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Zachary Brennan @zacharybrennan.bsky.social · 3d

Scoop: FDA confirms it's shaking up its university collaborations this year, under what's known as its CERSI program (5-yr, $50M collabs w/the likes of Hopkins, MD, UCSF-Stanford, Yale-Mayo Clinic) - endpoints.news/fda-to-rewor...

FDA to rework 'CERSI' university collaborations, will make funding changes

FDA plans to redesign its Centers for Excellence in Regulatory Science and Innovation program in 2026, affecting partnerships with Johns Hopkins, Yale, Mayo Clinic and others.

endpoints.news

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Amy Maxmen, PhD @amymaxmen.bsky.social · Sep 2

The CDC is an emergency response agency, whether that means responding to a cancer cluster, a measles outbreak, lead poisoning or the next pandemic.

I spoke with @cnn.com about how chaos there jeopardizes the country. kffhealthnews.org/news/article...

Watch: How Concerns of CDC Scientists Over Political Interference Have Grown This Year - KFF Health News

KFF Health News correspondent Amy Maxmen traces the political turmoil at the CDC under President Donald Trump.

kffhealthnews.org

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Sarah Karlin-Smith @sarahkarlin-smith.bsky.social · Sep 2

more vertical integration in health care... Cigna invests in Shields Health Solutions a specialty pharmacy company that just acquired the PE firm that just acquired Walgreens...

the web of connections is a bit headspinning...

nam04.safelinks.protection.outlook.com?url=https%3A...

Evernorth Health Services Announces Investment in Shields Health Solutions

Investment Further Enhances Evernorth's Participation in Growing Market for Specialty Medicine BLOOMFIELD, Conn., Sept. 2, 2025 /PRNewswire/ -- Evernorth Health Services ("Evernorth"), a...

nam04.safelinks.protection.outlook.com

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Renee DiResta @noupside.bsky.social · Sep 2

Vinay Prasad had YouTube censor Jonathan Howard’s channel because he didn’t like how it made him look.

A petty act by a vindictive, unqualified hack. And more evidence that these frEe sPeEcH warriors have always been petty censors out to silence criticism that they just can’t cope with.

Jonathan Howard @joho.bsky.social · Aug 29

My YouTube channel has like 300 followers and 99% of it is just videos of our medical establishment.

Today, I learned they are trying to censor me, instead of doing their job.

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Greg Folkers @gregfolkers.bsky.social · Aug 14

Endpoints: Kennedy pledges support for mRNA cancer vaccines despite decrying mRNA for Covid

by @zacharybrennan.bsky.social

bit.ly/41ztoTm

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Derek Lowe @dereklowe.bsky.social · Aug 5

This is a crime.

I can’t put it any other way.

Helen Branswell 🇨🇦 @helenbranswell.bsky.social · Aug 5

Pandemic preparedness in the US has been leveled a crippling blow with the cancellation of multiple #BARDA contracts to help develop mRNA vaccines. No other vaccine platform produces vaccine so quickly; without mRNA, Americans will have a long wait for pandemic vax. www.statnews.com/2025/08/05/m...

Health secretary RFK Jr. shuts door on U.S. investment in mRNA vaccine research

Vaccine experts and people steeped in pandemic preparedness expressed horror at the news that RFK Jr. has shut the door in U.S. investment in mRNA vaccine research.

www.statnews.com

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Robert Califf @robcaliff.bsky.social · Aug 5

This is ominous.

open.substack.com/pub/pauloffi...

RFK Jr.’s Plan to Eliminate Vaccines

Think VICP

open.substack.com

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ProPublica @propublica.org · Jul 7

NEW: With deep job cuts at the FDA, inspectors say the ongoing strain could compromise policing an industry spread across more than 90 countries.

“Things will be missed, we are going to have a lot less safe drugs,” a former inspector said.

