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Maik Bischoff @maikbischoff.bsky.social · 14d

1/12 A very special moment for me! 🎉

My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes.

rupress.org/jcb/article/...

#cellbio #devbio #science

🧵for details

Cartoon of a speculative heterogenous cell population performing mesenchymal collective cell migration.

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Journal of Cell Biology @jcb.org · 15d

New perspective by @maikbischoff.bsky.social & @mayorlab.bsky.social about how mesenchymal cells use contact-dependent rules to generate swarm-like behaviors, patterns & organ forms. rupress.org/jcb/article/...

#CellBio #CellMigration #Morphogenesis #Development #Science

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Angelman Syndrome Foundation @angelmanfoundation.bsky.social · Jun 26

We’re excited to announce the launch of our new website at angelman.org! 🎉 Our updated site features easy navigation and filters that help you find the resources, clinics, research, and support you need on any device. Check it out!➡️ angelman.org

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Joe McKellar @viroscope.bsky.social · Jun 27

A Boa Constrictor brain-derived cell expressing a viral glycoprotein (magenta) and stained for actin (yellow) and DNA (white).

#FluorescenceFriday

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Ina Klockner 🧬👩‍🔬🔬 @inaklockner.bsky.social · Jun 27

Added!

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Ina Klockner 🧬👩‍🔬🔬 @inaklockner.bsky.social · Jun 27

Sure! I will add you ASAP 🙂

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Maik Bischoff @maikbischoff.bsky.social · Jun 18

FINALLY out in #Science Advances! 🎉
3 years of hard work, a fantastic team — and I’m proud to be first and co-corresponding author!

It's about Plexin signaling driving collective cell migration & organ sculpting. Check out the videos 😀

www.science.org/doi/10.1126/...

#DevBio #CellBio #Microscopy

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Marco A. Maximo Prado @maximoprado.bsky.social · Jun 13

For #fluorescencefriday the Mesoscopic Integrated NeuroImaging Data (MIND) platform @westernu.bsky.social presents abeta plaques and blood vessels in the 🧠 of our ApoE4 mouse model of AD. 🧪 #clearing #lightsheet 🔬 Courtesy of Arash Salahinejad, Luke Smolders and @shahrzadbahrampour.bsky.social

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Ina Klockner 🧬👩‍🔬🔬 @inaklockner.bsky.social · Jun 6

Stunning images!

Mathieu Preußner @mathpreu.bsky.social · Jun 6

1)
Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood.

#zebrafish #gills #microscopy

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Mathieu Preußner @mathpreu.bsky.social · Jun 6

1)
Branching morphogenesis is fundamental to animal development, shaping complex organs like lungs, kidneys, and vascular networks. Gills are another highly branched organ. Yet, the developmental processes behind gill formation in zebrafish remain poorly understood.

#zebrafish #gills #microscopy

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Mathieu Preußner @mathpreu.bsky.social · Apr 11

Gills just wanna have #FluorescenceFriday 🎵

Phalloidin reveals the beauty of the filament's distal tip in cleared gills of adult 🦓🐟

#microscopy #devbio #sciart

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Angelman Syndrome Foundation @angelmanfoundation.bsky.social · Feb 10

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Maik Bischoff @maikbischoff.bsky.social · Mar 28

I know, it's a bit late for #FluorescenceFriday but I want to share my new banner :D

#cellmigration #cellbio #devbio #sciart #microcosm #science

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Tamas Nagy @tamasnagy.com · Mar 22

I begrudgingly admit that actin is pretty cool 🤩

🎥 Primary mouse myotubes labeled with Lifeact-mScarlet-I3 (cyan) and H2B-mStayGreen (red). #FluorescenceFriday

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Maik Bischoff @maikbischoff.bsky.social · Mar 11

2/4 I chose this picture because I am interested in an old question:

How do fly testes obtain their specific shape?

In my previous research I learned that muscle precursors shape it, using collective cell migration and alignement to achieve the pattern visible in this picture.

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Rami Major, Ph.D. 🧬✨ @doe-rami.bsky.social · Mar 8

Stand up for science Raleigh!! Let’s keep this energy going!!

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Mathieu Preußner @mathpreu.bsky.social · Feb 28

Mesonephric glomeruli of #zebrafish for #FluorescenceFriday 🔬
kdrl-mCherry nicely reveals the capillary tuft of the glomerulus.

The zebrafish kidney stops developing at the mesonephros stage! It serves as their main kidney structure, and they don't develop a metanephros like humans do.

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Maik Bischoff @maikbischoff.bsky.social · Feb 28

For today's #fluorescencefriday I have a riddle 😊. Can anyone who is knowledgeable in #Drosophila #neuroscience tell my what these are? I honestly don't know! Overview picture in the comments-they are from the brain🧠🪰. The marker is lifeact::GFP, depth-coded...
#sciart #microscopy #cellbio #cellfy🔬

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Maik Bischoff @maikbischoff.bsky.social · Feb 7

An ancient unpublished picture from my PhD
#FluorescenceFriday!

Drosophila sperm pump depth-coded
with muscles (phalloidin=cyan/green) + Dapi (yellow/red).

Not confocal but an old Zeiss Apotome - which is still an awesome scope! #sciart #microscopy #bioart #sciart #microscopyart #cellbio #devbio

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Maik Bischoff @maikbischoff.bsky.social · Jan 30

Wow! We got the cover! #MBOC #ASCB #CellBio
So proud of #TeamTestis. Screening <270 lines for shape defects was a huge team effort!

I created this collage from the team’s images from the past 2 years! Depth-color-coded with Fiji. Inspired by late 19th century lithographic animal illustrations.

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Mathieu Preußner @mathpreu.bsky.social · Dec 20

🔬My first try on #FluorescenceFriday
Nice detail of a tissue-cleared kidney from neonatal mice.
-GFP is expressed in podocytes and pericytes.
-CD31 antibody highlights the branched blood vessels and glomeruli in red

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Zhixing Chen @zhixingchen2.bsky.social · Dec 19

How proximal is proximity labeling❓ Using DNA nanorulers we found that TurboID/BioID are largely contact labeling, while APEX2 also bears a major contact labeling pathway in parallel with diffusive labeling.
www.biorxiv.org/content/10.1...

Special thanks to @aliceyting.bsky.social for discussions

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Frank Schnorrer @frankschnorrer.bsky.social · Dec 19

Muscles growth by sarcomere divisions - how your muscles add new sarcomeres during developmental growth: they divide! Cool collaboration @friedrich-group.bsky.social @raunser-lab.bsky.social @Dirk Görlich @univ-amu.fr @cnrs.bsky.social sciencecast.org/casts/aspy9l... www.biorxiv.org/content/10.1...

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CRISPRGuru @crisprguru.bsky.social · Dec 3

For those interested in "Genome editing and CRISPR technologies":

(if you are new here at Bluesky), here are the two starter packs...

bsky.app/starter-pack...

bsky.app/starter-pack...

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Maik Bischoff @maikbischoff.bsky.social · Dec 12

Excited to give my 1st talk on an #ASCB meeting about collective #cellmigration in #Drosophila! #cellbio2024
12/16 4pm Room 33B, more info below👇!
Next, I'll post about our 2 posters!🪰

Thank you @allysonsgro.bsky.social & Daniel Cohen for this opportunity!
#cellbio #devbio @ascbiology.bsky.social

The title of my talk is Plexin/Semaphorn Signaling Orchestrates Collective Cell Migration. It will be on 12/16 at 4PM in Room 33B!

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