Esau J. Estrada
@esaujestrada.bsky.social
Current UW-Madison Research Specialist | Former UMass Chan PREP Scholar | UCSD Alumni #first gen
Reposted by Esau J. Estrada
In a memo obtained by STAT, the NIH gives specific steps on how grant reviewers can check for alignment with administration priorities.
www.statnews.com/2025/12/15/n...
www.statnews.com/2025/12/15/n...
NIH specifies how grant reviewers should ensure alignment with Trump priorities
In a memo obtained by STAT, the NIH gives specific steps on how grant reviewers can check for alignment with administration priorities.
www.statnews.com
December 15, 2025 at 8:04 PM
In a memo obtained by STAT, the NIH gives specific steps on how grant reviewers can check for alignment with administration priorities.
www.statnews.com/2025/12/15/n...
www.statnews.com/2025/12/15/n...
Reposted by Esau J. Estrada
A 5-day protocol to generate hiPSC 3D Vascular Organoid😎
ETV2▶️Endothelial Cell
NKX3.1▶️Mural Cell
👉Perfusable, arteriovenous network in vivo
👉⏫Reperfusion in mouse diabetic limb ischemia
👉⏫transplanted islet performance
@meleromartinlab.bsky.social #CellStemCell 2025
www.cell.com/cell-stem-ce...
ETV2▶️Endothelial Cell
NKX3.1▶️Mural Cell
👉Perfusable, arteriovenous network in vivo
👉⏫Reperfusion in mouse diabetic limb ischemia
👉⏫transplanted islet performance
@meleromartinlab.bsky.social #CellStemCell 2025
www.cell.com/cell-stem-ce...
December 14, 2025 at 12:53 PM
A 5-day protocol to generate hiPSC 3D Vascular Organoid😎
ETV2▶️Endothelial Cell
NKX3.1▶️Mural Cell
👉Perfusable, arteriovenous network in vivo
👉⏫Reperfusion in mouse diabetic limb ischemia
👉⏫transplanted islet performance
@meleromartinlab.bsky.social #CellStemCell 2025
www.cell.com/cell-stem-ce...
ETV2▶️Endothelial Cell
NKX3.1▶️Mural Cell
👉Perfusable, arteriovenous network in vivo
👉⏫Reperfusion in mouse diabetic limb ischemia
👉⏫transplanted islet performance
@meleromartinlab.bsky.social #CellStemCell 2025
www.cell.com/cell-stem-ce...
Reposted by Esau J. Estrada
Reposted by Esau J. Estrada
Honored to receive the 2025 @urochestersmd.bsky.social Trainee Mentoring Award in Basic Science. Grateful to Drs. @johnfoxe.bsky.social Foxe & Kerry O’Banion, my mentees, staff, and colleagues. Mentoring is my passion—thank you, trainees. #mentorship #URResearch2025
December 12, 2025 at 3:12 AM
Honored to receive the 2025 @urochestersmd.bsky.social Trainee Mentoring Award in Basic Science. Grateful to Drs. @johnfoxe.bsky.social Foxe & Kerry O’Banion, my mentees, staff, and colleagues. Mentoring is my passion—thank you, trainees. #mentorship #URResearch2025
Reposted by Esau J. Estrada
I couldn’t leave Chicago without getting a cut from my old barber, Zariff!
December 11, 2025 at 11:56 PM
I couldn’t leave Chicago without getting a cut from my old barber, Zariff!
Reposted by Esau J. Estrada
Reposted by Esau J. Estrada
The outlook for patients with certain forms of fibrosis has finally started to brighten, after a string of clinical trial setbacks over the past decade. In October @US_FDA approved @Boehringer's oral drug Jascayd (nerandomilast) for idiopathic pulmonary fibrosis www.nature.com/articles/s41...
FDA approves new mechanism to treat idiopathic pulmonary fibrosis, expanding limited arsenal - Nature Biotechnology
The first-in-class small molecule Jascayd targets a fibrotic signaling cascade, offering new hope in a stagnant therapeutic field, as several other programs near maturity.
www.nature.com
December 11, 2025 at 5:16 PM
The outlook for patients with certain forms of fibrosis has finally started to brighten, after a string of clinical trial setbacks over the past decade. In October @US_FDA approved @Boehringer's oral drug Jascayd (nerandomilast) for idiopathic pulmonary fibrosis www.nature.com/articles/s41...
