Dana Davis Phf’nD
@angrybychoice.bsky.social
Micro prof interested in fungi, evolution, environmental adaptation.
Reposted by Dana Davis Phf’nD
Age-specific genomic and transcriptomic variation reveals limited evidence for cis-regulatory interactions modulating aging in Saccharomyces cerevisiae https://www.biorxiv.org/content/10.64898/2025.12.12.689579v1
December 15, 2025 at 12:33 AM
Age-specific genomic and transcriptomic variation reveals limited evidence for cis-regulatory interactions modulating aging in Saccharomyces cerevisiae https://www.biorxiv.org/content/10.64898/2025.12.12.689579v1
Reposted by Dana Davis Phf’nD
Microbial eukaryotes keep challenging assumptions about eukaryotic cell and genome biology.
Our upcoming workshop explores the frontier of protist genomics and how it shapes cell biology, ecology and evolution.
Please save the date! Talks, posters and ECR events
Websites and details coming soon
Our upcoming workshop explores the frontier of protist genomics and how it shapes cell biology, ecology and evolution.
Please save the date! Talks, posters and ECR events
Websites and details coming soon
December 13, 2025 at 10:19 AM
Microbial eukaryotes keep challenging assumptions about eukaryotic cell and genome biology.
Our upcoming workshop explores the frontier of protist genomics and how it shapes cell biology, ecology and evolution.
Please save the date! Talks, posters and ECR events
Websites and details coming soon
Our upcoming workshop explores the frontier of protist genomics and how it shapes cell biology, ecology and evolution.
Please save the date! Talks, posters and ECR events
Websites and details coming soon
Going to be butt ass cold in Minneapolis tomorrow, it would suck if ICE got splashed with lots of water. I do not recommend.
December 13, 2025 at 3:25 AM
Going to be butt ass cold in Minneapolis tomorrow, it would suck if ICE got splashed with lots of water. I do not recommend.
Reposted by Dana Davis Phf’nD
DOJ has sued Maine, Oregon, California, Michigan, Minnesota, New York, New Hampshire, Pennsylvania, Washington, Delaware, Maryland, New Mexico, Rhode Island, and Vermont for access to its most sensitive voter data.
My firm has moved to intervene in 10 of those cases. We are working on the last 4.
My firm has moved to intervene in 10 of those cases. We are working on the last 4.
December 12, 2025 at 5:29 PM
DOJ has sued Maine, Oregon, California, Michigan, Minnesota, New York, New Hampshire, Pennsylvania, Washington, Delaware, Maryland, New Mexico, Rhode Island, and Vermont for access to its most sensitive voter data.
My firm has moved to intervene in 10 of those cases. We are working on the last 4.
My firm has moved to intervene in 10 of those cases. We are working on the last 4.
Reposted by Dana Davis Phf’nD
🧬 November's most-read Genetics paper shows pathogenicity in fungi is better predicted by the number of protein-coding genes than by repeat content: buff.ly/jnv5l9J
Have a paper people should see? See what our Editors look for: buff.ly/45eBsQ1
Have a paper people should see? See what our Editors look for: buff.ly/45eBsQ1
December 11, 2025 at 9:02 PM
🧬 November's most-read Genetics paper shows pathogenicity in fungi is better predicted by the number of protein-coding genes than by repeat content: buff.ly/jnv5l9J
Have a paper people should see? See what our Editors look for: buff.ly/45eBsQ1
Have a paper people should see? See what our Editors look for: buff.ly/45eBsQ1
Last class of the semester in the books, time to celebrate….after faculty meeting 🤪
December 10, 2025 at 8:36 PM
Last class of the semester in the books, time to celebrate….after faculty meeting 🤪
Reposted by Dana Davis Phf’nD
Federal agents are arresting American citizens.
This isn’t about public safety - it’s about stoking fear.
www.mprnews.org/story/2025/1...
This isn’t about public safety - it’s about stoking fear.
www.mprnews.org/story/2025/1...
Federal agents arrest citizen observer watching ICE detain neighbors on her north Minneapolis block
Susan Tincher, a 55-year-old American citizen, appears to be the first observer arrested by federal immigration enforcement officers since the agency launched an immigration surge in the Twin Cities l...
www.mprnews.org
December 10, 2025 at 3:19 PM
Federal agents are arresting American citizens.
