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Reposted by Tony Southall

Emma Rawlins @labrawlins.bsky.social · 1d

Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...

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Reposted by Tony Southall

Otto English @ottoenglish.bsky.social · Aug 30

This is where the empty headed Flag shagging leads.

Race hate.

I feel truly heartbroken today. My Chinese takeaway,
which has been serving this community for more than
10 years, was vandalized with hateful graffiti telling us
to "go home."
This is not just paint on the wall - it is blatant
discrimination, and it hurts deeply
The police are already following up on this incident. If
anyone has seen anything or knows who did this,
please contact us
We work hard every day to serve our customers with
love and dedication. I believe our community is
stronger than hate, and 1 hope everyone will stand
together against this kind of behaviour.

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François Leulier @francoisleulier.bsky.social · Jun 28

A Drosophila single-cell 3D spatiotemporal multi-omics atlas unveils panoramic key regulators of cell-type differentiation: Cell
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www.cell.com/cell/abstrac...

A Drosophila single-cell 3D spatiotemporal multi-omics atlas unveils panoramic key regulators of cell-type differentiation

This work introduces Flysta3D-v2, a 3D spatiotemporal multi-omics database that spans Drosophila development from embryogenesis to metamorphosis. Through the integration of multimodal data, we detail ...

www.cell.com

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Reposted by Tony Southall

Yasin Dagdas @plantophagy.bsky.social · Jun 25

How 🆒 is this?!? www.cell.com/cell/abstrac...

A host organelle integrates stolen chloroplasts for animal photosynthesis

Sea slugs steal foreign chloroplasts and store them in specialized organelles that facilitate photosynthesis and eventual digestion to mediate starvation resistance.

www.cell.com

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Reposted by Tony Southall

Cahir O'Kane @cahirokane.bsky.social · Jun 20

That's not what we should be hearing. There is virtually no low-quality research that gets discussed at funding panels, or gets anywhere near being funded. The problem is that not enough high-quality research is funded.

Robin Bisson @robinbisson.bsky.social · Jun 19

Two senior @ukri.org figures this week have suggested unis could reduce how much research they do

“Concentrating on unique and high contributions & concentrating on less research, has the potential to bring the amount of activity into balance with research funding,” Steven Hill told #ARMA25

(1/2)

Research England official: universities could do ‘less’ R&D - Research Professional News

Arma 2025: Director of research asks whether system should provide “disincentives for lower-quality research”

www.researchprofessionalnews.com

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Reposted by Tony Southall

Helena Klara Jambor @helenajambor.bsky.social · Jun 18

I gave in! After students asking for it, I now made a simple figure design checklist.
To help all scientists w/o graphic skills create clear, accessible, and truthful charts!
-> Out in @nature Cell Biology: rdcu.be/erwl4

#DataVisualization #PhD #SciComm

Thx for review @bethcimini.bsky.social + 2

A checklist for designing and improving the visualization of scientific data

Nature Cell Biology - Creating clear and engaging scientific figures is crucial to communicate complex data. In this Comment, I condense principles from design, visual perception and data...

rdcu.be

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Reposted by Tony Southall

Surfin' NuRD @surfinnurd.bsky.social · Jun 11

Postdoc post in my lab from Autumn this year @lsiexeter.bsky.social @exeter.ac.uk
#Chromatin #StemCells #Enhancer #NeuralCrest #Transcription #CellFate
#NuRDIsTheWord
Apply and/or get in touch!

LSI-Exeter @lsiexeter.bsky.social · Jun 9

Looking for a Postdoc? A PDRA position is available in the LSI Exeter with Prof Brian Hendrich from September 2025. Do you have experience in mammalian stem cell culture and a solid understanding of molecular & biochemical lab techniques? Apply! Job Ref: Q05546 jobs.exeter.ac.uk/hrpr_webrecr...

Powered by MHR

jobs.exeter.ac.uk

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Reposted by Tony Southall

Gaynor Ann Smith @gaynorasmith.bsky.social · Jun 11

✨️ Come join my lab! ✨️ I have an ARUK funded post doc position available for a talented ECR to work with Drosophila and human iPSC derived neurons.

krb-sjobs.brassring.com/TGnewUI/Sear...

Job Search | Cardiff University

Search for Internet job results.

krb-sjobs.brassring.com

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Reposted by Tony Southall

Marco Trizzino @marcotrizzino.bsky.social · Jun 10

New paper from my group is out. We demonstrate that cranial neural crest (CNCC) induction requires the transcription factor SALL4 to physically recruit the BAF chromatin remodeller at CNCC-induction enhancers as early as at the neuroectodermal stage:
www.biorxiv.org/content/10.1...

Neural crest induction requires SALL4-mediated BAF recruitment to lineage specific enhancers

Neural crest induction begins early during neural plate formation, requiring precise transcriptional control to activate lineage-specific enhancers. Here, we demonstrate that SALL4, a transcription fa...

www.biorxiv.org

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Reposted by Tony Southall

LSI-Exeter @lsiexeter.bsky.social · Jun 9

Looking for a Postdoc? A PDRA position is available in the LSI Exeter with Prof Brian Hendrich from September 2025. Do you have experience in mammalian stem cell culture and a solid understanding of molecular & biochemical lab techniques? Apply! Job Ref: Q05546 jobs.exeter.ac.uk/hrpr_webrecr...

Powered by MHR

jobs.exeter.ac.uk

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Marc Dionne @marcsdionne.bsky.social · Jun 7

No question, we need to keep FlyBase alive in the present to ensure there's a future.

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Tony Southall @tonysouthall.bsky.social · Jun 6

Whoop! Congratulations!

