Harini Iyer
@iyerharini.bsky.social
840 followers
400 following
6 posts
Assistant Professor at Rice Biosciences. Lover of all things microglia, lysosomes, and zebrafish. And dogs, of course! https://iyerlaboratory.org/
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Reposted by Harini Iyer
Reposted by Harini Iyer
Reposted by Harini Iyer
Jonathan Pritchard
@jkpritch.bsky.social
· Jan 26
Causal modeling of gene effects from regulators to programs to traits: integration of genetic associations and Perturb-seq
Genetic association studies provide a unique tool for identifying causal links from genes to human traits and diseases. However, it is challenging to determine the biological mechanisms underlying mos...
www.biorxiv.org
Reposted by Harini Iyer
Ethan Hughes
@ethanhugheslab.bsky.social
· Jan 18
Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function - Nature Communications
Remyelination can restore neural function. Here, the authors characterize the drivers and limits of endogenous remyelination and explore a therapy that rescued remyelination deficits and accelerated n...
www.nature.com
Reposted by Harini Iyer
Martin Kampmann
@kampmann.bsky.social
· Jan 14
CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions
Using a 3D co-culture system of iPSC-derived neurons and glia, termed iAssembloids,
combined with CRISPRi-based screening, Li et al. investigate the effect of glial cells
on neuronal activity and surv...
www.cell.com
Reposted by Harini Iyer
Reposted by Harini Iyer
Reposted by Harini Iyer
Reposted by Harini Iyer
Reposted by Harini Iyer
BrunetLab
@brunetlab.bsky.social
· Dec 18
Spatial transcriptomic clocks reveal cell proximity effects in brain ageing
Nature - A spatially resolved single-cell transcriptomics map of the mouse brain at different ages reveals signatures of ageing, rejuvenation and disease, including ageing effects associated with T...
rdcu.be
Reposted by Harini Iyer
Reposted by Harini Iyer
Reposted by Harini Iyer
Harini Iyer
@iyerharini.bsky.social
· Dec 10
Reposted by Harini Iyer
Reposted by Harini Iyer
Sarah Cohen
@cohenlaboratory.bsky.social
· Nov 11
Reposted by Harini Iyer
Mary Munson
@marymunson4.bsky.social
· Dec 8
Reposted by Harini Iyer
Angelo Iulianella
@aineurolab.bsky.social
· Nov 16
Harini Iyer
@iyerharini.bsky.social
· Dec 8
Reposted by Harini Iyer
Reposted by Harini Iyer