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Reposted by Kelly Nguyen

Ryan Flynn @raflynn5.bsky.social · 2d

Lead by postdoc in the lab Ruiqi Ge and in collaboration with Bob Coffey’s lab, we are happy to share rPAL-seq for rapid and sensitive sequencing based profiling of glycoRNAs @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

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Reposted by Kelly Nguyen

Jacqueline Jacobs @jacqjacobs.bsky.social · 2d

Are you a postdoc looking for a new challenge and do you match the profile? Apply to join us! Especially, if you have experience with addressing the mechanisms underlying telomere maintenance, DNA replication or DNA repair. www.werkenbijavl.nl/vacatures/po...

Postdoc - Telomere and Genome Maintenance | Werken bij AVL

The research group of Jacqueline Jacobs at the division of Oncogenomics aims to identify new factors and molecular mechanisms that are critical in telomere and genome maintenance through appropriate D...

www.werkenbijavl.nl

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Reposted by Kelly Nguyen

Briggs Group @briggsgroup.bsky.social · 2d

The mechanistic basis of cargo selection during Golgi maturation. From Rebecca Taylor, @katciazynska.bsky.social, @jggkaufman.bsky.social & @grigorytagiltsev.bsky.social at @mpibiochem.bsky.social with David Owen and Sean Munro's group @cellbiol-mrclmb.bsky.social | www.science.org/doi/10.1126/...

The mechanistic basis of cargo selection during Golgi maturation

Resident proteins of the Golgi recycle in vesicles and the protein GOLPH3 enables the COPI vesicle coat to accomplish this.

www.science.org

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Reposted by Kelly Nguyen

Camille Moore @camille-moore.bsky.social · 6d

Today I am so pleased to present our work on how chromatin remodelers affect mesoscale chromatin organization.
www.science.org/doi/10.1126/...

ATP-dependent remodeling of chromatin condensates reveals distinct mesoscale outcomes

Adenosine triphosphate (ATP)–dependent chromatin remodeling enzymes mobilize nucleosomes, but how such mobilization affects chromatin condensation is unclear. We investigate effects of two major remod...

www.science.org

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Kelly Nguyen @kellythd-nguyen.bsky.social · 5d

Congratulations Camille!

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Reposted by Kelly Nguyen

Joe Peters Lab @joepeterslab.bsky.social · 5d

The Peters lab is looking for a new team member! The role transposons play in evolution, basic mechanisms regulating transposition, and applying transposons as tools for genome modification with a special focus on guide RNA-directed transposition. cornell.wd1.myworkdayjobs.com/CornellCaree...

Technician III - Department of Microbiology

Position Summary This position will be in the lab of Dr. Joseph E. Peters in the Department of Microbiology. Research in the Peters’ lab broadly involves deciphering mechanisms in genome stability and...

cornell.wd1.myworkdayjobs.com

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Reposted by Kelly Nguyen

(GIRISH)MALI LAB @dyneinassembly.bsky.social · 9d

Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia.

Open access link below:
www.nature.com/articles/s41...

Here's a cool animated summary

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Reposted by Kelly Nguyen

Samara Reck-Peterson @samreckpeterson.bsky.social · 9d

We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22.
biochem.weill.cornell.edu/join-our-fac...

Join our Faculty | Department of Biochemistry & Biophysics

Call for applications:We invite applications for a tenure-track Assistant Professor position in the newly established Department of Biochemistry and Biophysics. We are conducting an open search for ou...

biochem.weill.cornell.edu

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Kelly Nguyen @kellythd-nguyen.bsky.social · 9d

Congratulations @dyneinassembly.bsky.social! Great to see this in final form.

Nature Structural & Molecular Biology @natsmb.nature.com · 9d

New online: Molecular basis for the activation of outer dynein arms in cilia

Molecular basis for the activation of outer dynein arms in cilia

Nature Structural & Molecular Biology, Published online: 29 September 2025; doi:10.1038/s41594-025-01680-9Issa et al. show that the ciliary small guanosine triphosphatase Arl3 displaces the inhibitory regulator Shulin/DNAAF9 from the outer dynein arm, leading to motor activation.

go.nature.com

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Reposted by Kelly Nguyen

Lucas Farnung @lucas.farnunglab.com · 9d

New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com

Protein Domain Designer tool for the generation of publication-ready protein domain diagrams

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Reposted by Kelly Nguyen

Tina Perica @glukozica.bsky.social · 10d

First work on kinases from my lab! Working on this project, I often remembered the late Cyrus Chothia who said that if the data doesn’t fit a beautiful model, maybe it’s not the model, maybe you just need more data. :)

bioRxiv Biochemistry @biorxiv-biochem.bsky.social · 11d

Mechanism of MEK1 phosphorylation by the N-terminal acidic motif mediated asymmetric BRAF dimer https://www.biorxiv.org/content/10.1101/2025.09.26.678760v1

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Reposted by Kelly Nguyen

Lori Passmore @lapassmore.bsky.social · 11d

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM

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Reposted by Kelly Nguyen

MRC Laboratory of Molecular Biology @mrclmb.bsky.social · 20d

We’re looking for a #postdoc to join Lori Passmore’s group, within a programme aimed at understanding addition of mRNA poly(A) tails

More info: www.nature.com/naturecareer...
Closes 06 OCT
#ScienceJobs #PostdocJobs

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Reposted by Kelly Nguyen

Misha Kudryashev @mishakudryashev.bsky.social · 16d

We have a preprint of a book chapter for you: Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles.