This isn’t about public safety - it’s about stoking fear.
www.mprnews.org/story/2025/1...
This isn’t about public safety - it’s about stoking fear.
www.mprnews.org/story/2025/1...
Wordle 1,634 3/6
⬛⬛🟨🟨⬛
🟩⬛⬛⬛🟩
🟩🟩🟩🟩🟩
Damn straight
⬛⬛🟨🟨⬛
🟩⬛⬛⬛🟩
🟩🟩🟩🟩🟩
Damn straight
December 10, 2025 at 2:26 AM
Wordle 1,634 3/6
⬛⬛🟨🟨⬛
🟩⬛⬛⬛🟩
🟩🟩🟩🟩🟩
Damn straight
⬛⬛🟨🟨⬛
🟩⬛⬛⬛🟩
🟩🟩🟩🟩🟩
Damn straight
Reposted by Dana Davis Phf’nD
Metabolism: How pyruvate controls cell size
🔗 eLife Insight Articles delve into the real significance of the latest research. Read here: buff.ly/F3gMKka.
🔗 eLife Insight Articles delve into the real significance of the latest research. Read here: buff.ly/F3gMKka.
December 8, 2025 at 9:02 PM
Metabolism: How pyruvate controls cell size
🔗 eLife Insight Articles delve into the real significance of the latest research. Read here: buff.ly/F3gMKka.
🔗 eLife Insight Articles delve into the real significance of the latest research. Read here: buff.ly/F3gMKka.
Reposted by Dana Davis Phf’nD
Most definitely!
And we’ve got a new curriculum that addresses AI specifically:
And we’ve got a new curriculum that addresses AI specifically:
Modern-Day Oracles or Bullshit Machines: Introduction
A free online humanities course about how to learn and work and thrive in an AI world.
Thebullshitmachines.com
December 7, 2025 at 5:07 PM
Most definitely!
And we’ve got a new curriculum that addresses AI specifically:
And we’ve got a new curriculum that addresses AI specifically:
Wordle 1,633 4/6
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
🟩🟩⬜⬜🟩
🟩🟩🟩🟩🟩
Who needs yellow
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
🟩🟩⬜⬜🟩
🟩🟩🟩🟩🟩
Who needs yellow
December 8, 2025 at 1:50 PM
Wordle 1,633 4/6
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
🟩🟩⬜⬜🟩
🟩🟩🟩🟩🟩
Who needs yellow
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
🟩🟩⬜⬜🟩
🟩🟩🟩🟩🟩
Who needs yellow
Reposted by Dana Davis Phf’nD
Flagellar length control in Chlamydomonas is a paradigm for organelle size regulation. In poster 155 at the CellBio2025 meeting Sunday Dec 7, Ximena Garcia Arceo uses Lithium, which increases intraflagellar transport, as a tool to probe how length-altering mutants work.
December 7, 2025 at 3:43 AM
Flagellar length control in Chlamydomonas is a paradigm for organelle size regulation. In poster 155 at the CellBio2025 meeting Sunday Dec 7, Ximena Garcia Arceo uses Lithium, which increases intraflagellar transport, as a tool to probe how length-altering mutants work.
Wordle 1,631 2/6
🟩⬛⬛🟩🟩
🟩🟩🟩🟩🟩
Well, I’m guessing I won’t be getting it in 1 anytime soon unless I change my starting word
🟩⬛⬛🟩🟩
🟩🟩🟩🟩🟩
Well, I’m guessing I won’t be getting it in 1 anytime soon unless I change my starting word
December 6, 2025 at 11:59 AM
Wordle 1,631 2/6
🟩⬛⬛🟩🟩
🟩🟩🟩🟩🟩
Well, I’m guessing I won’t be getting it in 1 anytime soon unless I change my starting word
🟩⬛⬛🟩🟩
🟩🟩🟩🟩🟩
Well, I’m guessing I won’t be getting it in 1 anytime soon unless I change my starting word
Reposted by Dana Davis Phf’nD
"Our results enable us to reject mitochondrion-early scenarios of eukaryogenesis, instead supporting a complexified-archaean, late-mitochondrion sequence for the assembly of eukaryote characteristics"
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Dated gene duplications elucidate the evolutionary assembly of eukaryotes - Nature
Analysis of eukaryotic gene sequences using a relaxed molecular clock methodology indicate that eukaryotes emerged 3.0–2.25 billion years ago as a result of mitochondrial endosymbiosis with complex ar...
