Rosa Uribe, PhD
@uribelab.bsky.social
Bioscientist. Associate Professor at Rice University. Neural crest, zebrafish, enteric nervous system, gut-brain axis, neurodevelopment. Editor-in-Chief, Differentiation.
Pinned
Rosa Uribe, PhD
@uribelab.bsky.social
· Sep 5
Whole‐Gut Spatial Genomic Analysis Reveals Molecular Regionalization of the Differentiating Zebrafish Enteric Nervous System
Spatial genomic analysis of the developing enteric nervous system in zebrafish through multiplex whole mount HCR in slide identified genes that have temporal and spatial expression patterns during de...
faseb.onlinelibrary.wiley.com
Check out our new work led by @rodrigomorec.bsky.social published today! We show that sequential, multiplexed HCR in whole-mount larval zebrafish revealed 3D spatial gene expression groups at the cellular and gut-levels in the enteric nervous system!
faseb.onlinelibrary.wiley.com/doi/10.1096/...
faseb.onlinelibrary.wiley.com/doi/10.1096/...
Reposted by Rosa Uribe, PhD
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
November 19, 2025 at 8:23 PM
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
It was a splendid experience getting to visit University of Miami and @zfishlady.bsky.social!
Fundamental biology is going strong there and I was impressed by the wide range of science going on! The trainees are super friendly and I had a blast. Thank you! 🐟🐠🧪 #zebrafish #devbio
Fundamental biology is going strong there and I was impressed by the wide range of science going on! The trainees are super friendly and I had a blast. Thank you! 🐟🐠🧪 #zebrafish #devbio
November 19, 2025 at 1:26 PM
It was a splendid experience getting to visit University of Miami and @zfishlady.bsky.social!
Fundamental biology is going strong there and I was impressed by the wide range of science going on! The trainees are super friendly and I had a blast. Thank you! 🐟🐠🧪 #zebrafish #devbio
Fundamental biology is going strong there and I was impressed by the wide range of science going on! The trainees are super friendly and I had a blast. Thank you! 🐟🐠🧪 #zebrafish #devbio
Reposted by Rosa Uribe, PhD
Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 17, 2025 at 11:22 PM
Folks, it is finally out! Our paper on T2T assemblies of the zebrafish genome is on BioRxiv:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Rosa Uribe, PhD
🔬 The Marine Biological Laboratory (MBL) is hiring a Hibbitt Imaging Scientist.
Advance next-generation microscopy and apply it to cutting-edge research in cell biology and neuroscience.
📍 Woods Hole, MA
🔗 https://f.mtr.cool/modpfbqtew
#Biology #ScienceJobs @mblscience.bsky.social
Advance next-generation microscopy and apply it to cutting-edge research in cell biology and neuroscience.
📍 Woods Hole, MA
🔗 https://f.mtr.cool/modpfbqtew
#Biology #ScienceJobs @mblscience.bsky.social
November 5, 2025 at 12:30 PM
🔬 The Marine Biological Laboratory (MBL) is hiring a Hibbitt Imaging Scientist.
Advance next-generation microscopy and apply it to cutting-edge research in cell biology and neuroscience.
📍 Woods Hole, MA
🔗 https://f.mtr.cool/modpfbqtew
#Biology #ScienceJobs @mblscience.bsky.social
Advance next-generation microscopy and apply it to cutting-edge research in cell biology and neuroscience.
📍 Woods Hole, MA
🔗 https://f.mtr.cool/modpfbqtew
#Biology #ScienceJobs @mblscience.bsky.social
Reposted by Rosa Uribe, PhD
Inject some #zebrafish into your timeline with our updated Starter Packs! 🧪
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Resources: go.bsky.app/JcC5df3
Sr. Scientists & PIs v1: go.bsky.app/2cHYybY
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November 1, 2025 at 8:09 AM
Inject some #zebrafish into your timeline with our updated Starter Packs! 🧪
WomenInScience v1: go.bsky.app/4BegEjv
"" v2: go.bsky.app/VoebYrt
Resources: go.bsky.app/JcC5df3
Sr. Scientists & PIs v1: go.bsky.app/2cHYybY
"" v2: go.bsky.app/4zBuxAF
"" v3: go.bsky.app/JvjuSZg
"" v4: go.bsky.app/2c4WLQK
WomenInScience v1: go.bsky.app/4BegEjv
"" v2: go.bsky.app/VoebYrt
Resources: go.bsky.app/JcC5df3
Sr. Scientists & PIs v1: go.bsky.app/2cHYybY
"" v2: go.bsky.app/4zBuxAF
"" v3: go.bsky.app/JvjuSZg
"" v4: go.bsky.app/2c4WLQK
Reposted by Rosa Uribe, PhD
🤔 #AskZebrafish from Slack: "Does anyone have a favorite protocol for staining myelin in the brain, especially in fish >21 dpf? We would like a dye, not a line. We're looking into CMC or fluoromyelin but are unsure about penetration into the brain." Any feedback or leads would be appreciated!
