Elodie Lafont
@elodie-lafont.bsky.social
1.1K followers
2K following
20 posts
PhD in Oncology. Researcher (CRCN INSERM), Cancer research, Cell Biology, Cell Signalling, PTMs #WomeninSTEM
@csignaling.bsky.social
https://oss-clcc.univ-rennes.fr/
https://scholar.google.com/citations?user=2ZoLzg4AAAAJ&hl=fr
ORCID 0000-0003-1978-749
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Elodie Lafont
@elodie-lafont.bsky.social
· Nov 18
IRE1 RNase controls CD95-mediated cell death | EMBO reports
imageimageDual regulation of Cell Death Receptor CD95 signalling by ER stress sensor IRE1. IRE1,
a mediator of the unfolded protein response (UPR), governs CD95/Fas expression and
CD95L-induced cell d...
doi.org
Reposted by Elodie Lafont
Reposted by Elodie Lafont
Reposted by Elodie Lafont
Reposted by Elodie Lafont
Reposted by Elodie Lafont
Reposted by Elodie Lafont
Reposted by Elodie Lafont
Reposted by Elodie Lafont
Olivia Coleman
@ocoleman.bsky.social
· Sep 2
ATF6 activation alters colonic lipid metabolism causing tumour-associated microbial adaptation - Nature Metabolism
The transcription factor ATF6 causes an enrichment in long-chain fatty acids in the colonic epithelium, which leads to changes in the gut microbiota and contributes to the development of colorectal ca...
www.nature.com
Reposted by Elodie Lafont
Reposted by Elodie Lafont
Eric Chevet
@ericchevet.bsky.social
· Aug 23
Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy - Nature
Perineural invasion and cancer-induced nerve injury of tumour-associated nerves are associated with poor response to anti-PD-1 therapy, which can be reversed by combining anti-PD-1 therapy with a...
www.nature.com
Reposted by Elodie Lafont
Eric Chevet
@ericchevet.bsky.social
· Aug 23
ER-phagy and proteostasis defects prime pancreatic epithelial state changes in KRAS-mediated oncogenesis
Salomo-Coll et al. show that pre-cancerous acinar-ductal metaplasia emerging upon
Kras mutation in pancreas is driven by downregulation of CCPG1-mediated acinar ER-phagy,
resulting in defective cleara...
www.cell.com
Reposted by Elodie Lafont
Reposted by Elodie Lafont