We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography

zenodo.org/records/1717...

Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles

zenodo.org

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Reposted by Kelly Nguyen

Di Antonio Research Group @diantoniogroup.bsky.social · 20d

We are hiring! We are looking for a PDRA to study the epigenetics of breast cancer dormancy using chemical biology and genomics approaches. This is a 3-year position and is aimed at chemical biologists or biologists. Please share and apply using the link below 👇👇👇

www.imperial.ac.uk/jobs/search-...

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

www.imperial.ac.uk

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Reposted by Kelly Nguyen

Hopfner Lab @hopfnerlab.bsky.social · 20d

Thrilled that our work is now finally out in Nature Comms!
rdcu.be/eG3vP

We reveal cryo-EM structures of the MRN complex bound to DNA & TRF2 - showing how DNA breaks are sensed and regulated at telomeres.
Fantastic work by first authors @yilanfan.bsky.social @filizkuybu.bsky.social & Hengjun!

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Reposted by Kelly Nguyen

MRC Laboratory of Molecular Biology @mrclmb.bsky.social · 21d

🎉 Happy Postdoc Appreciation Week! 🎉
As LMB Group Leaders @kellythd-nguyen.bsky.social, @brfalcon.bsky.social & @marta-shahbazi.bsky.social attest, our postdocs are at the heart of our research community and shape everything we do.
Thank you postdocs!
#PostdocAppreciationWeek #PAW25

We are deeply grateful to the incredible postdocs in our labs, who’s creativity and dedication push the boundaries of research every day and who’s energy makes the LMB such a fun and inspiring place. The future of science is bright!
Kelly Nguyen
LMB Group Leader

Thank you to all the postdocs in our group, past and present. It is a privilege to work with such an excellent team of scientists.
Benjamin Ryskeldi-Falcon
LMB Group Leader

I am grateful to all the amazing postdocs in my lab. They are great scientists, colleagues, and mentors. Our research wouldn’t be possible without them!
Marta Shahbazi
LMB Group Leader

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Reposted by Kelly Nguyen

Stella Hurtley @smhsci.bsky.social · 22d

Re-upping this - applications will close - open to UK-based people too!!!

Stella Hurtley @smhsci.bsky.social · Aug 22

Come join us @science.org. We’re looking for a new editor to look after infectious disease and microbiome submissions.
Check out this Associate or Senior Editor opportunity recruiting.ultipro.com/AME1123ASEM/...

recruiting.ultipro.com

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Reposted by Kelly Nguyen

Oli Clarke @olibclarke.bsky.social · 26d

This one is a bit of a departure from the usual and definitely a work in progress!

We found that by using ab initio reconstruction at very high res, in very small steps, we could crack some small structures that had eluded us - e.g. 39kDa iPKAc (EMPIAR-10252), below.

Read on for details... 1/x

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Reposted by Kelly Nguyen

(GIRISH)MALI LAB @dyneinassembly.bsky.social · 29d

The annual Dunn School DPhil studentship competition for 2026 is open for applications.

We have a project aimed at understanding the molecular mechanisms of ciliary dynein transport. See details below and please pass on to anyone who might be interested.

www.path.ox.ac.uk/project/mech...

Mechanistic studies on axonemal dynein transport to motile cilia - Dunn School

Over 30 groups work at the Dunn School to uncover the molecular and cellular mechanisms underlying disease. Discover which research groups are accepting students for our next round of applications.

www.path.ox.ac.uk

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Reposted by Kelly Nguyen

Sandra Segura-Bayona @ssegurabayona.bsky.social · 27d

🚀 New preprint alert!

We uncover SLFN11 as a molecular gatekeeper that restricts alternative lengthening of telomeres (ALT) by sensing telomere-associated replication stress and triggering apoptosis.

📄 Read the manuscript here: www.biorxiv.org/content/10.1...

SLFN11 restricts escape from telomere crisis to prevent alternative lengthening of telomeres

The tRNA nuclease SLFN11 is epigenetically silenced in ~50% of treatment-naive tumours and is the strongest predictor of chemoresistance but why it is frequently inactivated in cancer is unknown. To a...

www.biorxiv.org

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Reposted by Kelly Nguyen

Marc Bühler @marcbuhler.bsky.social · Sep 8

We are hiring-join us!

FMI science @fmiscience.bsky.social · Sep 8

🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬
Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...

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Reposted by Kelly Nguyen

The EMBO Journal @embojournal.org · 29d

Resistance to CDK7 inhibitors directed by acquired mutation of a conserved residue in cancer cells
Laki Buluwela @simak.bsky.social @bjgreber.bsky.social et al find a single base change of #CDK7 conferring resistance to non-covalent CDK inhibition in prostate cancer
www.embopress.org/doi/full/10....

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Reposted by Kelly Nguyen

MRC Laboratory of Molecular Biology @mrclmb.bsky.social · Sep 4

Want to help inspire future generations of scientists? Are you passionate about #SciComm? We have a Public Engagement and Communications Officer (Maternity Cover) position in the LMB engagement & comms team:

www.reed.co.uk/jobs/public-...

Closes 21 SEP
#SciCommJobs

Images of children and young people taking part in Public Engagement activities

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Reposted by Kelly Nguyen

Rachael Kretsch @rachael-kretsch.bsky.social · Sep 2

We have restarted our global Nucleic Acid Strcuture webinar series to bring the expiremental and computational communities together to discuss new developments in the field. Join us this Thursday for the next webinar. Sign up to our mailing list here: groups.google.com/g/casp-rna-sig

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