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Juan Manuel Gomez Elliff

@gomezjm-devmech.bsky.social

160 followers 350 following 39 posts

Mechanobiology. In Job Market 🕵️‍♂️. Brillouin🔬advocate. Senior postdoc@Prevedel Lab-EMBL Heidelberg. Alumni Maria Leptin (EMBL) & Nick Brown (Gurdon Institute). https://orcid.org/0000-0002-3041-2503

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Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · Jul 15

🥁 New article 📢: #Mechanobiology of #development during #Drosophila #gastrulation using #Brillouin microscopy, now in @natcomms.nature.com : rdcu.be/ev6ZX
Collab. w/ @Prevedel_Lab @embl.org , Maria Leptin @marialep.bsky.social, @abhisha-thayambath.bsky.social, Julio Belmonte @ncstate.bsky.social

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Reposted by Juan Manuel Gomez Elliff

Manuel Thery @manuelthery.bsky.social · 1d

What would happen if cells would express more molecular motors ?
They would break all microtubules 😱
As shown by recent great work from @kjverhey1.bsky.social

rupress.org/jcb/article-...

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Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 13h

John’s legacy will continue to inspire. As a developmental biologist, I was profoundly touched by his intellect, generosity, and vision. The Gurdon Institute embodies his belief in creativity and excellence in science. That is his torch that we will carry forward.

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 13h

2) The secret of his chalk drawings: John was renowned for his ability to draw morphogenetic events, e.g. gastrulation, in real-time. Once he 'confessed' that he drew them in green chalk before the class starts, and during the lecture, he followed the trace.

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Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 13h

Two beautiful memories stand out:
1) John, The Mad Hatter: Seeing Sir John dressed as the Mad Hatter at the Gurdon Institute Christmas party was unexpected and perfect at the same time. He was radiant with joy, and his costume was absolutely perfect, it suited his playful spirit wonderfully.

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 13h

John was always approachable, whether for scientific or political discussions. He was a constant presence at Institute seminars, and there was invariably a key, incisive question coming from him.

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 13h

He created the Gurdon Institute, a top scientific centre at the heart of Cambridge, both geographically and intellectually. My time at the Gurdon Institute began shortly after he received the Nobel Prize.

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 13h

John Gurdon will be deeply missed: a sharp mind, a warm and witty sense of humour, and a visionary who shaped our understanding of developmental biology. I admired his intelligence, envied his prominent hair🙂. Left photo, in archives of Nobel, taken by John Overton, photographer and our lab manager.

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MRC Laboratory of Molecular Biology @mrclmb.bsky.social · 16h

John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died.
Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology.
More: www2.mrc-lmb.cam.ac.uk/john-gurdon-...
#LMBNews

Black and white portrait of John Gurdon, 1971

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Reposted by Juan Manuel Gomez Elliff

The New York Times @nytimes.com · 16h

Dr. John Gurdon, a British biologist and Nobel laureate who in the early 1960s introduced a paradigm-shifting method of cell manipulation that led to the world’s first cloning of a large mammal, a sheep named Dolly, died on Tuesday at 92.

John B. Gurdon, 92, Dies; Nobelist Paved Way for Cloning of Animals

His work in the manipulation of cells laid the foundation for stem cell biology and regenerative medicine and led to the first cloned large mammal, a sheep named Dolly.

nyti.ms

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Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 14h

And of course, a legacy of Science, and great institute.

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 14h

Couldn t be said better. Great scientist, noble person, great mad hatter at Gurdon parties, best gastrulation drawings on greenboards already pre drawn in disguise by him. 🙂

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Reposted by Juan Manuel Gomez Elliff

Barriga Lab @eliasbarrigalab.bsky.social · 15d

Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!

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Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 21d

indeed, so one should start writing early enough

Reposted by Juan Manuel Gomez Elliff

Mechanobiology Institute @mbisg.bsky.social · 26d

We would like to once again, thank all the sponsors for their generosity in supporting #MBIMPG2025 @leicamicrosystems.bsky.social @nikoninst.bsky.social @oxfordinstruments.bsky.social, Optics11Life, BGI, Office of Naval Research Global and Paeonia Foundation.

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Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 27d

Order or disorder? 🙂

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · 27d

Congratulations Ale!!!!! 🎉🎉🎉

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · Sep 6

Great work from two great scientists that happen to be my friends too, so I am double happy, for Developmental Biology and for them and their groups!

Congratulations!!!!!! 🎉🎉Yu Chiun Wang and Steffen Lemke!!!!! @yuchiunwang.bsky.social

Yu-Chiun Wang @yuchiunwang.bsky.social · Sep 4

Tissue 'tectonic' collision is detrimental, but flies found two distinct solutions! Gratifying and grateful to be included in this collective effort, w/ Steffen Lemke, to crack the (or 'a') code of #cephalicfurrow, now out in @nature.com, all with @paveltomancak.bsky.social at the helm. (1/9)

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · Sep 6

Great work, congratulations to all co-authors of this beautiful work! @paveltomancak.bsky.social

#Mechano-evo-devo
#Morphogenesis
#Mechanobiology

paveltomancak.bsky.social @paveltomancak.bsky.social · Sep 4

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

Reposted by Juan Manuel Gomez Elliff

Tessmar-Raible Labs @tessmarraiblelabs.bsky.social · Jul 15

Interested to use cutting-edge imaging approaches to study the #evolution of #heart #morphogenesis? The Panfilio lab has a fully funded 3-year #postdoc offer in the framework of a new international #HFSP project: tinyurl.com/4p28nzs7 For details and applications, see tinyurl.com/ApplyHeartPo...

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Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · Jul 17

Thanks for the really nice post @ewanbirney.bsky.social 🙂.

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · Jul 16

Gracias @yosoyden.bsky.social 🙂🙂

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · Jul 15

Thank you very much!!!! Best thing in the world to see a colleague excited about our work!

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · Jul 15

Thank you very much Pavel, looking forward to your opinion about it! 🙂🙏

Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · Jul 15

Thanks to everyone who contributed: Carlo for BM, Julio & Abhisha @ncstate.bsky.social for the physical model, @marialep.bsky.social for your feedback and Robert @prevedel-lab.bsky.social for your supervision and allowing me to work freely.

BTW: I am looking for GL positions! 👨‍🏫 😃

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Juan Manuel Gomez Elliff @gomezjm-devmech.bsky.social · Jul 15

This is the second simulation, with contractility and stiffness increasing over time (the latter derived from what we learnt using Brillouin microscopy):

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