Krishanu Dey Das
@kdeydas.bsky.social
Grad student in IISER Thiruvananthapuram, India. Working on Golgi and stress response.
Recent publications from Prof. Murty Lab, IISER Thiruvananthapuram. Congratulations to all the authors
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting mitofusin 2
Highlighted Article: The endosomal ubiquitin ligase RFFL associates with and primes mitochondria for PRKN recruitment, targets mitofusins for degradation and contributes to mitochondrial networks and ...
journals.biologists.com
June 28, 2025 at 11:17 AM
Recent publications from Prof. Murty Lab, IISER Thiruvananthapuram. Congratulations to all the authors
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Reposted by Krishanu Dey Das
#GRASP55 isn't just structural—it helps lysosomal enzymes get where they’re going. New research shows that knocking out GRASP55 leads to immature β-hexosaminidase A (HEXA) being misrouted and secreted instead of reaching the lysosome. www.molbiolcell.org/doi/10.1091/... #ASCB #CellBiology #Lysosomes
June 6, 2025 at 6:47 PM
#GRASP55 isn't just structural—it helps lysosomal enzymes get where they’re going. New research shows that knocking out GRASP55 leads to immature β-hexosaminidase A (HEXA) being misrouted and secreted instead of reaching the lysosome. www.molbiolcell.org/doi/10.1091/... #ASCB #CellBiology #Lysosomes
Reposted by Krishanu Dey Das
Do you want to hear the latest and greatest about the neuronal cytoskeleton? Join us in Chile next April for #NeuroCyto2025, organized by @monicamsousa.bsky.social, Kassandra Ori-McKenney and Tomás Falzone! Registration is open until March 5: neurocytoskeleton.com/2025/
January 12, 2025 at 2:57 PM
Do you want to hear the latest and greatest about the neuronal cytoskeleton? Join us in Chile next April for #NeuroCyto2025, organized by @monicamsousa.bsky.social, Kassandra Ori-McKenney and Tomás Falzone! Registration is open until March 5: neurocytoskeleton.com/2025/
Reposted by Krishanu Dey Das
Poster presentation at ASCB|EMBO Cell Bio 24 conference at San Diego
December 18, 2024 at 1:32 AM
Poster presentation at ASCB|EMBO Cell Bio 24 conference at San Diego
Reposted by Krishanu Dey Das
Reposted by Krishanu Dey Das
ÅNGSTRÖM-RESOLUTION FLUORESCENCE MICROSCOPY.
Can we do structural biology with an optical microscope? Yes!
Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out on 24.05.2023 in Nature! @natureportfolio.bsky.social
[re-post from Twitter]
Can we do structural biology with an optical microscope? Yes!
Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out on 24.05.2023 in Nature! @natureportfolio.bsky.social
[re-post from Twitter]
Ångström-resolution fluorescence microscopy - Nature
The authors introduce a single-molecule DNA-barcoding method, resolution enhancement by sequential imaging, that improves the resolution of fluorescence microscopy down to the Ångström scale using off...
www.nature.com
November 27, 2024 at 9:47 AM
ÅNGSTRÖM-RESOLUTION FLUORESCENCE MICROSCOPY.
Can we do structural biology with an optical microscope? Yes!
Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out on 24.05.2023 in Nature! @natureportfolio.bsky.social
[re-post from Twitter]
Can we do structural biology with an optical microscope? Yes!
Check out how we resolved *single bases of DNA* and much more using fluorescence microscopy, out on 24.05.2023 in Nature! @natureportfolio.bsky.social
[re-post from Twitter]
Reposted by Krishanu Dey Das
Microscopy/live imaging people! Need your help 😅
I’ve only just recently started working with large time series files (1,000+ slices) and don’t know where to start when it comes to rendering and exporting them. What software(s) do you use?
I’ve only just recently started working with large time series files (1,000+ slices) and don’t know where to start when it comes to rendering and exporting them. What software(s) do you use?
November 27, 2024 at 4:54 PM
Microscopy/live imaging people! Need your help 😅
I’ve only just recently started working with large time series files (1,000+ slices) and don’t know where to start when it comes to rendering and exporting them. What software(s) do you use?
I’ve only just recently started working with large time series files (1,000+ slices) and don’t know where to start when it comes to rendering and exporting them. What software(s) do you use?
Reposted by Krishanu Dey Das
🔬 Are you eager to dive into the world of light microscopy & learn from top-notch microscopists about its essential techniques for life science applications? If that sounds exciting, don’t miss out on this free, in-depth iBiology series! 👉 www.ibiology.org/online-biolo...
November 16, 2024 at 5:19 PM
🔬 Are you eager to dive into the world of light microscopy & learn from top-notch microscopists about its essential techniques for life science applications? If that sounds exciting, don’t miss out on this free, in-depth iBiology series! 👉 www.ibiology.org/online-biolo...
Reposted by Krishanu Dey Das
Pure autofluorescence from the midband crystalline cones in a mantis shrimp eye. The fluorescence comes from mycosporine like amino acid pigments that absorb specific bands of UV light, thus tuning the UV sensitivity of the photoreceptors they focus light into. 🧪
#FluorescenceFriday
#FluorescenceFriday
November 15, 2024 at 2:18 PM
Pure autofluorescence from the midband crystalline cones in a mantis shrimp eye. The fluorescence comes from mycosporine like amino acid pigments that absorb specific bands of UV light, thus tuning the UV sensitivity of the photoreceptors they focus light into. 🧪
#FluorescenceFriday
#FluorescenceFriday
Host cells take different kind of steps to fight infection. One such least understood intercellular structure is ALIS. Here Anushree et. al shows that ALIS indeed help in elimination of intracellular bacteria and also sequesters many anti-microbial peptides.
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
TLR-mediated aggresome-like induced structures comprise antimicrobial peptides and attenuate intracellular bacterial survival | Molecular Biology of the Cell
Immune cells employ diverse mechanisms for host defense. Macrophages, in response to TLR activation, assemble aggresome-like induced structures (ALIS). Our group has shown TLR4-signaling transcription...
www.molbiolcell.org
November 12, 2024 at 3:19 PM
Host cells take different kind of steps to fight infection. One such least understood intercellular structure is ALIS. Here Anushree et. al shows that ALIS indeed help in elimination of intracellular bacteria and also sequesters many anti-microbial peptides.
www.molbiolcell.org/doi/full/10....
www.molbiolcell.org/doi/full/10....
Golgi is pretty interesting organelle. Its regulation by PTM like ubiquitination is also pretty cool. Here’s the recent paper from our lab, which shows involvement of endosome associated ubiquitin E3 ligase in maintaining Golgi architecture.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
November 12, 2024 at 3:15 PM
Golgi is pretty interesting organelle. Its regulation by PTM like ubiquitination is also pretty cool. Here’s the recent paper from our lab, which shows involvement of endosome associated ubiquitin E3 ligase in maintaining Golgi architecture.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...