October 31, 2025 at 3:06 PM
🤔 #AskZebrafish from Slack: "Does anyone have a favorite protocol for staining myelin in the brain, especially in fish >21 dpf? We would like a dye, not a line. We're looking into CMC or fluoromyelin but are unsure about penetration into the brain." Any feedback or leads would be appreciated!
Reposted by Rosa Uribe, PhD
The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery.
#Microscopy #Lightsheet #syGlass
#Microscopy #Lightsheet #syGlass
October 23, 2025 at 3:33 PM
The #mesoSPIM community just celebrated 10 years of open-source light-sheet microscopy in Zürich! For #3DThursday, we're honoring Martina Schaettin & Fabian Voigt’s iconic 3D chick embryo dataset — a luminous benchmark for open science and shared discovery.
#Microscopy #Lightsheet #syGlass
#Microscopy #Lightsheet #syGlass
Reposted by Rosa Uribe, PhD
NEW: The Editors-in-Chief of Differentiation, @rogerslabucd.bsky.social, @uribelab.bsky.social, and Loydie Jerome-Majewska, have curated a special collection of papers, “Osteo biology: from differentiation to regeneration.” Explore the collection: https://bit.ly/3JlXEey
October 22, 2025 at 5:15 PM
NEW: The Editors-in-Chief of Differentiation, @rogerslabucd.bsky.social, @uribelab.bsky.social, and Loydie Jerome-Majewska, have curated a special collection of papers, “Osteo biology: from differentiation to regeneration.” Explore the collection: https://bit.ly/3JlXEey
Y'all. We got some great applicants we are considering! The future of neuroscience is so exciting! Can't wait to see what these inspirational researchers achieve over the next few years!
The Department of BioSciences at Rice U invites applications for an open rank tenure-track position to begin July 1, 2026. We seek candidates with research programs in theoretical and computational neuroscience, including candidates 1/2
apply.interfolio.com/172558
apply.interfolio.com/172558
Apply - Interfolio
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apply.interfolio.com
October 21, 2025 at 8:53 PM
Y'all. We got some great applicants we are considering! The future of neuroscience is so exciting! Can't wait to see what these inspirational researchers achieve over the next few years!
I have always used them in my writing, going back to grad school days. Wish more people used them TBH...
All these people avoiding m-dashes because “AI uses them” simply means that there’s more for me!
October 21, 2025 at 7:14 PM
I have always used them in my writing, going back to grad school days. Wish more people used them TBH...
Reposted by Rosa Uribe, PhD
It was fun writing this essay, about bottom-up neuroscience and how we might simulate entire brains, using data collected via new technologies (expansion microscopy, optogenetics, whole brain voltage imaging, and more), with @kordinglab.bsky.social!
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology, and how neurons generate behavior, write @kordinglab.bsky.social and @eboyden3.bsky.social.
#neuroskyence
bit.ly/48EzEO8
#neuroskyence
bit.ly/48EzEO8
Whole-brain, bottom-up neuroscience: The time for it is now
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate…
bit.ly
October 21, 2025 at 12:38 AM
It was fun writing this essay, about bottom-up neuroscience and how we might simulate entire brains, using data collected via new technologies (expansion microscopy, optogenetics, whole brain voltage imaging, and more), with @kordinglab.bsky.social!
The future of science is so bright! It was truly an honor to listen to what cool research these amazing undergraduates from around the U.S. have been conducting at the Gulf Coast Undergraduate Research Symposium (GCURS), hosted by Rice University!
Congratulations presenters! 🧪🧬
Congratulations presenters! 🧪🧬
October 20, 2025 at 2:33 PM
The future of science is so bright! It was truly an honor to listen to what cool research these amazing undergraduates from around the U.S. have been conducting at the Gulf Coast Undergraduate Research Symposium (GCURS), hosted by Rice University!
Congratulations presenters! 🧪🧬
Congratulations presenters! 🧪🧬
Reposted by Rosa Uribe, PhD
Just here to remind everyone that while the federal government is shutdown, all study sections at the NIH are currently on hold. Another blow to science and to early career scientists like myself with young labs and research groups. Very hard to remain positive about this career path.
