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Caroline Menard

@caromenard666.bsky.social

2.6K followers 400 following 230 posts

🇨🇦 Associate Professor 👩‍🔬, Research Chair on Neurobiology of Stress & Resilience, foodie, gamer & metalhead. Menard Lab is @CERVO_ULaval @universitelaval in Quebec City 🧠🐭🔬🧪

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Caroline Menard @caromenard666.bsky.social · Feb 27

So excited to share the work of the fantastic Katarzyna, 1st 🧪PhD student of my lab 🧠, out in @natureneuro.bsky.social 🥂🥳
Cheers to the team, thanks to our precious collaborators and support from @braincanada.bsky.social #CIHR @fondsrechercheqc.bsky.social #newPI

www.nature.com/articles/s41...

Astrocytic cannabinoid receptor 1 promotes resilience by dampening stress-induced blood–brain barrier alterations - Nature Neuroscience

The mechanisms of neurovascular adaptations underlying stress resilience remain unclear. Here the authors show that the astrocytic endocannabinoid system modulates the blood–brain barrier changes duri...

www.nature.com

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Caroline Menard @caromenard666.bsky.social · 2d

It's that time of the year in Quebec City #Fall #color 🤩🌈🍁

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Caroline Menard @caromenard666.bsky.social · 6d

Yeeeessss congratulations Beth! 🥂

Caroline Menard @caromenard666.bsky.social · 6d

Congratulations Anastassia well deserved 🥂🎉

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Caroline Menard @caromenard666.bsky.social · 7d

Congratulations Ciaran well deserved! 🥂🎉

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Caroline Menard @caromenard666.bsky.social · 8d

Already shared in the lab Slack 🤓

Caroline Menard @caromenard666.bsky.social · 8d

Congratulations! 🥂🧠🇨🇦

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Reposted by Caroline Menard

Zach Pennington @zachtpennington.bsky.social · 9d

I’m hiring at all levels and accepting graduate students through Psychology and the Graduate Program in Neuroscience. Reach out if you’re interested in joining a collaborative, fun, creative, and supportive team in beautiful Vancouver! 🏔️ ⛷️ 🏖️ 🌆

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Reposted by Caroline Menard

Gergo Porkolab @gergoporkolab.bsky.social · 26d

Happy to share our new preprint on BBB mechanobiology on bioRxiv:
www.biorxiv.org/cgi/content/...

We describe an exciting new link between tight junctions and cell-matrix adhesions during BBB maturation and in epileptic BBB dysfunction.

Endothelial tight junctions and cell-matrix adhesions reciprocally control blood-brain barrier integrity

Brain endothelial cells (ECs) rely on mechanical cues to provide a physical barrier that protects the brain. Yet how ECs integrate forces to establish and maintain the blood-brain barrier (BBB) remain...

www.biorxiv.org

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Caroline Menard @caromenard666.bsky.social · 26d

Got the chance to chat with Michel "Away" Langevin, 🥁 drummer of the legendary metal band Voivoid 🤘 last night while waiting for our poutines! 🤩

Caroline Menard @caromenard666.bsky.social · 27d

Hot 🌶️ peppers experiment: all from our garden, jalapenos, Hungarian wax, shishitos of various colors..
Is the color associated with heat level 🔥?

Reposted by Caroline Menard

Brokoslaw Laschowski @drlaschowski.bsky.social · Sep 5

Come join us at University of Toronto. We're hiring a Professor of computational cognitive neuroscience.

#neuroAI #compneuro jobs.utoronto.ca/job/Toronto-...

Professor - Computational Cognitive Neuroscience

jobs.utoronto.ca

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Reposted by Caroline Menard

Mathieu Ferron @mathieuferron.bsky.social · 28d

Mood after the CIHR grant marathon.

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Reposted by Caroline Menard

Pallavi Banerjee @pallavib.bsky.social · 28d

JOB ALERT FOR #SOCIOLOGIST: Come work with me. We have FOUR Assistant Professor positions in the Sociology Department at the University of Calgary.

careers.ucalgary.ca/jobs/1672106...

Assistant Professors - Sociology, Faculty of Arts in Calgary, AB, ...

careers.ucalgary.ca

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Caroline Menard @caromenard666.bsky.social · Sep 4

🤩🤩🤩

Reposted by Caroline Menard

Daniel Durocher @durocher1.bsky.social · Aug 28

JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada at @sinaihealth.bsky.social. We provide a generous startup, fully funded salary and academic appointment at U of Toronto.

www.nature.com/naturecareer...

Please repost!

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Reposted by Caroline Menard

Ciarán Murphy-Royal @murphyroyallab.org · Aug 21

🚨Another PI job opening in the Neuroscience dept. at @umontreal.ca ! 🚨

www.nature.com/naturecareer...

