Lightnews — Scholar-powered news

Reposted by dennis hernaus

Andrew Reid @reid-lab.org · 14d

This one looks intriguing. Arousal "embedding" whole-brain dynamics. 🤯

#neuroskyence #compneurosky

doi.org/10.1038/s415...

Arousal as a universal embedding for spatiotemporal brain dynamics - Nature

Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.

doi.org

4 16 48

Reposted by dennis hernaus

MwahahahahahadScientist @mads100tist.bsky.social · 22d

'Memento', but it's every plot you make in R

4 4 22

Reposted by dennis hernaus

Phil Corlett @philcorlett.bsky.social · 22d

somehow I missed this!

Dopamine represents a domain-general teaching signal:

www.science.org/doi/full/10....

Striatal dopamine signals errors in prediction across different informational domains

Dopamine reflects prediction errors not only about reward but also about valueless stimuli, challenging many current theories.

www.science.org

2 9 25

Reposted by dennis hernaus

Michael W. Cole @mwcole.bsky.social · 24d

Lab’s latest is out in Imaging Neuroscience, led by Kirsten Peterson: “Regularized partial correlation provides reliable functional connectivity estimates while correcting for widespread confounding”, where we demonstrate a major improvement to standard fMRI functional connectivity (correlation) 1/n

5 30 74

Reposted by dennis hernaus

Nils Kroemer @nbkroemer.bsky.social · Aug 30

New preprint...and this one is truly EPIC 🚨.

Using a large group of patients with depression and healthy controls (N>800), we show differences in the functional segregation of insular subnetworks. And we can use it to classify!
Led by @glassybrain.bsky.social #neuroskyence 🩺
osf.io/preprints/ps...

Graphical summary of the analysis pipeline

Decreased similarity within the anterior insula cortex drives group differences between patients with MDD and healthy control participants. This difference is illustrated by shift functions and compared to control regions in the temporal cortex.

Patients with depression can be robustly classified based on functional connectivity profiles, and the accuracy improves with increasing symptom severity.

4 27 93

Reposted by dennis hernaus

Eric Topol @erictopol.bsky.social · 28d

Discovery of a brain center (BNST) that controls consumption (including sweets, fats, salt and other foods) in mice
www.cell.com/cell/fulltex...

A brain center that controls consummatory responses

The BNST brain region integrates a broad range of external and internal signals to flexibly regulate consumption, revealing a unified control over consummatory responses.

www.cell.com

3 38 130

Reposted by dennis hernaus

Russ Poldrack @russpoldrack.org · 28d

This was a fun piece to write

SPM as a cornerstone of an open source software ecosystem for neuroimaging

Abstract. The SPM software package played a major role in the establishment of open source software practices within the field of neuroimaging. I outline i

track.smtpsendmail.com

2 4 27

dennis hernaus @dhernaus.bsky.social · 29d

We think these results highlight how cortisol stress reactivity is shaped by small distributed contributions across states, biology, and context.

No single psychological variable dominates in our sample. This raises questions re psychological interpretations of cortisol reactivity (caution!). (4/4)

1

dennis hernaus @dhernaus.bsky.social · 29d

Findings: 🔽 Positive affect during stress → very modest but consistent predictor of cortisol reactivity. 🔼 Negative affect → only linked to one cortisol metric, not robust. BIS/BAS traits → no association. (3/4)

1

dennis hernaus @dhernaus.bsky.social · 29d

We used the Maastricht Acute Stress Test to assess cortisol reactivity (peak, turnover, responder status) and measured affect (PANAS), traits (BIS/BAS) and biological & contextual covariates

Then we used LASSO regression to find the most robust predictors of cortisol stress reactivity. 🤠 (2/4)

1

dennis hernaus @dhernaus.bsky.social · 29d

In our new paper 📖🔥, we conducted a pooled analysis (n=443; 5 studies) to test if state affect (momentary mood) or trait dispositions (approach/avoidance) predict cortisol reactivity beyond biological & contextual factors. (1/4)

#neuroscience #Neuroskyence #cogpsyc #AffectSci #psychscisky

Unpacking cortisol stress reactivity: Associations with psychological state and trait data in a pooled data sample

Prior research suggests that cortisol responses to acute stress induction paradigms (i.e., “cortisol stress reactivity”) likely arise from complex int…

www.sciencedirect.com

1 5 19

Reposted by dennis hernaus

Alex Pike @alexandrapike.bsky.social · Sep 4

Hello hivemind! I haven't seen one of these in a while but I know that back-in-the-day they were all the rage: does anyone have a funky spreadsheet of MH/psych/neuro-relevant grants/fellowships for ECRs that they wouldn't mind me sharing with my lab?

a donkey is standing on a dirt field and asking for something .

ALT: a donkey is standing on a dirt field and asking for something .

media.tenor.com

4 2

Reposted by dennis hernaus

FrankLab_LNCC @lnccbrown.bsky.social · Sep 4

check out Jake Russin's new paper on how the interplay between in-context and in-weight learning in neural nets can explain tradeoffs in human learning!
pnas.org/doi/epdf/10....

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

pnas.org

4 6

dennis hernaus @dhernaus.bsky.social · Sep 1

Looks like a great show. Saw them in Manchester. Truly biblical.

