Josien
@joscience.bsky.social
#astrocytes fanatic. Studying the stars of the brain in sensory processing. Also SciCom, books, music and running.
Reposted by Josien
@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below.
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
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Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
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November 10, 2025 at 4:43 PM
@sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below.
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social.
(1/2)
Reposted by Josien
Many of our big insights into brain function come from trying to mimic it, writes @timothyoleary.bsky.social. This lesson should guide how we organize research programs.
www.thetransmitter.org/systems-neur...
#neuroskyence
www.thetransmitter.org/systems-neur...
#neuroskyence
Neuroscience needs engineers—for more reasons than you think
Adopting an engineering mindset will help the field focus its research priorities.
www.thetransmitter.org
November 3, 2025 at 2:22 PM
Many of our big insights into brain function come from trying to mimic it, writes @timothyoleary.bsky.social. This lesson should guide how we organize research programs.
www.thetransmitter.org/systems-neur...
#neuroskyence
www.thetransmitter.org/systems-neur...
#neuroskyence
Reposted by Josien
This was a fabulous, once in a lifetime colloquium -- and now the videos are available in high quality on the College de France web site @college-de-france.fr
www.college-de-france.fr/fr/agenda/co...
With talks by Edvard Moser, Nancy Kanwisher, Liz Spelke, Manuela Piazza, Luca Bonatti and more!
www.college-de-france.fr/fr/agenda/co...
With talks by Edvard Moser, Nancy Kanwisher, Liz Spelke, Manuela Piazza, Luca Bonatti and more!
November 2, 2025 at 3:08 PM
This was a fabulous, once in a lifetime colloquium -- and now the videos are available in high quality on the College de France web site @college-de-france.fr
www.college-de-france.fr/fr/agenda/co...
With talks by Edvard Moser, Nancy Kanwisher, Liz Spelke, Manuela Piazza, Luca Bonatti and more!
www.college-de-france.fr/fr/agenda/co...
With talks by Edvard Moser, Nancy Kanwisher, Liz Spelke, Manuela Piazza, Luca Bonatti and more!
Reposted by Josien
We are doing it again!!!!
Save the date for the next in-person #AstrocyteCafe next June 3-5 (2026) in Pamplona (Spain)!
We can’t wait to see many of you in person again, thanks so much to the main local organizer @maitesolas.bsky.social ♥️
Save the date for the next in-person #AstrocyteCafe next June 3-5 (2026) in Pamplona (Spain)!
We can’t wait to see many of you in person again, thanks so much to the main local organizer @maitesolas.bsky.social ♥️
November 2, 2025 at 11:26 AM
We are doing it again!!!!
Save the date for the next in-person #AstrocyteCafe next June 3-5 (2026) in Pamplona (Spain)!
We can’t wait to see many of you in person again, thanks so much to the main local organizer @maitesolas.bsky.social ♥️
Save the date for the next in-person #AstrocyteCafe next June 3-5 (2026) in Pamplona (Spain)!
We can’t wait to see many of you in person again, thanks so much to the main local organizer @maitesolas.bsky.social ♥️
Reposted by Josien
This is so good from Cory Doctorow on all the tricks Amazon uses to get both consumers to pay more, and how businesses on the platform end up paying it 45-51 cents on every dollar.
Plus he rightly calls for regulatory change, not just individual consumer action
www.theguardian.com/technology/2...
Plus he rightly calls for regulatory change, not just individual consumer action
www.theguardian.com/technology/2...
Way past its prime: how did Amazon get so rubbish?
Sick of scrolling through junk results, AI-generated ads and links to lookalike products? The author and activist behind the term ‘enshittification’ explains what’s gone wrong with the internet – and ...
www.theguardian.com
October 5, 2025 at 8:19 AM
This is so good from Cory Doctorow on all the tricks Amazon uses to get both consumers to pay more, and how businesses on the platform end up paying it 45-51 cents on every dollar.
