GIMM Institute
@gimminstitute.bsky.social
A big world needs a little curiosity.
Welcome to the oficial Gulbenkian Institute for Molecular Medicine account. We are On the Verge of Discovery.
www.gimm.pt
Welcome to the oficial Gulbenkian Institute for Molecular Medicine account. We are On the Verge of Discovery.
www.gimm.pt
Can we say that Quirky Luísa made the thymus look better than ever? This was her interpretation of Ana Espada de Sousa’s lab work on immunodeficiency and how T cells develop in the thymus. 💜
Did this make it easier to understand the important work we do? 😊
Did this make it easier to understand the important work we do? 😊
February 2, 2026 at 5:39 PM
Can we say that Quirky Luísa made the thymus look better than ever? This was her interpretation of Ana Espada de Sousa’s lab work on immunodeficiency and how T cells develop in the thymus. 💜
Did this make it easier to understand the important work we do? 😊
Did this make it easier to understand the important work we do? 😊
Learn from leading experts how to generate and analyze single-cell RNA-seq (scRNA-seq) data at the next @embo.org Practical Course, taking place in Oeiras from May 18th to 23rd. 🧫
February 2, 2026 at 4:38 PM
Learn from leading experts how to generate and analyze single-cell RNA-seq (scRNA-seq) data at the next @embo.org Practical Course, taking place in Oeiras from May 18th to 23rd. 🧫
Two projects from the clinical and research teams of ULS Santa Maria, GIMM, and Faculdade de Medicina da Universidade de Lisboa were each awarded Flagship Research Project funding of up to €200,000.
A big step forward for sepsis and hereditary cancer! 💜
A big step forward for sepsis and hereditary cancer! 💜
February 2, 2026 at 3:30 PM
Two projects from the clinical and research teams of ULS Santa Maria, GIMM, and Faculdade de Medicina da Universidade de Lisboa were each awarded Flagship Research Project funding of up to €200,000.
A big step forward for sepsis and hereditary cancer! 💜
A big step forward for sepsis and hereditary cancer! 💜
Reposted by GIMM Institute
📢 Join us in sunny Lisbon 🇵🇹 2-5 June for the @embo.org workshop ☀️
“The rules of the game: biophysical & molecular principles in cellular evolution”
Apply by March 1st!
Please repost to help spread the word!
meetings.embo.org/event/26-cel...
#EMBORulesOfTheGame @gimmfoundation.bsky.social
“The rules of the game: biophysical & molecular principles in cellular evolution”
Apply by March 1st!
Please repost to help spread the word!
meetings.embo.org/event/26-cel...
#EMBORulesOfTheGame @gimmfoundation.bsky.social
The rules of the game: biophysical & molecular principles in cellular evolution
Cells are the fundamental units of life, shaped by evolution into a remarkable diversity of forms and functions. Much is known about the roles of genes and proteins, the regulation of molecular proce…
meetings.embo.org
December 18, 2025 at 3:48 PM
📢 Join us in sunny Lisbon 🇵🇹 2-5 June for the @embo.org workshop ☀️
“The rules of the game: biophysical & molecular principles in cellular evolution”
Apply by March 1st!
Please repost to help spread the word!
meetings.embo.org/event/26-cel...
#EMBORulesOfTheGame @gimmfoundation.bsky.social
“The rules of the game: biophysical & molecular principles in cellular evolution”
Apply by March 1st!
Please repost to help spread the word!
meetings.embo.org/event/26-cel...
#EMBORulesOfTheGame @gimmfoundation.bsky.social
Reposted by GIMM Institute
New research led by @karinaxavierlab.bsky.social at 🇵🇹 @gimmfoundation.bsky.social demonstrates that a harmless strain of 🦠 #Klebsiella – discovered by chance in 🧫 laboratory experiments – can eliminate #infections and reduce gut inflammation in mouse models of inflammatory bowel disease. #IBD
Klebsiella strain to protect against IBD gut infections
A team of researchers led by Karina Xavier has uncovered a promising new live biotherapeutic agent that may redefine how the medical field approaches microbiota-based therapies.
