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Reposted by John Steele

Ellinor Alseth @ellinoralseth.bsky.social · 1d

Obsessed with this Journal of Immaterial Science article 🔥

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Reposted by John Steele

Oli Clarke @olibclarke.bsky.social · 13d

If you can't see sidechains, can you really call the resolution 3.3 Å..? 👀

And if you can't see sidechains, how do you know the helical symmetry is right..?

cryoEM papers @cryoempapers.bsky.social · 13d

Structural basis of Pseudomonas biofilm-forming functional amyloid FapC formation pubmed.ncbi.nlm.nih.gov/40991694/ #cryoem

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John Steele @jfcsteele.bsky.social · 13d

The proliferation of tools to generate predictive protein structures just underscores how important CASP is. There is no better way to allow unbiased & fair comparisons between tools!
predictioncenter.org/index.cgi
Such a shame NIH didn't renew funding

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Reposted by John Steele

Stephen Turner @stephenturner.us · 14d

Apple is entering the protein folding arena.
SimpleFold: Folding Proteins is Simpler than You Think arxiv.org/abs/2509.18480 🧬🖥️🧪 github.com/apple/ml-sim...

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Reposted by John Steele

The Wallace Lab @swallacelab.bsky.social · 16d

Ever wondered where your paracetamol comes from? Spoiler: crude oil. In this study – led by Nick Johnson from our lab in collaboration with @astra-zeneca.bsky.social – we show how biology and chemistry can work together to create a more sustainable alternative. (1/n)

www.nature.com/articles/s41...

A biocompatible Lossen rearrangement in Escherichia coli - Nature Chemistry

Biocompatible chemistry merges chemo-catalytic reactions with cellular metabolism for sustainable small-molecule synthesis. Now a biocompatible Lossen rearrangement has been demonstrated to control ba...

www.nature.com

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Reposted by John Steele

Annis Richardson @drannisr.bsky.social · 17d

The Plant Shape Lab is hiring! Are you interested in supporting cutting edge cereal research? We are looking for an enthusiastic and dedicated technician to join us for 2 years, setting up and running cereal transformation. Find out more, and apply here: elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

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Reposted by John Steele

Mo Ali | مح علي @moali.bsky.social · 20d

If you're on LinkedIn, you'll probably want to switch this toggle to 'off'.

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Reposted by John Steele

Black In Plant Science- UK @blackinplantsci.bsky.social · 28d

📢Deadlines fast approaching for the BiPS Conference 2025!

Join us for a day of connection and celebration where we'll be hearing from the renowned academics Nicola Patron and Kevin Cox. With workshops on a variety of topics and a chance for you to build your community.

Register: buff.ly/J9PM0Wj

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Reposted by John Steele

Marcin J. Suskiewicz @msuskiewicz.bsky.social · Sep 5

I supervise an excellent postdoc who's looking for a postdoc or associate position in < 1 yr. Highly skilled in chem biol and biochem (peptide synthesis, native chem ligation, bacterial expression, purification, intein-based splicing, crystallography, interaction assays). Contact me if interested.

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John Steele @jfcsteele.bsky.social · Aug 26

SULSA is running an Industry Academia conference on 28th & 29th October.
Looks fantastic for researchers working in Scotland- particularly good for students interested in learning more about industry & working on skill development!
sulsa.ac.uk/indac/

IndAc Conference - SULSA

sulsa.ac.uk

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Reposted by John Steele

Oli Clarke @olibclarke.bsky.social · Jul 29

Food for thought here for anyone not working at TRUE atomic resolution…

Structural Biology @actacrystd.iucr.org · Jul 29

Andreas Ehler et al.: A high-resolution data set of fatty acid-binding protein structures. III. Unexpectedly high occurrence of wrong ligands #StructureBasedDrugDesign #FattyAcidBindingProteins #LigandBinding doi.org/10.1107/S205... #IUCr

A high-resolution data set of fatty acid-binding protein structures. III. Unexpectedly high occurrence of wrong ligands

Very high-resolution fatty acid-binding protein structures identified a substantial number of ligands that differ strongly from their expected structure. If different ligand chemistry is a potentially...

doi.org

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John Steele @jfcsteele.bsky.social · Jul 8

I had no idea about this! Amazon owns AbeBooks!

Pookleblinky @pookleblinky.bsky.social · Jul 8

Note for book buyers: AbeBooks *is* amazon. Amazon has owned AbeBooks since 2008.

It's been Amazon for 17 years, think about how hard amazon has worked to hide this if you didn't know this.

Abra, The Everwife 🏳️‍⚧️ 🇲🇽🌼👻 @pairofclaws.bsky.social · Jul 8

This Prime Day, celebrate by buying trans books from somewhere other than Amazon.

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Reposted by John Steele

Randy Read 🇨🇦🇬🇧 @randyjread.bsky.social · Jul 3

If this is true, it’s abysmally shortsighted for #NIH. The new tools nurtured by the long series of #CASP challenges probably contribute far more in one year to the scientific and industrial economies than the entire funds that have supported it.

