Jan Hartung
@janha.bsky.social
Physician & Neuroscientist. Systems neuroscience, cortical layer 1, neurology, neuroimmunology, biological patterns and dynamics.
Reposted by Jan Hartung
I'm pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, out in @cp-cellreports.bsky.social !
With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding.
(1/13)
With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding.
(1/13)
June 5, 2025 at 5:10 PM
I'm pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, out in @cp-cellreports.bsky.social !
With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding.
(1/13)
With Demi Brizee & David Dupret, we track how oscillations and spiking behaviour map onto hippocampal layers using an LFP-based embedding.
(1/13)
Reposted by Jan Hartung
📣New study in Neuron, featuring modeling insights: "Cell-Specific Dendritic Integration in Cortical GABAergic Interneurons"! It reveals PV & SST interneurons compute differently. This highlights how distinct dendrites enable specialized brain computations!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Distinct dendritic integration strategies control dynamics of inhibition in the neocortex
Dendrites critically influence single-neuron computations, but their role in neocortical GABAergic interneurons (INs) remains poorly understood. We fo…
www.sciencedirect.com
July 3, 2025 at 10:12 AM
📣New study in Neuron, featuring modeling insights: "Cell-Specific Dendritic Integration in Cortical GABAergic Interneurons"! It reveals PV & SST interneurons compute differently. This highlights how distinct dendrites enable specialized brain computations!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Jan Hartung
Question to the #neurobiology #evolution community: Can anyone point me to literature on the divergence in excitatory #neurotransmitter use between invertebrates and vertebrates? Specifically how insects got to mainly use acetylcholine and vertebrates glutamate? Thanks!
February 26, 2025 at 8:35 AM
Question to the #neurobiology #evolution community: Can anyone point me to literature on the divergence in excitatory #neurotransmitter use between invertebrates and vertebrates? Specifically how insects got to mainly use acetylcholine and vertebrates glutamate? Thanks!
Reposted by Jan Hartung
I'd like to build a map of maps in neuroscience. Who has done some aggregation work of putting together at all the existing data repositories, atlases, maps, etc. tackling electrophy, morpho, cell types, transcriptomes, connectomes (micro and meso) to figure out what we know about the brain?
January 23, 2025 at 4:21 PM
I'd like to build a map of maps in neuroscience. Who has done some aggregation work of putting together at all the existing data repositories, atlases, maps, etc. tackling electrophy, morpho, cell types, transcriptomes, connectomes (micro and meso) to figure out what we know about the brain?
Go work with Jonas!
I am honoured to join Saarland University as Professor of Physiology in February 2025. My department will focus on the network mechanisms of learning, with particular interest in synaptic function & computations of large neuronal populations. We are hiring, so feel free to get in touch!
January 16, 2025 at 9:11 PM
Go work with Jonas!
Reposted by Jan Hartung
I have a post-doc position to study the effect of AI on education.
How can we ensure that AI tools enhance natural intelligence?
The position is a part of the Estonian Centre of Excellence in Artificial Intelligence.
Please repost - not easy to get people to work in Estonia 🥶
#edusky #neuroAI
How can we ensure that AI tools enhance natural intelligence?
The position is a part of the Estonian Centre of Excellence in Artificial Intelligence.
Please repost - not easy to get people to work in Estonia 🥶
#edusky #neuroAI
January 13, 2025 at 12:19 PM
Reposted by Jan Hartung
tl;dr The problem with science isn’t how we talk about to Aunt Flo and Uncle Earl at Thanksgiving - it’s that we’ve knowingly made its central purpose career advancement at the expense of advancing the public good.
Basic scientists continue to completely miss the mark in identifying the real threat to basic science. The erosion of funding for basic research does not stem from a loss of public support - the public already love discovery research.
This is a way to frame basic science when we're talking to family, friends, voters. How ridiculous is it to study fly eyes or worm vulvae or yeast life? This lead to understanding cancer genes and enabled personalized medicine. Then, thank everyone listening to us for funding NIH and NSF
December 1, 2024 at 4:13 PM
tl;dr The problem with science isn’t how we talk about to Aunt Flo and Uncle Earl at Thanksgiving - it’s that we’ve knowingly made its central purpose career advancement at the expense of advancing the public good.