healthcare-in-europe.com
December 22, 2025 at 8:17 AM
New research led by @karinaxavierlab.bsky.social at 🇵🇹 @gimmfoundation.bsky.social demonstrates that a harmless strain of 🦠 #Klebsiella – discovered by chance in 🧫 laboratory experiments – can eliminate #infections and reduce gut inflammation in mouse models of inflammatory bowel disease. #IBD
Reposted by GIMM Institute
Depois de anos de muito trabalho, tive a honra de ser premiada com Melhor Trabalho de PhD na ULisboa. 🏅
Agradeço aos meus orientadores João Lacerda, Rita Azevedo e Maria Soares, aos voluntários, ao JLacerda Lab, à FMUL, e à @gimmfoundation.bsky.social.
Em breve, a defesa para fechar este ciclo! 👩🔬
Agradeço aos meus orientadores João Lacerda, Rita Azevedo e Maria Soares, aos voluntários, ao JLacerda Lab, à FMUL, e à @gimmfoundation.bsky.social.
Em breve, a defesa para fechar este ciclo! 👩🔬
Premiados ULisboa - redeSAÚDE 2025
A redeSAÚDE, rede temática interdisciplinar de Saúde da Universidade de Lisboa, atribuiu os Prémios ULisboa - redeSAÚDE 2025 para distinguir os melhores trabalhos de doutoramento e de mestrado realiza...
www.ulisboa.pt
December 29, 2025 at 1:02 PM
Depois de anos de muito trabalho, tive a honra de ser premiada com Melhor Trabalho de PhD na ULisboa. 🏅
Agradeço aos meus orientadores João Lacerda, Rita Azevedo e Maria Soares, aos voluntários, ao JLacerda Lab, à FMUL, e à @gimmfoundation.bsky.social.
Em breve, a defesa para fechar este ciclo! 👩🔬
Agradeço aos meus orientadores João Lacerda, Rita Azevedo e Maria Soares, aos voluntários, ao JLacerda Lab, à FMUL, e à @gimmfoundation.bsky.social.
Em breve, a defesa para fechar este ciclo! 👩🔬
Reposted by GIMM Institute
@EMBO Practical Course
Pipetting scRNA-seq data into computational cells
18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social
Registration open!
Pipetting scRNA-seq data into computational cells
18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social
Registration open!
Pipetting scRNA-seq data into computational cells
Single-cell transcriptomics is transforming biology, uncovering hidden cell states, dynamic transitions, and intricate interactions across systems from immunity to cancer. Yet as these technologies s…
meetings.embo.org
November 23, 2025 at 11:37 AM
@EMBO Practical Course
Pipetting scRNA-seq data into computational cells
18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social
Registration open!
Pipetting scRNA-seq data into computational cells
18 – 23 May 2026 | Oeiras/Lisbon, Portugal @gimmfoundation.bsky.social
Registration open!
Reposted by GIMM Institute
🧑🔬🏆Joe Paton & @minuttilab.bsky.social from @champalimaudf.bsky.social and 7 other PIs from @gimmfoundation.bsky.social, @ucoimbra.bsky.social and @i3suporto.bsky.social have won #CaixaResearch funding 👏
👉 www.fchampalimaud.org/news/caixare...
@caixaresearch.bsky.social
👉 www.fchampalimaud.org/news/caixare...
@caixaresearch.bsky.social
Concurso CaixaResearch de Investigação em Saúde Distingue Investigadores da Fundação Champalimaud e da Fundação GIMM | Champalimaud Foundation
Quatro Investigadores Principais de duas instituições – a Fundação Champalimaud (FC) e a Fundação GIMM (GIMM) – receberam financiamento do Concurso CaixaResearch de Investigação em Saúde para o estudo...
www.fchampalimaud.org
November 20, 2025 at 6:07 PM
🧑🔬🏆Joe Paton & @minuttilab.bsky.social from @champalimaudf.bsky.social and 7 other PIs from @gimmfoundation.bsky.social, @ucoimbra.bsky.social and @i3suporto.bsky.social have won #CaixaResearch funding 👏
👉 www.fchampalimaud.org/news/caixare...
