL
🥼obesity-assoc cancer immunology
❤️wild swimming
⚧️She/her
Reposted by Féaron Cassidy, PhD
The US Department of Agriculture has ordered that "states must immediately undo any steps taken to issue full SNAP benefits for November 2025".
November 9, 2025 at 5:50 PM
The US Department of Agriculture has ordered that "states must immediately undo any steps taken to issue full SNAP benefits for November 2025".
Reposted by Féaron Cassidy, PhD
Can better understanding misogyny stop gun violence? @bradgage.bsky.social talks to extremism expert and Man Up author @milleridriss.bsky.social for the Real Feels podcast:
Can Understanding Misogyny Stop Gun Violence? - With Cynthia Miller Idriss
Podcast Episode · Real Feels - Modern Masculinity with Brad Gage · 10/28/2025 · 36m
apple.co
October 31, 2025 at 7:52 PM
Can better understanding misogyny stop gun violence? @bradgage.bsky.social talks to extremism expert and Man Up author @milleridriss.bsky.social for the Real Feels podcast:
Reposted by Féaron Cassidy, PhD
Online now: TCR signaling via NFATc1 constrains IL-15-induced bystander activation of human memory CD8+ T cells
TCR signaling via NFATc1 constrains IL-15-induced bystander activation of human memory CD8+ T cells
Memory CD8+ T cells can undergo TCR-dependent or -independent activation. Here, Lee et al. show that IL-15-induced bystander activation of human memory CD8+ T cells is suppressed by concurrent TCR signaling through NFATc1-AP-1 interactions. Furthermore, they validate a bystander activation gene set induced by IL-15 and decreased upon TCR stimulation.
dlvr.it
October 31, 2025 at 7:55 PM
Online now: TCR signaling via NFATc1 constrains IL-15-induced bystander activation of human memory CD8+ T cells
Reposted by Féaron Cassidy, PhD
Reposted by Féaron Cassidy, PhD
excited to read this preprint from rabinowitz lab- how does the body decide which nutrients are burned, and how can this go wrong in T2 diabetes?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Competitive catabolism in systemic metabolic homeostasis
Systemic metabolic homeostasis maintains circulating nutrient concentrations within physiological ranges. Insulin is central to this process, lowering circulating levels of glucose, free fatty acids, ...
www.biorxiv.org
October 31, 2025 at 7:40 PM
excited to read this preprint from rabinowitz lab- how does the body decide which nutrients are burned, and how can this go wrong in T2 diabetes?
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Féaron Cassidy, PhD
Every time someone says “We DoNt kNoW hOw To Do GoOd ScICoMm!” a meteorologist loses their wings**.
**shit
**shit
October 21, 2025 at 12:36 PM
Every time someone says “We DoNt kNoW hOw To Do GoOd ScICoMm!” a meteorologist loses their wings**.
**shit
**shit
Reposted by Féaron Cassidy, PhD
"43% drop in peanut allergies"
Good example of how science evolves.
And "how a public health recommendation can change children’s health.”
And how good research (support, pls) informs policy.
Peanut Allergies Have Plummeted in Children, Study Shows www.nytimes.com/2025/10/20/w...
Good example of how science evolves.
And "how a public health recommendation can change children’s health.”
And how good research (support, pls) informs policy.
Peanut Allergies Have Plummeted in Children, Study Shows www.nytimes.com/2025/10/20/w...
Peanut Allergies Have Plummeted in Children, Study Shows
www.nytimes.com
October 20, 2025 at 8:07 PM
"43% drop in peanut allergies"
Good example of how science evolves.
And "how a public health recommendation can change children’s health.”
And how good research (support, pls) informs policy.
Peanut Allergies Have Plummeted in Children, Study Shows www.nytimes.com/2025/10/20/w...
Good example of how science evolves.
And "how a public health recommendation can change children’s health.”
And how good research (support, pls) informs policy.
Peanut Allergies Have Plummeted in Children, Study Shows www.nytimes.com/2025/10/20/w...
Reposted by Féaron Cassidy, PhD
Oh here’s another hill I like to die on.
No outdoor cats. If you have outdoor cats you’re a self absorbed asshole and should not be allowed to have pets.
No outdoor cats. If you have outdoor cats you’re a self absorbed asshole and should not be allowed to have pets.
Do you have any extremely niche, but serious, ethical stances?
October 20, 2025 at 3:27 AM
Oh here’s another hill I like to die on.
