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Jorge Ferreira

@jorgeferreira.bsky.social

2K followers 2K following 140 posts

Cell biologist at i3S - University of Porto Associate Professor - Faculty of Medicine of Porto At the crossroads between nuclear mechanics and cell division. https://integrativenucleus.weebly.com/

integrativenucleus.weebly.com

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Jorge Ferreira @jorgeferreira.bsky.social · Sep 3

New preprint from the lab! Please check it out. 🚨
Have you ever wondered how cells decide when it’s time to divide? So did we!
www.biorxiv.org/content/10.1...

Chromosome condensation mechanically primes the nucleus for mitosis

Timely and accurate transition into mitosis is essential to preserve genome integrity and avoid chromosome segregation errors. This transition depends on spatial and temporal activity patterns of the ...

www.biorxiv.org

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Jorge Ferreira @jorgeferreira.bsky.social · 1d

www.cam.ac.uk/research/new...

Nobel Laureate Professor Sir John Gurdon dies aged 92

It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.

www.cam.ac.uk

Jorge Ferreira @jorgeferreira.bsky.social · 2d

Done! Thanks for the interest

Jorge Ferreira @jorgeferreira.bsky.social · 7d

Was a real pleasure! And congrats to Nelson on his amazing defense

Reposted by Jorge Ferreira

Guillaume Charras @gcharras.bsky.social · 10d

Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients.

More here: elifesciences.org/reviewed-pre...

elifesciences.org

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Reposted by Jorge Ferreira

Barriga Lab @eliasbarrigalab.bsky.social · 15d

Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!

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Jorge Ferreira @jorgeferreira.bsky.social · 24d

Congrat Sachin! Excellent work

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Reposted by Jorge Ferreira

Elaine Emmerson @doctoremmerson.bsky.social · 26d

I am advertising for a #postdoc for a 3 year BBSRC-funded project exploring the role of macrophages in salivary gland development. The successful candidate will be based at @edinuni-irr.bsky.social at @uni-of-edinburgh.bsky.social. Closing date: 9th Oct. elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

Postdoctoral Research Fellow

An exciting opportunity has arisen to join the Emmerson lab within the Institute for Regeneration and Repair at the University of Edinburgh. This three year, BBSRC-funded postdoctoral research associa...

elxw.fa.em3.oraclecloud.com

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Jorge Ferreira @jorgeferreira.bsky.social · Sep 4

Congrats! Beautiful work, as usual.

Jorge Ferreira @jorgeferreira.bsky.social · Sep 3

No worries. Let's try to catch up one of these days

Jorge Ferreira @jorgeferreira.bsky.social · Sep 3

Thanks! I really enjoyed reading your last paper as well!

Jorge Ferreira @jorgeferreira.bsky.social · Sep 3

Thanks! Let´s see how it goes

Jorge Ferreira @jorgeferreira.bsky.social · Sep 3

Please do reach out if you have any questions/suggestions.

Jorge Ferreira @jorgeferreira.bsky.social · Sep 3

This mechanosensitive mechanism ensures that mitosis only occurs once chromosomes are sufficiently condensed, avoiding potential segregation errors caused by premature mitotic entry.

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Jorge Ferreira @jorgeferreira.bsky.social · Sep 3

We further demonstrate how mitotic chromosome condensation generates a mechanical signal on the nuclear envelope during prophase. This mechanical signal coordinates the multiple steps required for mitotic entry such as cyclin B1 nuclear translocation and dynein binding to nuclear pores.

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Jorge Ferreira @jorgeferreira.bsky.social · Sep 3

In this new work, we show that irreversible mitotic commitment is driven by chromosome condensation that takes place inside the prophase nucleus.

Jorge Ferreira @jorgeferreira.bsky.social · Sep 3

New preprint from the lab! Please check it out. 🚨
Have you ever wondered how cells decide when it’s time to divide? So did we!
www.biorxiv.org/content/10.1...

