Jasnah Kholin
jasnah.bsky.social
Jasnah Kholin
@jasnah.bsky.social
HKer, nidovirologist. Revstar & MayaKuro fangirl. 一个健康的社會不該只有一種聲音. 解散警隊. ★ she/佢 ★
Reposted by Jasnah Kholin
also, there are plenty of text to speech tools that just record and don't analyze and they've existed for nearly my entire life. we've got to stop allowing people to conflate direct, non-generative tools with genAI when they have a financial incentive to do so
November 10, 2025 at 4:16 PM
Reposted by Jasnah Kholin
Yes, and there were also significant changes and reforms made in ship operations, inspections, equipment, and navigational charts.
November 11, 2025 at 2:35 AM
Reposted by Jasnah Kholin
Specifically, it was the National Weather Service Modernization and Associated Restructuring, begun in the 70s, which completely overhauled how we predict and respond to rapid weather events.

vlab.noaa.gov/web/nws-heri...
The NWS Modernization and Associated Restructuring - A Retrospective (Part 1) - National Weather Service Heritage - Virtual Lab
Planned in the 1980s and implemented in the 1990s, the NWS Modernization and Associated Restructuring modernized the agency’s organization and technology to ensure more rapid detection of storms and d...
vlab.noaa.gov
November 11, 2025 at 1:50 AM
i mean, it's an accurate descriptor of Chickenshit Bob!
November 11, 2025 at 1:08 AM
Reposted by Jasnah Kholin
I am sometimes moved to the point of bursting by the beauty of the city at night, by the people who have labored to make it beautiful, by the reality that we do not have the option to ignore each other, by the knowledge that all we have is one another.
November 11, 2025 at 12:33 AM
Reposted by Jasnah Kholin
Is this a government or an extortion racket because I can’t tell the difference?
November 10, 2025 at 9:27 PM
Reposted by Jasnah Kholin
Zhengli's team has done the work here:
www.biorxiv.org/content/10.1...

It just shows that bat-to-bat ACE2 variety spans a larger diversity than bat-to-human ACE2 variety; with some generalist viruses being able to infect human & some bat species, but not all bat species.
www.biorxiv.org
November 10, 2025 at 9:07 PM
Reposted by Jasnah Kholin
Oh, I think I do.

Bat ACE2's are quite diverse between bat species

The authors used bat cells from spanish R. ferrumequinum bats (blue); whereas BANAL viruses originally came from R. malayanus bats (red)

SC2 will most likely replicate in the "right" R.mal bat cell lines; see below:
November 10, 2025 at 9:07 PM
Reposted by Jasnah Kholin
Nothing mysterious, as one would expect, turns out that there are other SARS-CoV-2 related viruses out there with similar potential.

With BANAL-236, scientists managed to isolate just one such example, but we're only scratching not just the surface, but a tiny point of a hair on the surface.
November 10, 2025 at 8:09 PM
Reposted by Jasnah Kholin
However, you pop in human ACE2 and TMPRSS2, and now BANAL-236 and SARS-CoV-2 can replicate well in the Rhinolophus cell line.

Why is that? Good question, and I don't know - however, it shows that this particular entry barrier between bats and humans is very low for SARS-CoV-2 related viruses.
November 10, 2025 at 8:09 PM