Plus he rightly calls for regulatory change, not just individual consumer action
www.theguardian.com/technology/2...
Plus he rightly calls for regulatory change, not just individual consumer action
www.theguardian.com/technology/2...
Reposted by Josien
💡 Research Spotlight: Primary cilia in astrocytes are key for their development, metabolism & synaptic regulation. Defects lead to neuronal and behavioral issues in mice, offering new insights into neurodevelopment & ciliopathies.
🔗 https://www.nature.com/articles/s41593-024-01726-z
🔗 https://www.nature.com/articles/s41593-024-01726-z
Primary cilia signaling in astrocytes mediates development and regional-specific functional specification - Nature Neuroscience
Astrocyte diversity is greatly influenced by local environmental modulation. Wang et al. report a critical role for astrocytic primary cilia in transmitting local cues that drive the region-specific diversification of astrocytes within the developing mouse brain.
www.nature.com
October 23, 2025 at 10:49 AM
💡 Research Spotlight: Primary cilia in astrocytes are key for their development, metabolism & synaptic regulation. Defects lead to neuronal and behavioral issues in mice, offering new insights into neurodevelopment & ciliopathies.
🔗 https://www.nature.com/articles/s41593-024-01726-z
🔗 https://www.nature.com/articles/s41593-024-01726-z
The posters are on the wall. Ready for the festival della scienza 2025 starting tomorrow! Excited to see the kids amazed by the multisensory illusions! 🧠🤯🤩
October 22, 2025 at 9:29 PM
The posters are on the wall. Ready for the festival della scienza 2025 starting tomorrow! Excited to see the kids amazed by the multisensory illusions! 🧠🤯🤩
Reposted by Josien
Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice
Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering.
www.nature.com/articles/s41...
Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering.
www.nature.com/articles/s41...
Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice - Nature Communications
The authors present the adaptive optics system MD-FSS, which allows high-resolution brain imaging in awake mice with rapid aberrations correction against motion. It reveals differences in brain functi...
www.nature.com
October 19, 2025 at 5:49 PM
Rapid adaptive optics enabling near noninvasive high-resolution brain imaging in awake behaving mice
Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering.
www.nature.com/articles/s41...
Under 2P excitation, adaptive optics measures the aberrated point spread function in ≈0.1 s/measurement, compensating for aberrations and scattering.
www.nature.com/articles/s41...
Reposted by Josien
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
October 15, 2025 at 6:33 AM
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
Reposted by Josien
Loved working with our amazing outreach team on this short video about representational drift! @crmatematica.bsky.social
🧠🧪
In it, I explain the points we make in our recent review in CONEUR:
doi.org/10.1016/j.co...
🧠🧪
In it, I explain the points we make in our recent review in CONEUR:
doi.org/10.1016/j.co...
Memories feel fixed, but the brain never stands still.
@j-b-eppler.bsky.social talks about representational drift; how memories remain stable even as the neurons behind them constantly change.
youtu.be/z63fmYSBcB0
#Neuroscience #Mathematics #Memory #Brain #CognitiveScience #Neurobiology #Research
@j-b-eppler.bsky.social talks about representational drift; how memories remain stable even as the neurons behind them constantly change.
youtu.be/z63fmYSBcB0
#Neuroscience #Mathematics #Memory #Brain #CognitiveScience #Neurobiology #Research
Why Your Brain Is Never Still: Representational Drift and Statistical Learning
YouTube video by Centre de Recerca Matemàtica
youtu.be
October 14, 2025 at 2:22 PM
Loved working with our amazing outreach team on this short video about representational drift! @crmatematica.bsky.social
🧠🧪
In it, I explain the points we make in our recent review in CONEUR:
doi.org/10.1016/j.co...
🧠🧪
In it, I explain the points we make in our recent review in CONEUR:
doi.org/10.1016/j.co...