FDA Layoffs Could Compromise Safety of Medications Made at Foreign Factories, Inspectors Say

Beyond staff cuts, the departures of some longtime investigators in recent months have left less experienced people tasked with rooting out dangerous manufacturing practices.

www.propublica.org

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Zachary Brennan @zacharybrennan.bsky.social · Jun 24

6 (from today). RFK says he made no promises to Cassidy

Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · Jun 24

Bill Cassidy and RFK Jr: A Short Story

1. Cassidy says that RFK Jr. will keep ACIP intact

2. RFK Jr. fires every member of ACIP

3. Cassidy says he will talk to RFK Jr. to ensure RFK Jr. appoints qualified people to ACIP

4. RFK Jr. appoints quacks

5. Cassidy wants to delay ACIP meeting

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Jason L. Schwartz @jasonlschwartz.bsky.social · Jun 18

Things are very bad for U.S. vaccination policy these days and are only going to get worse. In @nejm.org, I examine the recent news about COVID-19 vaccines and ACIP, what likely lies ahead, and what the medical and public health communities should do to lessen the damage www.nejm.org/doi/full/10....

Revised Recommendations for Covid-19 Vaccines — U.S. Vaccination Policy under Threat | NEJM

A series of recent actions by the Trump administration upend the country’s approach to Covid-19 vaccination and may portend a broader shift in the government’s role in protecting the public health.

www.nejm.org

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Mike Stobbe @mikestobbe.bsky.social · Jun 18

New CDC advisers will skip some expected topics and explore a target of antivaccine activists apnews.com/article/acip...

New CDC advisers will skip some expected topics and explore a target of antivaccine activists

U.S. Health Secretary Robert F. Kennedy Jr.’s new vaccine advisers meet next week. Their agenda suggests they’ll skip some expected topics, including a vote on COVID-19 shots.

apnews.com

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Apoorva Mandavilli @apoorvanyt.bsky.social · Jun 18

BREAKING: The FDA has approved a twice-yearly injection that provided a near-perfect shield against H.I.V. infection in clinical trials. But the Trump administration has gutted the programs that might have paid for it in low-income countries
(Gift article)

www.nytimes.com/2025/06/18/h...

Regulators Approve a Twice-Yearly Shot to Prevent H.I.V. Infection

www.nytimes.com

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Zachary Brennan @zacharybrennan.bsky.social · Jun 17

👀

Sarah Karlin-Smith @sarahkarlin-smith.bsky.social · Jun 17

Makary says reason he is doing his CEO forums privately is so CEOs can be honest and don't have to worry about shareholders think. #BIO2025

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Kai Kupferschmidt @kakape.bsky.social · Jun 11

Feeling a lot like I did in early days of the pandemic these days. It is so clear what’s coming: The people that will die because of cuts in global health, because of cuts to research, because of the concerted anti-vaccine push.
It’s clear what’s coming, but we will have to wait to count the dead.🧪

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JAMA @jama.com · Jun 9

Viewpoint: The FDA's non-standard review of Novavax's #COVID19 vaccine raises concerns about regulatory integrity and the influence of political considerations on public health decisions.

https://ja.ma/3TepavL

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Ted Pavlic (he/him/his) @tedpavlic.bsky.social · Jun 8

Reminder: Nobel-prize winning PCR (1983), used in basically all genetic tech today, was only possible because of extremophile bacterium discovered in 1964 in Yellowstone funded by a small ~$80k NSF grant with no obvious application at the time. #science 🧪
www.richmondscientific.com/how-a-discov...

How a discovery in Yellowstone National Park led to the development of PCR - Richmond Scientific

A discovery in Yellowstone National Park led to the development of PCR, the gold-standard COVID-19 tests used to fight the global pandemic.

www.richmondscientific.com

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Zachary Brennan @zacharybrennan.bsky.social · Jun 9

the 10 out, 1 in policy is agency-wide, not at all specific to cell/gene therapies and there was no mention at that meeting of deregulating or changing any regs (RFK was talking about adding some, and asking for requests/lists on which to cut)

Ally Whelan @amwhelan.bsky.social · Jun 8

RFK Jr's tenure at HHS is shaping up to be one of inconsistent, nonsensical, and dangerous overregulation (see, e.g., vaccines) and underregulation (see, gene and cell therapies)

Leigh Turner @leighturner.bsky.social · Jun 8

“President Trump has given us an executive order that says for every regulation that we put in place, we have to get rid of 10." HHS & FDA apparently moving forward with broad deregulatory agenda for cell & gene-based medical interventions. www.fiercebiotech.com/biotech/fda-...

