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gerrich.bsky.social
Gerrich
@gerrich.bsky.social
980 followers 1.2K following 390 posts
Non-conventional microbes, metabolic engineering and microbial genetics. Bacteria go brrr Finally, finished with my thesis, now off to new frontiers! https://orcid.org/0009-0004-1949-532X
orcid.org
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gerrich.bsky.social
Gerrich @gerrich.bsky.social · Jan 7
My last thesis paper post:
This one is for plasmid enthusiasts.
Comparing seven different replication system for application in the Zymomonas mobilis.
The pBBR1 replicon and six replicons from native Z. mobilis plasmids of different strains.

Published in @microbiotech.bsky.social 🧪
Construction and comparison of different vehicles for heterologous gene expression in Zymomonas mobilis
In this study, a series of shuttle vectors compatible with modular cloning were constructed based on the replication mechanisms of the native Z. mobilis plasmids pZMO1, pZMOB04, pZMOB05, pZMOB06, pZM...
doi.org
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Reposted by Gerrich
asm.org
ASM @asm.org · 58m
It’s time to let your creativity grow! Submit your entry for this year’s Agar Art Contest: Microbes Make the World Go Round. From food and health to climate and beyond, microbes shape our lives—now show us your story in agar! Submit by Oct. 26: asm.social/2Dt
Pain palette with microbes as the paint swatches.
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Reposted by Gerrich
daganlab.bsky.social
DaganLab @daganlab.bsky.social · 8h
Happy to introduce SegMantX. Analyzing #plasmid we find that most duplications are MGE-driven. Additional use cases include detection of DNA transfer between replicons and examination of plasmid sequence similarity. Try it out! doi.org/10.1093/molb...
SegMantX: a novel tool for detecting DNA duplications uncovers prevalent duplications in plasmids
Abstract. Segmental duplications play an important role in genome evolution via their contribution to copy-number variation, gene-family diversification an
doi.org
4 6
Reposted by Gerrich
kjerstiekeland.bsky.social
Christie @kjerstiekeland.bsky.social · 1d
when the predicted protein model is a total disaster
zinc finger homunculus that says “it feels like you fucked this up”
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nizet.bsky.social
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 2d
Will Ferrell as multidrug-resistant bacterial pathogen threats #AMR #MicroSky #IDSky
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Reposted by Gerrich
oborkowski.bsky.social
Olivier Borkowski @oborkowski.bsky.social · 1d
SHARK: a specialized host for assembling R6K plasmids
doi.org/10.1101/2025...
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Reposted by Gerrich
dmattanovich.bsky.social
Diethard Mattanovich @dmattanovich.bsky.social · 2d
8 PhD projects announced in a joint programme of BOKU University @bokuvienna.bsky.social TU Vienna @tuwien.at University Vienna @univie.ac.at on Green Chemistry!
Check details via the link ⬇️
The first 2 projects will be realised in my lab at BOKU.
www.tuwien.at/greenchem/en...
A watercolor rendering of a combined electrochemical reduction of CO2 to methanol with yeast based conversion of methanol to chemicals
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godi.bsky.social
Jelena Godrijan 🫧❾🌊🦋 @godi.bsky.social · 3d
⚠️New paper ➡️ isolating >600 freshwater microbes using dilution-to-extinction and low-nutrient, lake-mimicking media.

🤯Expands cultured diversity to ~70 % of detected genera and enables physiological studies of streamlined oligotrophs.