Reposted by Esau J. Estrada
In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles - @uclpophealthsci.bsky.social go.nature.com/4a39S6X
In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles - Nature Biotechnology
Virus-like particles are engineered to edit human hematopoietic cells in vivo.
go.nature.com
December 8, 2025 at 6:53 PM
In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles - @uclpophealthsci.bsky.social go.nature.com/4a39S6X
Reposted by Esau J. Estrada
Sharing an identity w/ study participants, health equity awards, widely read papers — all positives in the past
But this year, they're being weaponized against trans researchers
@theresagaff.bsky.social w/ the next part of American Science, Shattered
www.statnews.com/2025/12/09/h...
But this year, they're being weaponized against trans researchers
@theresagaff.bsky.social w/ the next part of American Science, Shattered
www.statnews.com/2025/12/09/h...
Early-career trans researchers reconsider their futures amid lost funding and fear
The chaos created by the freezing and termination of billions of dollars of research grants has left trans academics especially vulnerable.
www.statnews.com
December 9, 2025 at 2:46 PM
Sharing an identity w/ study participants, health equity awards, widely read papers — all positives in the past
But this year, they're being weaponized against trans researchers
@theresagaff.bsky.social w/ the next part of American Science, Shattered
www.statnews.com/2025/12/09/h...
But this year, they're being weaponized against trans researchers
@theresagaff.bsky.social w/ the next part of American Science, Shattered
www.statnews.com/2025/12/09/h...
Reposted by Esau J. Estrada
This #GivingTuesday, consider making a tax-deductible donation to @colorsofthebrain.bsky.social ! All funds are invested directly into research funding support for the 2025 cohort and the incoming 2026 cohort of scholars donorbox.org/cob-kibm-sch...
CoB-KIBM Scholars Program 2025 | COLORS OF THE BRAIN (Powered by Donorbox)
Colors of the Brain [email protected] MISSIONColors of the Brain is committed to diversifying STEM graduate education and academia. We support undergraduates from histo...
donorbox.org
December 2, 2025 at 7:26 PM
This #GivingTuesday, consider making a tax-deductible donation to @colorsofthebrain.bsky.social ! All funds are invested directly into research funding support for the 2025 cohort and the incoming 2026 cohort of scholars donorbox.org/cob-kibm-sch...
Reposted by Esau J. Estrada
Research Highlight: Designer voltage-gated anion channels suppress neuronal firing www.nature.com/articles/s41...
Designer voltage-gated anion channels suppress neuronal firing - Nature Biotechnology
Nature Biotechnology - Designer voltage-gated anion channels suppress neuronal firing
www.nature.com
November 24, 2025 at 3:38 PM
Research Highlight: Designer voltage-gated anion channels suppress neuronal firing www.nature.com/articles/s41...
Reposted by Esau J. Estrada
New JAMA internal medicine study finds 74,000 people could be affected in NIH funding cuts to clinical trials, @adithi-r1.bsky.social reports
www.statnews.com/2025/11/17/n...
www.statnews.com/2025/11/17/n...
NIH funding cuts have affected over 74,000 people enrolled in experiments, a new report says
Over 74,000 people enrolled in experiments have been affected by the NIH's funding cuts, according to a new report.
www.statnews.com
November 17, 2025 at 9:00 PM
New JAMA internal medicine study finds 74,000 people could be affected in NIH funding cuts to clinical trials, @adithi-r1.bsky.social reports
www.statnews.com/2025/11/17/n...
www.statnews.com/2025/11/17/n...
Reposted by Esau J. Estrada
Really cool stuff on #pericytes @natureportfolio.nature.com !
Non-invasive characterization of pericyte dysfunction in mouse brain using functional ultrasound localization microscopy - Nature Biomedical Engineering
An optimized pipeline for functional ultrasound localization microscopy is safely and non-invasively applied to detect and characterize early microvascular alterations with high spatial and temporal r...
www.nature.com
August 11, 2025 at 9:55 PM
Really cool stuff on #pericytes @natureportfolio.nature.com !