@caixaresearch.bsky.social
👉 www.fchampalimaud.org/news/caixare...
@caixaresearch.bsky.social
Reposted by GIMM Institute
The lack of specific targets in many tumours ⬇️ the effectiveness of immunotherapies.
With a #HealthResearch grant ➕ FCT João Lacerda (@gimmfoundation.bsky.social) is developing CAR-T cells that target a molecule found almost exclusively in tumours to improve therapies.
https://tinyurl.com/ykbcmcjv
With a #HealthResearch grant ➕ FCT João Lacerda (@gimmfoundation.bsky.social) is developing CAR-T cells that target a molecule found almost exclusively in tumours to improve therapies.
https://tinyurl.com/ykbcmcjv
November 20, 2025 at 10:45 AM
The lack of specific targets in many tumours ⬇️ the effectiveness of immunotherapies.
With a #HealthResearch grant ➕ FCT João Lacerda (@gimmfoundation.bsky.social) is developing CAR-T cells that target a molecule found almost exclusively in tumours to improve therapies.
https://tinyurl.com/ykbcmcjv
With a #HealthResearch grant ➕ FCT João Lacerda (@gimmfoundation.bsky.social) is developing CAR-T cells that target a molecule found almost exclusively in tumours to improve therapies.
https://tinyurl.com/ykbcmcjv
Reposted by GIMM Institute
Damage to telomeres, the ends of chromosomes, can initiate cancerous processes.
With a #HealthResearch grant, Claus Maria Azzalin (@gimmfoundation.bsky.social) is studying the role played by TERRA RNA in telomere repair, which could improve our understanding of cancer.
https://tinyurl.com/yjh7j59c
With a #HealthResearch grant, Claus Maria Azzalin (@gimmfoundation.bsky.social) is studying the role played by TERRA RNA in telomere repair, which could improve our understanding of cancer.
https://tinyurl.com/yjh7j59c
November 20, 2025 at 9:58 AM
Damage to telomeres, the ends of chromosomes, can initiate cancerous processes.
With a #HealthResearch grant, Claus Maria Azzalin (@gimmfoundation.bsky.social) is studying the role played by TERRA RNA in telomere repair, which could improve our understanding of cancer.
https://tinyurl.com/yjh7j59c
With a #HealthResearch grant, Claus Maria Azzalin (@gimmfoundation.bsky.social) is studying the role played by TERRA RNA in telomere repair, which could improve our understanding of cancer.
https://tinyurl.com/yjh7j59c
Reposted by GIMM Institute
Front row view of our Maria smoothly presenting her MSc dissertation work on the isoform-specific impact of mutations in CDKN2A in cancer at the Oncobiology Club @gimmfoundation.bsky.social. 💻🧬👏
November 19, 2025 at 3:27 PM
Front row view of our Maria smoothly presenting her MSc dissertation work on the isoform-specific impact of mutations in CDKN2A in cancer at the Oncobiology Club @gimmfoundation.bsky.social. 💻🧬👏
Reposted by GIMM Institute
Podcast com Isabel Gordo, Group Leader no Gulbenkian Institute for Molecular Medicine (@gimmfoundation.bsky.social):
"Como é que um medicamento mata bactérias?"
YouTube: youtu.be/wRyYYa2D5i0
Spotify: open.spotify.com/episode/1AqQ...
"Como é que um medicamento mata bactérias?"
YouTube: youtu.be/wRyYYa2D5i0
Spotify: open.spotify.com/episode/1AqQ...
Ep 4: Como é que um medicamento mata bactérias? (com Isabel Gordo)
YouTube video by GIMM Gulbenkian Institute for Molecular Medicine
youtu.be
November 19, 2025 at 11:27 AM
Podcast com Isabel Gordo, Group Leader no Gulbenkian Institute for Molecular Medicine (@gimmfoundation.bsky.social):
"Como é que um medicamento mata bactérias?"
YouTube: youtu.be/wRyYYa2D5i0
Spotify: open.spotify.com/episode/1AqQ...
"Como é que um medicamento mata bactérias?"
