Alfonso Martinez Arias
@amartinezarias.bsky.social
1.5K followers 310 following 330 posts
Interested in how cells use genes to create shape, form and function in #embryos as well as in Societal Wellbeing #NotInTheGenes #InNumbersWeTrust #gastruloids #gastrulation
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Reposted by Alfonso Martinez Arias
jacob-hanna.bsky.social
A Palestinian, son of Palestinians displaced from Gaza (Al-Masmiyya) to Jordan, wins the Nobel Prize in Chemistry... Professor Omar Munis Yaghi from the University of Berkeley!!

..Some members of the Yaghi family are still under the rubble in Gaza!
amartinezarias.bsky.social
Yes, the beautiful pre-drawn drawings are legendary
amartinezarias.bsky.social
John Gurdon en.wikipedia.org/wiki/John_Gu..., beacon of a generation that tackled head on the deepest question of biology: the development of an organism. The best tribute to him and his peers should be to remember and follow the path they forged for how to do Science in form and content.
Reposted by Alfonso Martinez Arias
mrsantos.bsky.social
John Gurdon was a true giant:
- founder of cell reprogramming;
- founder of molecular embryology;
- unabashed advocate for basic research;
- advisor to numerous successful trainees/PIs;
- gentle human that touched so many.
In dark times with science under attack, let his vision be a guiding light.
katherine-brown.bsky.social
Very saddened to hear of John Gurdon’s passing. I’ve been lucky enough to interact with him at multiple points through my career - from undergrad lectures, through his position as former Chair of @biologists.bsky.social’s Board of Directors, and as an author at @dev-journal.bsky.social.
Nobel Laureate Professor Sir John Gurdon dies aged 92
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.
www.cam.ac.uk
amartinezarias.bsky.social
Organizing time past, remembered this summary of many thoughts that I continue to pursue
And nowhere rings more true that ‘the detail of pattern is the movement’ than in the actions of cells as they build #embryos
www.youtube.com/watch?v=bbQV...
#CellsRUs #MasterBuilder
Landscapes and embryos : A film from A. Martinez Arias
YouTube video by Cambridge University
www.youtube.com
Reposted by Alfonso Martinez Arias
richardsever.bsky.social
Another record month for bioRxiv - and further evidence the pandemic spike+dip was just that and growth continues. Thanks to all involved and that includes 🫵
amartinezarias.bsky.social
Today is a special day, some would call it the first of the rest of my life.
I look forward to doing the same as before, from a different vantage point, trying to use what I have learnt to keep on learning. Thank you to all who have taught me.
#NotInTheGenes #CellsRUs
Reposted by Alfonso Martinez Arias
cellsdev.bsky.social
In this intriguing paper published from the lab of @amartinezarias.bsky.social , they looked at the effects of size on morphology, tissue composition, and gene expression of gastruloid development. They found that AP elongation dynamics is size-dependent! Check it out here:
doi.org/10.1016/j.cd...
amartinezarias.bsky.social
Human Reproductive biology is an important area in need of funding support and we need to rise to this challenge. #IVF as they best technologies develops best when it looks for its roots in #DevBio as shown by the work of R. Edwards.
amartinezarias.bsky.social
The second phase (1972-1978, Louise Brown’s birth) required the combination of the earlier #DevBio with gynecology and endocrinology. This is when it drifts into technology and mauve loses the limelight of basic biology.
amartinezarias.bsky.social
Furthermore, it is this work that enabled research into early human development, derivation of pluripotent stem cells and Stem Cell based Embryo Models #SCBEMs.
amartinezarias.bsky.social
There are two periods to Edwards work. First, 1961-1971, is all about developmental biology. Egg maturation, fertilization and most significantly growth of the zygote into a blastocyst are landmarks in #DevBio.
amartinezarias.bsky.social
This needs to change and a way to change it is to acknowledge that #IVF is about #DevBio
amartinezarias.bsky.social
Research into #IVF is not as well funded as it should be. The reasons are unclear but one wonders if part of the reason might not lie in the perception that it is a health technology and not a medical priority.
amartinezarias.bsky.social
This is a good opportunity to reflect on what many people deem a technique addressing issues of human fertility but is a blend of different disciplines w/ DevBio at the center. It is important to acknowledge that all IVF issues are about #DevBio.
amartinezarias.bsky.social
For a good summary of the history of #IVF and Edwards see ijdb.ehu.eus/article/1803...
amartinezarias.bsky.social
Today is the 100th anniversary of the birth of Robert Edwards, #IVF pioneer and someone who, unknowingly, bridged #DevBio #Gynecology and Endocrinology in a highly successful manner.
amartinezarias.bsky.social
#gastruloids by the shores of Lake Lehman, Lausanne 2017
The start of something
@EPFL @geneticscam.bsky.social
amartinezarias.bsky.social
Liked Netflix version of #IlGatopardo, a good interpretation of the book w/ much that measures well v Visconti’s original but the exception is Angelica who was and is Claudia Cardinale
www.youtube.com/watch?v=UVS_...
entrata angelica
YouTube video by Rosanna Tuosto
www.youtube.com
amartinezarias.bsky.social
Life and Science go on, with more freedom and time to enjoy the stations along the way V7.0s are robust
Reposted by Alfonso Martinez Arias
cahirokane.bsky.social
A privilege and delight to attend this meeting last week. A reminder that science, as well as development, is done by communities.
amartinezarias.bsky.social
THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
Reposted by Alfonso Martinez Arias
eliasbarrigalab.bsky.social
Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!
amartinezarias.bsky.social
THANK YOU for many years of friendship, support and for sharing your great Science
La Pedrera #Barcelona
#NotInTheGenes #CellsRUs #Cambridge
Reposted by Alfonso Martinez Arias
nmoris.bsky.social
Marvellous send off for @amartinezarias.bsky.social ‘s lab, perfectly located in Gaudi’s La Pedrera. I took no pictures as I was too busy hugging old friends, but the organisers incl @dias-andre.bsky.social pulled off something rly special. Community in science is the real joy of the work we do! 💕
A PowerPoint slide with a gastruloid on a mosaic tile background Photo of the inside of Gaudi’s La Pedera building with decorative railings and mosaic painted walls Naomi Moris hugs Meena Chakrabuty Alfonso Martinez Arias giving a closing speech at dinner
amartinezarias.bsky.social
With the group that came together @upf.edu in #Barcelona, celebrating 5 years of exploring, dreaming and discovering. Grateful #NotInTheGenes #CellsRUs