Looks pretty cool (and useful)!
Good news everyone! A new version of graph-tool is just out! @graph-tool.skewed.de
graph-tool.skewed.de
Graph-tool is a comprehensive and efficient Python library to work with networks, including structural, dynamical, and statistical algorithms, as well as visualization. 1/N
#networkscience
graph-tool.skewed.de
Graph-tool is a comprehensive and efficient Python library to work with networks, including structural, dynamical, and statistical algorithms, as well as visualization. 1/N
#networkscience
December 2, 2024 at 4:29 PM
Looks pretty cool (and useful)!
Reposted by Jan Hartung
For so many, there was a book - often read ~20yo - that had a very big influence on their next steps. Do you have a book story like that? Do tell!
My book was Crick's "Astonishing Hypothesis". I got to feature my 30yo tattered copy in a recent photo shoot.
www.thetransmitter.org/summer-readi...
My book was Crick's "Astonishing Hypothesis". I got to feature my 30yo tattered copy in a recent photo shoot.
www.thetransmitter.org/summer-readi...
November 18, 2024 at 12:00 PM
For so many, there was a book - often read ~20yo - that had a very big influence on their next steps. Do you have a book story like that? Do tell!
My book was Crick's "Astonishing Hypothesis". I got to feature my 30yo tattered copy in a recent photo shoot.
www.thetransmitter.org/summer-readi...
My book was Crick's "Astonishing Hypothesis". I got to feature my 30yo tattered copy in a recent photo shoot.
www.thetransmitter.org/summer-readi...
Can you tell apart real from fabricated histological images? (Solution below -->🧵)
In our new preprint we test how easy or difficult it is to spot "scientific images" synthesized with generative algorithms. #ImageForensics
www.biorxiv.org/content/10.1...
In our new preprint we test how easy or difficult it is to spot "scientific images" synthesized with generative algorithms. #ImageForensics
www.biorxiv.org/content/10.1...
January 26, 2024 at 4:33 PM
Can you tell apart real from fabricated histological images? (Solution below -->🧵)
In our new preprint we test how easy or difficult it is to spot "scientific images" synthesized with generative algorithms. #ImageForensics
www.biorxiv.org/content/10.1...
In our new preprint we test how easy or difficult it is to spot "scientific images" synthesized with generative algorithms. #ImageForensics
www.biorxiv.org/content/10.1...
Reposted by Jan Hartung
Inspired by the threads below, let's take a minute to remind ourselves of the research @hannahrsnyder.bsky.social might be excited about. How is it helping us understand mood?
Definitely not going to point to the forced swim test. But I am *very* excited about where the field is heading.
Definitely not going to point to the forced swim test. But I am *very* excited about where the field is heading.
OK, let's start some DISCOURSE: I respect a lot of animal research but I think that (1) rodent tasks like forced swim & open field have little parallel with human psychopathology and (2) supposedly anxious/depressed behaviors on them are adaptive. Convince me otherwise? #PsychSciSky ##neuroskyence
E.g., I really don't follow how folks with clinical experience in humans would think that the forced swim test has anything to do with human depression, let alone be *the* measure for it in mice for which drug or other intervention efficacy is determined.
November 18, 2023 at 2:54 PM
Inspired by the threads below, let's take a minute to remind ourselves of the research @hannahrsnyder.bsky.social might be excited about. How is it helping us understand mood?
Definitely not going to point to the forced swim test. But I am *very* excited about where the field is heading.
Definitely not going to point to the forced swim test. But I am *very* excited about where the field is heading.
Thread worthwhile reading 👇
1/2 Review aims at objective symptom localization to identify causal links between symptoms & neuroanatomy, which enables treatment via "modulating the corresponding neuroanatomy." Is it still plausible in 2023 that there is simple 1on1 mapping of brain states to mind states?
November 19, 2023 at 10:20 AM
Thread worthwhile reading 👇
Do you have recmmendations for kits/methods for mRNA FISH high-throughput experiments over many tissue slices?
Or alternative approaches to get single-cell resolution mRNA expression data for 6-10 genes (not necessarily in one experiment)?
Please retweet and thanks a lot!
