Clement Pellegrin
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clempellegrin.bsky.social
Clement Pellegrin
@clempellegrin.bsky.social
European Commission 🇪🇺 - Joint Research Centre
Science | Food Fraud 🌶️| Plant-Microbe Interactions 🌲🌱🍄🪱 | Ethics
Views expressed are my own, not my employer's
Pinned
Go SUGR-1 >> The SUbventral-Gland Regulator (SUGR-1) of nematode virulence | Funded by the EU 🇪🇺 | Kudos to all authors 💪
The SUbventral-Gland Regulator (SUGR-1) of nematode virulence | PNAS
Pathogens must precisely tailor their gene expression to cause infection. However, a signaling cascade from host signal to effector production has ...
www.pnas.org
Reposted by Clement Pellegrin
"50 years after Hannah Arendt's death, the ideologies are back. On a global scale, but also in the everyday life of each individual. The globe is being redistributed, and it's not entirely clear how it will turn out. Arendt can teach us how to confront this world."

www.spiegel.de/internationa...
Never Out of Date: How Hannah Arendt Helps Us Understand Our World
Fifty years after her death in New York, Hannah Arendt has become the most popular philosopher of our time. For good reason: Her views are just as timely as ever.
www.spiegel.de
January 7, 2026 at 12:20 AM
Lost and found: Rediscovering microbiome-associated phenotypes that reshape agricultural sustainability | Science Advances www.science.org/doi/full/10....
Lost and found: Rediscovering microbiome-associated phenotypes that reshape agricultural sustainability
Rewilding corn with ancestral traits helps crops shape soil microbiomes, reduce fertilizer use, and supports sustainable farming.
www.science.org
January 5, 2026 at 7:42 AM
Reposted by Clement Pellegrin
Putin is banking on our failure to act.
We cannot afford to do him that favour.

The Reparations Loan is the most clear-cut option for sustained funding for Ukraine.

My doorstep ahead of today’s #EUCO
December 18, 2025 at 10:03 AM
Causes and consequences of experimental variation in Nicotiana benthamiana transient expression
Sophia N. Tang et al. doi: doi.org/10.1101/2025...
Causes and consequences of experimental variation in Nicotiana benthamiana transient expression
Infiltration of Agrobacterium tumefaciens into Nicotiana benthamiana has become a foundational technique in plant biology, enabling efficient delivery of transgenes in planta with technical ease, robu...
doi.org
December 3, 2025 at 4:04 PM
Reposted by Clement Pellegrin
🚨 Researchers have just found the presence of sugars, including ribose, lyxose, and glycose, on samples of Asteroid Bennu, which now has all of the ingredients for life as it exists on Earth.
In 2020, NASA’s OSIRIS-REx spacecraft touched down on Bennu—a carbon-rich asteroid drifting hundreds of m...
December 2, 2025 at 5:58 PM
Reposted by Clement Pellegrin
Induced endosymbiosis between a fungus and bacterium reveals a shift from antagonism to commensalism
Induced endosymbiosis between a fungus and bacterium reveals a shift from antagonism to commensalism
Endosymbioses represent dynamic relationships between organisms that may involve antagonistic phases during their emergence. Here, we induced cell-in-cell interactions between the free-living bacterium Ralstonia pickettii and an endosymbiont-free strain of the fungus Rhizopus microsporus using fluidic force microscopy to investigate the early phase of endosymbiosis formation. Following the implantation of bacteria into the cytosol, the rapid proliferation of R. pickettii compromised host fitness, as evidenced by reduced fungal viability, and triggered immune responses characterized by upregulated expression of stress-related defense genes. Vertical transmission of bacteria across fungal generations enabled repeated rounds of selective passaging, ultimately resulting in transcriptional relaxation of the fungal defense response. High-throughput-imaging revealed that the propagated system accommodated higher bacterial loads within viable spores, with a corresponding reduction in fungal growth. The observed physiological changes and comparative fungal transcriptomic profiles indicated adaptive resilience and a shift from antagonism to commensalism. This transition was characterized by attenuated expression of genes involved in cell wall remodeling and reactive oxygen metabolism. Our experimental system provides insights into the early processes of endosymbiosis, supporting the hypothesis that facultative intracellular pathogens can serve as intermediates toward stable endosymbiotic relationships.
sco.lt
December 2, 2025 at 12:02 PM
Genome modeling and design across all domains of life with Evo 2
Garyk Brixi, et al. bioRxiv 2025.02.18.638918; doi: doi.org/10.1101/2025...
Genome modeling and design across all domains of life with Evo 2
All of life encodes information with DNA. While tools for sequencing, synthesis, and editing of genomic code have transformed biological research, intelligently composing new biological systems would ...
doi.org
December 1, 2025 at 7:02 PM
Reposted by Clement Pellegrin
80% of our food crops and wild flowering plants depend on pollination.

Yet one-third of bee, butterfly and hoverfly species is in decline.

Our new EU Pollinator Monitoring Scheme aims to help reverse this trend by 2030.