Reposted by Esau J. Estrada
A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function go.nature.com/4mc1SmQ
A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function - Nature Biotechnology
RNA-binding motifs in eukaryotic proteins are presented in a comprehensive resource.
go.nature.com
July 25, 2025 at 3:46 PM
A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function go.nature.com/4mc1SmQ
Reposted by Esau J. Estrada
#sciencejobs
Lab manager position 💪🏻
Lab manager position 💪🏻
I'm recruiting a lab manager for my soon-to-be-launched lab at Ohio State! If you know of any recent grads who may be interested both in helping to build the lab and in developing skills in the cognitive neuroscience of memory, please share!
osu.wd1.myworkdayjobs.com/en-US/OSUCar...
osu.wd1.myworkdayjobs.com/en-US/OSUCar...
Research Associate
Screen reader users may encounter difficulty with this site. For assistance with applying, please contact [email protected]. If you have questions while submitting an application, pleas...
osu.wd1.myworkdayjobs.com
July 24, 2025 at 11:23 PM
#sciencejobs
Lab manager position 💪🏻
Lab manager position 💪🏻
Reposted by Esau J. Estrada
#SpatialTranscriptomics #Atherosclerosis
Mapping the Senescence (SenMayo CellAge) in p16 reporter🐭aortic atherosclerotic lesions
scRNAseq GeoMx
🔥 #SmoothMuscleCell Fibroblast T
#Senolytic ABT-737 ⏫plaque collagen fibers ⏬necrotic core ⏬serum cytokines
#NatAging 2025
www.nature.com/articles/s43...
Mapping the Senescence (SenMayo CellAge) in p16 reporter🐭aortic atherosclerotic lesions
scRNAseq GeoMx
🔥 #SmoothMuscleCell Fibroblast T
#Senolytic ABT-737 ⏫plaque collagen fibers ⏬necrotic core ⏬serum cytokines
#NatAging 2025
www.nature.com/articles/s43...
July 15, 2025 at 7:17 PM
#SpatialTranscriptomics #Atherosclerosis
Mapping the Senescence (SenMayo CellAge) in p16 reporter🐭aortic atherosclerotic lesions
scRNAseq GeoMx
🔥 #SmoothMuscleCell Fibroblast T
#Senolytic ABT-737 ⏫plaque collagen fibers ⏬necrotic core ⏬serum cytokines
#NatAging 2025
www.nature.com/articles/s43...
Mapping the Senescence (SenMayo CellAge) in p16 reporter🐭aortic atherosclerotic lesions
scRNAseq GeoMx
🔥 #SmoothMuscleCell Fibroblast T
#Senolytic ABT-737 ⏫plaque collagen fibers ⏬necrotic core ⏬serum cytokines
#NatAging 2025
www.nature.com/articles/s43...
Reposted by Esau J. Estrada
A Lost Generation of Researchers: Cuts to the nation’s science funding are forcing future scholars to delay graduate study, continue it abroad, or forgo it entirely. @mzahneis.bsky.social reports www.chronicle.com/article/a-lo...
How Trump’s Cuts to Science Funding Are Derailing Young Scholars’ Careers
Budding academics are delaying their graduate studies, continuing them abroad, or forgoing them entirely.
www.chronicle.com
July 7, 2025 at 9:48 PM
A Lost Generation of Researchers: Cuts to the nation’s science funding are forcing future scholars to delay graduate study, continue it abroad, or forgo it entirely. @mzahneis.bsky.social reports www.chronicle.com/article/a-lo...
Reposted by Esau J. Estrada
More 1st year grad students unable to find a lab because of funding shortages in rotation-based programs. #fundingcuts
What advice would you give to an incoming 1st year to try avoid this?
What advice would you give to an incoming 1st year to try avoid this?
July 5, 2025 at 3:08 PM
More 1st year grad students unable to find a lab because of funding shortages in rotation-based programs. #fundingcuts
What advice would you give to an incoming 1st year to try avoid this?
What advice would you give to an incoming 1st year to try avoid this?
