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Reposted by Camila Valenzuela, PhD

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 8d

The unique lipopolysaccharide composition of Salmonella Typhimurium ST313 dampens pyroptosis and inflammasome activation and suppresses host cell death https://www.biorxiv.org/content/10.1101/2025.09.29.679141v1

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Reposted by Camila Valenzuela, PhD

Richard Sever @richardsever.bsky.social · 13d

Link to HHMI preprint mandate hhmicdn.blob.core.windows.net/policies/Imm...

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Reposted by Camila Valenzuela, PhD

Pedro Escoll @pescoll.bsky.social · Sep 5

New preprint in the lab! How the mitochondrial ETC works during infection of human macrophages with #Legionella or #Salmonella? Spoiler: there are some similarities and also pathogen-specific differences. Work led by Francisco Garcia and Paula Martínez, with @cbuch.bsky.social at @pasteur.fr

Figure 5. Working model for pathogen-specific ETC modulations that preserve the ∆ψm in hMDMs. (A) L. pneumophila: T4SS effectors dampen OxPhos early during
infection and preserve the ∆ψm by engaging the reverse mode of the FOF1 -ATPase. The ∆ψm remains high enough that ANT stays in forward mode, limiting cytosolic ATP
drain. All ETC complexes (I-IV) contribute to maintaining the ∆ψm. Complex I is uniquely essential during WT infection. (B) S. Typhimurium: T3SS SPI-1/2 effectors reduce
respiration and preserve the ∆ψm without inducing the reverse mode of the FO F1 -ATPase. Virulent bacteria rely on Complex I-driven electron entry with obligatory Complex
III/IV proton pumping, while Complex II contributes in all infection conditions. Secretion-defective mutants fail to establish the Complex I-dependent configuration.

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Reposted by Camila Valenzuela, PhD

Yersinia Research Unit @yersiniaunit.bsky.social · 15d

💊 🧬 Insightful dive into in-host bacterial evolution under antimicrobial pressure, a work from @csavin.bsky.social and @pierrelebury.bsky.social in our lab at @pasteur.fr

Institut Pasteur | 130 years of biomedical research @pasteur.fr · Aug 12

🦠 14 years, one patient, one superbug
@yersiniaunit.bsky.social scientists tracked Yersinia enterocolitica mutations as it developed antibiotic resistance over 14 years. Unprecedented view of bacterial evolution under treatment pressure 💊
pubmed.ncbi.nlm.nih.gov/40595576/
#AMR #yersinia

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Reposted by Camila Valenzuela, PhD

Enninga Lab @enningalab.bsky.social · 15d

Time for some insights into our latest #preprint

Using cryo–electron tomography, we peeked inside different #Mtuberculosis strains, and a couple of other mycobacteria.🧐 Surprise: some species, especially the host-adapted ones, build intracytoplasmic membranes (we call them MIMs)! 🦠

Enninga Lab @enningalab.bsky.social · 20d

🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫

Thread coming soon!

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 20d

Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1

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Reposted by Camila Valenzuela, PhD

Patrick Stotz @patrickstotz.bsky.social · 20d

More outstanding maps in this Mercator / 'Correct The Map' explainer by Reuters 😍
www.reuters.com/graphics/AFR...

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Reposted by Camila Valenzuela, PhD

SFM Microbial Pathogenesis @sfmpathogenesis.bsky.social · 19d

Mycobacterium tuberculosis forms nitrate-induced intracytoplasmic membranes (MIMs) that rewire metabolism & dampen inflammation during infection, uncovering a new layer of bacterial adaptation!
✍️ @camimille.bsky.social @enningalab.bsky.social @pasteur.fr
📖 shorturl.at/9kbDM

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Reposted by Camila Valenzuela, PhD

Christina Faherty @christinafaher1.bsky.social · 19d

Registration & abstract submissions are open for the #Shigella meeting! Travel grants available too! All are welcomed, whether you are active in #Shigella research or interested in the 21st century perspective on this formidable pathogen! 🦠 🧫 #Microsky
www.shigella2026.conferences-pasteur.org/home

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Reposted by Camila Valenzuela, PhD

The Shigella Meeting @shigellameeting.bsky.social · 20d

Come and join us in Paris 2026 to talk all about Shigella!

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Reposted by Camila Valenzuela, PhD

Arthur Lensen @arthurlensen.bsky.social · 20d

After years of hard work and months of growing MTB @camimille.bsky.social submitted her story ! Check this out if you wanna discover new intrabacterial structures and their function ! 🦠🔬✨

Enninga Lab @enningalab.bsky.social · 20d

🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫

Thread coming soon!

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 20d

Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1

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Reposted by Camila Valenzuela, PhD

Enninga Lab @enningalab.bsky.social · 20d

🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫

Thread coming soon!

