Lightnews — Scholar-powered news

Lotte B. Pedersen @lottepedersen.bsky.social · 8d

Congratulations!👏👏

Reposted by Lotte B. Pedersen

(GIRISH)MALI LAB @dyneinassembly.bsky.social · 9d

Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia.

Open access link below:
www.nature.com/articles/s41...

Here's a cool animated summary

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Reposted by Lotte B. Pedersen

hansenjn @hansenjn.bsky.social · 11d

So proud and happy to share that our study on the #proteome, heterogeneity, and cell-type specificity of primary #cilia is published now at Cell 🎉

Big thank you to all the many people that made this possible, at the Lundberg Lab, Human Protein Atlas, Lindstrand lab, and Hsien-Sheu lab.

Cell - a Cell Press journal @cp-cell.bsky.social · 12d

Now online! Intrinsic heterogeneity of primary cilia revealed through spatial proteomics

Intrinsic heterogeneity of primary cilia revealed through spatial proteomics

An antibody-based spatial proteomics screen on human primary cilia explores 715 proteins across single cilia of different cell types and reveals extensive cell-type specificity, single-cilium heterogeneity, ciliary microdomains, CFAP300 as a new cilium marker protein, 91 novel proteins including CREB3, and a CREB3 variant associated to ciliopathy phenotypes.

dlvr.it

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Reposted by Lotte B. Pedersen

Stacey Ogden 🦔 @labogden.bsky.social · 19d

Am I oddly excited to learn about the tree that @jcellsci.bsky.social protected in the Forest of Biologists in recognition of my peer review? Yes. 🤓

forest.biologists.com/landscape/?i...

Landscape - The Forest of Biologists

forest.biologists.com

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Lotte B. Pedersen @lottepedersen.bsky.social · 17d

Looks yummi 😋

Lotte B. Pedersen @lottepedersen.bsky.social · 17d

Thank you to our @ukcilianetwork.bsky.social friends for organising a fantastic meeting! It was an honour to participate, present our work and meet old and new cilia friends 😊

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Reposted by Lotte B. Pedersen

Lerit Lab @lablerit.bsky.social · 21d

We are hiring! We are currently interviewing for an entry level staff position in the lab, but it is not too late to submit a postdoc application! Send a note of interest to me and apply here: bit.ly/3VmmM7m

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Lotte B. Pedersen @lottepedersen.bsky.social · 20d

Congratulations Wallace!👏👏

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Reposted by Lotte B. Pedersen

Soni Lacefield @lacefieldlab.bsky.social · Aug 27

My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438
@dartmouthbcb.bsky.social @futurepislack.bsky.social

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

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Reposted by Lotte B. Pedersen

Paul & Virginie - Centriole Lab @centriolelab.bsky.social · 23d

Be our new colleague! 🎉
The Dept of Molecular and Cellular Biology at the University of Geneva is hiring an Assistant Professor or Associate Professor.

👉 More details here: lnkd.in/e8Z9eAm4
👉 Our department: mocel.unige.ch

Please feel free to share this opportunity with your network.

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Lotte B. Pedersen @lottepedersen.bsky.social · 26d

Congratulations! 👏👏🎉🥂

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Reposted by Lotte B. Pedersen

Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 26d

I’m biased 🇩🇰, but this is quite nice to read:

I thought science hinged on prestige. Moving abroad made me reassess my priorities

www.science.org/content/arti...

I thought science hinged on prestige. Moving abroad made me reassess my priorities

In Denmark, this Ph.D. student fell in love with an egalitarian society that values work-life balance

www.science.org

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Reposted by Lotte B. Pedersen

Kat Toropova @kattoropova.bsky.social · Sep 8

The Dunn School PhD programme is live! 🎉

Two projects in our labs:
1) How the motor protein giant dynein-2 works
2) How signalling-essential membrane proteins get into cilia

Cryo-EM/ET, single mol & live-cell fluor microscopy, CRISPR-based genetic tools & more!

www.path.ox.ac.uk/study-with-u...

How to Apply - Dunn School

Here you can find more information on how to apply for our PhD programme, including deadlines and application requirements.

www.path.ox.ac.uk

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Reposted by Lotte B. Pedersen

(GIRISH)MALI LAB @dyneinassembly.bsky.social · 29d

The annual Dunn School DPhil studentship competition for 2026 is open for applications.

We have a project aimed at understanding the molecular mechanisms of ciliary dynein transport. See details below and please pass on to anyone who might be interested.

www.path.ox.ac.uk/project/mech...

