Lightnews — Scholar-powered news

Reposted by Devin Schweppe

Pedro Beltrao @pedrobeltrao.bsky.social · 16h

Our group has a PhD position open in this Doctoral network. Our topic is around combining proteomics AI and protein structures. Look through the website below to look at all of the projects/groups and apply.

protaiomics.bsky.social @protaiomics.bsky.social · 16h

🌟Ready to apply?
16 fully funded PhD positions are open in ProtAIomics Doctoral Network!
Join 16 labs across Europe to advance AI-powered proteomics and drive discoveries in health & biotechnology.
👉 Apply here: www.protaiomics.eu
#Proteomics #ArtificialIntelligence #MSCA #PhDOpportunities

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Reposted by Devin Schweppe

Ryan Flynn @raflynn5.bsky.social · 1d

We’re excited to report work led by postdoc Jennifer Porat in the lab, finding that DNA accumulates on the surface of living cells and that the secreted extracellular protein DNASE1L3 can modulate its levels on B and T cells. With a new twist for ATAC-seq as well www.biorxiv.org/content/10.1...

DNASE1L3 surveils mitochondrial DNA on the surface of distinct mammalian cells

The extracellular space is a critical environment for discriminating self versus non-self nucleic acids and initiating the appropriate immune responses through signaling cascades to relay information ...

www.biorxiv.org

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Reposted by Devin Schweppe

Ruth Huttenhain @rhuttenhain.bsky.social · 6d

My lab @stanfordmedicine.bsky.social is recruiting! We are looking for a postdoc at the interface of quantitative proteomics and G protein-coupled receptor (GPCR) biology:
postdocs.stanford.edu/prospective/...
#TeamMassSpec #Proteomics #GPCR #Postdoc

Open Postdoctoral position, faculty mentor Ruth Huttenhain | Office of Postdoctoral Affairs

postdocs.stanford.edu

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Reposted by Devin Schweppe

Jacob (Yaqub) Hanna - يعقوب حنا @jacob-hanna.bsky.social · 11d

EEE meeting is BACK! Early Embryogenesis & Epigenetics conference in Berlin 02/2026.
Checkout great program and over 12 slots for (not so) short talks for submitted abstracts!. Early registration now open -
w.molgen.mpg.de/embryo2026

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Reposted by Devin Schweppe

Dr. Donita C. Brady of Brady Lab UPenn @bradylabupenn.bsky.social · 11d

🚨 Our 4th example of metalloallosteric regulation of kinase activity. Out today in @CellReports with @KJSsci. The ER stress sensor kinase PERK needs copper to work. Without copper, PERK can’t protect cells under stress. cell.com/cell-reports/p…

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Reposted by Devin Schweppe

Nobu Hamazaki @nobuhamazaki.bsky.social · 12d

New paper from my lab and @jshendure.bsky.social lab! Led by the brilliant @zukailiu.bsky.social and @cxqiu.bsky.social. We tackled how anterior and posterior progenitor cells cooperate to self-organize into an embryonic structure (termed AP-gastruloid). (1/n) www.biorxiv.org/content/10.1...

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Devin Schweppe @dschweppe.bsky.social · 14d

I’ve seen the concept, but haven't seen a hive in action, fun to think about api control for linked MSs though!

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Reposted by Devin Schweppe

Vivek Mutalik @vivekmutalik.bsky.social · 15d

#microsky

www.biorxiv.org/content/10.1...

Dosa: A method to covalently barcode proteins for high throughput biochemistry

Deep mutational scanning couples a proteins activity to DNA sequencing for high throughput assessment of the effects of all single amino acid substitutions, but it largely uses indirect assays, like g...

www.biorxiv.org

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Reposted by Devin Schweppe

Josh T Cuperus @rnanerd.bsky.social · 15d

www.biorxiv.org/content/10.1...

Dosa: A method to covalently barcode proteins for high throughput biochemistry

Deep mutational scanning couples a proteins activity to DNA sequencing for high throughput assessment of the effects of all single amino acid substitutions, but it largely uses indirect assays, like g...

www.biorxiv.org

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Devin Schweppe @dschweppe.bsky.social · 25d

Thanks! Though we may have hit a ceiling with that one 😬

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Devin Schweppe @dschweppe.bsky.social · 25d

Helios now out @ JPR: pubs.acs.org/doi/10.1021/...

Real-Time Instrument Control across Multiple Orbitrap Platforms through a Single Software Interface

Applications using real-time spectral analysis and real-time instrument control have emerged in recent years as powerful tools to improve the capabilities and sensitivity of mass spectrometers. Softwa...

pubs.acs.org

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Reposted by Devin Schweppe

Casey terHorst @ecoevolab.bsky.social · Sep 8

The GRFP lives!! (due end of October)
www.nsf.gov/funding/oppo...