YouTube: youtu.be/wRyYYa2D5i0
Spotify: open.spotify.com/episode/1AqQ...
Reposted by GIMM Institute
EU-LIFE Strategy Meeting 2025 wrapped up in #Basel with strong support, constructive exchanges and a very positive atmosphere.
A big thanks to the @fmiscience.bsky.social team for fostering a welcoming environment for productive, forward-looking discussions!
Read more 🔗 eu-life.eu/newsroom/new...
A big thanks to the @fmiscience.bsky.social team for fostering a welcoming environment for productive, forward-looking discussions!
Read more 🔗 eu-life.eu/newsroom/new...
November 20, 2025 at 9:20 AM
EU-LIFE Strategy Meeting 2025 wrapped up in #Basel with strong support, constructive exchanges and a very positive atmosphere.
A big thanks to the @fmiscience.bsky.social team for fostering a welcoming environment for productive, forward-looking discussions!
Read more 🔗 eu-life.eu/newsroom/new...
A big thanks to the @fmiscience.bsky.social team for fostering a welcoming environment for productive, forward-looking discussions!
Read more 🔗 eu-life.eu/newsroom/new...
Reposted by GIMM Institute
🧵 Thrilled to share our new work in @embojournal! Over a century after Metchnikoff recognized macrophages as central to organismal homeostasis, we reveal how they act as metabolic guardians through an unexpected mechanism.
www.embopress.org/doi/full/10....
(1/9)
www.embopress.org/doi/full/10....
(1/9)
Homeostatic control of energy metabolism by monocyte-derived macrophages | The EMBO Journal
imageimageMacrophages play critical roles in the homeostatic control systems that maintain vital
parameters within physiological ranges. This study characterizes how mouse monocyte-derived
macrophages...
www.embopress.org
November 19, 2025 at 2:11 PM
🧵 Thrilled to share our new work in @embojournal! Over a century after Metchnikoff recognized macrophages as central to organismal homeostasis, we reveal how they act as metabolic guardians through an unexpected mechanism.
www.embopress.org/doi/full/10....
(1/9)
www.embopress.org/doi/full/10....
(1/9)
Reposted by GIMM Institute
Nice to meet the representatives of the Kochard Foundation @gimmfoundation.bsky.social and spend the afternoon talking about T cells and mucosal immunology, shared interests and potential collaborative projects.
November 11, 2025 at 11:37 AM
Nice to meet the representatives of the Kochard Foundation @gimmfoundation.bsky.social and spend the afternoon talking about T cells and mucosal immunology, shared interests and potential collaborative projects.
Reposted by GIMM Institute
We also visited Isabel Gordo's lab at @gimmfoundation.bsky.social (Oeiras) and ran into a familiar face, @martalourenco21.bsky.social former PhD candidate at our lab
November 11, 2025 at 11:38 AM
We also visited Isabel Gordo's lab at @gimmfoundation.bsky.social (Oeiras) and ran into a familiar face, @martalourenco21.bsky.social former PhD candidate at our lab
Reposted by GIMM Institute
This picture was taken right before The Boss' presentation at @gimmfoundation.bsky.social
We initially thought people were just a bit shy but, as it turned out, we were participating in the mandatory drills due to high seismic activity in the area 🤔
Safety first!!
We initially thought people were just a bit shy but, as it turned out, we were participating in the mandatory drills due to high seismic activity in the area 🤔
Safety first!!
November 11, 2025 at 1:31 PM
This picture was taken right before The Boss' presentation at @gimmfoundation.bsky.social
We initially thought people were just a bit shy but, as it turned out, we were participating in the mandatory drills due to high seismic activity in the area 🤔
Safety first!!
We initially thought people were just a bit shy but, as it turned out, we were participating in the mandatory drills due to high seismic activity in the area 🤔
Safety first!!
Reposted by GIMM Institute
Now published on @plos.org Computational Biology!
Same findings as the preprint, with improved analyses suggested by reviewers!
Check it out and let us know how RepliFlow works for you!
journals.plos.org/ploscompbiol...
Same findings as the preprint, with improved analyses suggested by reviewers!