🔗 www.nature.com/articles/s41...
#protistsonsky
Bringing the uncultivated microbial majority of freshwater ecosystems into culture - Nature Communications
A large fraction of aquatic bacteria remains uncultured. Here, the authors cultivated 627 strains of abundant freshwater bacteria from 14 European lakes, thus generating a collection that includes many previously uncultured, oligotrophic bacteria that may serve as model organisms.
www.nature.com
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Reposted by Gerrich
edwardteng.bsky.social
Edward T Eng @edwardteng.bsky.social · 4d
Muyuan Chen has turned structural biology into an immersive experience with his new video game Meowtabolism, now available on Steam.
Try the demo here: store.steampowered.com/app/4045010/...
Give Muyuan feedback: steamcommunity.com/app/4045010
#ScienceGaming #StructuralBiology #CryoEM #STEMOutreach
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anneapplebaum.bsky.social
Anne Applebaum @anneapplebaum.bsky.social · 4d
President Macron:
“We were very naive to leave our public space to social media networks controlled by US or Chinese companies that don’t share our interests and not interested in survival of our democracies.”
www.youtube.com/watch?v=MggN...
French President Macron Speaks at German Unity Day Ceremony | WION LIVE
YouTube video by WION
www.youtube.com
230 2.7K 7.8K
gerrich.bsky.social
Gerrich @gerrich.bsky.social · 4d
@synbio1.bsky.social

I guess one can biologize biological processes and go even more archaic/futuristic.
jenlucpiquant.bsky.social
Jennifer Ouellette @jenlucpiquant.bsky.social · 5d
Scientists revive old Bulgarian recipe to make yogurt with ants. Ants carry lactic and acetic acid bacteria that help coagulate milk, as well as formic acid to acidify it. They even partnered with Danish chefs to create three recipes using ant yogurt. arstechnica.com/science/2025...
Scientists revive old Bulgarian recipe to make yogurt with ants
Ants carry lactic and acetic acid bacteria that help coagulate milk, as well as formic acid to acidify it.
arstechnica.com
1 1 4
Reposted by Gerrich
jenlucpiquant.bsky.social
Jennifer Ouellette @jenlucpiquant.bsky.social · 5d
Scientists revive old Bulgarian recipe to make yogurt with ants. Ants carry lactic and acetic acid bacteria that help coagulate milk, as well as formic acid to acidify it. They even partnered with Danish chefs to create three recipes using ant yogurt. arstechnica.com/science/2025...
Scientists revive old Bulgarian recipe to make yogurt with ants
Ants carry lactic and acetic acid bacteria that help coagulate milk, as well as formic acid to acidify it.
arstechnica.com
17 33 130
Reposted by Gerrich
odedrechavi.bsky.social
Oded Rechavi @odedrechavi.bsky.social · 5d
Friday Papers Club! 🍿In light of Pubmed going down, the collapse of social media, and my recent success at getting recommendations for interesting papers from those still around, I am starting a new tradition! - Recommend a good scientific manuscript! 👇
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gerrich.bsky.social
Gerrich @gerrich.bsky.social · 5d
I really love this experimental study on emergence of plasmid stability by @daganlab.bsky.social

They cleverly mimicked fluctuations in antibiotic levels to catch the evolution of stable plasmids that still carry antibiotic resistance.

Very insightful for plasmid evolution!
Emergence of plasmid stability under non-selective conditions maintains antibiotic resistance - Nature Communications
It is expected that plasmids are costly and therefore that selection is required to maintain them within bacterial populations. Here, Wein et al. show that plasmid stability can emerge even in the absence of positive selection and that loss may be determined by transcription-replication conflict.
www.nature.com
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gerrich.bsky.social
Gerrich @gerrich.bsky.social · 5d
'hey mela' is the first vegan pregnancy test in the world. Now available in Germany.

What could be vegan about it?

These tests are based on antibodies that are usually farmed from small rodents kept in cages, infected with hybridoma cells.

This test is based on AB expressed from algae!! 🧪
In my left hand I am holding the package of the 'hey mela' pregnancy test. The first vegan pregnancy test in the world. Now available in Germany.
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Reposted by Gerrich
danvec.bsky.social
Danve Castroverde @danvec.bsky.social · 5d
Engineered geminivirus replicons enable rapid in planta directed evolution

www.science.org/doi/10.1126/...
Engineered geminivirus replicons enable rapid in planta directed evolution
Directed evolution can rapidly generate genetic variants with new and enhanced properties, yet efficient platforms for performing such evolution directly in plant cells have been lacking. We developed...
www.science.org
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Reposted by Gerrich
giuliotesei.bsky.social
Giulio Tesei @giuliotesei.bsky.social · 6d
I'm hiring for a PhD position at Malmö University, Sweden!