NSF Graduate Research Fellowship Program (GRFP)

www.nsf.gov

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Devin Schweppe @dschweppe.bsky.social · Sep 8

Thanks to @proteomicsnews.bsky.social for the shoutout on Nova as well!

proteomicsnews.blogspot.com/2025/07/nova...

Nova! Build all the mass spec tools!

Playing catchup on posts this morning, I guess! This one looks super useful! Don't wanna read? I gotcha. https://schweppelab.github.io/N...

proteomicsnews.blogspot.com

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Devin Schweppe @dschweppe.bsky.social · Sep 8

Real-time API control of mass specs has been hard to get started (C#, VS, etc). Mike Hoopmann's recent work makes dev easier & more open!:

Nova - lightweight dev library
schweppelab.github.io/Nova/ pubs.acs.org/doi/full/10....

Helios - a unified instrument API now @ JPR
github.com/SchweppeLab/...

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Reposted by Devin Schweppe

Chris McGann @chrismcgann.bsky.social · Sep 5

After five great years, my journey in the Schweppe Lab and at UW has come to a close. Huge thanks to @dschweppe.bsky.social and all the amazing labmates for making graduate school such a wonderful experience. Extremely grateful for the memories and all the help I received along the way.

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Reposted by Devin Schweppe

Vaughn Cooper @vscooper.micropopbio.org · Aug 30

Let this one sink in.
www.nytimes.com/2025/08/28/w...

Pediatric Brain Cancer Group to Lose Federal Funding

www.nytimes.com

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Reposted by Devin Schweppe

Alex Merz 🇺🇸🇨🇦🇺🇦 @merz.bsky.social · Aug 28

I am delighted to announce that the UW Department of Biochemistry has opened searches for TWO tenure-track positions.

Descriptions and links in the following two posts.

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Reposted by Devin Schweppe

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · Aug 27

Spread the word - we at @stanford-chemh.bsky.social are searching to fill a new junior faculty at the interface of molecular and computational science. See link below!

Sarafan ChEM-H @stanford-chemh.bsky.social · Aug 26

Open faculty position!
We're seeking applicants for a tenure-track faculty position at the junior level (Assistant or untenured Associate Professor) with research programs that exist at the interface between molecular science and computation. Apply here: stanford.io/45MF3Qa

Open Faculty Position: Assistant or Associate (Untenured) Professor

Application deadline: 11:55 PM on Wednesday, October 15, 2025

Sarafan ChEM-H is seeking candidates with research programs that exist at the interface between molecular science and computation.

Click the link above to learn more & apply!

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Reposted by Devin Schweppe

Benjamin Furtwängler @bfurtwa.bsky.social · Aug 22

We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social.
www.science.org/doi/10.1126/...
🧵

Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics

Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...

www.science.org

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Reposted by Devin Schweppe

Marla Feller @mfeller.bsky.social · Aug 20

Come join our new Department of Neuroscience @ucberkeleyofficial.bsky.social as an Assistant Professor! aprecruit.berkeley.edu/JPF05041

Assistant Professor - Molecular, Cellular, and Developmental Neuroscience - Department of Neuroscience

University of California, Berkeley is hiring. Apply now!

aprecruit.berkeley.edu

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Reposted by Devin Schweppe

Julie Pfeiffer @jkpfeiff.bsky.social · Aug 18

Faculty search announcement 2025: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) www.utsouthwestern.edu/departments/...

Department members sit at a very long table in the hallway eating a pre-Thanksgiving potluck feast.

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Reposted by Devin Schweppe

Roshni Patel @roshnipatel.bsky.social · Aug 18

happy to say my new department is hiring an associate/full professor: academicjobsonline.org/ajo/jobs/30328

please apply!

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Reposted by Devin Schweppe

Jeff Martell @jeffmartell.bsky.social · Aug 14

Excited to share our new preprint, which was years in the making! chemrxiv.org/engage/chemr...
New reactions are typically developed by trial and error. How can we speed up this process? Read on to learn how we used DNA scaffolding to perform >500,000 parallel reactions on attomole scale.
1/n

DNA-Scaffolded Ultrahigh-Throughput Reaction Screening

Discovering and optimizing reactions is central to synthetic chemistry. However, chemical reactions are traditionally screened using relatively low-throughput methods, prohibiting exploration of diver...

chemrxiv.org

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Reposted by Devin Schweppe

Nikolai Slavov @slavov-n.bsky.social · Aug 7

The authors report that all seven tested deep learning models failed to outperform simple baselines in predicting transcriptome changes after single or double perturbations.

I will duck for cover.

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Reposted by Devin Schweppe

Keri Backus @keribackus.bsky.social · Aug 4

Daily Bruin article about the ~800 frozen grants at UCLA including some from my lab dailybruin.com/2025/08/02/a...

About 800 NIH, NSF research grants suspended following UCLA federal funding cuts - Daily Bruin

About 800 research grants have been suspended at UCLA, according to a Friday email from Vice Chancellor for Research and Creative Activities Roger Wakimoto. Wakimoto said in the email, which was sent ...

dailybruin.com

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