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Parthive Patel @gutstresslab.bsky.social · 2d

Congratulations @bardinlab.bsky.social !

Reposted by Parthive Patel

Bardin Lab @bardinlab.bsky.social · 2d

The PhD work of @bboumard.bsky.social officially out in print! Happy to share this issue with our downstairs colleagues in the BDD @frelab.bsky.social @robinjournot.bsky.social

www.cell.com/developmenta...

Cell-type-specific nucleotide sharing through gap junctions impacts sensitivity to replication stress in Drosophila

Boumard et al. demonstrate gap-junction-dependent tissue-scale nucleotide sharing, which impacts cellular sensitivity to perturbation of nucleotide homeostasis and replication stress. Drosophila wing ...

www.cell.com

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Reposted by Parthive Patel

Alex Gould Lab @alexgouldlab.bsky.social · 5d

Passionate about doing a PhD on metabolism in neural stem cells and their niche? The call just opened for applications for a PhD position in our lab @crick.ac.uk in London. Please repost.
tinyurl.com/ysnkdrmw

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Parthive Patel @gutstresslab.bsky.social · 6d

Thank you for hosting me! It was a lovely visit.

Development, Regeneration and Neurophysiology @drn-sheffield.bsky.social · 8d

Today’s speaker in our DRN external seminar series is Dr Parthive Patel @gutstresslab.bsky.social (University of Bristol)

Sponsored by the Physiological Society @physoc.bsky.social

Host: Kyra Campbell
@kyracampbelllab.bsky.social

All welcome!

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Parthive Patel @gutstresslab.bsky.social · 17d

Congratulations, Liz and @pujabiswas.bsky.social !

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Reposted by Parthive Patel

Mark Peifer (He, him) @peiferlabunc.bsky.social · Aug 23

The community of Drosophila researchers is amazing, mutually supportive and collaborative. Right now a key resource for our community, @flybase.bsky.social , is threatened by the cancellation of its NIH grant and is seeking community help in raising short term funds 1/n 🧪 please share

Dear Fly Community,

In May 2025, the NIH terminated all grant funding to Harvard University, including the NHGRI grant that supported FlyBase. This grant also funded FlyBase teams at Indiana University (IU) and the University of Cambridge (UK), and as a result, their subawards were also canceled.

The Cambridge team has secured support for one to two years through generous donations from the European fly community, emergency funding from the Wellcome Trust, and support from the University of Cambridge. At IU, funding has been secured for one year thanks to reserve funds from Thom Kaufman and a supplement from ORIP/NIH to the Bloomington Drosophila Stock Center (BDSC).

Unfortunately, the situation at Harvard is far more critical. Harvard University had supported FlyBase staff since May but recently denied a request for extended bridge funding. As a result, all eight employees (four full-time and four part-time) were abruptly laid off, with termination dates ranging from August to mid-October depending on their positions. In addition, our curator at the University of New Mexico will leave her position at the end of August. This decision came as a shock, and we are urgently pursuing all possible funding options.

To put the need into perspective: although FlyBase is free to use, it is not free to make. It takes large teams of people and millions of dollars a year to create FlyBase to support fly research (the last NHGRI grant supported us with more than 2 million USD per annum).

To help sustain FlyBase operations, we have been reaching out to you to ask for your support. We have set up a donation site in Cambridge, UK, to which European labs have and can continue to contribute, and a new donation site at IU to which labs in the US and the rest of the world can contribute. We urge researchers to work with their grant administrators to contribute to FlyBase via these sites if at all possible, as more of the money will go to FlyBase. However, we appreciate that some fu…

https://wiki.flybase.org/wiki/FlyBase:Contribute_to_FlyBase

Our immediate goals are:

1. To maintain core curation activities and keep the FlyBase website online

2. To complete integration with the Alliance of Genome Resources (The Alliance).

Integration with the Alliance is essential for FlyBase’s long-term sustainability. For nearly a decade, NHGRI/NIH has supported the unification of Model Organism Databases (MODs) into the Alliance, which we aim to achieve by 2028. Therefore, securing bridge funding to sustain FlyBase over the next three years is crucial for successful integration and the long-term access to FlyBase data.

At present, our remaining funds will allow us to keep the FlyBase website online for approximately one more year. Beyond that, its future is uncertain unless new funding is secured. We will, of course, continue pursuing additional grant opportunities as they arise.

