Jayna Raghwani
@jraghwani.bsky.social
150 followers 250 following 8 posts
Computational biologist | Virus evolution & ecology | Genomics
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Jayna Raghwani @jraghwani.bsky.social · 9d
cc: @microbiologysociety.org
Jayna Raghwani @jraghwani.bsky.social · 9d
Excited to share that our paper on the relationship between viral load and metagenomic outputs in wildlife samples is now published in Microbial Genomics @microbiologysociety! 🎉 Fantastic collaboration with a brilliant team.

More info: 📖 tinyurl.com/ywb7tvjm
Quantifying viral load and characterizing virus diversity in wildlife samples with target enrichment sequencing
Metagenomics is a powerful tool for characterizing viruses, with broad applications across diverse disciplines, from understanding the ecology and evolutionary history of viruses to identifying causat...
tinyurl.com
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Reposted by Jayna Raghwani
zaminiqbal.bsky.social
Zamin Iqbal @zaminiqbal.bsky.social · 28d
Sometimes you meet absolutely incredible bioinfo-magicians.
It was a huge privilege when @shenwei356.bsky.social
joined our group for a year on an @embl.org sabbatical.
While here, he developed a new way of aligning to
millions of bacteria, called LexicMap 1/n
www.nature.com/articles/s41...
Efficient sequence alignment against millions of prokaryotic genomes with LexicMap - Nature Biotechnology
LexicMap uses a fixed set of probes to efficiently query gene sequences for fast and low-memory alignment.
www.nature.com
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Reposted by Jayna Raghwani
plosbiology.org
PLOS Biology @plosbiology.org · Aug 22
Will a #virus spillover into a new host species lead to dead-end infection or sustained #epidemic? This study uses a nematode-virus model to show that early #spillover traits, especially infection prevalence & shedding, are important predictors of viral persistence @plosbiology.org 🧪 plos.io/3UCnZHp
Top: Experimental design depicting the passage experiment and the methods for quantifying infection prevalence, shedding ability, and infection prevalence in spillover populations. Middle: Host strains are ordered by the number of virus-positive plates over the course of the experiment (positive control C. elegans strain JU1580 set farthest right). Passage 0 denotes the exposure population. Note that the extraction procedure for passage 0 plates was different from the subsequent passages; many adult worms were removed from passage 0 populations to measure infection prevalence, intensity, and shedding (see methods). Bottom: Strains differed in epidemiological characteristics including B) maximum likelihood prevalence of infection, C) infection intensity (corrected median Ct), D) maximum likelihood shedding ability (the probability that 1 infected worm could cause visible fluorescence on a shedding plate), and E) relative susceptibility.
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Reposted by Jayna Raghwani
alibat.bsky.social
Dr Alison Peel @alibat.bsky.social · Jul 21
🦇 NEW RESEARCH: Our 3-year study of Australian flying foxes identified six co-circulating coronaviruses, with highest rates of infection and co-infection in young bats, and evidence of circulating recombinants 🧪🌏 🧵

Available open access in @natcomms.nature.com

📄 www.nature.com/articles/s41...
Synchronized seasonal excretion of multiple coronaviruses coincides with high rates of coinfection in immature bats - Nature Communications
Bats harbor diverse coronaviruses but temporal dynamics are less well studied. Here, the authors analyzed coronaviruses in Australian flying foxes over 3 years showing peak shedding and co-infections ...
doi.org
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Reposted by Jayna Raghwani
s4yandas.bsky.social
Sayan Das (he/him) @s4yandas.bsky.social · Jul 9
New in @science.org
We built a safe, atomic-resolution version of the Powassan virus—a deadly tick-borne #flavivirus with no vaccine.
✅ First structure ever
✅ Safe to handle (BSL-2)
✅ Platform for vaccines & antivirals

Let me show you 🧵 (1/5)

Link: www.science.org/doi/10.1126/...
Atomic-resolution structure of a chimeric Powassan tick-borne flavivirus
The 2.8-Å resolution structure is presented for a chimeric construct of an emerging tick-borne flavivirus, Powassan virus.
www.science.org
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Reposted by Jayna Raghwani
socialinfluenza.bsky.social
Ed Hutchinson @socialinfluenza.bsky.social · Jul 4
Are you doing a PhD or research Masters in Virology? Want to be part of a community of like-minded researchers from across the UK and Ireland?

We're excited to announce the first annual conference run by and for postgraduate research students in Virology. Please sign up, and please spread the word!
pgvironetwork.bsky.social
Postgraduate Virologists Network @pgvironetwork.bsky.social · Jul 1
Registration for our 2025 meeting is now OPEN!

