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Reposted by David W. Sanders!

Eric Topol @erictopol.bsky.social · 18h

Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation
www.science.org/doi/10.1126/...

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David W. Sanders! @davidwsanders.bsky.social · 1d

Aaron is coming in a couple months. Hope to hear—not in talk form—about your work. Let’s catch up soon! Hope you are enjoying the non-Texas weather.

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David W. Sanders! @davidwsanders.bsky.social · 1d

It is very familiar. I have dealt with this nonsense for 15 years. Please don’t sully the reputation of my Alma mater with bullshit. Thanks.

David W. Sanders! @davidwsanders.bsky.social · 1d

I’m glad I didn’t follow your faculty market proposal/chalk talk advice. I would have received more offers. And I might not be at UTSW. And this would suck. Oh. And my dp2 ordered my projects as you recommended for job pitch. Wash-out of good/bad advice I think. So. Don’t owe you anything.

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David W. Sanders! @davidwsanders.bsky.social · 1d

This is great. Glad you joined us yeehaws in the beautiful state of Texas! And glad we can enjoy this lucky moment in the sun together. —apologies for the informality. I know we haven’t met. But @boeynaemssteven.bsky.social vouches for you. That is all I need to know to call you a friend.

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Reposted by David W. Sanders!

Graham Erwin @grahamerwin.bsky.social · 1d

Proud to announce that we received the NIH Director's New Innovator Award to develop a new class of genome editing tools!

From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 1d

Dr. Graham Erwin @grahamerwin.bsky.social receives NIH New Innovator Award! www.bcm.edu/news/dr-grah... @bcmhouston.bsky.social @bcmgenetics.bsky.social #BCMCancerCenter

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David W. Sanders! @davidwsanders.bsky.social · 1d

My proposal, like most DP2s, was pie in the sky stuff that I thought we would disprove quickly. Yet, we have not. This is thanks to our incredible postdoc, Shefali Banerjee, who is moving toward mic drop/textbook territory. We are in replication and red team/blue team territory now. Stay tuned.

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Reposted by David W. Sanders!

Ishmail Abdus-Saboor @ishmailsaboor.bsky.social · 1d

I’m extremely honored to be a recipient of the NIH Director’s Pioneer Award!

Columbia University's Zuckerman Institute @zuckermanbrain.bsky.social · 1d

Congratulations to @ishmailsaboor.bsky.social on receiving the NIH Director’s Pioneer Award, celebrating “scientists with outstanding records of creativity.” His lab will explore how the sense of touch can help build relationships. 🫶🧠💡

See zuckermaninstitute.columbia.edu/zuckerman-in...

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David W. Sanders! @davidwsanders.bsky.social · 1d

Don’t trigger me with your gen z jiffys on my big embargoed press release day. Cmon man.

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David W. Sanders! @davidwsanders.bsky.social · 1d

Fantastic. I will take this as inspiration for my lab to prove you wrong in the court of scientific opinion. Enjoy.

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David W. Sanders! @davidwsanders.bsky.social · 1d

As an expert on tau aggregation and stress granules…someone who has tried but failed to reproduce key findings with rigor and lack of bias…I am providing constructive discussion. Happy to eat crow if you provide a strong argument. It would certainly help me with funding.

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David W. Sanders! @davidwsanders.bsky.social · 1d

Sure. Not all science is reproducible. This is hype science. Buzzwords combined. No mechanism. Sound and fury, no meaning.

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David W. Sanders! @davidwsanders.bsky.social · 1d

When did stress granules become associated with tau aggregation? 🧐

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David W. Sanders! @davidwsanders.bsky.social · 1d

Humbled to announce that we received a New Innovator award. I thank the NIH’s civil servants for their hard work during a stressful funding cycle. I thank the leadership (and chair, Marc Diamond) at UTSW for betting on my lab’s high risk, high reward research. www.utsouthwestern.edu/newsroom/art...

UT Southwestern researcher receives NIH Director’s New Innovator Award

David Sanders, Ph.D., Assistant Professor in the Center for Alzheimer’s and Neurodegenerative Diseases and Molecular Biology at UT Southwestern Medical Center, has been awarded $2.4 million over five ...

www.utsouthwestern.edu

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Reposted by David W. Sanders!

From the Labs at Baylor College of Medicine @bcmfromthelabs.bsky.social · 1d

Dr. Graham Erwin @grahamerwin.bsky.social receives NIH New Innovator Award! www.bcm.edu/news/dr-grah... @bcmhouston.bsky.social @bcmgenetics.bsky.social #BCMCancerCenter

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Reposted by David W. Sanders!

Reto Fiolka @retof.bsky.social · 3d

We present multi-immersion Oblique Plane microscope (miOPM), a light-sheet platform that can be adapted to a wide range of applications, from sensitive live cell imaging to imaging organs and cleared tissues.
www.biorxiv.org/content/10.1...

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David W. Sanders! @davidwsanders.bsky.social · 10d

deserved. not only for your lab's contributions to hologram-incorporated stairwell photos. but also for yeoman's work in toiling with the boundaries of acronym development. I applaud the powerful washu provosts for their wise business acumen decisions!

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David W. Sanders! @davidwsanders.bsky.social · 10d

very cool. didn't know that poor facsimiles of myoblasts are prone to differentiating into poor facsimiles of neurons! such major scientific discoveries always require standing on the shoulders of giants, even if it means taking inspiration from their blots/microscopy images.

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Reposted by David W. Sanders!

Alex Holehouse @alexholehouse.bsky.social · 11d

Last week, Washington University made the perhaps questionable decision to award me tenure.

Lab picture of Holehouse lab members past and present

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Reposted by David W. Sanders!

boehninglab @boehninglab.com · 15d

A single brain infusion of miRNA targeting CAG repeats slows the progression of Huntington's disease by 75% in patients. This is something that I never thought I would see in my lifetime. www.uniqure.com/investors-me...

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Reposted by David W. Sanders!

John Ngo @johntngo.bsky.social · 17d

🚀 Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/

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Reposted by David W. Sanders!

brangwynnelab.bsky.social @brangwynnelab.bsky.social · 19d

A tremendous honor! Thrilled & humbled to receive 2025 Keio Medical Science Prize for launching LLPS #phaseseparation field (= #softmatter + #cellbio) w collaborators esp @HymanLab. & Congrats to Akiko Iwasaki @virusesimmunity.bsky.social. www.princeton.edu/news/2025/09...
#KeioMedicalSciencePrize

Bioengineer Clifford Brangwynne wins Keio Medical Science Prize

Japan’s Keio University awards the prize annually to honor contributions in medicine and life sciences. Brangwynne is being recognized for groundbreaking work that has opened up a new field of cell bi...

www.princeton.edu

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Reposted by David W. Sanders!

brangwynnelab.bsky.social @brangwynnelab.bsky.social · 20d

these people in my lab are amazing

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Reposted by David W. Sanders!

HHMI @hhmi.org · 21d

🎉 Congratulations to HHMI Investigators Clifford Brangwynne and Akiko Iwasaki, the two winners of the 30th annual Keio Medical Science Prize. This international prize, awarded by Keio University in Tokyo, honors scientists who have made major contributions to the fields of medical or life sciences.

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David W. Sanders! @davidwsanders.bsky.social · 21d

That being said, chuffing is STILL out. Soooo 2020.

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