Reposted by Josien
Problemen rond wetenschappelijke integriteit halen zelden de media. Dinsdag vertel ik waarom dat problematisch is voor het publieke vertrouwen in de wetenschap en de media, bij een colloquium van @isis-radboud.bsky.social, @willemhalffman.bsky.social. Ook @elisabethbik.bsky.social is van de partij!
October 9, 2025 at 9:17 AM
Problemen rond wetenschappelijke integriteit halen zelden de media. Dinsdag vertel ik waarom dat problematisch is voor het publieke vertrouwen in de wetenschap en de media, bij een colloquium van @isis-radboud.bsky.social, @willemhalffman.bsky.social. Ook @elisabethbik.bsky.social is van de partij!
Reposted by Josien
Als de woorden worst en burger al zo verwarrend zijn voor de mensen, waarom maakt de Europese Unie zich dan niet druk over partijen die vrijheid of democratie ten onrechte in hun naam hebben staan?
October 8, 2025 at 1:46 PM
Als de woorden worst en burger al zo verwarrend zijn voor de mensen, waarom maakt de Europese Unie zich dan niet druk over partijen die vrijheid of democratie ten onrechte in hun naam hebben staan?
Reposted by Josien
“It actually doesn’t take much to be considered a difficult woman. That’s why there are so many of us.”
www.reuters.com/business/env...
www.reuters.com/business/env...
Wildlife advocate, primate expert Jane Goodall dies at 91
Scientist and global activist Jane Goodall, who turned her childhood love of primates into a lifelong quest for protecting the environment, died on Wednesday at the age of 91, the institute she founded said.
www.reuters.com
October 2, 2025 at 5:39 AM
“It actually doesn’t take much to be considered a difficult woman. That’s why there are so many of us.”
www.reuters.com/business/env...
www.reuters.com/business/env...
Reposted by Josien
A pair of papers on using holographic optogenetics and compressed sensing for connectomics:
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing
www.nature.com/articles/s41...
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing
www.nature.com/articles/s41...
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing - Nature Neuroscience
The authors develop a new computational system for high-throughput mapping of synaptic connectivity using two-photon holographic optogenetics and intracellular recordings.
www.nature.com
September 19, 2025 at 4:15 AM
A pair of papers on using holographic optogenetics and compressed sensing for connectomics:
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing
www.nature.com/articles/s41...
Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing
www.nature.com/articles/s41...
Reposted by Josien
We’ve known for some time that air #pollution is bad for human #health. But the focus was mostly on the lungs and heart. Yet somewhere along the way, it became more mainstream to consider how air pollution might affects brains too. What I found surprising was the recency of that.
#neuroskyence
#neuroskyence
How does air pollution impact your brain? - Neurofrontiers
Air pollution is increasingly recognized as having negative effects on brain health. Here we take a look at what those are.
neurofrontiers.blog
September 14, 2025 at 6:25 PM
We’ve known for some time that air #pollution is bad for human #health. But the focus was mostly on the lungs and heart. Yet somewhere along the way, it became more mainstream to consider how air pollution might affects brains too. What I found surprising was the recency of that.
#neuroskyence
#neuroskyence
Reposted by Josien
Thrilled to share that our work is now published in Science! ✨
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
September 11, 2025 at 8:14 PM
Thrilled to share that our work is now published in Science! ✨
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭
www.science.org/doi/10.1126/...
🧵1/
Reposted by Josien
This is infuriating. What is the point of a Marine Protected Area if trawlers are allowed to keep ploughing it?
Yet again, the government has succumbed to commercial lobbying.
www.theguardian.com/environment/...
Yet again, the government has succumbed to commercial lobbying.
www.theguardian.com/environment/...
Bottom trawling to continue in English protected waters, government rules
Defra says blanket ban on ‘destructive’ fishing practice disproportionate as MPs urge minister to reconsider
www.theguardian.com
September 9, 2025 at 6:15 AM
This is infuriating. What is the point of a Marine Protected Area if trawlers are allowed to keep ploughing it?