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 20d

Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1

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Camila Valenzuela, PhD @kamovalenz.bsky.social · 20d

New preprint from the lab! Great work led by @camimille.bsky.social #mycobacterium #TB #cryoET

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 20d

Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1

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Reposted by Camila Valenzuela, PhD

Kate Baker @ksbakes.bsky.social · Jul 27

There are half a million cases of invasive non-Typhoidal Salmonella (iNTS) every year and while you might know S. Typhimurim and Enteritidis, you may not have heard of S. Panama 💩 🩸 🧫 💊 Check out our latest in @lancetmicrobe.bsky.social doi.org/10.1016/j.la... and the 🧵 below to find out more 1/n

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Reposted by Camila Valenzuela, PhD

The Company of Biologists @biologists.bsky.social · Sep 4

Win £200 for your post on the Node!

Do you have an idea for a post on the Node that you have been postponing for a while?

Post your piece by 30 September. One winner will be randomly selected for a prize of £200 and an interview with the Node.

Find out more: thenode.biologists.com/the-node-wri...

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Camila Valenzuela, PhD @kamovalenz.bsky.social · Sep 4

Anyway, go take a look! There will be some media coverage, I will add to this thread once it’s out!

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Camila Valenzuela, PhD @kamovalenz.bsky.social · Sep 4

Moreover, something we discussed a lot about as it was extremely intriguing at the beginning, it seems that there is a strong level of cellular adaptation when demethylation is slow and gradual vs when it’s fast!

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Camila Valenzuela, PhD @kamovalenz.bsky.social · Sep 4

She worked so incredibly hard for this one and it shows! She showed that DNAme at the centromeres influences CENP-A localisation and centromere function

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Camila Valenzuela, PhD @kamovalenz.bsky.social · Sep 4

Focusing on something other than Salmonella for a minute, because my wife’s paper is just out and it is AMAZING! www.nature.com/articles/s41...

Congrats to all the authors, great work from the @dfachinetti.bsky.social @naltemose.bsky.social labs!

DNA methylation influences human centromere positioning and function - Nature Genetics

Genome-wide and targeted perturbation of DNA methylation at centromeres affects CENP-A positioning and centromere structure, resulting in aneuploidy and reduced cell viability.

www.nature.com

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Camila Valenzuela, PhD @kamovalenz.bsky.social · Sep 1

Sending you lots of strength, from me and the fur-babies!

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Reposted by Camila Valenzuela, PhD

Paul & Virginie - Centriole Lab @centriolelab.bsky.social · Aug 28

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

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Reposted by Camila Valenzuela, PhD

Science bytes @dnascience.bsky.social · Aug 17

Want 1,000 more steps a day?
Don’t buy a Fitbit.
Move to a walkable city.

A US-wide natural experiment shows people who moved to high-walkability areas added ~1,100 steps/day on average, regardless of age, gender, or BMI. www.nature.com/articles/s41...

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Reposted by Camila Valenzuela, PhD

Andres Meza @nbody6.bsky.social · Aug 13

Una vez golpista, siempre golpista ☝🏼

Trini Lathrop @mattyll.bsky.social · Aug 13

«Gobernar todo lo posible por decreto», dice la candidata Matthei.

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Reposted by Camila Valenzuela, PhD

La Enzima Inquieta 🏳️‍🌈🏳️‍⚧️ @viajandoconciencia.bsky.social · Aug 13

Con estos incendios forestales seguramente escucharéis a gente decir que hay que limpiar el monte
En esta entrada de mi blog os explico por qué limpiar el monte no sólo no ayuda sino que empeora la situación

La importancia botánica de la zona del Valle de Toledo

La zona del Valle de Toledo es una parte del lugar de interés geológico del «Torno» del Tajo en Toledo. Además de su interesante geología, también alberga especies botánicas de gran valor y es un l…

viajandoconcienciahome.wordpress.com

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Reposted by Camila Valenzuela, PhD

Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · Aug 12

Check out 🧐 our new preprint 📜:
www.biorxiv.org/content/10.1...
Congrats🎉 to @vasilgaisin.bsky.social and Corina Hadjicharalambous, who studied contractile injection systems directly in hot spring♨️ bacterial mats🦠
#microsky #teamtomo #Chloroflexota

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Reposted by Camila Valenzuela, PhD

Institut Pasteur | 130 years of biomedical research @pasteur.fr · Aug 5

France faces unprecedented chikungunya outbreak with first locally acquired cases detected in June - earliest on record. #chikungunya ↘️

Summer 2025: early emergence of chikungunya in mainland France

An unprecedented situation has arisen this summer, with the first locally acquired cases of chikungunya detected as early as June, notably affecting the Grand Est region for the very first time. Chiku...

www.pasteur.fr

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