Professor at the rank of Assistant or Associate Professor, in the field of neurocircuitry - Montréal, Quebec (CA) job with Université de Montréal | 12843808

Professor at the rank of Assistant or Associate Professor, in the field of neurocircuitry involved in the production of complex behaviors

www.nature.com

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Reposted by Caroline Menard

Andrew Iwaniuk @evoneuro.bsky.social · Aug 20

For anyone interested in an academic job in 🇨🇦, we will soon be advertising an Assistant Prof position in Systems Neuroscience (rodents and other animal models) at ULethbridge. There are many pros and cons of working here, so feel free to DM me to find out more
#neuroskyence #academicsky

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Caroline Menard @caromenard666.bsky.social · Aug 20

Congratulations! 🤓

Reposted by Caroline Menard

Carmen Sandi @carmensandi10.bsky.social · Aug 20

Happy to announce our new paper in Nature Communications: rdcu.be/eBpGY
We show how CRH in the thalamic reticular nucleus modulates NREM sleep, helping to understand how stress impacts sleep

Congrats to Loredana Cumpana and team, in work led by Simone Astori!
@epfl-brainmind.bsky.social‬

Corticotropin-releasing hormone modulates NREM sleep consolidation through the thalamic reticular nucleus

Nature Communications - Corticotropin-releasing hormone (CRH), known for activating the HPA axis during stress, also acts centrally in the brain. Here, the authors show that CRH modulates thalamic...

rdcu.be

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Caroline Menard @caromenard666.bsky.social · Aug 20

Fantastic work congratulations 🤓👏

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Reposted by Caroline Menard

Masha Prager-Khoutorsky @mashapk.bsky.social · Aug 19

Thrilled to share our new study showing microglia prune astrocyte processes in adult brain, to regulate synaptic transmission, hypothalamic neuron activity, and salt-induced hypertension in🐀. Huge team effort - congratulations to all🥂🍾🎉

Neuron @cp-neuron.bsky.social · Aug 19

Online now:

Microglia regulate neuronal activity via structural remodeling of astrocytes

Gu et al. showed that in rats fed a high-salt diet, reactive microglia accumulate around vasopressin-secreting neurons, phagocytosing astrocytic elements and pruning astrocytes. This causes glutamate spillover, increased neuronal activity, and excessive vasopressin release, contributing to salt-induced hypertension. The study reveals a novel mechanism by which microglia regulate synaptic transmission and neuronal activity through structural remodeling of astrocytes in the adult brain.

dlvr.it

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Reposted by Caroline Menard

Jonathan VanRyzin @jwvanryzin.bsky.social · Aug 13

I am SO EXCITED to share this one! The latest paper from the lab is online in @cp-cellreports.bsky.social. We show microglia prune NAc astrocyte processes during abstinence from cocaine-self ad which drives later drug seeking behavior.

www.sciencedirect.com/science/arti...

Abstinence from cocaine self-administration promotes microglial pruning of astrocytes, which drives cocaine-seeking behavior

Rodent drug self-administration leads to a compromised ability of nucleus accumbens astrocytes to maintain glutamate homeostasis as well as to reducti…

www.sciencedirect.com

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Reposted by Caroline Menard

Ciarán Murphy-Royal @murphyroyallab.org · Aug 8

Excellent paper from @emreyaksi.bsky.social @manumameli.bsky.social labs. So much gold in the supplementary figures!

www.nature.com/articles/s42...

Calcium dynamics in habenular astrocytes regulate active coping within behavioral transitions - Communications Biology

Tracking of astrocytes dynamics in habenula reveals their contribution to behavioral transitions across species.

www.nature.com

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Reposted by Caroline Menard

Dr. Cate Peña @cate-cholamine.bsky.social · Aug 6

Review now out in @npp-journal.bsky.social!
Epigenetic regulation of brain development, plasticity, and response to early life stress
rdcu.be/ezzYq

Epigenetic regulation of brain development, plasticity, and response to early-life stress

Neuropsychopharmacology - Epigenetic regulation of brain development, plasticity, and response to early-life stress

rdcu.be

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Reposted by Caroline Menard

María R. Aburto @maburto.bsky.social · Aug 6

So happy to see this excellent work out!

‘Gut microbiota regulates exercise-induced hormetic modulation of cognitive function’

Fantastic collaboration with @jltrejoneuro.bsky.social @cintadoelisa.bsky.social @jfcryan.bsky.social

www.thelancet.com/journals/ebi...

Gut microbiota regulates exercise-induced hormetic modulation of cognitive function

These findings suggest that the hormetic effects of physical exercise on cognitive function and neurogenesis are mediated by corresponding changes in the gut microbiota, highlighting a novel mechanist...

www.thelancet.com

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