October 14, 2025 at 3:34 PM
Just here to remind everyone that while the federal government is shutdown, all study sections at the NIH are currently on hold. Another blow to science and to early career scientists like myself with young labs and research groups. Very hard to remain positive about this career path.
Reposted by Rosa Uribe, PhD
Speaking science in a fractured world: making truth land when facts alone cannot
A Perspective by @rebeccacalisi.bsky.social, @kaliceaphd.bsky.social, Jamy Peng, @spiraldoc.bsky.social & @rogerslabucd.bsky.social on how to combat scientific misinformation
journals.biologists.com/dev/article/...
A Perspective by @rebeccacalisi.bsky.social, @kaliceaphd.bsky.social, Jamy Peng, @spiraldoc.bsky.social & @rogerslabucd.bsky.social on how to combat scientific misinformation
journals.biologists.com/dev/article/...
October 13, 2025 at 11:53 AM
Speaking science in a fractured world: making truth land when facts alone cannot
A Perspective by @rebeccacalisi.bsky.social, @kaliceaphd.bsky.social, Jamy Peng, @spiraldoc.bsky.social & @rogerslabucd.bsky.social on how to combat scientific misinformation
journals.biologists.com/dev/article/...
A Perspective by @rebeccacalisi.bsky.social, @kaliceaphd.bsky.social, Jamy Peng, @spiraldoc.bsky.social & @rogerslabucd.bsky.social on how to combat scientific misinformation
journals.biologists.com/dev/article/...
Reposted by Rosa Uribe, PhD
A Cornell University researcher has been developing an artificial heart for children for more than 20 years. Now, his research is on hold and his lab is shut down.
This 4-year-old's heart is failing. A federal grant that might help him was canceled
A Cornell University researcher has been developing an artificial heart for children for more than 20 years. Now, his research is on hold and his lab is shut down.
n.pr
October 12, 2025 at 9:59 PM
A Cornell University researcher has been developing an artificial heart for children for more than 20 years. Now, his research is on hold and his lab is shut down.
Reposted by Rosa Uribe, PhD
New preprint alert! We DNA barcoded 95 thousand Ghanaian arthropods, more than doubling the number of BINs (a species proxy) available online from West Africa. In doing so we’ve released a huge amount of new data to scientists studying the region 🧪 www.biorxiv.org/content/10.1...
Characterising a species-rich and understudied tropical insect fauna using DNA barcoding
Background: West Africa has high biodiversity that is relatively understudied, especially for insects. Studies of West African arthropod diversity can therefore help address important questions regard...
www.biorxiv.org
October 2, 2025 at 7:47 AM
New preprint alert! We DNA barcoded 95 thousand Ghanaian arthropods, more than doubling the number of BINs (a species proxy) available online from West Africa. In doing so we’ve released a huge amount of new data to scientists studying the region 🧪 www.biorxiv.org/content/10.1...
Have been fortunate to host Dr. Margot Williams from @bcmhouston.bsky.social for a seminar today in the Biosciences department at Rice University. Such cool, innovative work! Also, a masterclass in how to deliver a talk.
Thank you for sharing your science, Margot!
Thank you for sharing your science, Margot!
September 22, 2025 at 8:42 PM
Have been fortunate to host Dr. Margot Williams from @bcmhouston.bsky.social for a seminar today in the Biosciences department at Rice University. Such cool, innovative work! Also, a masterclass in how to deliver a talk.
Thank you for sharing your science, Margot!
Thank you for sharing your science, Margot!
Reposted by Rosa Uribe, PhD
New @maxplanck.de study: We looked for left-right differences of gene expression and cell-type abundances in the brains of MICE 🐭using Xenium @10xgenomics.bsky.social. Possible clues to how functional brain asymmetry is supported !! www.biorxiv.org/content/10.1... Short thread below ⬇️
September 12, 2025 at 7:10 AM
New @maxplanck.de study: We looked for left-right differences of gene expression and cell-type abundances in the brains of MICE 🐭using Xenium @10xgenomics.bsky.social. Possible clues to how functional brain asymmetry is supported !! www.biorxiv.org/content/10.1... Short thread below ⬇️
Reposted by Rosa Uribe, PhD
Another tour-de-force from David Baker's lab : custom DNA-binding miniproteins to target specific DNA sequences for diverse applications in gene regulation and editing.
With David, nothing is impossible !
With David, nothing is impossible !
