James Zou
@jameszou.bsky.social
2.1K followers 11 following 39 posts
@Stanford Professor. AI for science and medicine.
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jameszou.bsky.social
⚡️Thrilled that #VirtualLab is published in @nature.com! www.nature.com/articles/s41...

We created a team of AI agents to mirror my Stanford lab 🤖. Led by a PI agent, the AI scientists ran their own group meetings and discovered effective binders to new CoVID variants that we validated.
Reposted by James Zou
cellpress.bsky.social
#AI wrote nearly a quarter of corporate press releases in 2024 and the number is likely to keep rising. spkl.io/63324ATfBo

Weixin Liang, @jameszou.bsky.social & colleagues
@cp-patterns.bsky.social
First page of article: "The widespread adoption of large language model-assisted writing across society" published in Patterns
Reposted by James Zou
jonc101.bsky.social
@stanforddeptmed.bsky.social Biomedical Informatics Research Colloquia

“AI Agents to Automate Biomedical Discoveries”
@jameszou.bsky.social James Zou, Ph.D

Thursday, September 25th, 2025
12:00 to 1:00 pm PST

stanford.zoom.us/j/9788759601...

Webinar ID: 978 8759 6012
Webinar Passcode: 420642
James Zou, Ph.D
Reposted by James Zou
andytseng.bsky.social
Fantastic talk by @stanford.edu's @jameszou.bsky.social for the first Innovation Initiative Distinguished Lecture at @whiteheadinstitute.bsky.social. A fascinating look at how to use #AI to build intelligent research teams that can tackle open-ended scientific problems. #WhiteheadInstitute #MIT
jameszou.bsky.social
🧠Can AI agents predict #Alzheimers? Participate in our DREAM challenge agentic track to find out!

We provide unique training + test data for AI agents: snRNA-seq, IHC, stage, etc synapse.org/Synapse:syn6...

Also co-submit your agent paper to agents4science.stanford.edu
Reposted by James Zou
stanfordhai.bsky.social
“Good science happens when we have deep, interdisciplinary collaborations, and often that’s one of the main bottlenecks and challenging parts of research,” said HAI Faculty Affiliate @jameszou.bsky.social who led a study on AI-driven virtual labs: med.stanford.edu/news/all-new...
Researchers create ‘virtual scientists’ to solve complex biological problems
Stanford Medicine researchers created a team of virtual scientists backed by artificial intelligence to help solve problems in their real-world lab.
med.stanford.edu
Reposted by James Zou
ai.nejm.org
NEJM AI @ai.nejm.org · Jul 30
Case Study by Eric Wu, PhD, Kevin Wu, PhD, and James Zou, PhD: Limitations of Learning New and Updated Medical Knowledge with Commercial Fine-Tuning Large Language Models nejm.ai/4nTx1Np

@jameszou.bsky.social #AI #MedSky
Figure 1. An Overview of the Fine-Tuning Case Study. Figure 2. Performance of Fine-Tuned Large Language Models on Each Medical Dataset. Figure 3. Model Performance on MedQA after Updating.
jameszou.bsky.social
⚡️Thrilled that #VirtualLab is published in @nature.com! www.nature.com/articles/s41...

We created a team of AI agents to mirror my Stanford lab 🤖. Led by a PI agent, the AI scientists ran their own group meetings and discovered effective binders to new CoVID variants that we validated.
Reposted by James Zou
erictopol.bsky.social
Who do you call when you need to design novel, potent nanobodies vs a pathogen?
The virtual lab of A.I. agents @nature.com @jameszou.bsky.social @kylewswanson.bsky.social
www.nature.com/articles/s41...
Reposted by James Zou
da-bar.bsky.social
Day 3 of #ISMBECCB2025 started with an excellent talk from @jameszou.bsky.social which presented how AI can form virtual labs to discuss problems, how can AI reanalyse research data to get new biological results, and how we can interpret complex AI predictions 💻🤖
Reposted by James Zou
ai.nejm.org
NEJM AI @ai.nejm.org · Jul 23
Six frontier large language models evaluated on incorporating newly updated medical knowledge through commercial fine-tuning application programming interfaces struggled to generalize updated information, despite modest gains. Learn more: nejm.ai/4nTx1Np

@jameszou.bsky.social
Figure 1. An Overview of the Fine-Tuning Case Study.
jameszou.bsky.social
🏆Thrilled that #CollabLLM won the #ICML2025 Outstanding Paper Award!

We propose a new approach to optimize human-AI collaboration, which is critical for agents. Congratulations to my fantastic co-authors; great job Shirley Wu and Michel Galley driving the project! 👏

Paper: arxiv.org/pdf/2502.00640
Reposted by James Zou
hlzhang109.bsky.social
Introducing EvoLM, a model suite with 100+ decoder-only LMs (1B/4B) trained from scratch, across four training stages —

🟦 Pre-training
🟩 Continued Pre-Training (CPT)
🟨 Supervised Fine-Tuning (SFT)
🟥 Reinforcement Learning (RL)
EvoLM: In Search of Lost Language Model Training Dynamics
Modern language model (LM) training has been divided into multiple stages, making it difficult for downstream developers to evaluate the impact of design choices made at each stage. We present EvoLM, ...
arxiv.org
jameszou.bsky.social
Great job by Sam Alber, Bowen Chen, Alina Isakova, Aaron Wilk!
jameszou.bsky.social
High throughput data are goldmines that we often only scratch the surface. Great for AI to systematically analyze! CellVoyager makes Jupyter notebooks for easy replication
📜https://www.biorxiv.org/content/10.1101/2025.06.03.657517v1
💻https://github.com/zou-group/CellVoyager
jameszou.bsky.social
💡IMO one of the best use of AI Scientist is to reanalyze data to find new insights.

Introducing #CellVoyager: AI Compbio Agent that makes new discoveries by autonomously analyzing papers/data, which we then validate🚀

New findings on aging, Covid, scRNAseq etc. Open source!
Reposted by James Zou
sten.linnarsson.org
Very cool work from James Zou. Link to paper: www.nature.com/articles/s41...
jameszou.bsky.social
Excited that nuclei.io is featured on the cover of Nature BME! AI-clinician collaboration paper rdcu.be/dLgV1
jameszou.bsky.social
Here's the non-paywall version of our #TextGrad paper rdcu.be/efRp4! 📜
Reposted by James Zou
stevenartandi.bsky.social
SCI member @jameszou.bsky.social & others present a method for genAI self-improvement via a new calculus of text. They show TextGrad’s power in optimizing agents, molecules, code, treatments, & more, solving PhD-level problems and enabling impactful #AI development. www.nature.com/articles/s41...