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Reposted by Tony Southall

Katja Röper @katjaroeper.bsky.social · Jun 4

European Fly PIs: please respond to the email we sent out yesterday and help save FlyBase!

FlyBase @flybase.bsky.social · Jun 3

We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.

Mark A. Hanson @hansonmark.bsky.social · Jun 3

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯

Any lab using @flybase.bsky.social please donate using the link in post below.

This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

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Reposted by Tony Southall

Jose Jimenez @jjimenez.bsky.social · May 30

We are recruiting!! Exciting opportunity to join our team as a Postdoctoral Researcher in the Dept. of Life Sciences at Imperial College as part of the amazing Preventing Plastic Pollution Engineering Biology Hub (P3EB). More information and how to apply here: www.imperial.ac.uk/jobs/search-...

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

www.imperial.ac.uk

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Reposted by Tony Southall

Mike Galsworthy @mikegalsworthy.bsky.social · May 29

UK universities are in the top 3 in global reputation. But they are losing money, cutting programmes, and laying off staff.

International students are the safety net—and it’s being pulled away.

Will the government’s immigration plans be good for our universities?

The Immigration White Paper aims to reduce international student numbers. But universities need them. Can the circle be squared?

eastangliabylines.co.uk

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Reposted by Tony Southall

Isaac Witte @isaacwitte.bsky.social · May 15

Excited to introduce evoCAST: a platform for efficient, programmable gene integration in human cells. This work, a close collab between my PhD lab (Liu group) and @sternberglab.bsky.social, has been such a fun journey to help lead. Huge thanks to all contributors!

www.science.org/doi/10.1126/...

Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase

Programmable gene integration in human cells has the potential to enable mutation-agnostic treatments for loss-of-function genetic diseases and facilitate many applications in the life sciences. CRISP...

www.science.org

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Reposted by Tony Southall

Cambridge for Europe @cambsforeurope.bsky.social · May 13

Am I a stranger now?

Many have asked ourselves this in the past 24 hours, not only because of where we are from, but because of what the UK is becoming.

You don't defeat Faragism by validating its anti-immigrant rhetoric.

Solidarity with the UK's migrants!

www.theguardian.com/politics/202...

Starmer accused of echoing far right with ‘island of strangers’ speech

Prime minister’s immigration speech was likened by MPs to rhetoric of Enoch Powell

www.theguardian.com

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Giorgio Gilestro @giorgio.gilest.ro · May 12

This is insane. Labour is making the very same mistake the Tories made but in a more catastrophic way. A left-leaning party adopting an ultra-right fascist agenda: what could go wrong?

Peter Stefanovic @peterstefanovic.bsky.social · May 12

'Every area of the immigration system - work, family and study - will be tightened up', says PM Keir Starmer

- Skill requirements raised to degree level
- English language requirements increased
- Pathway to citizenship increased from five years to 10

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Reposted by Tony Southall

Christophe 🔬 L @christlet.bsky.social · May 5

Finally! (remember the famous 2022 ASCB poster and Twitter discussion) www.biorxiv.org/content/10.1...

Enhanced axonal transport in large vertebrates: KIF5A adaptations in giraffes and pythons

Efficient axonal transport is essential for neuronal function, particularly in species with exceptionally long axons. The Kinesin-1 motor protein KIF5A plays a key role in this process, but whether an...

www.biorxiv.org

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Rita Strack @ritastrack.bsky.social · May 2

Opportunity alert! It's also not in the USA.

Tom Ellis @proftomellis.bsky.social · May 2

My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑‍🎓 Please RT. It's a great place with world-class expertise in all sorts of biomedical & biological engineering topics like synthetic biology. It's also not in the USA. www.imperial.ac.uk/jobs/search-...

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Reposted by Tony Southall

Cédric Maurange @cedricmaurange.bsky.social · Apr 30

New lab paper out! 😀

We describe a new benchtop technique to isolate microRNAs from various cell types in a complex tissue (like the developing CNS). This is a fruitful collab with the Cremer lab from @ibdm.bsky.social journals.plos.org/plosgenetics... 1/n 🧵

In vivo AGO-APP identifies a module of microRNAs cooperatively preserving neural progenitors

Author summary MicroRNAs (miRNAs) are small RNAs that silence messenger RNAs (mRNAs) by binding to partially complementary sequences. They play a crucial role in cell type specification during develop...

journals.plos.org

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Nikolai Windbichler @nikiwind.bsky.social · Apr 28

New paper/gene drive from the lab! Dropped by NComms on Friday evening on World Malaria Day of all times - without a word of warning….

www.nature.com/articles/s41...

A suppression-modification gene drive for malaria control targeting the ultra-conserved RNA gene mir-184 - Nature Communications

Here, the authors describe a highly efficient gene drive targeting the non-coding miR-184 gene. Disruption of the miR-184 gene by the gene drive reduces mosquito lifespan and interferes with survival ...

www.nature.com

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Tony Southall @tonysouthall.bsky.social · Apr 28

Thanks Julia!!

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Tony Southall @tonysouthall.bsky.social · Apr 27

Great work by @drflyguyni.bsky.social and Freya Storer!

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Tony Southall @tonysouthall.bsky.social · Apr 26

New preprint! We have discovered that the splicing factor Sex lethal (Sxl - well known for its role in sex determination) binds to chromatin and regulates tRNA synthesis in neurons by interacting with RNA Pol III! Highlighting Sxl as a novel modulator of neuronal homeostasis. tinyurl.com/s44s2z95

Sex-lethal is recruited to chromatin to promote neuronal tRNA synthesis in males through RNA Polymerase III regulation

The RNA-binding protein Sex-lethal (Sxl) is classically known as a master regulator of sex determination and mRNA splicing in Drosophila melanogaster. However, this role is not conserved across specie...

tinyurl.com

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