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bjesseshapiro.bsky.social
Jesse Shapiro
@bjesseshapiro.bsky.social
1.7K followers 710 following 400 posts
Macrobe qui aime les microbes http://www.shapirolab.ca/
www.shapirolab.ca
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bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · Jul 1
One of my favourite serendipitous results from the lab came about because we were long-read sequencing bacterial:

Vibrio cholerae, which is "supposed to" have TWO circular chromosomes (3 + 1 million base pairs) often has just ONE fused chromosome (4 Mbp).

www.nature.com/articles/s41...

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Prevalent chromosome fusion in Vibrio cholerae O1 - Nature Communications
The pathogenic bacterium Vibrio cholerae typically has two circular chromosomes. Here, Cuénod et al. analyse 467 clinical isolates and identify several independent chromosome fusion events that are li...
www.nature.com
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bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 6h
Would love to. Let’s keep in touch.
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Reposted by Jesse Shapiro
kevindkohl.bsky.social
KevinDKohl @kevindkohl.bsky.social · 26d
Pleased to share new work tinkering with and testing the concept of the holobiont
@isme-microbes.bsky.social

"Experimental evolution of a mammalian holobiont: bank voles selected for herbivorous capability evolved distinct and robust gut bacterial communities"
🌾🐭🦠

academic.oup.com/ismecommun/a...
Experimental evolution of a mammalian holobiont: bank voles selected for herbivorous capability evolved distinct and robust gut bacterial communities
Abstract. According to the “hologenome” theory of evolution natural selection and evolution can act through a conglomerate biological unit, the “holobiont”
academic.oup.com
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bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 21h
Around Montpellier! Exact location TBA, depends on the quality of local bike routes ;)
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bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 21h
Fall 2026 to summer 2027! Want to come visit? Will you be nearby?
bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 22h
Sabbatical planning: step 1.
A photo of a cycling map of France on a table beside a glass of beer on a table in a bar.
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Reposted by Jesse Shapiro
drjdennehy.bsky.social
John Dennehy @drjdennehy.bsky.social · 1d
www.cell.com/trends/ecolo...

New entry into the Disability in Ecology and Evolution series in TREE featuring me :)
Disability in ecology and evolution
In this TrendsTalk series 'Disability in ecology and evolution' in Trends in Ecology and Evolution, we will be hearing from people about their experiences being disabled in ecology and evolution. We a...
www.cell.com
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Reposted by Jesse Shapiro
julietalbot.bsky.social
Julie Talbot @julietalbot.bsky.social · 1d
My department @geographieudem.bsky.social is looking for a professor in human geography specializing in the study of social-ecological transformations, political ecology, climate change, environmental justice and/or the geography of risks and infrastructures. Deadline November 10, share widely!
Glass buildings with a paved path in between (gray, with blue lines)
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Reposted by Jesse Shapiro
surtlab.bsky.social
Dave Baltrus 🦦 @surtlab.bsky.social · 1d
Here’s published version of our manuscript using GWAS to investigate tailocin sensitivity in Pseudomonas syringae. TL:DR pretty clear LPS is tailocin receptor but also that P.syringae often completely swaps out its entire O antigen biosynth pathway w/ recombination

academic.oup.com/g3journal/ad...
Genomic correlates of tailocin sensitivity in Pseudomonas syringae
Abstract. Phage-derived bacteriocins, also referred to as tailocins, are structures encoded by bacterial genomes and deployed into the extracellular enviro
academic.oup.com
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Reposted by Jesse Shapiro
brockhurstlab.bsky.social
Michael Brockhurst @brockhurstlab.bsky.social · 2d
New preprint!

Ever wondered why only a fraction of genomes encode CRISPR immunity? 🧬 🦠

Turns out CRISPR is rarely beneficial against virulent phages, being most beneficial against those for which resistance mutations are rare!

An epic effort by Rosanna Wright

www.biorxiv.org/content/10.1...
Resistance mutation supply modulates the benefit of CRISPR immunity against virulent phages
Only a fraction of bacterial genomes encode CRISPR-Cas systems but the selective causes of this variation are unexplained. How naturally virulent bacteriophages (phages) select for CRISPR immunity has...
www.biorxiv.org
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Reposted by Jesse Shapiro
evolvedbiofilm.bsky.social
Ákos T Kovács @evolvedbiofilm.bsky.social · 5d
Filamentous cheater phages drive bacterial and phage populations to lower fitness

Pseudomonas aeruginosa VS Pf phage

@currentbiology.bsky.social by @nanamikubota.bsky.social, @shellyscrib.bsky.social and @vscooper.micropopbio.org

www.cell.com/current-biol...

