Edouard Hannezo
@ehannezo.bsky.social
1.8K followers 95 following 42 posts
Professor of Biophysics - @ISTAustria Using physics to understand biological questions, such as how embryos grow!
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ehannezo.bsky.social
Excited about the new work from Z. Dunajova & S. Tasciyan (with the Sixt lab @ISTA) - how the mechanical heterogeneity of the environment can be (by itself!) a driver of tumor cell dissemination! www.biorxiv.org/content/10.1... Combination of in vitro exp, simulations and KPZ stat phys!👇🧵1/n
Reposted by Edouard Hannezo
Reposted by Edouard Hannezo
davidbrueckner.bsky.social
How do cells navigate up gradients of adhesive proteins?
🤔

Termed "Haptotaxis", this effect is ubiquitous in cell migration, but it's mechanism was poorly understood

We show that passive friction directs cells & explains complex trajectories on gradients

👉 www.nature.com/articles/s41...
Reposted by Edouard Hannezo
akankshi.bsky.social
Our latest preprint! Into morphogenesis, Yap, ECM, signaling, vertex models, feedbacks/robustness? There is something here for everyone. We discovered a positive feedback loop that extends inner ear canals, and a built-in mechanism that shuts it down when morphogenesis is done. tinyurl.com/464wsjhd
ehannezo.bsky.social
Now out in final published form - with a new title "Mechanical control of cell fate decisions in the skin epidermis" and simulations/quantifications! See below for thread of how unbalanced tensions can bias fate choices in minimal 3D models of tissues! www.nature.com/articles/s41...
ehannezo.bsky.social
Happy to share the latest work from Preeti Sahu, with Adriana Sanchez-Danes on the biomechanics of cell fate choices during tumor initiation! We implement/test a 3D vertex model with proliferation and fate choices for multilayered tissues! See 🧵 below (1/n) bit.ly/3ZXxJzk
Reposted by Edouard Hannezo
kuba-sedzinski.bsky.social
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
ehannezo.bsky.social
Core achievement unlocked!! Congrats to Fabrizio amd all authors!!
istaresearch.bsky.social
Who knew that the perfect pasta sauce could lead to a Nobel Prize? Congrats to ISTA postdoc Fabrizio Olmeda and collaborators for winning the Ig Nobel Prize with their research on mastering Cacio e Pepe. Bravo! 🍝 🎉

Getting hungry? Here´s the recipe for delicious research: https://bit.ly/42vlpHm
Reposted by Edouard Hannezo
istaresearch.bsky.social
Who knew that the perfect pasta sauce could lead to a Nobel Prize? Congrats to ISTA postdoc Fabrizio Olmeda and collaborators for winning the Ig Nobel Prize with their research on mastering Cacio e Pepe. Bravo! 🍝 🎉

Getting hungry? Here´s the recipe for delicious research: https://bit.ly/42vlpHm
Reposted by Edouard Hannezo
bladoux.bsky.social
We’re organizing a conference at @ijmonod.bsky.social in Paris, January 2026, in memory of M.P. Sheetz — pioneer in cell mechanics and mechanobiology, co-discoverer of kinesin, and founder of @mbisg.bsky.social. Join us to explore his legacy.

mikeinmemoriam.sciencesconf.org
Reposted by Edouard Hannezo
davidbrueckner.bsky.social
Super excited that our group will be supported by an ERC Starting Grant!

In project "InfoFate" we will study how cells use information in dynamical, neighborhood & mechanical signals to make decisions.

We'll have PhD and Postdoc positions available, please get in touch if interested!
Reposted by Edouard Hannezo
paveltomancak.bsky.social
We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
Reposted by Edouard Hannezo
ulrichschwarz.bsky.social
📣 Now out in @physreve.bsky.social‬ as editors' suggestion: our theory on the role of different myosin II isoforms during cell migration. For standard parameters, A and B segregate to the front and the back, respectively. Yet for other parameter values, also oscillations are possible.
ehannezo.bsky.social
Very cool to see it out congratulations!!
Reposted by Edouard Hannezo
istaresearch.bsky.social
Do you want to push the boundaries of science together with world-class supervisors and colleagues?

The ISTA-Fellowship Program offers fully funded two-year postdoctoral fellowships for highly qualified candidates.

Apply now to take your next career step at ISTA: https://bit.ly/4kfKBZx
ehannezo.bsky.social
Very happy to see it out, another fun collaboration with the Sixt group at @istaresearch.bsky.social ! See Mehmet's thread for a summary of how different immune cells can "surf" on each other's self-generated gradients to drive efficient co-migration!
mehmetcanucar.bsky.social
🚨 New paper out in @pnas.org! 🚨

We show that self-generated gradients allow heterogeneous cell mixtures to co-migrate efficiently over long distances —while optimizing their physical interactions!

(See below for 🧵)

www.pnas.org/doi/10.1073/... 🧪
Reposted by Edouard Hannezo
mehmetcanucar.bsky.social
🚨 New paper out in @pnas.org! 🚨

We show that self-generated gradients allow heterogeneous cell mixtures to co-migrate efficiently over long distances —while optimizing their physical interactions!

(See below for 🧵)

www.pnas.org/doi/10.1073/... 🧪
Reposted by Edouard Hannezo
paveltomancak.bsky.social
Our first #Hydra paper. @anaisbailles.bsky.social all the way, with crucial theory contributions from Carl Modes and @zechnerlab.bsky.social Hydra maintenance by Heino Andreas and HCR by Giulia Serafini. Teamwork. Many thanks to the generous Hydra research community.
anaisbailles.bsky.social
Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
ehannezo.bsky.social
If you want to discover Vienna, Austria in general (and @istaresearch.bsky.social groups in particular) now have 4-year fellowships for postdocs coming from a US institution (up to 500,000 EUR)! Contact me if interested!
oeaw.bsky.social
25 neue #Stipendien für Forschende aus den #USA 🎓 Mit 10 Millionen Euro finanziert der Fonds Zukunft Österreich das von der ÖAW initiierte neue Programm APART-USA, das vierjährige Post-Doc-Stellen an österreichischen Universitäten oder Forschungseinrichtungen schafft ⤵️
www.oeaw.ac.at/news/oeaw-25...
ÖAW: 25 neue Stipendien für Forschende aus den USA
FZÖ finanziert Akademie-Programm mit 10 Millionen Euro, um Post-Docs unbürokratisch aus den USA zu holen ++ Faßmann: „Richtiges Zeichen in diesen bewegten Zeiten“
www.oeaw.ac.at
Reposted by Edouard Hannezo
richardsever.bsky.social
bioRxiv bat signal going up. We have a big backlog of submissions. If any affiliates have time to do some screening, we (and all the authors) would be immensely grateful! 🙏
Reposted by Edouard Hannezo
cerbino.bsky.social
1/ 🚀 New tutorial alert!
Ever wanted to use your microscope as a multi-angle light scattering device? Our new preprint is out:
📄 The Hitchhiker’s Guide to Differential Dynamic Microscopy (DDM)
arXiv: 2507.05058 (link in the last skeet!)
🧵 Thread ⬇️
Reposted by Edouard Hannezo