www.nature.com
December 3, 2025 at 10:14 PM
"Our results enable us to reject mitochondrion-early scenarios of eukaryogenesis, instead supporting a complexified-archaean, late-mitochondrion sequence for the assembly of eukaryote characteristics"
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Dana Davis Phf’nD
Thorholludottir, D. A. V., Hsu, S. K., Barghi, N., Mallard, F., Nolte, V., Schlotterer, C. (2025). Reduced Parallel Gene Expression Evolution With Increasing Genetic Divergence-A Hallmark of Polygenic Adaptation. Mol Ecol, 34(12):e17803 onlinelibrary.wiley.com/doi/10.1111/...
December 3, 2025 at 11:29 PM
Thorholludottir, D. A. V., Hsu, S. K., Barghi, N., Mallard, F., Nolte, V., Schlotterer, C. (2025). Reduced Parallel Gene Expression Evolution With Increasing Genetic Divergence-A Hallmark of Polygenic Adaptation. Mol Ecol, 34(12):e17803 onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Dana Davis Phf’nD
A recent shift in centromere size and DNA content in Podospora pseudocomata co-occurs with the loss of a fungal genome defense system https://www.biorxiv.org/content/10.64898/2025.12.02.690432v1
December 3, 2025 at 2:31 AM
A recent shift in centromere size and DNA content in Podospora pseudocomata co-occurs with the loss of a fungal genome defense system https://www.biorxiv.org/content/10.64898/2025.12.02.690432v1
Reposted by Dana Davis Phf’nD
www.embopress.org/doi/full/10....
Our latest now online at EMBO Journal. Read if you are interested in how epimutations mediate antifungal resistance & how this might result in heteroresistance in human & cereal crop fungal pathogens. Big Thx & congrats to Andreas Fellas, Pin Tong & Alison Pidoux
Our latest now online at EMBO Journal. Read if you are interested in how epimutations mediate antifungal resistance & how this might result in heteroresistance in human & cereal crop fungal pathogens. Big Thx & congrats to Andreas Fellas, Pin Tong & Alison Pidoux
Heterochromatin epimutations impose mitochondrial dysfunction to confer antifungal resistance | The EMBO Journal
imageimageHeterochromatin-island epimutations can provide resistance to caffeine and antifungal
drugs in the fission yeast Schizosaccharomyces pombe. This study reveals that some epimutations cause re...
www.embopress.org
December 1, 2025 at 3:44 PM
www.embopress.org/doi/full/10....
Our latest now online at EMBO Journal. Read if you are interested in how epimutations mediate antifungal resistance & how this might result in heteroresistance in human & cereal crop fungal pathogens. Big Thx & congrats to Andreas Fellas, Pin Tong & Alison Pidoux
Our latest now online at EMBO Journal. Read if you are interested in how epimutations mediate antifungal resistance & how this might result in heteroresistance in human & cereal crop fungal pathogens. Big Thx & congrats to Andreas Fellas, Pin Tong & Alison Pidoux
Reposted by Dana Davis Phf’nD
It’s #MeiofaunaMonday! “Meiofauna” are microbial eukaryotes with a body size <1 mm (these animals and protists are as small as specks of dust you might see on a glass coffee table). Almost all of the 38 major animal groups have at least some small-bodied meiofauna species.
December 1, 2025 at 3:16 PM
It’s #MeiofaunaMonday! “Meiofauna” are microbial eukaryotes with a body size <1 mm (these animals and protists are as small as specks of dust you might see on a glass coffee table). Almost all of the 38 major animal groups have at least some small-bodied meiofauna species.
Study section meets in late Jan. Two more months to hear my proposal didn’t meet the 30% bar.
December 2, 2025 at 12:55 PM
Study section meets in late Jan. Two more months to hear my proposal didn’t meet the 30% bar.