Reposted by Esau J. Estrada
This is cool. An archaeal species with no metabolic genes. Just replicative genes (ribosomes, messenger and transfer RNAs). 238kb genome.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 26, 2025 at 10:06 PM
This is cool. An archaeal species with no metabolic genes. Just replicative genes (ribosomes, messenger and transfer RNAs). 238kb genome.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Esau J. Estrada
Big #T1D news! Vertex has published their phase 1–2 trial of stem cell-derived islets (VX880, now called zimislecel). All 12 full-dose patients had reduced insulin need, and 10 no longer require insulin injections. Major step forward to a functional cure! www.nejm.org/doi/full/10....
Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM
Zimislecel is an allogeneic stem cell–derived islet-cell therapy. Data on the safety and efficacy of zimislecel in persons with type 1 diabetes are needed. We conducted a phase 1–2 study of zimisle...
www.nejm.org
June 23, 2025 at 2:44 PM
Big #T1D news! Vertex has published their phase 1–2 trial of stem cell-derived islets (VX880, now called zimislecel). All 12 full-dose patients had reduced insulin need, and 10 no longer require insulin injections. Major step forward to a functional cure! www.nejm.org/doi/full/10....
Reposted by Esau J. Estrada
Reposted by Esau J. Estrada
President Trump's anti-immigrant policies are creating a climate of fear, robbing people of their time and their quality of life.
Our communities deserve better.
Our communities deserve better.
For Undocumented Immigrants, Being ‘Good’ Is Not Good Enough | ACLU
www.aclu.org
May 24, 2025 at 5:22 PM
President Trump's anti-immigrant policies are creating a climate of fear, robbing people of their time and their quality of life.
Our communities deserve better.
Our communities deserve better.
Reposted by Esau J. Estrada
My continued biomedical education
Endothelin-1 signaling in the kidney: recent advances & remaining gaps
Circadian & MicroRNA➡️ET-1 signaling
Clinical trials #EndothelinReceptorAntagonist in cardiorenal diseases
@carmendemigue12.bsky.social #AJPRenal 2025
journals.physiology.org/doi/full/10....
Endothelin-1 signaling in the kidney: recent advances & remaining gaps
Circadian & MicroRNA➡️ET-1 signaling
Clinical trials #EndothelinReceptorAntagonist in cardiorenal diseases
@carmendemigue12.bsky.social #AJPRenal 2025
journals.physiology.org/doi/full/10....
May 19, 2025 at 1:37 PM
My continued biomedical education
Endothelin-1 signaling in the kidney: recent advances & remaining gaps
Circadian & MicroRNA➡️ET-1 signaling
Clinical trials #EndothelinReceptorAntagonist in cardiorenal diseases
@carmendemigue12.bsky.social #AJPRenal 2025
journals.physiology.org/doi/full/10....
Endothelin-1 signaling in the kidney: recent advances & remaining gaps
Circadian & MicroRNA➡️ET-1 signaling
Clinical trials #EndothelinReceptorAntagonist in cardiorenal diseases
@carmendemigue12.bsky.social #AJPRenal 2025
journals.physiology.org/doi/full/10....
Reposted by Esau J. Estrada
Check out our latest profile! Dr. Eve Marder studies the stability and flexibility of neural circuit function. Follow the link below to learn more!
www.storiesofwin.org/profiles/202...
#StoriesofWiN #WomenInNeuroscience #WomenInNeuro
www.storiesofwin.org/profiles/202...
#StoriesofWiN #WomenInNeuroscience #WomenInNeuro
May 14, 2025 at 4:15 PM
Check out our latest profile! Dr. Eve Marder studies the stability and flexibility of neural circuit function. Follow the link below to learn more!
www.storiesofwin.org/profiles/202...
#StoriesofWiN #WomenInNeuroscience #WomenInNeuro
www.storiesofwin.org/profiles/202...
#StoriesofWiN #WomenInNeuroscience #WomenInNeuro
Reposted by Esau J. Estrada
New online! Lassoing bacterial ribosomes
Lassoing bacterial ribosomes
Nature Reviews Microbiology, Published online: 14 April 2025; doi:10.1038/s41579-025-01182-xThis study reports the identification of a ribosome-targeting lasso peptide that acts on a new ribosomal binding site.
www.nature.com
April 14, 2025 at 4:26 PM
New online! Lassoing bacterial ribosomes