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Reposted by Paul & Virginie - Centriole Lab

Ali Shaib @alishaib.bsky.social · 8d

#GEF25 Concluding Plenary Lecture with the wonderful Virginie Hamel.

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Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 8d

😂

Reposted by Paul & Virginie - Centriole Lab

Christophe 🔬 L @christlet.bsky.social · 8d

The ExM gang @jvermot.bsky.social @mahjoublab.bsky.social @marinelap.bsky.social @centriolelab.bsky.social @simonemortal.bsky.social et al #GEF25

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Reposted by Paul & Virginie - Centriole Lab

Boris Sieber @borissieber.bsky.social · 13d

Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction!

Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1

doi.org/10.1101/2025...

Schematic of MAPK signalling in fission yeast, budding yeast and Metazoa. No MAPK scaffold was known for ERK-like MAPK in fission yeast, as opposed to budding yeast Ste5 and metazoan KSR1/2.

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Reposted by Paul & Virginie - Centriole Lab

Júlia Garcia-Baucells @jugarbau.bsky.social · 19d

 1/6 Extremely happy to share my PhD work is out on bioRxiv! We discovered that microtubules deform mitotic centrosomes. When we removed them, the SPD-5 scaffold became denser but didn't lose material. This suggests it's an elastically deformable solid! This only happens in mitosis.

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Reposted by Paul & Virginie - Centriole Lab

Tea Tomita @teagondii.bsky.social · 19d

[We are Hiring!]

The Weiss Lab at Albert Einstein College of Medicine (NY) is hiring a Postdoc Scientist to explore the Toxoplasma gondii cyst wall using XL-MS, Split TurboID, & U-ExM.

This project aims to unlock new strategies for treating toxoplasmosis.

DM for more info!

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Reposted by Paul & Virginie - Centriole Lab

Armando Rubio Ramos @bioarm.bsky.social · Sep 5

Lately I've been only posting images of really interesting protist here, but something that many don't know is that most of my time i'm expanding 'boring' mammalian cells and that I love human centrioles. Don't tell me that they are not beautiful😍👁️

#FluorescenceFriday #CellBiology #Cytoskeleton

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Reposted by Paul & Virginie - Centriole Lab

Emmanuel Levy's lab @elevylab.bsky.social · 22d

Years ago we discovered that missense mutations in homomeric proteins often induces their supramolecular assembly, as in the 📽️👇 - Are such aberrant assemblies of *folded* proteins toxic? Surprisingly, NO. Cells are amazingly robust systems! Paper now online @molsystbiol.org doi.org/10.1038/s443...

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Reposted by Paul & Virginie - Centriole Lab

MRC Laboratory of Molecular Biology @mrclmb.bsky.social · 20d

We’re looking for a #postdoc to join Lori Passmore’s group, within a programme aimed at understanding addition of mRNA poly(A) tails

More info: www.nature.com/naturecareer...
Closes 06 OCT
#ScienceJobs #PostdocJobs

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Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 23d

Be our new colleague! 🎉
The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor.

👉 More details here: lnkd.in/e8Z9eAm4
👉 Our department: mocel.unige.ch

Please feel free to share this opportunity with your network.

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Reposted by Paul & Virginie - Centriole Lab

Max-Planck-Gesellschaft @maxplanck.de · 23d

Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...

Graphic with a blue background and light green dots. The text 'call for applications' appears in green, and 'Ausschreibung' in white. A white arrow on the right points diagonally upward.

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Reposted by Paul & Virginie - Centriole Lab

Prevedel Lab @prevedel-lab.bsky.social · 25d

@embl.org Heidelberg is looking for a new Head of Scientific Instrumentation! This is an exciting opportunity at the interface between scientific research and technology development, overseeing our mechanical and electronic workshops!
embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

Head of Scientific Instrumentation Workshops

EMBL is a world leader in scientific research and at the forefront in the development of cutting-edge technologies. It operates across six sites in Heidelberg (headquarters), Barcelona, Cambridge, Gre...

embl.wd103.myworkdayjobs.com

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Reposted by Paul & Virginie - Centriole Lab

Lotte B. Pedersen @lottepedersen.bsky.social · 28d

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia: Current Biology www.cell.com/current-biol...

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia

Rezi et al. show that kinesin-3 KIF13B regulates ciliary protein content by promoting endocytic retrieval and small extracellular vesicle (EV) release of ciliary proteins while suppressing their relea...

www.cell.com

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Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 28d

🧬 New tool for U-ExM!
HAK-Actin is now available from Spirochrome → a reliable probe to label actin filaments in expansion microscopy.

Check it out at Spirochrome!
#UExM #Actin #Cytoskeleton #SuperResolution

Spirochrome @spirochrome.com · 28d

Discover HAK-actin™: A New Tool To Visualize The Actin Cytoskeleton by Expansion Microscopy

• Stronger signal via post-expansion labeling
• Broad cell lines & species compatibility
• Endogenous actin labeling
• Can be multiplexed with other targets

spirochrome.com/product/hak-...

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Reposted by Paul & Virginie - Centriole Lab

Spirochrome @spirochrome.com · 28d

Discover HAK-actin™: A New Tool To Visualize The Actin Cytoskeleton by Expansion Microscopy

• Stronger signal via post-expansion labeling
• Broad cell lines & species compatibility
• Endogenous actin labeling
• Can be multiplexed with other targets

spirochrome.com/product/hak-...