Check it out and let us know how RepliFlow works for you!
journals.plos.org/ploscompbiol...
October 27, 2025 at 6:09 PM
Now published on @plos.org Computational Biology!
Same findings as the preprint, with improved analyses suggested by reviewers!
Check it out and let us know how RepliFlow works for you!
journals.plos.org/ploscompbiol...
Same findings as the preprint, with improved analyses suggested by reviewers!
Check it out and let us know how RepliFlow works for you!
journals.plos.org/ploscompbiol...
Reposted by GIMM Institute
What a pleasure visiting @gimmfoundation.bsky.social in Lisboa -huge thanks to Leonor Saúde for the warm hospitality! Loved exchanging ideas w students, postdocs & faculty about all things #devbio & #regeneration, and meeting old friends in a place that always inspired my curiosity -until next time!
November 4, 2025 at 11:37 AM
What a pleasure visiting @gimmfoundation.bsky.social in Lisboa -huge thanks to Leonor Saúde for the warm hospitality! Loved exchanging ideas w students, postdocs & faculty about all things #devbio & #regeneration, and meeting old friends in a place that always inspired my curiosity -until next time!
Reposted by GIMM Institute
🔬 Community Workshop #1: "Intro to Instrumentation QC in Light Microscopy"
🔹 Learn to monitor laser power
🔹 Record & inspect PSFs
🔹 Analyze data using FIJI + MetroloJ_QC
👩🔬Facilitators from @gimmfoundation.bsky.social, @crg.eu & Nova Medical School (NMS).
Let’s build better #microscopy!
#SPAOM2025
🔹 Learn to monitor laser power
🔹 Record & inspect PSFs
🔹 Analyze data using FIJI + MetroloJ_QC
👩🔬Facilitators from @gimmfoundation.bsky.social, @crg.eu & Nova Medical School (NMS).
Let’s build better #microscopy!
#SPAOM2025
October 22, 2025 at 1:48 PM
🔬 Community Workshop #1: "Intro to Instrumentation QC in Light Microscopy"
🔹 Learn to monitor laser power
🔹 Record & inspect PSFs
🔹 Analyze data using FIJI + MetroloJ_QC
👩🔬Facilitators from @gimmfoundation.bsky.social, @crg.eu & Nova Medical School (NMS).
Let’s build better #microscopy!
#SPAOM2025
🔹 Learn to monitor laser power
🔹 Record & inspect PSFs
🔹 Analyze data using FIJI + MetroloJ_QC
👩🔬Facilitators from @gimmfoundation.bsky.social, @crg.eu & Nova Medical School (NMS).
Let’s build better #microscopy!
#SPAOM2025
Reposted by GIMM Institute
Next, Leonor Saude, from @gimmfoundation.bsky.social, talked about her work using zebrafish and the evolutionary comparisons with mice to pursue spinal cord regeneration in mammals.
October 12, 2025 at 2:08 PM
Next, Leonor Saude, from @gimmfoundation.bsky.social, talked about her work using zebrafish and the evolutionary comparisons with mice to pursue spinal cord regeneration in mammals.
Reposted by GIMM Institute
Then, it was the turn of Nuno Morais ( @nmoraislab.bsky.social ), from GIMM ( @gimmfoundation.bsky.social ) and coordinator of @biomics-twinning.bsky.social , telling us about a cool project on CDKN2A.
October 12, 2025 at 1:48 PM
Then, it was the turn of Nuno Morais ( @nmoraislab.bsky.social ), from GIMM ( @gimmfoundation.bsky.social ) and coordinator of @biomics-twinning.bsky.social , telling us about a cool project on CDKN2A.
Reposted by GIMM Institute
Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...
Cracking organisms’ energy code
Researchers define rules governing how growing microorganisms use energy efficiently
www.mpi-cbg.de
October 7, 2025 at 9:31 AM
Jonathan Rodenfels @mpi-cbg.de, Pablo Sartori @gimmfoundation.bsky.social, and Tommaso Cossetto identified two thermodynamic rules governing the growth and energy utilization of single-celled organisms. Publication in @nature.com Communications. www.mpi-cbg.de/news-outreac...