To register for the meeting (£50 per person, includes buffet lunch and refreshments on both days) please use this link: www.eventbrite.co.uk/e/postgradua...
Postgraduate Virologists Network Conference 2025
A two day community meeting for postgraduate virology researchers, held at the University of Glasgow on the 8th - 9th September 2025
www.eventbrite.co.uk
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Reposted by Jayna Raghwani
erinharvey.bsky.social
Erin Harvey @erinharvey.bsky.social · Jul 2
Interested in metagenomic virus discovery but don't know where to start? In collaboration with CERI and a group of virus discovery experts from around the world, we'll be running a 5 day hands-on workshop in virus discovery.
Find out more here: climade.health/2025/06/22/m...
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Reposted by Jayna Raghwani
hansonmark.bsky.social
Mark A. Hanson @hansonmark.bsky.social · Jun 10
New from The Strain Team:
🎊 Springer Nature Discovers MDPI 🎊

Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗).

Gross! 😀 1/n

#ResearchIntegrity #SciPub #AcademicSky
Spinger Nature Discovers MDPI – The Strain on Scientific Publishing
Home page for the paper ‘The Strain on Scientific Publishing’ by Mark A Hanson, Dan Brockington, Paolo Crosetto and Pablo Gomez Barreiro
the-strain-on-scientific-publishing.github.io
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Reposted by Jayna Raghwani
chrisillingworth.bsky.social
Chris Illingworth @chrisillingworth.bsky.social · May 28
We have a job going for a bioinformatician / computational biologist at the CVR in Glasgow. www.jobs.gla.ac.uk/job/computat...
Computational Biologist/Bioinformatician
Computational Biologist/Bioinformatician COLLEGE OF MVLSSchool of Infection and Immunity Job PurposeThe post holder will join the Bioinformatics group at the School of Infection and Immunity, MRC-U...
www.jobs.gla.ac.uk
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Reposted by Jayna Raghwani
Thelonevirologist @thelonevirologist.bsky.social · May 27
Ecology and evolutionary trajectories of morbilliviruses in Neotropical bats

www.nature.com/articles/s41...
Ecology and evolutionary trajectories of morbilliviruses in Neotropical bats - Nature Microbiology
Investigations in wild bats and non-human primates in Brazil and Costa Rica inform about diverse Morbillivirus ecology in neotropical bats and host jumps, and about zoonotic potential of morbillivirus...
www.nature.com
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Reposted by Jayna Raghwani
uofgecodatasci.bsky.social
Ecological Data Science @uofgecodatasci.bsky.social · May 15
📣🚨📣Deadline extended to 6th June 2025! 📣🚨📣
Applications are still open for our MSc+PhD scholarships in Ecological Data Science available to those from underrepresented groups. This offers fully funded MSc (full UK fees and UKRI stipend) followed by entry to our 4-year PhD programme.
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Reposted by Jayna Raghwani
iddjobs.org
IDDjobs @iddjobs.org · Apr 30
Postdoc (Washington DC, USA)
Rodent-borne virus risk in heterogeneous landscapes
with @clfaust.bsky.social @jraghwani.bsky.social @bahanbug.bsky.social
at @ox.ac.uk @uofglasgow.bsky.social @royalvetcollege.bsky.social @ilri.org...
More details: http://iddjobs.org/jobs/2307
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Reposted by Jayna Raghwani
btobirds.bsky.social
BTO | British Trust for Ornithology @btobirds.bsky.social · Apr 30
BTO's Hugh Hanmer, Senior Research Ecologist, is a speaker at this webinar where he'll be discussing the decline in Blackbirds in the UK and the spread of Usutu virus. Sign up to attend on the link below. ⬇️
bes-parasitesgroup.bsky.social
BES - Parasites and Pathogens group @bes-parasitesgroup.bsky.social · Apr 29
📢🐦 Join us this June for our first free webinar!

"Diseases in Wild Birds: A One Health Perspective"

Where: online, free
When: 9th June 2025

Speakers, info & registration ⬇️
www.britishecologicalsociety.org/content/dise...

@britishecologicalsociety.org @rspb.bsky.social @btobirds.bsky.social
Diseases in Wild Birds: A One Health Perspective - British Ecological Society
Join the Parasites and Pathogens SIG for this webinar covering the implications of the range of diseases present in the wild bird population.
www.britishecologicalsociety.org
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Reposted by Jayna Raghwani
jameshassell.bsky.social
James Hassell @jameshassell.bsky.social · Apr 26
📣 We’re hiring! 2-yr postdoc at Smithsonian’s NZCBI on an NSF-funded project with partners incl. Glasgow, RVC, Uganda MOH, Cary Institute. Focus: land use change, rodent movement, human-rodent contact, modeling disease risk, w/ plenty of fieldwork in Uganda. Details: tinyurl.com/SINSFR
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Reposted by Jayna Raghwani
tetherin.bsky.social
Stuart Neil @tetherin.bsky.social · Apr 23
New preprint from Luke Snell from GSTT, Suzanne Pickering in my lab and Rui Galao, my colleague at KCL.