2

Reposted by dennis hernaus

Anne Urai 🟥 @anne-urai.bsky.social · Jul 4

My latest: a short review on latent variable models to help uncover trial-to-trial structure in perceptual decision-making strategies

authors.elsevier.com/a/1lMiv4sIRv...

2 22 60

Reposted by dennis hernaus

Matthew Apps @brainapps.bsky.social · Jul 4

I am delighted to announce registration and abstract submission is open for "The Mechanistic Basis of Foraging 2025" to be held at the Edgbaston Park Hotel, University of Birmingham, UK on 3-5th November 2025. uobevents.eventsair.com/the-mechanis...

Homepage - The Mechanistic Basis of Foraging

uobevents.eventsair.com

1 17 25

Reposted by dennis hernaus

Damien Fair @drdamienfair.bsky.social · Jun 26

Alert!!!!

“An Action Networks Model for Pain”

We propose a new model for chronic pain — and highlight two functionally connected cortical networks that could revolutionize how we treat it.

👉 thread below 🧵

osf.io/preprints/ps...

2 42 91

Reposted by dennis hernaus

Nils Kroemer @nbkroemer.bsky.social · Jun 21

Our big behavioral precision mapping preprint is out. Based on 1,486,950 observed choices in a reward learning task, we show that BMI is associated with higher and more variable learning rates. Binge eating was associated with lower reward sensitivity. #neuroskyence 🩺
www.medrxiv.org/content/10.1...

To determine distinct learning and decision-making profiles in obesity and binge eating (BE), we combined ecological momentary assessment (EMA) in a large online sample with a neuroimaging study. The figure shows the elements of the paper.

Binge eating (BE) is associated with reduced but more variable reward sensitivity. The panels show associations of BE with learning parameters and an fMRI-based reward sensitivity measure derived from the cue stage of an effort task (independent of learning).

2 20 55

Reposted by dennis hernaus

Nature Methods @natmethods.nature.com · Jun 6

An Analysis of 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure-function coupling and behavior prediction highlights their effectiveness for neurophysiological applications.

www.nature.com/articles/s41...

Benchmarking methods for mapping functional connectivity in the brain - Nature Methods

In this Analysis, Liu et al. benchmark more than 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure–function coupling and behavio...

www.nature.com

31 51

Reposted by dennis hernaus

Lucina Uddin @lucinauddin.bsky.social · May 28

When I first started working with resting state fMRI as a postdoc, there was a lot of skepticism about what we could learn from it. 20 years later, it's hard to imagine where the field of neuroscience would be without it. Here's a summary 🧠 www.nature.com/articles/s41...

The history and future of resting-state functional magnetic resonance imaging - Nature

This Review provides an overview of the history of resting-state functional MRI research, which has helped to reveal the spatiotemporal organization of the brain, and discusses how it can contribute f...

www.nature.com

1 77 160

dennis hernaus @dhernaus.bsky.social · May 28

Still open for expressions of interest until June 15th! Do reach out directly (or see link) if you're interested in developing an MSCA-Postdoc. Fellowship application on the (cognitive) neuroscience of motivation/goal-directed behaviour 🧠

👇

#cognitiveneuroscience #Neuroscience
#postdoc #cogsci

MSCA-PF in Cognitive Neuroscience with Dr Dennis Hernaus

euraxess.ec.europa.eu

1 1

Reposted by dennis hernaus

PsyArXivBot @psyarxivbot.bsky.social · Apr 17

A Reinforcement Learning and Decision-Making framework for understanding Mental Disorders: https://osf.io/s58jh

1 2

Reposted by dennis hernaus

Vanessa Teckentrup @glassybrain.bsky.social · Apr 4

Transcutaneous auricular vagus nerve stimulation (taVNS) and fMRI: a great combination to test the mechanism of action driving stimulation effects 🧠
But how to use the stimulation safely within the magnetic field? We looked into this! #neuroskyence
doi.org/10.31234/osf...

OSF

doi.org

1 5 17

Reposted by dennis hernaus

Emerson Harkin @efharkin.bsky.social · Mar 27

Serotonin neurons are known for their puzzling responses to rewards and punishments that don't quite fit with simple theories based on reward, punishment, surprise, salience, or uncertainty. Theories of serotonergic function seem to be diverging over time.

efharkin.com/blog/2024-07...

3/6

A partial history of the serotonin literature

efharkin.com

4 2 9

Reposted by dennis hernaus

Phil Corlett @philcorlett.bsky.social · Mar 26

Out today in American Journal of Psychiatry: psychiatryonline.org/doi/10.1176/...
@kurtfraser.bsky.social and I evaluate the Aberrant Salience hypothesis of psychosis in light of the work it inspired over the last 20 years. We still find it ambitious and beautiful, but the devil is in the details

20 Years of Aberrant Salience in Psychosis: What Have We Learned? | American Journal of Psychiatry

Twenty years ago Shitij Kapur’s “Psychosis as a state of aberrant salience” captured the attention of clinicians and cognitive and behavioral neuroscientists. It has become the de facto way of talking...

psychiatryonline.org

4 32 56