The project will focus on molecular modelling of proteins, lipids, and biomolecular condensates at cell membranes.

More details and application form: tinyurl.com/4zm92365

Please feel free to share!

@vetenskapsradet.bsky.social | @mau.se
Snapshot of a condensate near a lipid membrane with Swedish Research Council and Malmö University logos.
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leibnizipk.bsky.social
Leibniz IPK @leibnizipk.bsky.social · 6d
You have a strong interest in plant genetics and root biology? You have experience with modern genetic, genomic, and bioinformatic method? And you hold a PhD in plant science, molecular biology, or genetics? Then we have a great job offer!

➡️Read more: tinyurl.com/2pyc68cu
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gerrich.bsky.social
Gerrich @gerrich.bsky.social · 8d
Here the 'm' of mRUBY is important.

My 'm'um made those pants for me, as I couldn't find any in this color for men.

But yeah, I think they match the hue of some of your flower variants well.

Looking forward to seeing your growing collection!
1
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ajfedorec.bsky.social
Alex Fedorec @ajfedorec.bsky.social · 9d
The advert for the second (wetlab) postdoc is now live www.ucl.ac.uk/work-at-ucl/...
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gerrich.bsky.social
Gerrich @gerrich.bsky.social · 9d
I finally picked up my "Epi-Bouquet 2" by @nickdesnoyer.bsky.social

As a former plant scienctist I am loving it! It's a great shirt! 💐 🧪

You can find more on Nick at his website: www.nickdesnoyer.com/about
Me standing on a street with trees in autumn colors. I am standing with my back to the camera. The focus of the photo is the T-shirt I am wearing , designed by Nick Desnoyer. On the back of the shirt you can see a bouquet made from engineered colorful Arabidopsis thaliana flowers in a small reaction tube, 'SynBio' is written underneath.
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odedrechavi.bsky.social
Oded Rechavi @odedrechavi.bsky.social · 9d
Got to love studies that were clearly conducted "for the love of the game" (“self-decapitating sea slugs”, “plants that see and use that for mimicry”, “worms that jump in the air”, aka papers you sometimes find in @currentbiology.bsky.social
) References to all of this bellow👇
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zaminiqbal.bsky.social
Zamin Iqbal @zaminiqbal.bsky.social · 12d
Apologies, forgot to add the actual paper link!!!!!

www.science.org/doi/10.1126/...
Pre- and postantibiotic epoch: The historical spread of antimicrobial resistance
Plasmids are now the primary vectors of antimicrobial resistance, but our understanding of how human industrialisation of antibiotics influenced their evolution is limited by a paucity of data predati...
www.science.org
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Reposted by Gerrich
zaminiqbal.bsky.social
Zamin Iqbal @zaminiqbal.bsky.social · 12d
Secondly, on staring at the data, we realised plasmids did not just evolve through the normal processes (mutation, gene gain/loss, inversion, etc). It seems plasmid fusion is an important process - many of the historical plasmids are now present embedded inside vast modern plasmids.
11/n
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zaminiqbal.bsky.social
Zamin Iqbal @zaminiqbal.bsky.social · 12d
Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
Thread 1/n
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vdlorenzo.bsky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 14d
Who is afraid of HGT? True, antibiotic resistances disseminate through it. But we can also leverage the same channels for spreading good stuff at a very large scale and fortifying the env microbiome with beneficial activities www.biorxiv.org/content/10.1... by Victor Maull & @ricardsole.bsky.social
Synthetic Horizontal Gene Transfer for Ecosystem Restoration
Restoring endangered ecosystems has become a pressing issue as the effects of global warming continue to harm existing communities. Over the last decade, several studies have suggested the use of synt...
www.biorxiv.org
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