#PhageSky
Filamentous cheater phages drive bacterial and phage populations to lower fitness
Kubota et al. show that bacteria can use their filamentous phage to outcompete other bacteria, but increased phage production enables the evolution of cheater miniphages with truncated genomes. Miniph...
www.cell.com
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Reposted by Jesse Shapiro
currentbiology.bsky.social
Current Biology @currentbiology.bsky.social · 6d
Sad news: Jane Goodall has died. She did more than any other human for our understanding and appreciation of our closest relatives, the chimpanzees.

That chimpanzees are Endangered tells you everything about our species and about what made her so exceptional.

www.nytimes.com/2025/10/01/o...
Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91
www.nytimes.com
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Reposted by Jesse Shapiro
mcgill-microbiome.bsky.social
McGill Centre for Microbiome Research @mcgill-microbiome.bsky.social · 7d
The McGill Centre for Microbiome Research is hosting a mini-symposium Oct 21! Microbiome and Pain: Unraveling the Gut-Brain connection. Sign up for a great morning of student talks, networking and a keynote from Dr. David Bulmer! www.eventbrite.ca/e/microbiome...
Microbiome and Pain: Unraveling the Gut-Brain connection
Join us for this co-hosted half-day seminar with the Alan Edwards Centre for Research on Pain. Keynote speaker: Dr David Bulmer.
www.eventbrite.ca
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bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 7d
Hello October!
A corner grocery store with a plethora of pumpkins spilling out on the sidewalk, draped with fake cobwebs and other Halloween decorations.
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Reposted by Jesse Shapiro
craigmaclean.bsky.social
Craig MacLean @craigmaclean.bsky.social · 8d
New pre-print
Competition between phage constrains adaptation to thermal fluctuating temperatures.
More work led by Sam Greenrod in collaboration with @kayla-king.bsky.social lab.
#Phagesky#Microsky

www.biorxiv.org/content/10.1...
www.biorxiv.org
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Reposted by Jesse Shapiro
fabricejpierre.bsky.social
Fabrice Jean-Pierre @fabricejpierre.bsky.social · 8d
Plus que 10 jours avant la fin des soumissions des résumés pour le BiSP qui aura lieu le 5-6 novembre 2025 à l'Université de Sherbrooke. Nous aurons aussi la chance de recevoir @lalouxlab.bsky.social et @bjesseshapiro.bsky.social

Partagez! @micrhub.bsky.social

event.fourwaves.com/bispmicrhubs...
BiSP - MicrHub
Fourwaves - BiSP - MicrHub
event.fourwaves.com
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bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 11d
I can send photos next week. And DNA extracts if you want.
bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 12d
Yep. Evidence for kin selection in action.
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bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 12d
How did you get into our shared office kitchen without card access Willem?!
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bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 12d
Leaky pipes, happy trees!

www.montrealgazette.com/news/article...
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Reposted by Jesse Shapiro
carlsonlab.bsky.social
The Carlson Lab @ Yale @carlsonlab.bsky.social · 12d
🚨 We're about to start reviewing applications, but there's still time to reach out for our postdoc position on climate change impact attribution! If you have experience with attribution science or climate epidemiology, and want to help us launch the Global Burden of Climate Change Study, reach out!
yale's beautiful campus from overhead
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Reposted by Jesse Shapiro
zaminiqbal.bsky.social
Zamin Iqbal @zaminiqbal.bsky.social · 12d
Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
Thread 1/n
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bjesseshapiro.bsky.social
Jesse Shapiro @bjesseshapiro.bsky.social · 12d
Wow, superb thread Zam! I think we have our journal club paper for next week =)
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Reposted by Jesse Shapiro
mamassian.bsky.social
Pascal Mamassian @mamassian.bsky.social · 14d
A nice shift in perceived colour between central and peripheral vision. The fixated disc looks purple while the others look blue.

The effect presumably comes from the absence of S-cones in the fovea.

From Hinnerk Schulz-Hildebrandt:
arxiv.org/pdf/2509.115...
An array of 9 purple discs on a blue background. Figure from Hinnerk Schulz-Hildebrandt.
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Reposted by Jesse Shapiro
susankayequinn.bsky.social
Susan Kaye Quinn is Writing Solarpunk 🌞🌱 @susankayequinn.bsky.social · 14d
They've lost the 9yos
JA Westenberg @Daojoan@mastodon.social My 9 year old and his classmates have started using “that’s AI” to mean “I don’t believe you.” Me: we’re having dinosaur meat for dinner Kiddo: that’s AI Sep 24, 2025, 07:36 AM
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Reposted by Jesse Shapiro
jeremyjbarr.bsky.social
Jeremy Barr @jeremyjbarr.bsky.social · 14d
Excited to annouce the latest research published by our lab, which is led by Dinesh Subedi and is out today in Nature Microbiology.

www.nature.com/articles/s41...
Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections - Nature Microbiology
The Entelli-02 phage product containing five phages has frontline potential to address infections caused by the multidrug-resistant Enterobacter cloacae complex.
www.nature.com
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