New online: Computational design of sequence-specific DNA-binding proteins
Computational design of sequence-specific DNA-binding proteins
Nature Structural & Molecular Biology, Published online: 12 September 2025; doi:10.1038/s41594-025-01669-4The authors develop a computational method to design small DNA-binding proteins (DBPs) that target specific sequences. Designed DBPs show structural accuracy and function in both bacterial and mammalian cells for transcriptional regulation.
go.nature.com
September 12, 2025 at 10:41 AM
Another tour-de-force from David Baker's lab : custom DNA-binding miniproteins to target specific DNA sequences for diverse applications in gene regulation and editing.
With David, nothing is impossible !
With David, nothing is impossible !
Reposted by Rosa Uribe, PhD
Check out our new work led by @rodrigomorec.bsky.social published today! We show that sequential, multiplexed HCR in whole-mount larval zebrafish revealed 3D spatial gene expression groups at the cellular and gut-levels in the enteric nervous system!
faseb.onlinelibrary.wiley.com/doi/10.1096/...
faseb.onlinelibrary.wiley.com/doi/10.1096/...
Whole‐Gut Spatial Genomic Analysis Reveals Molecular Regionalization of the Differentiating Zebrafish Enteric Nervous System
Spatial genomic analysis of the developing enteric nervous system in zebrafish through multiplex whole mount HCR in slide identified genes that have temporal and spatial expression patterns during de...
faseb.onlinelibrary.wiley.com
September 5, 2025 at 1:09 PM
Check out our new work led by @rodrigomorec.bsky.social published today! We show that sequential, multiplexed HCR in whole-mount larval zebrafish revealed 3D spatial gene expression groups at the cellular and gut-levels in the enteric nervous system!
faseb.onlinelibrary.wiley.com/doi/10.1096/...
faseb.onlinelibrary.wiley.com/doi/10.1096/...
Check out our new work led by @rodrigomorec.bsky.social published today! We show that sequential, multiplexed HCR in whole-mount larval zebrafish revealed 3D spatial gene expression groups at the cellular and gut-levels in the enteric nervous system!
faseb.onlinelibrary.wiley.com/doi/10.1096/...
faseb.onlinelibrary.wiley.com/doi/10.1096/...
Whole‐Gut Spatial Genomic Analysis Reveals Molecular Regionalization of the Differentiating Zebrafish Enteric Nervous System
Spatial genomic analysis of the developing enteric nervous system in zebrafish through multiplex whole mount HCR in slide identified genes that have temporal and spatial expression patterns during de...
faseb.onlinelibrary.wiley.com
September 5, 2025 at 1:09 PM
Check out our new work led by @rodrigomorec.bsky.social published today! We show that sequential, multiplexed HCR in whole-mount larval zebrafish revealed 3D spatial gene expression groups at the cellular and gut-levels in the enteric nervous system!
faseb.onlinelibrary.wiley.com/doi/10.1096/...
faseb.onlinelibrary.wiley.com/doi/10.1096/...
What are some good Photoshop and Illustrator alternatives?
September 3, 2025 at 12:17 AM
What are some good Photoshop and Illustrator alternatives?
Reposted by Rosa Uribe, PhD
Cytoneme feedback ensures signaling specificity when multiple ligands converge on a common receptor https://www.biorxiv.org/content/10.1101/2025.08.28.672500v1
September 2, 2025 at 11:32 PM
Cytoneme feedback ensures signaling specificity when multiple ligands converge on a common receptor https://www.biorxiv.org/content/10.1101/2025.08.28.672500v1
Reposted by Rosa Uribe, PhD
Characterization of cis-regulatory elements and functional variants in colorectal cancer using epigenomics and CRISPRi screenings.
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Characterization of cis-regulatory elements and functional variants in colorectal cancer using epigenomics and CRISPRi screenings - Nature Cancer
Lu et al. characterize cis-regulatory element dynamics at different stages of colorectal cancer progression and identify a functional variant associated with increased colorectal cancer risk because o...
www.nature.com
August 29, 2025 at 12:27 PM
Characterization of cis-regulatory elements and functional variants in colorectal cancer using epigenomics and CRISPRi screenings.
www.nature.com/articles/s43...
www.nature.com/articles/s43...
Reposted by Rosa Uribe, PhD
Very proud to say that on Thursday August 21st I successfully defended my thesis!! I'm very thankful to @uribelab.bsky.social for being an amazing mentor through all the ups and downs.
Late last week, the 5th PhD student from my lab defended their thesis! Below is a "time lapse" of the traditional Rice University tie-cutting ceremony at Valhalla 🍾 👔 Congratulations, Dr. Rivas! We couldn't be prouder!
August 27, 2025 at 9:42 PM
Very proud to say that on Thursday August 21st I successfully defended my thesis!! I'm very thankful to @uribelab.bsky.social for being an amazing mentor through all the ups and downs.