No outdoor cats. If you have outdoor cats you’re a self absorbed asshole and should not be allowed to have pets.
No outdoor cats. If you have outdoor cats you’re a self absorbed asshole and should not be allowed to have pets.
Reposted by Féaron Cassidy, PhD
Meanwhile in the UK
"Do you think it was wrong to leave the EU?"
"Yes."
"And yet you would vote for the people who told you leaving the EU is a good idea?"
"Sure, why not?"
"Do you think it was wrong to leave the EU?"
"Yes."
"And yet you would vote for the people who told you leaving the EU is a good idea?"
"Sure, why not?"
October 20, 2025 at 10:22 AM
Meanwhile in the UK
"Do you think it was wrong to leave the EU?"
"Yes."
"And yet you would vote for the people who told you leaving the EU is a good idea?"
"Sure, why not?"
"Do you think it was wrong to leave the EU?"
"Yes."
"And yet you would vote for the people who told you leaving the EU is a good idea?"
"Sure, why not?"
Reposted by Féaron Cassidy, PhD
Our newest publication is out, and it is most certainly a colorful one!!
Using carefully controlled experiments in keratinocytes, we show that different light wavelengths affect cell metabolism and integrity in different manners.
febs.onlinelibrary.wiley.com/doi/10.1002/...
Using carefully controlled experiments in keratinocytes, we show that different light wavelengths affect cell metabolism and integrity in different manners.
febs.onlinelibrary.wiley.com/doi/10.1002/...
October 20, 2025 at 9:39 AM
Our newest publication is out, and it is most certainly a colorful one!!
Using carefully controlled experiments in keratinocytes, we show that different light wavelengths affect cell metabolism and integrity in different manners.
febs.onlinelibrary.wiley.com/doi/10.1002/...
Using carefully controlled experiments in keratinocytes, we show that different light wavelengths affect cell metabolism and integrity in different manners.
febs.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Féaron Cassidy, PhD
For day 12 of #spacetober_challenge prompt eclipse: #mathematician & #astronomer Nicole-Reine Lepaute (1723-1788) and her calculated path of the solar eclipse of 1764. 🧪🐡👩🏼🔬🧮🔭 #histsci She also worked with Alexis Clairaut & Jérôme Lalande to precisely calculate the date of return of Halley’s Comet, 🧵
October 12, 2025 at 12:25 PM
For day 12 of #spacetober_challenge prompt eclipse: #mathematician & #astronomer Nicole-Reine Lepaute (1723-1788) and her calculated path of the solar eclipse of 1764. 🧪🐡👩🏼🔬🧮🔭 #histsci She also worked with Alexis Clairaut & Jérôme Lalande to precisely calculate the date of return of Halley’s Comet, 🧵
Reposted by Féaron Cassidy, PhD
Awesome public health news:
Maldives becomes the first country to achieve ‘triple elimination’ of
1. mother-to-child transmission of HIV,
2. Syphilis and
3. Hepatitis B
www.who.int/news/item/13...
Maldives becomes the first country to achieve ‘triple elimination’ of
1. mother-to-child transmission of HIV,
2. Syphilis and
3. Hepatitis B
www.who.int/news/item/13...
Maldives becomes the first country to achieve ‘triple elimination’ of mother-to-child transmission of HIV, syphilis and hepatitis B
In a landmark public health achievement, WHO has validated the Maldives for eliminating mother-to-child transmission (EMTCT) of hepatitis B, while maintaining its earlier validation (in 2019) for EMTCT of HIV and syphilis. This makes the Maldives the first country in the world to achieve ‘triple elimination’.
www.who.int
October 14, 2025 at 11:43 AM
Awesome public health news:
Maldives becomes the first country to achieve ‘triple elimination’ of
1. mother-to-child transmission of HIV,
2. Syphilis and
3. Hepatitis B
www.who.int/news/item/13...
Maldives becomes the first country to achieve ‘triple elimination’ of
1. mother-to-child transmission of HIV,
2. Syphilis and
3. Hepatitis B
www.who.int/news/item/13...
Reposted by Féaron Cassidy, PhD
Remarkable recovery of the Klamath River salmon. Many thanks to the agencies, Tribes, and NGOs who came together to remove dams and monitor the recovery of the Klamath River salmon. And kudos, too, to the indigenous youth who paddled source to sea on the newly freed river
October 14, 2025 at 4:49 AM
Remarkable recovery of the Klamath River salmon. Many thanks to the agencies, Tribes, and NGOs who came together to remove dams and monitor the recovery of the Klamath River salmon. And kudos, too, to the indigenous youth who paddled source to sea on the newly freed river
Reposted by Féaron Cassidy, PhD
I am open to the idea that there are people who don't have and don't want to gain the skills to engage directly with their data but every single day that I do I learn the answer to a question you'd never even think to ask unless you were personally staring into the abyss of an uncleaned dataset.
