Lightnews — Scholar-powered news

Doryen Bubeck @doryenbubeck.bsky.social · 7d

Thanks @ccpem.bsky.social for an excellent workshop today showing @imperiallifesci.bsky.social what we can do with #doppio on our new computing cluster funded by @ukri.org

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Reposted by Doryen Bubeck

Juha Huiskonen @juhahuiskonen.bsky.social · Jul 8

In our latest preprint on bioRxiv, we present the in situ structure of
the human gap junction at 14 Å resolution using cryo-ET.

The structure provides a blueprint for investigating how connexin
regulation shapes intercellular communication in health and disease.

CryoET tomogram with the gap junction (green), ribosomes (cyan) and microtubules (pink)

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Reposted by Doryen Bubeck

Matt Higgins @parasitematt.bsky.social · Jun 13

Our latest story describes the amazing evolutionary battle between malaria parasite and human. The parasite evolved RIFINs to bind inhibitory KIR receptors and suppress immune cell function while humans have activating KIR receptors to bind these RIFINs to kill parasites!

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Reposted by Doryen Bubeck

Imperial Life Sciences @imperiallifesci.bsky.social · Jun 8

Thank you everyone who sponsored the @doryenbubeck.bsky.social Bubeck lab to run the CRUK Pretty Muddy Race for Life. The team raised over £1200!

#OurImperial

fundraise.cancerresearchuk.org/page/doryens...

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Reposted by Doryen Bubeck

CRUK Convergence Science Centre @crukconvergence.bsky.social · Jun 2

Join us for our next #ConvergingOnCancer seminar where we'll explore these topics with:

➡️Prof @doryenbubeck.bsky.social‬ (@imperialsci.bsky.social‬)
➡️Dr @claudioalfieri.bsky.social‬ (@icr.ac.uk‬ )

📅 Thursday 5th June, 3-4pm
🖱️ For more information and how to register: bit.ly/3Z80SqS

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Reposted by Doryen Bubeck

Kat Toropova @kattoropova.bsky.social · May 28

⏰ Deadline approaching for postdoc position in my lab, Dunn School, University of Oxford.

We work on how the cell's antenna receives and transmits essential signals through motor protein driven transport.

❄️ Cryo-EM/ET, smTIRF, cell biology methods 🧪🔬

30/5/25 ➡️ tinyurl.com/KToropovaPDRA

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Reposted by Doryen Bubeck

Imperial Life Sciences @imperiallifesci.bsky.social · May 24

Still time to sponsor @doryenbubeck.bsky.social who ran the Pretty Muddy Race for Life for Cancer Research UK this weekend! Congrats Doryen!

fundraise.cancerresearchuk.org/page/doryens...

Doryen's Race for Life

I haven't met a single person whose life has not been touch by cancer. The current statistic is that 1 in 2 people will be diagnosed with cancer in their lifetime. As a scientist I know the significan...

fundraise.cancerresearchuk.org

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Reposted by Doryen Bubeck

Imperial Life Sciences @imperiallifesci.bsky.social · May 15

Exciting progress in drug discovery - a cross-disciplinary team including @doryenbubeck.bsky.social, Tate and Kawamura researchers have developed the first macrocyclic peptide inhibitors for CD59 — a tricky cell-surface receptor often hijacked by bacteria.

www.imperial.ac.uk/news/263433/...

Macrocyclic peptide inhibitors for CD59 receptor | Imperial News | Imperial College London

A collaboration between the Tate, Bubeck and Kawamura groups has developed the first macrocyclic peptide inhibitors for cell-surface receptor CD59

www.imperial.ac.uk

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Reposted by Doryen Bubeck

Kelly Nguyen @kellythd-nguyen.bsky.social · Apr 16

We are looking for a postdoctoral fellow to join us to explore telomerase regulation by histones. Please get in touch if this may interest you.

MRC Laboratory of Molecular Biology @mrclmb.bsky.social · Apr 16

Excellent opportunity available for a motivated #postdoc to join @kellythd-nguyen.bsky.social’s group investigating the roles of histones in regulating telomerase using a multi-disciplinary approach.
More details: www.nature.com/naturecareer...
Apply by 04 MAY
#PostdocJobs #ScienceJobs

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Doryen Bubeck @doryenbubeck.bsky.social · Apr 14

Great day collecting cryo SIM data @diamondlightsource.bsky.social

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Doryen Bubeck @doryenbubeck.bsky.social · Apr 13

Thanks Nick! Looking forward to visiting TSL in May.

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Doryen Bubeck @doryenbubeck.bsky.social · Apr 8

Honored to have been chosen for this year’s GlaxoSmithKline Award from @biochemsoc.bsky.social. A big thank you to lab members past and present @imperialsci.bsky.social and @erc.europa.eu @cruk-si.bsky.social @wellcometrust.bsky.social for supporting our work.

Biochemical Society @biochemsoc.bsky.social · Apr 8

The 2026 GlaxoSmithKline Award goes to Doryen Bubeck! Internationally recognised, @doryenbubeck.bsky.social's pioneering research in structural immunology has laid a foundation for future treatments targeting immune-mediated diseases and infectious pathogens.