Or alternative approaches to get single-cell resolution mRNA expression data for 6-10 genes (not necessarily in one experiment)?
Please retweet and thanks a lot!
November 15, 2023 at 6:14 PM
Do you have recmmendations for kits/methods for mRNA FISH high-throughput experiments over many tissue slices?
Or alternative approaches to get single-cell resolution mRNA expression data for 6-10 genes (not necessarily in one experiment)?
Please retweet and thanks a lot!
Or alternative approaches to get single-cell resolution mRNA expression data for 6-10 genes (not necessarily in one experiment)?
Please retweet and thanks a lot!
Reposted by Jan Hartung
🚨 Preprint alert!!Thrilled to share my work in Ruediger Klein lab @MPIforBI @IMPRS_ML w/Zhang Y, Christian P, Tobias S, Johanna M. How emotional valence is arranged in BLA? is it hard-wired/topography? here's what we found!
Genetically- and spatially-defined basolateral amygdala neurons control food consumption and social ...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
October 20, 2023 at 11:54 AM
🚨 Preprint alert!!Thrilled to share my work in Ruediger Klein lab @MPIforBI @IMPRS_ML w/Zhang Y, Christian P, Tobias S, Johanna M. How emotional valence is arranged in BLA? is it hard-wired/topography? here's what we found!
Reposted by Jan Hartung
Many researchers in cognitive neuroscience and deep learning seem to assume that inference in the brain is hierarchical.
Our new Nature Reviews Neuroscience paper questions this assumption and proposes the shallow brain hypothesis.
#neuroskyence #brain
www.nature.com/articles/s41...
Our new Nature Reviews Neuroscience paper questions this assumption and proposes the shallow brain hypothesis.
#neuroskyence #brain
www.nature.com/articles/s41...
October 27, 2023 at 2:17 PM
Many researchers in cognitive neuroscience and deep learning seem to assume that inference in the brain is hierarchical.
Our new Nature Reviews Neuroscience paper questions this assumption and proposes the shallow brain hypothesis.
#neuroskyence #brain
www.nature.com/articles/s41...
Our new Nature Reviews Neuroscience paper questions this assumption and proposes the shallow brain hypothesis.
#neuroskyence #brain
www.nature.com/articles/s41...
Reposted by Jan Hartung
𝗗𝗼𝘄𝗻 𝘄𝗶𝘁𝗵 𝗰𝗼𝗿𝘁𝗶𝗰𝗼-𝗰𝗲𝗻𝘁𝗿𝗶𝘀𝗺!
How deep is the brain? The shallow brain hypothesis
www.nature.com/articles/s41...
How deep is the brain? The shallow brain hypothesis
www.nature.com/articles/s41...
October 27, 2023 at 5:57 PM
𝗗𝗼𝘄𝗻 𝘄𝗶𝘁𝗵 𝗰𝗼𝗿𝘁𝗶𝗰𝗼-𝗰𝗲𝗻𝘁𝗿𝗶𝘀𝗺!
How deep is the brain? The shallow brain hypothesis
www.nature.com/articles/s41...
How deep is the brain? The shallow brain hypothesis
www.nature.com/articles/s41...
Nice thread on predictive coding in schizophrenia 👇
Oscillatory traveling waves reveal predictive coding abnormalities in schizophrenia
www.biorxiv.org/content/10.1...
#neuroscience
www.biorxiv.org/content/10.1...
#neuroscience
October 20, 2023 at 1:48 PM
Nice thread on predictive coding in schizophrenia 👇
Reposted by Jan Hartung
Neuroscience folks! What are your favorite examples of physiological data suggesting competitive dynamics? I mean examples of neural activity patterns that appear to be mutually exclusive or nearly so.
How much evidence is there for winner-take-all vs winner-take-some?
#Neuroskyence
How much evidence is there for winner-take-all vs winner-take-some?
#Neuroskyence
October 16, 2023 at 2:52 PM
Neuroscience folks! What are your favorite examples of physiological data suggesting competitive dynamics? I mean examples of neural activity patterns that appear to be mutually exclusive or nearly so.
How much evidence is there for winner-take-all vs winner-take-some?
#Neuroskyence
How much evidence is there for winner-take-all vs winner-take-some?
#Neuroskyence