Chromosome condensation mechanically primes the nucleus for mitosis

www.biorxiv.org

4 14 36

Reposted by Jorge Ferreira

Tobias Warnecke @tobiaswarnecke.bsky.social · Sep 1

Please re-post: If you know (or are!) somebody who might fancy doing a PhD (Oct 2026 start) in my group @oxfordbiochemistry.bsky.social, working on chromatin evolution in prokaryotes (or other things we're interested in), please have a look at www.bioch.ox.ac.uk/supervisors-...

Supervisors and Projects

www.bioch.ox.ac.uk

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Reposted by Jorge Ferreira

luskinglab.bsky.social @luskinglab.bsky.social · Jul 21

Join us for the first Mechanobiology of the Nucleus conference supported by @faseborg.bsky.social. Co-organized with @lammerdinglab.bsky.social, @katemiro.bsky.social and Verena Ruprecht, the amazing program is here:
events.faseb.org/event/Mechan...
Opportunities for talks! Abstracts by Aug. 31st.

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Reposted by Jorge Ferreira

Seema Grewal @seemagrewal.bsky.social · Jul 16

Excited for our next special issue and looking forward to working with Abby Buchwalter (@abbybuch.bsky.social) and Megan King (@luskinglab.bsky.social)! Working on the cell biology of the nucleus? Send your papers our way!
#notforprofit

Journal of Cell Science @jcellsci.bsky.social · Jul 16

Call for papers: Cell Biology of the Nucleus

We invite you to submit your latest research to our special issue: Cell Biology of the Nucleus, guest edited by Abby Buchwalter @abbybuch.bsky.social, working alongside Megan King @luskinglab.bsky.social.
journals.biologists.com/jcs/pages/nu...

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Jorge Ferreira @jorgeferreira.bsky.social · Jul 17

Looking forward! Promises to be an amazing conference!

Jan Lammerding - Lab @lammerdinglab.bsky.social · Jul 16

Interested in nuclear #mechanobiology? Join us for the first ever FASEB Science Research Conference on the Mechanobiology of the Nucleus #MBNSRC.
Find more information and register at: events.faseb.org/event/Mechan...
Submit abstracts by August 31, 2025. Please share and see you in October!

Jorge Ferreira @jorgeferreira.bsky.social · Jul 10

Just learned of the passing of Frank Stahl. Together with Mat Meselson, he figured out one of the most amazing processes in biology. How does DNA replicate? Check out the beautiful movie made by iBiology and celebrate their legacy! www.ibiology.org/genetics-and...

The Most Beautiful Experiment: Meselson and Stahl • iBiology

Matt Meselson and Frank Stahl share the story of their groundbreaking experiment from 1958 that definitively showed semiconservative DNA replication.

www.ibiology.org

Reposted by Jorge Ferreira

Manuel Thery @manuelthery.bsky.social · Jul 8

Ever wished to become an actin star? 😎
Then try getting suspended above a non-adhesive substrate.
www.nature.com/articles/s41...

A multicellular star-shaped actin network underpins epithelial organization and connectivity - Nature Communications

The combined role of cellular junctions and actomyosin networks in tissues remains unclear. Here, the authors identify a tissue-scale star-shaped network of actomyosin that preserves cell shape, limit...

www.nature.com

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Jorge Ferreira @jorgeferreira.bsky.social · Jul 8

I suppose there are worst places to grade exams.

Reposted by Jorge Ferreira

EMBO @embo.org · Jul 1

Welcome and congratulations to the 60 new members and 9 associate members who have been elected to the EMBO Membership! This honour celebrates #research excellence and outstanding achievements in the #LifeSciences. 🧪

Learn more here:
www.embo.org/press-releas... #EMBOMembers2025

Outstanding life scientists elected to the EMBO Membership – Press releases – EMBO

Sixty-nine new members join the community of leading life scientists in Europe and beyond

www.embo.org

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Reposted by Jorge Ferreira

European Research Council (ERC) @erc.europa.eu · Jun 17

📣 Good news: 281 top researchers have just won ERC Advanced Grants!

The new funding, worth nearly €721 million, is part of the 🇪🇺 EU’s #HorizonEurope programme.

Find out more 👉 europa.eu/!JYKxkD

#ERCAdG #FrontierResearch @ec.europa.eu

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