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Helen Branswell 🇨🇦 @helenbranswell.bsky.social · Jun 6

So it looks like #ACIP will be meeting later this month.
It will be interesting.
🍿
public-inspection.federalregister.gov/2025-10432.pdf

public-inspection.federalregister.gov

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Larry Levitt @larrylevitt.bsky.social · Jun 4

An increase of 10.9 million uninsured people, plus millions of others who will lose coverage if enhanced ACA premium tax credits expire this year, would reverse much of the gains in insurance coverage from the ACA.

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Berkeley Lovelace Jr. @berkeleyjr.bsky.social · Jun 3

NEW - A new FDA AI tool that could speed up reviews of medical devices is struggling with simple tasks, like uploading documents, according to two people familiar.

A separate tool, called Elsa, which was rolled out to FDA employees Monday is also having issues.

www.nbcnews.com/health/healt...

FDA’s AI tool for medical devices struggles with simple tasks

On Monday, the agency announced that a separate AI tool, called Elsa, had been rolled out to all FDA employees. Sources say that it also has issues.

www.nbcnews.com

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Zachary Brennan @zacharybrennan.bsky.social · Jun 3

Meet the FDAers who were cut by DOGE but still get paid in full w/benefits as they look for new work (going on month 3 now..) endpoints.news/laid-off-fda...

DOGE set today as their last day at FDA. Instead, they're continuing to get full pay and don't work

FDA lawyer and other federal health agency workers remain on paid leave amid Trump administration cuts, awaiting court decisions while searching for new jobs.

endpoints.news

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Alexander Tin @alexander-a-tin.bsky.social · May 30

For pregnant women, CDC now lists COVID-19 vaccines during pregnancy as "No Guidance/Not Applicable"

www.cdc.gov/vaccines/hcp...

A screenshot of a table that reads: "Ages 19 Years or Older Legend Recommended vaccination for adults who meet age requirement, lack documentation of vaccination, or lack evidence of immunity Recommended vaccination for adults with an additional risk factor or another indication Recommended vaccination based on shared clinical decision-making No Guidance/Not Applicable Vaccine Pregnancy Immuno-compromised (excluding HIV infection) HIV infection CD4 percentage and count Men who have sex with men Asplenia, complement deficiency Heart or lung disease Kidney failure, End-stage renal disease or on dialysis Chronic liver disease; alcoholisma Diabetes Health care Personnelb <15% or <200/mm3 ≥15% and ≥200/mm3 COVID-19 more info icon. See Notes"

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Mehdi Hasan @mehdirhasan.bsky.social · May 29

This is what happens when you put internet conspiracy theorists in charge of major government departments.

The MAHA Report Cites Studies That Don’t Exist

The Trump administration’s “Make America Healthy Again” report misinterprets some studies and cites others that don’t exist, according to the listed authors.

www.notus.org

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Sarah Karlin-Smith @sarahkarlin-smith.bsky.social · May 27

If someone has to read halfway through your story before finding out Kennedy's step on COVID vaccination today is not in alignment with the scientific evidence you are doing it wrong.

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Robert Califf @robcaliff.bsky.social · May 27

These ACOG views were based on a significant studies. it will be interesting to see if the recommendation against vaccination is based on new evidence or some kind of interpretation of the old evidence.

www.acog.org/news/news-re...

ACOG Statement on HHS Recommendations Regarding the COVID Vaccine During Pregnancy

ACOG strongly opposes the U.S. Department of Health and Human Services' decision to stop recommending the COVID vaccination during pregnancy, citing clear evidence of its safety and effectiveness in p...

www.acog.org

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