October 10, 2025 at 6:35 PM
I am open to the idea that there are people who don't have and don't want to gain the skills to engage directly with their data but every single day that I do I learn the answer to a question you'd never even think to ask unless you were personally staring into the abyss of an uncleaned dataset.
Reposted by Féaron Cassidy, PhD
Genuinely thrilled to share our new story with the world - an amazing collaboration with @profsharona.bsky.social and Bill Zagotta using their innovative FRET technique to study mitofusin conformational changes. Huge credit to Sophie Hurwitz for tackling this project. urldefense.com/v3/__https:/...
Structural insights into GTP-coupled conformational changes in Mfn1 revealed by time-resolved transition metal ion FRET.
Outer mitochondrial membrane fusion is mediated by the mitofusin paralogs Mfn1 and Mfn2. Nucleotide-driven self-assembly and conformational changes are required for regulated membrane fusion activity,...
urldefense.com
October 10, 2025 at 6:31 PM
Genuinely thrilled to share our new story with the world - an amazing collaboration with @profsharona.bsky.social and Bill Zagotta using their innovative FRET technique to study mitofusin conformational changes. Huge credit to Sophie Hurwitz for tackling this project. urldefense.com/v3/__https:/...
Reposted by Féaron Cassidy, PhD
Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Tertiary lymphoid structures support the development of allergen-specific progenitor CD4+ T cells
Tissue-resident memory CD4+ T cells (TRM) are key sentinels of the adaptive immune response that provide a rapid, robust inflammatory response upon reactivation in non-lymphoid tissues. While CD4+ TRM...
www.biorxiv.org
October 10, 2025 at 7:22 PM
Asthma is a chronic disease characterized by acute, intermittent, recurrent episodes of airway inflammation. A decade of work developing the tools, techniques and collaborations needed to figure out how CD4+ T cells in the lungs propagate disease can be found here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Féaron Cassidy, PhD
The Venezuelan opposition leader was forced to go into hiding in 2024 after being banned form standing in that year’s election.
Nobel peace prize winner Maria Corina Machado: Venezuelan opposition leader forced into hiding after taking on Maduro
The Venezuelan opposition leader was forced to go into hiding in 2024 after being banned form standing in that year’s election.
tcnv.link
October 10, 2025 at 7:28 PM
The Venezuelan opposition leader was forced to go into hiding in 2024 after being banned form standing in that year’s election.
Reposted by Féaron Cassidy, PhD
Immigrant scientists make a massive contribution wherever they go
More than 30% of this century’s science Nobel prizewinners immigrated
www.nature.com/articles/d41...
More than 30% of this century’s science Nobel prizewinners immigrated
www.nature.com/articles/d41...
More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys
The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.
www.nature.com
October 10, 2025 at 6:46 PM
Immigrant scientists make a massive contribution wherever they go
More than 30% of this century’s science Nobel prizewinners immigrated
www.nature.com/articles/d41...
More than 30% of this century’s science Nobel prizewinners immigrated
www.nature.com/articles/d41...
Reposted by Féaron Cassidy, PhD
"We're doing the studies to make the proof."
This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.
This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.
RFK Jr on Tylenol and autism: "It is not proof. We're doing the studies to make the proof."
October 9, 2025 at 6:41 PM
"We're doing the studies to make the proof."
This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.
This is not how Gold Standard Science works. Or any science. You do the study to TEST THE HYPOTHESIS, not to prove yourself right.
Reposted by Féaron Cassidy, PhD
Implantation is inherently a mechanical process. We find contractility is necessary and sufficient for spreading behaviors. We can artificially age embryos from young females and even rescue aged embryo spreading just by tuning contractility!
October 1, 2025 at 6:21 PM
Implantation is inherently a mechanical process. We find contractility is necessary and sufficient for spreading behaviors. We can artificially age embryos from young females and even rescue aged embryo spreading just by tuning contractility!
Reposted by Féaron Cassidy, PhD
THIS IS THE WAY.