Yet again, the government has succumbed to commercial lobbying.
www.theguardian.com/environment/...
Yet again, the government has succumbed to commercial lobbying.
www.theguardian.com/environment/...
Reposted by Josien
There is no reasonable justification not to ban bottom trawling everywhere.
The fishing method can destroy the habitat on the seabed, and the nets “literally sweep up everything in their path”.
Ban bottom trawling in 'protected' zones
Public urged to back ban on destructive fishing in protected areas.
theecologist.org
August 28, 2025 at 1:12 PM
There is no reasonable justification not to ban bottom trawling everywhere.
Reposted by Josien
Thanks so much @dorsaamir.bsky.social and @chazfirestone.bsky.social, along with @mcxfrank.bsky.social, for your input on this! And ofc @sarahexplains.bsky.social and @parshallison.bsky.social for your editing!
How much does the environment we’re raised in change how we see the world? Wonderful piece in @sciam.bsky.social by @norabradford.bsky.social, ft. an interview with @dorsaamir.bsky.social about our work on the 'cultural byproduct hypothesis'.
www.scientificamerican.com/article/does...
www.scientificamerican.com/article/does...
Why a Classic Psychology Theory about Vision Has Fallen Apart
The downfall of a long-standing theory in psychology raises a question: How much does the environment we’re raised in change how we literally see the world?
www.scientificamerican.com
August 22, 2025 at 5:29 PM
Thanks so much @dorsaamir.bsky.social and @chazfirestone.bsky.social, along with @mcxfrank.bsky.social, for your input on this! And ofc @sarahexplains.bsky.social and @parshallison.bsky.social for your editing!
Reposted by Josien
Here’s the blunt reality — reasonably-sized electric vehicles need to be the future of cars, but cars can’t be the future of urban mobility.
Fewer cars.
Less driving.
More inviting mobility choices.
Better communities and cities.
These are the 4 pillars of the REAL urban transportation solution.
Fewer cars.
Less driving.
More inviting mobility choices.
Better communities and cities.
These are the 4 pillars of the REAL urban transportation solution.
November 12, 2024 at 3:31 PM
Here’s the blunt reality — reasonably-sized electric vehicles need to be the future of cars, but cars can’t be the future of urban mobility.
Fewer cars.
Less driving.
More inviting mobility choices.
Better communities and cities.
These are the 4 pillars of the REAL urban transportation solution.
Fewer cars.
Less driving.
More inviting mobility choices.
Better communities and cities.
These are the 4 pillars of the REAL urban transportation solution.
Reposted by Josien
Reposted by Josien
Thanks to @thetransmitter.bsky.social and @ldattaro.bsky.social for this coverage of our recent paper!
Some neurons respond more strongly to visual stimuli than others. But the rest of the brain doesn’t prioritize signals from those neurons, according to a new study. Read more in this month’s Null and Noteworthy.
By @ldattaro.bsky.social
#neuroskyence
www.thetransmitter.org/null-and-not...
By @ldattaro.bsky.social
#neuroskyence
www.thetransmitter.org/null-and-not...
Null and Noteworthy: Downstream brain areas read visual cortex signals en masse in mice
The finding contradicts a theory that the regions prioritize neurons that are adept at identifying specific stimuli. Plus, a response to a study that questioned immune memory in astrocytes.
www.thetransmitter.org
August 1, 2025 at 1:56 AM
Thanks to @thetransmitter.bsky.social and @ldattaro.bsky.social for this coverage of our recent paper!
Reposted by Josien
Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals - Nature Neuroscience
The relative contribution of intrinsic and extrinsic factors to astrocyte heterogeneity is unknown. Using heterotropic transplantation of septal astrocytes with distinct lineage origins, we show that ...
www.nature.com
July 31, 2025 at 5:06 PM
Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals
www.nature.com/articles/s41...
www.nature.com/articles/s41...