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Sten Linnarsson @sten.linnarsson.org · Aug 16

progress.openai.com

OpenAI Progress

AI has been evolving at an incredible rate. This piece aims to highlight the progress made so far.

progress.openai.com

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Sten Linnarsson @sten.linnarsson.org · Aug 15

A little over two weeks to the deadline! 20 positions, generous startup funding, a great community and fantastic infrastructure. Come join us!

Sten Linnarsson @sten.linnarsson.org · Jun 25

A major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)

Karolinska Institutet @ki.se · Jun 25

Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential.
🔗 All positions: ki.se/en/about-ki/...

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Reposted by Sten Linnarsson

Mark Copelovitch @mcopelov.bsky.social · Jul 28

If you were alive in the 1980s, this is among the most wonderful & truly incredible things you have ever witnessed in your lifetime.

Don't Fret. It Adores You @seed-corn-thoughts.bsky.social · Jul 27

Anyways, AIDS is going to be gone soon, this is a generic with FDA full approval.

The first 100% effective HIV prevention drug is approved and going global

An epidemic that's been sustained for 44 years might finally be quelled, with the milestone approval of the first HIV drug that offers 100% protection with its twice-yearly injections. It's a landmark...

newatlas.com

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Sten Linnarsson @sten.linnarsson.org · Jul 1

”All contracts with Springer Nature are terminated or no longer active. Precious taxpayer dollars should be [sic] not be used on unused subscriptions to junk science.” the NIH spokesperson said. www.nature.com/articles/d41...

Trump team axes contracts with publishing giant Springer Nature

The action comes as high-ranking US officials criticize top journals as ‘woke’ and ‘corrupt’.

www.nature.com

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Reposted by Sten Linnarsson

Pelechano lab @pelechanolab.bsky.social · Jul 1

We're looking for a new Assistant Professor in Experimental Tumor Biology to join us at Karolinska Institutet (MTC) @ki.se .
Generous funding package and part of a 20 Assistant Prof recruitment in a wide range of subject areas.
📅 Deadline: Sep 2nd, 2025
ki.varbi.com/en/what:job/...

Assistant Professor in Experimental Tumor Biology

Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universitie

ki.varbi.com

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Reposted by Sten Linnarsson

Johan Lundstrom @odorjohan.bsky.social · Jun 20

1/3 I spent 10 years running a lab in Philadelphia and then decided to return to Europe and continue in a more family friendly environment. Best decision of my life! You can now do the same by applying to one of these 20 assistant professor positions at Karolinska Institutet ki.se/en/about-ki/...

Early-career researcher — join a global community of excellence

Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. In 2025, KI will recruit outstanding early-career researchers with particularly e...

ki.se

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Reposted by Sten Linnarsson

Björn Högberg @bjornhogberg.bsky.social · Jun 25

Come join our department at the Karolinska Institute! ki.varbi.com/what:job/job...

Assistant Professor in Biomedical Science

Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universities,

ki.varbi.com

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Sten Linnarsson @sten.linnarsson.org · Jun 25

There are no h-index requirements. We will assess your proposal, CV, and the eligibility requirements (e.g. max 7 years after PhD with time allowed for certain activities). The key is to adress an important challenge, with a novel approach, reasonably feasible. But each position has its own profile!

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Gonçalo Castelo-Branco @gocastelobranco.bsky.social · Jun 25

The call just opened!

ki.se/en/about-ki/...

You can apply to several departments simultaneously, check out which depts better fit your profile! Here is the call for our Department of Medical Biochemistry and Biophysics

ki.varbi.com/what:job/job...

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Sten Linnarsson @sten.linnarsson.org · Jun 25

These are the ads from my departments (as dean) but there are many more across the institute: ki.se/en/about-ki/...

KI is recruiting 20 Assistant Professors

Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

ki.se

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Sten Linnarsson @sten.linnarsson.org · Jun 25

The Department of Medical Epidemiology will recruit in epidemiology and biostatistics. Six years, 9 MSEK startup package.

ki.varbi.com/what:job/job...

Assistant Professor in epidemiology or biostatistics at MEB

Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universities,

ki.varbi.com

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Sten Linnarsson @sten.linnarsson.org · Jun 25

The Institute of Environmental Medicine will recruit in, yes, environmental medicine. Six years, 12 MSEK startup package.

ki.varbi.com/se/what:job/...

Assistant Professor in Environmental Medicine

Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universities,

ki.varbi.com

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Sten Linnarsson @sten.linnarsson.org · Jun 25

The Department of Department of Microbiology, Tumor and Cell Biology will recruit in Experimental Tumor Biology. Six years, 12 MSEK startup package.

ki.varbi.com/en/what:job/...

Assistant Professor in Experimental Tumor Biology

Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universitie

ki.varbi.com

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Sten Linnarsson @sten.linnarsson.org · Jun 25

The Department of Physiology and Pharmacology will recruit in ”physiology or medicine of extreme environments”. Six years, 12 MSEK startup package.

ki.varbi.com/se/what:job/...