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Reposted by Paul & Virginie - Centriole Lab

Kat Toropova @kattoropova.bsky.social · 29d

The Dunn School PhD programme is live! 🎉

Two projects in our labs:
1) How the motor protein giant dynein-2 works
2) How signalling-essential membrane proteins get into cilia

Cryo-EM/ET, single mol & live-cell fluor microscopy, CRISPR-based genetic tools & more!

www.path.ox.ac.uk/study-with-u...

How to Apply - Dunn School

Here you can find more information on how to apply for our PhD programme, including deadlines and application requirements.

www.path.ox.ac.uk

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Reposted by Paul & Virginie - Centriole Lab

Biology-UNIGE @biology-unige.bsky.social · Sep 1

🏅Congratulations to Emeritus Prof. Ueli #Schibler for receiving the #Kappers Medal from the #EBRS: the Society’s highest honor, awarded for outstanding contributions to biological rhythms research @sciencesunige.bsky.social @mocel.bsky.social #UNIGE
ebrs-online.org/index.php/abou

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Reposted by Paul & Virginie - Centriole Lab

Lerit Lab @lablerit.bsky.social · Aug 19

@ascbiology.bsky.social Abstract submissions are open! Submit an abstract to the ‘Emerging concepts in centriole and centrosome assembly and function’ minisym. PRIZES for trainee talks & posters plus a mixer thanks to generous sponsors @jcellsci.bsky.social @dshb-antibodies.bsky.social & Nikon

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Reposted by Paul & Virginie - Centriole Lab

Omaya Dudin 𓂆 ¦🍉¦🦠¦🔬¦ @dudinlab.bsky.social · Aug 28

A new #UExM probe for #Actin!

Fun times thinking/developing/testing with @centriolelab.bsky.social & @lreymond.bsky.social !

Congrats to all !

If interested in #UExM, or #HAK-Actin, feel free to reach out !

Soon available at @spirochrome.com

#Expansion #Microscopy #ProtistsOnSky

Paul & Virginie - Centriole Lab @centriolelab.bsky.social · Aug 28

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

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Reposted by Paul & Virginie - Centriole Lab

Luc Reym⌬nd @lreymond.bsky.social · Aug 28

New preprint online!

So much fun working on this project, thank you @centriolelab.bsky.social and @dudinlab.bsky.social for embarking me on this one!

Hopefully HAK-actin will become your best companion for actin staining U-ExM expanded samples.

Paul & Virginie - Centriole Lab @centriolelab.bsky.social · Aug 28

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

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Paul & Virginie - Centriole Lab @centriolelab.bsky.social · Aug 28

Trouble imaging actin in ExM? Meet HAK-Actin, a probe for U-ExM, cryo-ExM & iU-ExM. Enables post-expansion labeling for max signal. www.biorxiv.org/content/10.1...
Soon at @spirochrome.com
Led by O.Mercey and @lreymond.bsky.social, in collab with @dudinlab.bsky.social and @marinelap.bsky.social

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Reposted by Paul & Virginie - Centriole Lab

Biozentrum, University of Basel @biozentrum.unibas.ch · Aug 26

🧪 The University of Basel is setting up a new endowed professorship in #ClimateBiophysics at the @biozentrum.unibas.ch, funded by the Georg H. Endress Foundation. This new professorship strengthens climate research @unibas.ch. www.biozentrum.unibas.ch/news/detail/...

New endowed professorship strengthens climate research at the University of Basel

The University of Basel is setting up a new endowed professorship at the Biozentrum to make fundamental discoveries at the interface between biophysics and climate-relevant environmental biology. This...

www.biozentrum.unibas.ch

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Reposted by Paul & Virginie - Centriole Lab

Biology-UNIGE @biology-unige.bsky.social · Aug 22

Congratulations @elevylab.bsky.social and collaborators for your latest publication in Cell 👏 and welcome to BlueSky 🦋@mocel.bsky.social‬ @sciencesunige.bsky.social

Alexey Amunts @amunts.bsky.social · Aug 22

Emmanuel Levy @elevylab.bsky.social has joined BlueSky 🌟 with a fantastic Cell paper with Shu-ou Shan, showing the interactome of the TOM complex and how cotranslational mito import prioritizes large globular domains. Beautiful science!
Give him a warm welcome 🎉
link: www.cell.com/cell/fulltex...

Principles of cotranslational mitochondrial protein import

Selective ribosome profiling reveals that nearly 20% of mitochondrial proteins in human cells are imported during translation on cytosolic ribosomes. Cotranslational import requires an N-terminal pres...

www.cell.com

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Reposted by Paul & Virginie - Centriole Lab

Ana Almeida @ac-almeida.bsky.social · Jul 30

🔎New preprint!
We reveal a physiological role for tubulin autoregulation, fine-tuning microtubule dynamics and preserving 3D cellular architecture.
Big thanks to @ivanagasic.bsky.social and team!
Link below for all #cytoskeleton & #spheroid enthusiasts👇(1/5)
www.biorxiv.org/content/10.1...

Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability

Alpha- and beta-tubulin heterodimers dynamically assemble into microtubules, key cytoskeletal elements involved in intracellular trafficking, cell adhesion and division. The availability of free tubul...

www.biorxiv.org

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Reposted by Paul & Virginie - Centriole Lab

Jordan Raff @jordanraff.bsky.social · Jul 31

The Dunn School is a really great environment for taking up a Career Development Fellowship, and we are looking for candidates! Please spread the word.

The Dunn School, Oxford @dunnschool.bsky.social · Jul 30

📣 Applications now open 📣

We are seeking outstanding ECRs looking for a stimulating and supportive environment in which to establish their research group as externally-funded fellows, in any area or cell or molecular biology underlying disease!

Please share!

www.path.ox.ac.uk/work-with-us...

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