The Biochemical Society 2026 Awards
The GlaxoSmithKline Award
Professor Doryen Bubeck
Imperial College London, UK

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Reposted by Doryen Bubeck

Imperial Life Sciences @imperiallifesci.bsky.social · Mar 19

Did you miss the @doryenbubeck.bsky.social inaugural lecture last week or just fancy re-watching?! 😀

Join Doryen in the fascinating world of proteins, the "tiny machines" that drive cellular functions, using cryo electron microscopy.

www.youtube.com/live/H14PeFt...

#OurImperial

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Reposted by Doryen Bubeck

Imperial Life Sciences @imperiallifesci.bsky.social · Mar 17

We're excited that Facilities Manager Sam Horrell has made it to the London Final of FameLab, a science outreach competition with 3 minutes to explain a scientific topic in an engaging way. The final is on 2 April and is free - please come & support Sam!

www.eventbrite.co.uk/e/london-fam...

London FameLab Final

Experience the excitement of the London FameLab Final! Enjoy engaging science talks as contestants compete for a place in the UK Final.

www.eventbrite.co.uk

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Doryen Bubeck @doryenbubeck.bsky.social · Mar 15

www.youtube.com/watch?v=H14P...

Big questions, tiny machines

YouTube video by Imperial College London

www.youtube.com

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Reposted by Doryen Bubeck

Alexey Amunts @amunts.bsky.social · Mar 12

Sad news about Karen Davies' passing.
Karen was an inspiration in bioenergetics and cryoET. Her pioneering postdoctoral work on ATP synthase and respiratory supercomplexes marked turning points in the field. I created Scholar profile to acknowledge her contribution
scholar.google.com/citations?hl...

Karen Davies

‪Formerly of Electron Bio-Imaging Centre, Diamond Light Source, United Kingdom‬ - ‪‪Cited by 2,887‬‬ - ‪cryo-EM‬ - ‪tomography‬ - ‪method development‬ - ‪bioenergetics‬

scholar.google.com

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Doryen Bubeck @doryenbubeck.bsky.social · Mar 13

Thank you so much! The demo was so much fun to do ☄️☄️☄️

Reposted by Doryen Bubeck

Stephen Graham's Lab @atomicvirology.bsky.social · Mar 12

Great live demonstration of how election microscopy works, and the signal to noise challenge in atomic imaging, at @doryenbubeck.bsky.social's inaugural lecture #imperialinaugural

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Reposted by Doryen Bubeck

Imperial Life Sciences @imperiallifesci.bsky.social · Mar 12

Amazing inaugural lecture tonight from @doryenbubeck.bsky.social

Proteins scatter electrons, but the images are noisy...check out how an electron microscope works as showcased by our Head of Department @dandavis101.bsky.social 😄😃🔬

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Reposted by Doryen Bubeck

Imperial Life Sciences @imperiallifesci.bsky.social · Mar 12

Thanks so much @doryenbubeck.bsky.social for an amazing inaugural lecture tonight, 'Big Questions, Tiny Machines' nothing short of inspiring for our packed audience! 👩‍🏫

#OurImperial

Did you miss it?! No worries if so, as you can check out the recording below:

www.youtube.com/live/H14PeFt...

Big questions, tiny machines

YouTube video by Imperial College London

www.youtube.com

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Reposted by Doryen Bubeck

Stephen Curry @scurry.bsky.social · Mar 12

A highlight of Professor @doryenbubeck.bsky.social‘s inaugural lecture tonight was @dandavis101.bsky.social being pounded with electrons…

Dan, in white lab coat with a shield, sends of electrons being thrown at by an assembled mob of audience volunteers.

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Reposted by Doryen Bubeck

Astbury Biostructure Laboratory @astbury-bsl.bsky.social · Mar 11

🎉 And that’s a wrap!

The Wellcome-MRC Cryo-EM in Structural Biology 2025 course in Leeds was a fantastic week of learning, hands-on training, and great discussions.

Huge thanks to our amazing instructors, speakers & enthusiastic participants for making it such a success! #CryoEM

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Reposted by Doryen Bubeck

Imperial Life Sciences @imperiallifesci.bsky.social · Feb 17

Don't forget to come to Prof Doryen Bubeck's inaugural lecture, "Big Questions, Tiny Machines"! Open to all!!

📅 Wed, 12 March 2025

Understanding how pathogen proteins interact with human defence systems means we can develop new ways to prevent disease.

@doryenbubeck.bsky.social

#OurImperial

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Reposted by Doryen Bubeck

byrnelabicl.bsky.social @byrnelabicl.bsky.social · Feb 4

Really looking forward to this. Come along if you can!

Imperial Science @imperialsci.bsky.social · Feb 3

🔬 Join us for Prof Doryen Bubeck's inaugural lecture, "Big Questions, Tiny Machines"

@doryenbubeck.bsky.social @imperiallifesci.bsky.social

📅 Wed, 12 March 2025

Discover how structural biology has changed the game when studying proteins & their role in immune responses 👉 bit.ly/4aHdABe

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Reposted by Doryen Bubeck

Imperial Science @imperialsci.bsky.social · Feb 3

🔬 Join us for Prof Doryen Bubeck's inaugural lecture, "Big Questions, Tiny Machines"

@doryenbubeck.bsky.social @imperiallifesci.bsky.social

📅 Wed, 12 March 2025

Discover how structural biology has changed the game when studying proteins & their role in immune responses 👉 bit.ly/4aHdABe

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