Given the uncertainty of future NIH or alternative funding sources, we are relying on the Fly community for support. Your contributions will directly help us retain the staff needed to complete this transition and to secure ongoing fly data curation into the Alliance beyond 2028.

We at FlyBase are incredibly grateful for the outpouring of support from the community during this challenging time. Your encouragement has strengthened our resolve and underscores how vital this resource remains to Drosophila research worldwide.

Sincerely,
The FlyBase Team

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Reposted by Parthive Patel

Elizabeth Rideout @ejrideout.bsky.social · Aug 22

I watched the video and donated - it was super easy! Please donate if you’re able, and help spread the word so that we can keep this essential resource going.

FlyBase @flybase.bsky.social · Aug 15

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

FlyBase:Contribute to FlyBase - FlyBase Wiki

wiki.flybase.org

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Reposted by Parthive Patel

Mark A. Hanson @hansonmark.bsky.social · Aug 14

A reminder you/your lab can support FlyBase at Cambridge through the following link. Every bit helps. Please share if you yourself can't donate.

www.philanthropy.cam.ac.uk/give-to-camb...

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Parthive Patel @gutstresslab.bsky.social · Aug 3

@bortz-virology.bsky.social

Reposted by Parthive Patel

Amoyel lab @amoyellab.bsky.social · Jul 27

Lovely work by @martinestermann.bsky.social and colleagues from the Capel lab! Together with our recent work (www.biorxiv.org/content/10.1...), this really makes a strong case that lactate is crucial to supporting male germ cells in vivo - from flies to mammals.

bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · Jul 27

Glycogen metabolism in mouse embryonic Sertoli cells sustains the germ line through the lactate shuttle https://www.biorxiv.org/content/10.1101/2025.07.23.666216v1

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Reposted by Parthive Patel

corderolab.bsky.social @corderolab.bsky.social · Jul 21

Very happy and proud to share the latest work from our lab.
Neuroendocrine control of intestinal regeneration through the vascular niche.
www.sciencedirect.com/science/arti...

Neuroendocrine control of intestinal regeneration through the vascular niche in Drosophila

Robust and controlled intestinal regeneration involves reciprocal interactions between the intestinal epithelium and its microenvironment. Here, we id…

www.sciencedirect.com

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Reposted by Parthive Patel

The EMBO Journal @embojournal.org · Jul 22

How does nutrient-responsive #mTORC1 sense the key amino acid #glutamine?
Gianluca Figlia, Aurelio Teleman et al @telemanlab.bsky.social identify a combination of GCN2-dependent processes triggered by secondary depletion of asparagine in glutamine-starved cells
www.embopress.org/doi/full/10....

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Reposted by Parthive Patel

Irene Miguel-Aliaga @irenemiguel-aliaga.bsky.social · Mar 19

Epic effort led by Tomo Ameku in the lab, with contributions from the labs of Nick Bellono, Vassilis Pachnis, @francoisleulier.bsky.social, @schwarzergnoto.bsky.social, @priscaliberali.bsky.social, ‪@coxlabkcl.bsky.social,‬ @priscaliberali.bsky.social and Maria Rodriguez-Colman

Irene Miguel-Aliaga @irenemiguel-aliaga.bsky.social · Mar 19

Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: www.cell.com/cell/fulltex...

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Reposted by Parthive Patel

Alex Gould Lab @alexgouldlab.bsky.social · Jun 4

Calling all European #Drosophila labs. Time for all of us, that are able, to step up to support FlyBase during this funding crisis.

FlyBase @flybase.bsky.social · Jun 3

We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.

Mark A. Hanson @hansonmark.bsky.social · Jun 3

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯

Any lab using @flybase.bsky.social please donate using the link in post below.

This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

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Reposted by Parthive Patel

European Drosophila Society @fly-eds.bsky.social · Jun 4

#Drosophila @flybase.bsky.social requires emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to #FlyBase, and in the worst case scenario access to the website will also be lost". Please help if you can!

FlyBase @flybase.bsky.social · Jun 3

We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.

Mark A. Hanson @hansonmark.bsky.social · Jun 3

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯

Any lab using @flybase.bsky.social please donate using the link in post below.

This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

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Reposted by Parthive Patel

Katja Röper @katjaroeper.bsky.social · Jun 4

European Fly PIs: please respond to the email we sent out yesterday and help save FlyBase!

FlyBase @flybase.bsky.social · Jun 3

We currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.

Mark A. Hanson @hansonmark.bsky.social · Jun 3

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯

Any lab using @flybase.bsky.social please donate using the link in post below.

This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

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