Science Magazine @science.org · Jul 2

Exclusive: An international scientific competition widely credited with spurring the development of artificial intelligence for biology appears to be on its deathbed. scim.ag/44ukS90

Exclusive: Famed protein structure competition nears end as NIH grant money runs out

Agency silent on funding renewal for contest that inspired creation of AIs that predicted how proteins would fold

scim.ag

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John Steele @jfcsteele.bsky.social · Jul 1

Great thread- thanks for sharing!

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Reposted by John Steele

Matthew Cobb @matthewcobb.bsky.social · Jun 26

Just learned that Frank Stahl (of the Meselson and Stahl DNA replication experiment ("the most beautiful experiment in biology") died at the beginning of April, to no fanfare. Here's a lovely video of them reminiscing: www.youtube.com/watch?v=7-tn...

The Most Beautiful Experiment: Meselson and Stahl

YouTube video by Science Communication Lab

www.youtube.com

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Reposted by John Steele

Roli Roberts @roliroberts.bsky.social · Jun 27

Interested in trying out life as a scientific #editor? Based in the UK? Background in #PlantScience? The @plosbiology.org crew is expanding (again!), so a place in our lovely team might be for you...

Nonia Pariente @npariente.bsky.social · Jun 26

I am recruiting - if you have a background in plant mol cell bio, a keen interest in sustainability and planetary health and are looking to move away from the bench, this may be for you!

Have a 👀 and please reach out if Qs

1yr FTC, remote in the UK

job-boards.eu.greenhouse.io/plos/jobs/46...

PLOS Biology Associate Editor- FTC

UK-Remote

job-boards.eu.greenhouse.io

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Reposted by John Steele

Physiologia Plantarum @pplplantarum.bsky.social · Jun 25

🧬 New toolkit for engineering Chlamydomonas plastomes!
MoCloro brings Golden Gate modular cloning to algal chloroplasts — enabling fast, multigene integration & homoplasmy in 2 months 🌿

🔗 https://bit.ly/4jMNhfU ##SyntheticBiology #Chlamydomonas #Microalgae #Plantscience

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Reposted by John Steele

Eric Topol @erictopol.bsky.social · Jun 23

This is wild!
Engineering E. coli bacteria to turn plastic waste into paracetamol (Tylenol)
www.nature.com/articles/s41...
www.nature.com/articles/s41...

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John Steele @jfcsteele.bsky.social · Jun 23

Always exciting when research from the lab is disseminated for the public! @theguardian.com have reported on @swallacelab.bsky.social paper turning plastic into paracetamol using engineered bacteria
tinyurl.com/32hxnwsd (original publication rdcu.be/esYfF)

Scientists use bacteria to turn plastic waste into paracetamol

Genetically modified E coli used to create painkillers from material produced from plastic bottles

www.theguardian.com

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John Steele @jfcsteele.bsky.social · May 23

thanks for sharing an accessible version!
I don't know any postdoc who hasn't echoed these feelings. I really hope funders & institutions read & listen to examples like this, but I'm not holding my breath!

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Reposted by John Steele

Jacob Aron @jjaron.bsky.social · May 19

Would you like to write for New Scientist? We always work with freelancers, but occasionally I put out a call like this for new writers. I'm looking for 300-700 word news stories about new discoveries. Don't pitch us press releases or the big journals, we have those covered. Pay starts at 51p/word

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Reposted by John Steele

Edouard Machery @edouardmachery.bsky.social · Apr 18

the ERC has added a million euro for researchers moving to Europe.

ERC to double allowance for researchers moving to EU

The European Research Council (ERC) is doubling the relocation allowance it makes to researchers coming to the EU to take up one of its grants. At present it offers third-country researchers up to €1 ...

sciencebusiness.net

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Reposted by John Steele

Cecilia Blikstad @cblikstad.bsky.social · Apr 16

Come join us as a postdoc! We have an open position in biochemistry of cyanobacterial CO2 fixation focusing on regulation of carboxysome function! Please help me spread the word and welcome to apply! www.blikstadlab.org/open-positio...

Open positions

Postdoctoral scholar in biochemistry of cyanobacterial CO 2 fixation The Blikstad research group is searching for a postdoc to study fundamental principles of CO 2 fixation in cyanobacteria. Our...

www.blikstadlab.org

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John Steele @jfcsteele.bsky.social · Apr 14

Fantastic piece in @natplants.nature.com uncovering an ancient mechanism controlling cell fate across land plants from Maize to moss- protein stability is key!

Great work led by @mjprigge.bsky.social & coming out of the labs of @luciastrader.bsky.social & @drannisr.bsky.social
rdcu.be/ehFgk

Comparative mutant analyses reveal a novel mechanism of ARF regulation in land plants

Nature Plants - Comparative analysis of maize and moss reveals a 500-million-year-old piece of the auxin-signalling puzzle that controls the protein level of ARFs, key transcriptional regulators.

rdcu.be

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John Steele @jfcsteele.bsky.social · Apr 11

a baby is covering his face with his hand .

ALT: a baby is covering his face with his hand .

media.tenor.com

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