Mechanistic studies on axonemal dynein transport to motile cilia - Dunn School

Over 30 groups work at the Dunn School to uncover the molecular and cellular mechanisms underlying disease. Discover which research groups are accepting students for our next round of applications.

www.path.ox.ac.uk

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Lotte B. Pedersen @lottepedersen.bsky.social · 28d

Our story on KIF13B #cilia #extracellular vesicles is now out in Current Biology 🤩
Thanks to past and present team members involved, collaborators and funding sources 🙏
@sorentc.bsky.social
@novo-nordisk.bsky.social
@theracilproject.bsky.social
@carlsbergfondet.dk
@FOR5547.bsky.social

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Lotte B. Pedersen @lottepedersen.bsky.social · 28d

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia: Current Biology www.cell.com/current-biol...

KIF13B controls ciliary protein content by promoting endocytic retrieval and suppressing release of large extracellular vesicles from cilia

Rezi et al. show that kinesin-3 KIF13B regulates ciliary protein content by promoting endocytic retrieval and small extracellular vesicle (EV) release of ciliary proteins while suppressing their relea...

www.cell.com

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Reposted by Lotte B. Pedersen

The EMBO Journal @embojournal.org · Sep 1

Primary #cilia dysfunction as in Bardet-Biedl syndrome compromises normal adipogenic differentiation in favor of fibrogenic transition, predisposing to obesity
@wachtenlab.bsky.social and collaborators
www.embopress.org/doi/full/10....

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Reposted by Lotte B. Pedersen

Elif Nur Firat-Karalar @cytolabkoc.bsky.social · Aug 26

New paper on DYRK kinases and primary cilium!
This project began with our interest in DYRK3’s relationship to centriolar satellites. But what started as a CS-focused story soon evolved into studying DYRK kinase activity during ciliogenesis.
nature.com/articles/s42...

Kinase activity of DYRK family members is required for regulating primary cilium length, stability and morphology - Communications Biology

DYRK3 kinase interacts with multiple centriolar satellites and ciliary components to regulate axoneme length dynamics in cooperation with DYRK2.

nature.com

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Lotte B. Pedersen @lottepedersen.bsky.social · Aug 18

Congratulations Barbara and team! 👏👏

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Reposted by Lotte B. Pedersen

Journal of Cell Biology @jcb.org · Aug 13

With a combination of FIB-SEM, super-resolution & expansion #microscopy, Araujo Alves, Bastin et al @bastinlab.bsky.social @pasteur.fr reveal how IFT trains are progressively restricted to a limited number of #microtubule doublets in the flagellum of T. brucei. rupress.org/jcb/article/...

#Cilia

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Reposted by Lotte B. Pedersen

EuroCilia2027 @eurocilia.bsky.social · Aug 11

Have you saved the date for #Cilia2027?
It is going to be in March 2027 at this lake near #Milan. 👇

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Reposted by Lotte B. Pedersen

UK Cilia and Centrosome Network @ukcilianetwork.bsky.social · Aug 13

This has always been a fantastic community driven meeting. It is also a rare forum for scientists, patients and clinicians to come together to come up with solutions to solve the biggest challenges facing the cilia community and fill knowledge gaps. All cilia enthusiasts - mark your calendars!

EuroCilia2027 @eurocilia.bsky.social · Aug 11

Have you saved the date for #Cilia2027?
It is going to be in March 2027 at this lake near #Milan. 👇

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Reposted by Lotte B. Pedersen

TanentzapfLab @tanentzapflab.bsky.social · Aug 13

The goal of a PhD is not to learn some facts or read a few papers or learn a bunch of techniques. The goal of a PhD is to learn independence, problem solving, how to finish things you start, resilience, & gain the ability to adapt & think creatively. Learning these things is hard.

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Reposted by Lotte B. Pedersen

Nathalie Jurisch-Yaksi @nathaliejuya.bsky.social · Aug 14

🚩Publication Alert🚩"Advection vs. Diffusion in Brain Ventricular Transport" by Herlyng at al in collaboration with @utropstegn.bsky.social at @simularesearch.bsky.social and Jebsen Centre for Brain Fluid Research is now published in Fluids and Barriers of the CNS! 🧠💧

Advection versus diffusion in brain ventricular transport - Fluids and Barriers of the CNS

Cerebrospinal fluid (CSF) is integral to brain function. CSF provides mechanical support for the brain and helps distribute nutrients, neurotransmitters and metabolites throughout the central nervous ...

doi.org

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Lotte B. Pedersen @lottepedersen.bsky.social · Aug 14

Congratulations Nathalie and team!

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