Everyone gets their knickers in a twist when I say we can’t sci-comm our way out of this mess…but maybe you’ll listen to the more eloquent and measured @edyong209.bsky.social!
This isn’t happening because people don’t appreciate the brilliance of the double helix structure.
Everyone gets their knickers in a twist when I say we can’t sci-comm our way out of this mess…but maybe you’ll listen to the more eloquent and measured @edyong209.bsky.social!
This isn’t happening because people don’t appreciate the brilliance of the double helix structure.
This moment from our latest episode with science writer @edyong209.bsky.social is 🔥
We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪
Listen wherever, or watch on Spotify 👇
open.spotify.com/episode/7Evh...
We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪
Listen wherever, or watch on Spotify 👇
open.spotify.com/episode/7Evh...
October 1, 2025 at 10:51 PM
THIS IS THE WAY.
Everyone gets their knickers in a twist when I say we can’t sci-comm our way out of this mess…but maybe you’ll listen to the more eloquent and measured @edyong209.bsky.social!
This isn’t happening because people don’t appreciate the brilliance of the double helix structure.
Everyone gets their knickers in a twist when I say we can’t sci-comm our way out of this mess…but maybe you’ll listen to the more eloquent and measured @edyong209.bsky.social!
This isn’t happening because people don’t appreciate the brilliance of the double helix structure.
Reposted by Féaron Cassidy, PhD
The remarkable number of people, me included, who were inspired by her work, life and example is the biggest tribute. Find a way to honor her memory. The wolrd is a bit smaller and sadder with her gone
Jane Goodall, world-renowned primatologist, dies aged 91
Jane Goodall, world-renowned primatologist, dies aged 91
Jane Goodall Institute says ‘tireless advocate’ for natural world died in California during US speaking tour
The world-renowned primatologist Jane Goodall has died at the age of 91, her institute has said.
The Jane Goodall Institute announced that she had passed away of natural causes while in California as part of a US speaking tour. Continue reading...
www.theguardian.com
October 1, 2025 at 11:13 PM
The remarkable number of people, me included, who were inspired by her work, life and example is the biggest tribute. Find a way to honor her memory. The wolrd is a bit smaller and sadder with her gone
Reposted by Féaron Cassidy, PhD
The language of non-consent around AI is really telling. "It's too late to be scared." "It's here whether we want it or not." "You'll have to learn to work with it." "You can't fight the inevitable."
All just variations of "you're not allowed to say no." Creepy technology made by creepy people.
All just variations of "you're not allowed to say no." Creepy technology made by creepy people.
‘It’s too late to be scared’: readers on the controversial rise of AI ‘actors’
‘It’s too late to be scared’: readers on the controversial rise of AI ‘actors’
The birth of AI ‘actor’ Tilly Norwood has caused a backlash in Hollywood and has sparked conversation from Guardian readers
www.theguardian.com
October 1, 2025 at 3:37 PM
The language of non-consent around AI is really telling. "It's too late to be scared." "It's here whether we want it or not." "You'll have to learn to work with it." "You can't fight the inevitable."
All just variations of "you're not allowed to say no." Creepy technology made by creepy people.
All just variations of "you're not allowed to say no." Creepy technology made by creepy people.
Reposted by Féaron Cassidy, PhD
"In 2012, 60 trans-related articles were published by Britain’s media. By 2022, it was more than 7,500, according to figures from Trans Media Watch. The media is not responding to public rage against vulnerable minorities; it is helping to create it." www.prospectmagazine.co.uk/politics/709...
What is a reactionary centrist, and does the UK have them?
A term favoured by US progressives can help us understand Britain’s drift to the right
www.prospectmagazine.co.uk
October 1, 2025 at 1:52 PM
"In 2012, 60 trans-related articles were published by Britain’s media. By 2022, it was more than 7,500, according to figures from Trans Media Watch. The media is not responding to public rage against vulnerable minorities; it is helping to create it." www.prospectmagazine.co.uk/politics/709...
Reposted by Féaron Cassidy, PhD
Check out this new thermo-hot paper from the @colllab.bsky.social Lab. Glad to contribute and work with her team.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
NLRP3 is a thermosensor that is negatively regulated by high temperature
Inflammation is an essential response to infection and injury, but unregulated inflammation is damaging and must be limited by negative feedback signalling. Inflammasome signalling drives local inflam...
www.biorxiv.org
October 1, 2025 at 6:56 AM
Check out this new thermo-hot paper from the @colllab.bsky.social Lab. Glad to contribute and work with her team.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...