Assistant Professor in Human physiology or medicine of extreme environments

Assistant Professor in Human physiology or medicine of extreme environments Karolinska Institutet, Department of Physiology and Pharmacology Join a global community of excellence Are you a bold, creat

ki.varbi.com

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Sten Linnarsson @sten.linnarsson.org · Jun 25

The Department of Cell and Molecular Biology will recruit broadly in… cell and molecular biology: ”long-term projects with the prospect of leading to groundbreaking discoveries” Six years, 12 MSEK startup package.

ki.varbi.com/what:job/job...

Assistant Professor in Cell and Molecular Biology

Join a global community of excellence Karolinska Institutet, Department of Cell and Molecular Biology Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Insti

ki.varbi.com

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Sten Linnarsson @sten.linnarsson.org · Jun 25

The Department of Medical Biochemistry and Biophysics (my dept) will recruit broadly in molecular experimental biomedicine: Fundamental human biology, disease and technology development. Six years, 12 MSEK startup package

ki.varbi.com/what:job/job...

Assistant Professor in Biomedical Science

Join a global community of excellence Are you a bold, creative researcher ready to shape the future of medical science? Karolinska Institutet (KI), one of the world’s foremost medical universities,

ki.varbi.com

1

Sten Linnarsson @sten.linnarsson.org · Jun 25

A major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)

Karolinska Institutet @ki.se · Jun 25

Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential.
🔗 All positions: ki.se/en/about-ki/...

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Reposted by Sten Linnarsson

Melanie D. White @melaniedwhite.bsky.social · Jun 20

In these turbulent times, beautiful microscopy always cheers me up 😍. Here's a quail neural tube just doing its thing for #FluorescenceFriday. Imaged by the very talented
@vanderspuy.bsky.social
#devbio 🧪🔬👩‍🔬

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Reposted by Sten Linnarsson

Bruce Levine, Ph.D. 🇺🇦 @bllphd.bsky.social · Jun 19

🚨NEW - In vivo CAR T cell generation to treat cancer and autoimmune disease @capstantx.bsky.social direct delivery of mRNA-encoded CARs to CD8+ T cells in mouse & NHP models shows tumor control not only in blood, but also tissue. Immune reset seen at B cell recovery www.science.org/doi/10.1126/...

In vivo CAR T cell generation to treat cancer and autoimmune disease

Chimeric antigen receptor (CAR) T cell therapies have transformed treatment of B cell malignancies. However, their broader application is limited by complex manufacturing processes and the necessity f...

www.science.org

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Sten Linnarsson @sten.linnarsson.org · Jun 19

Heads-up for major new faculty search at KI — with great startup packages and a wide range of subject areas.

Karolinska Institutet @ki.se · Jun 18

Save the date! On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility news.ki.se/ki-to-recruit-junior-researchers-with-a-focus-on-excellence

KI to recruit junior researchers with a focus on excellence

On 25 June, Karolinska Institutet will be starting a major recruitment drive for 20 junior researchers with a focus on excellence and mobility. As one of Europe’s leading medical universities, KI offe...

news.ki.se

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Sten Linnarsson @sten.linnarsson.org · May 28

Very cool work from James Zou. Link to paper: www.nature.com/articles/s41...

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Reposted by Sten Linnarsson

James Zou @jameszou.bsky.social · Mar 19

⚡️Really thrilled that #textgrad is published in @nature.com today!⚡️

We present a general method for genAI to self-improve via our new *calculus of text*.

We show how this optimizes agents🤖, molecules🧬, code🖥️, treatments💊, non-differentiable systems🤯 + more!

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Reposted by Sten Linnarsson

European Commission @ec.europa.eu · May 8

Choose Science. Choose Europe.

A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.

With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.

Apply by 10 September → europa.eu/!fBTMgF

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Shicheng Guo @shihcheng.bsky.social · May 27

Discover aptamers faster! UltraSelex combines partitioning, high-throughput sequencing & computation in 1 step. Revolutionize drug discovery! PMID:40164941, Nat Chem Biol 2025, @nchembio https://doi.org/10.1038/s41589-025-01868-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Single-step discovery of high-affinity RNA ligands by UltraSelex | Nature Chemical Biology

Aptamers, nucleic acid ligands targeting specific molecules, have emerged as drug candidates, sensors, imaging tools and nanotechnology building blocks. The predominant method for their discovery, systematic evolution of ligands by exponential enrichment, while successful, is laborious, time-consuming and often results in candidates enriched for unintended criteria. Here we present UltraSelex, a noniterative method that combines biochemical partitioning, high-throughput sequencing and computational signal-to-background rank modeling for discovering RNA aptamers in about 1 day. UltraSelex identified high-affinity RNA aptamers capable of binding a fluorogenic silicon rhodamine dye and two protein targets, the SARS-CoV-2 RNA-dependent RNA polymerase and HIV reverse transcriptase, enabling live-cell RNA imaging and efficient enzyme inhibition, respectively. From the ranked sequences, minimal aptamer motifs could be easily inferred. UltraSelex provides a rapid route to reveal new drug candi

doi.org

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Sten Linnarsson @sten.linnarsson.org · May 25

So we’ll be vibecoding science soon enough, and not just for DNA! The AI models need access to all of the literature, code and data of course. We’ll have to build fully autonomous labs for all common types of experiments. And then we hook it all up in a loop. Exciting times!

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