More info: link.europa.eu/Jb7pBQ
November 27, 2025 at 8:25 AM
Common mycorrhizal networks facilitate plant disease resistance by altering rhizosphere microbiome assembly: Cell Host & Microbe www.cell.com/cell-host-mi...
Common mycorrhizal networks facilitate plant disease resistance by altering rhizosphere microbiome assembly
Common mycorrhizal networks (CMNs) facilitate chemical communication between plants. Zhang et al. demonstrate the transfer of jasmonic acid via CMN from Botrytis cinerea-infected donor plants to healt...
www.cell.com
November 12, 2025 at 1:00 PM
Reposted by Clement Pellegrin
The #CopernicusEU Sentinel-1 mission welcomes a new member: Sentinel-1D, launched at 21:02 GMT/22:02 CET from Kourou on Ariane 6 #VA265.

www.esa.int/Applications...

@cnes.fr @euspa.bsky.social @ec.europa.eu @thalesaleniaspace.bsky.social @transport.esa.int
November 4, 2025 at 10:54 PM
Reposted by Clement Pellegrin
🚨 The detection of the pinewood #nematode in France🇫🇷 exposes the flaws of current management strategies, focused on delaying rather than creating actual solutions, like we highlighted in our latest paper: doi.org/10.1007/s106...

📰 News: www.ouest-france.fr/environnemen...
Multiple factors associated with forest decline in the context of control measures for the pinewood nematode - European Journal of Plant Pathology
Forest decline is a complex phenomenon; however, there is often a tendency to oversimplify by attributing it to a single cause, neglecting the interaction of multiple factors. Ever since the detection...
doi.org
November 4, 2025 at 3:48 PM
Reposted by Clement Pellegrin
🌲 New 'Behind the Paper' post: go.nature.com/4qdUiLb 🌲

🔍 Forest decline is rarely caused by a single factor, and our latest study reveals why adopting a holistic perspective is key to managing pine wilt disease effectively. 🪱

👉 doi.org/10.1007/s106...

#PineWiltDisease #PinewoodNematode
Multiple factors associated with forest decline in the context of control measures for the pinewood nematode
Forest decline is a complex process rarely attributable to a single cause. Nevertheless, when widespread tree mortality occurs, management responses often focus on one primary agent. Our recent study ...
go.nature.com
October 20, 2025 at 2:47 PM
Reposted by Clement Pellegrin
We present a versatile microfluidics platform that makes multiplexed super-resolution imaging more accessible, reproducible, and high-throughput.

👉 BioRxiv: www.biorxiv.org/content/10.1...

#SuperResolution #DNApaint #Microfluidics #SMLM #OpenScience #multiplexing
October 15, 2025 at 12:29 PM
Reposted by Clement Pellegrin
Le temps presse pour le dirigeant russe / Poutine est en train de perdre la guerre, alors préparez-vous à une escalade
Putin is losing the war, so prepare for escalation
The clock is ticking for Russia’s leader – and that means Europe faces an imminent danger
www.telegraph.co.uk
October 11, 2025 at 10:03 AM
Reposted by Clement Pellegrin
💚 Reason for hope - Regulation works:

@ylaleena.bsky.social Executive Director of the @eea.europa.eu, who had previously tested her blood with @eeb.org, showed a decline in PFAS levels, reflecting trends observed among the European population for restricted PFAS.
October 7, 2025 at 7:35 AM
Reposted by Clement Pellegrin
This is a good article and I completely agree with its argument for comprehensible research.
July 21, 2025 at 10:58 PM
Reposted by Clement Pellegrin
DipGNNome: Diploid de novo genome assembly with geometric deep learning and beam-search https://www.biorxiv.org/content/10.1101/2025.09.16.676474v1
September 18, 2025 at 11:34 PM
Reposted by Clement Pellegrin
Pleased to share our new article in Cell Host & Microbe, a collaboration with the group of Zhong Wei at NJAU

Common mycorrhizal networks facilitate plant disease resistance by altering rhizosphere microbiome assembly

Free share link: authors.elsevier.com/c/1lnTD6t8JE...
September 16, 2025 at 11:16 PM
Reposted by Clement Pellegrin
🗣️ #PublicConsultation | Δ8-tetrahydrocannabinol (Δ8-THC) in food

Only a few days left to provide feedback on our draft scientific opinion about the risks to human health from Δ8-THC in food.

⏰ Submit your input by 15 September 2025

europa.eu/!Q3xNVh

#EUHaveYourSay #EFSA
September 12, 2025 at 5:52 AM
Reposted by Clement Pellegrin
Creativity in #science, a much-overlooked skill, in a podcast with potential for inspiration. Looking forward to listening!
www.buzzsprout.com/1744020/epis...
August 15, 2025 at 4:36 PM
Reposted by Clement Pellegrin
I'm outraged by the missile and drone attack on Kyiv, killing men, women and children.

And damaging our EU diplomatic mission.

My thoughts go to our brave staff.

Russia's strikes on Kyiv will only strengthen Europe's unity and Ukraine's defiance ↓

europa.eu/!T4rH8V
August 28, 2025 at 9:53 AM