Wordle 1,624 5/6
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
🟩🟩🟩🟩🟩
A tree grows in Brooklyn
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
🟩🟩🟩🟩🟩
A tree grows in Brooklyn
November 29, 2025 at 3:09 PM
Wordle 1,624 5/6
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
🟩🟩🟩🟩🟩
A tree grows in Brooklyn
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
⬜🟩⬜⬜⬜
🟩🟩🟩🟩🟩
A tree grows in Brooklyn
Thanksgiving weekend for me, recovering from surgery (fairly minor) playing Hades and Death Stranding…so far
November 28, 2025 at 9:38 PM
Thanksgiving weekend for me, recovering from surgery (fairly minor) playing Hades and Death Stranding…so far
Amazing work first worked on in a ciliate, tetrahymena, that has two functionally distinct nuclei. One of these the macronucleus contains many fragmented copies of the genome and every fragmented piece has telomeres on both ends. This oddity of biology made it relatively easy to identify.
Biochemist Dr. Elizabeth Blackburn was born #OTD in 1948.
She shared the 2009 #Nobel Prize in Physiology or Medicine for the discovery of the enzyme telomerase & how chromosomes are protected by telomeres. This has 𝘮𝘰𝘯𝘶𝘮𝘦𝘯𝘵𝘢𝘭 implications for the fields of #aging and #cancer research. #WomenInSTEM
She shared the 2009 #Nobel Prize in Physiology or Medicine for the discovery of the enzyme telomerase & how chromosomes are protected by telomeres. This has 𝘮𝘰𝘯𝘶𝘮𝘦𝘯𝘵𝘢𝘭 implications for the fields of #aging and #cancer research. #WomenInSTEM
November 27, 2025 at 7:53 PM
Amazing work first worked on in a ciliate, tetrahymena, that has two functionally distinct nuclei. One of these the macronucleus contains many fragmented copies of the genome and every fragmented piece has telomeres on both ends. This oddity of biology made it relatively easy to identify.
Reposted by Dana Davis Phf’nD
Fun new preprint from the lab, headed up by two incredible undergraduate researchers: Using Experimental Evolution to Correct Mother-Daughter Separation Defects in Brewing Yeast. www.biorxiv.org/content/10.1...
Using Experimental Evolution to Correct Mother-Daughter Separation Defects in Brewing Yeast
The budding yeast, Saccharomyces cerevisiae, is the workhorse of the brewing industry. Brewers have domesticated a vast array of different strains with traits that complement the beers they wish to br...
www.biorxiv.org
November 26, 2025 at 8:18 PM
Fun new preprint from the lab, headed up by two incredible undergraduate researchers: Using Experimental Evolution to Correct Mother-Daughter Separation Defects in Brewing Yeast. www.biorxiv.org/content/10.1...
Reposted by Dana Davis Phf’nD
www.nature.com/articles/s41...
Progressive coevolution of the yeast centromere and kinetochore
🤩
@helsenjana.bsky.social @gautamdey.bsky.social
Progressive coevolution of the yeast centromere and kinetochore
🤩
@helsenjana.bsky.social @gautamdey.bsky.social
Progressive coevolution of the yeast centromere and kinetochore - Nature
Thousands of centromeres were identified and tracked across two major fungal clades, showing that new centromeres spread progressively and that the kinetochore acts as a filter to determine which new ...
www.nature.com
November 27, 2025 at 6:22 PM
www.nature.com/articles/s41...
Progressive coevolution of the yeast centromere and kinetochore
🤩
@helsenjana.bsky.social @gautamdey.bsky.social
Progressive coevolution of the yeast centromere and kinetochore
🤩
@helsenjana.bsky.social @gautamdey.bsky.social
Reposted by Dana Davis Phf’nD
📢 NEW GENOME ALERT
Latest study in #G3journal shows high-quality genomes of P. mongolica and P. schrenkiana, fungi species known for forest decomposition, identifying genes responsible for lignocellulose decomposition. buff.ly/DYuyTyr
Latest study in #G3journal shows high-quality genomes of P. mongolica and P. schrenkiana, fungi species known for forest decomposition, identifying genes responsible for lignocellulose decomposition. buff.ly/DYuyTyr
November 27, 2025 at 7:08 PM
📢 NEW GENOME ALERT
Latest study in #G3journal shows high-quality genomes of P. mongolica and P. schrenkiana, fungi species known for forest decomposition, identifying genes responsible for lignocellulose decomposition. buff.ly/DYuyTyr
Latest study in #G3journal shows high-quality genomes of P. mongolica and P. schrenkiana, fungi species known for forest decomposition, identifying genes responsible for lignocellulose decomposition. buff.ly/DYuyTyr