Here we examine in detail the evolution of the SARS CoV-2 spike in persistent infections, and essentially catch a potential variant in the act of developing. 1/n

www.biorxiv.org/content/10.1...
Antibody escape drives emergence of diverse spike haplotypes resembling variants of concern in persistent SARS-CoV-2 infections
Evolution of SARS-CoV-2 in long-term persistent infections is hypothesised to be a major source of variants of concern (VOC). However, the linkage of intra-host variants into haplotypes that reflect v...
www.biorxiv.org
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Jayna Raghwani @jraghwani.bsky.social · Apr 22
Just over a week left to the London Infection Ecology Network event at the RVC with a fantastic list of speakers. For further info and to grab your tickets: www.eventbrite.co.uk/e/london-inf...
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Jayna Raghwani @jraghwani.bsky.social · Apr 18
This free, in-person event is open to researchers based in London or nearby areas. The afternoon will feature a series of talks exploring exciting topics at the intersection of ecology, evolution, and infectious disease.

cc: @lien-london.bsky.social
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Jayna Raghwani @jraghwani.bsky.social · Apr 18
📣 Excited annouce that the next London Infection Ecology Network (LIEN)🦠🌎🧪🌳🌤️ in-person event is taking place on April 30th at the RVC (Camden)!

If you’d like to attend, please register for a free ticket via Eventbrite:
🔗 www.eventbrite.co.uk/e/london-inf...
London Infection and Ecology Meeting
LIEN fosters interdisciplinary collaboration between ecology and health sciences, supporting inclusive research and innovation.
www.eventbrite.co.uk
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Reposted by Jayna Raghwani
eveliinahanski.bsky.social
Eveliina Hanski @eveliinahanski.bsky.social · Apr 10
We compared gut microbiota across >800 lab and wild house mice. Wild mice have more diverse, aerotolerant, and dynamic microbiotas than their lab counterparts. See our latest paper here: bmcmicrobiol.biomedcentral.com/articles/10.... #gutmicrobiome #musmusculus #wildmice
Wild house mice have a more dynamic and aerotolerant gut microbiota than laboratory mice - BMC Microbiology
The mammalian gut microbiota is a complex microbial community with diverse impacts on host biology. House mice (Mus musculus) are the major model organism for research on mammals, but laboratory domes...
bmcmicrobiol.biomedcentral.com
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Reposted by Jayna Raghwani
rdrpsummit.bsky.social
RdRp Summit @rdrpsummit.bsky.social · Apr 3
EXCITING NEWS🥳! @isme-microbes.bsky.social is now sponsoring 3 travels grants worth EUR 500 each to support early career researchers presenting at the #RdRpSummit2025.
Abstract submissions & registrations are still open!✍️
More info at RdRp.io
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Reposted by Jayna Raghwani
stn-wame.bsky.social
stn-wame.bsky.social @stn-wame.bsky.social · Apr 8
We are excited to announce a support scheme for ECRs wishing to attend ESEB 2025 and participate in the WAME-sponsored symposium “Contribution of the microbiome to host adaptation and plasticity”

See here for more details and please share!

www.wamestn.com/eseb-2025
ESEB 2025 — wild animal microbiome evolution
www.wamestn.com
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Reposted by Jayna Raghwani
ecoevodom.bsky.social
Dominik Melville @ecoevodom.bsky.social · Apr 3
Did you know coronavirus infections impact the gut microbial community of #bats? But the effect differs between viruses. Published in @ismepublications.bsky.social - Big team effort: @alice-risely.bsky.social @cdrosten.bsky.social @vmcorman.bsky.social et al. academic.oup.com/ismecommun/a...
Hibecovirus (genus Betacoronavirus) infection linked to gut microbial dysbiosis in bats
Abstract. Little is known about how zoonotic virus infections manifest in wildlife reservoirs. However, a common health consequence of enteric virus infect
academic.oup.com
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Reposted by Jayna Raghwani
evogytis.bsky.social
Gytis Dudas @evogytis.bsky.social · Apr 3
We're looking for a PhD student to join us at Vilnius University in Lithuania. We work on RNA virus evolution computationally but we'd like to generate more mosquito RNA virus sequence data. Official ad: www.gmc.vu.lt/en/doctoral-.... Please share & continue reading if interested.
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Reposted by Jayna Raghwani
emcat1.bsky.social
Emma Thomson @emcat1.bsky.social · Mar 27
New in Nature Comms: We applied metagenomic + targeted NGS to serum from febrile patients in Uganda. Post-COVID, LMICs have sequencing infrastructure that could be repurposed for pathogen discovery.
🔗 www.nature.com/articles/s41...
Uncovering the viral aetiology of undiagnosed acute febrile illness in Uganda using metagenomic sequencing - Nature Communications
Acute febrile illness is common in sub-Saharan Africa and causative agents are often unknown. Here, the authors perform metagenomic sequencing on samples from patients with acute febrile illness in Ug...
www.nature.com
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